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General Psychiatry 2024年第2期37卷 306-310页

作者： Dianying Liu Gang Lei Hongdong Deng Xiangyang Zhang Yonghui dang College of Medicine&Forensics Xi'an Jiaotong University Health Science CenterXi'anShaanxiChina Ganzhou City Key Laboratory of Mental Health The Third People's Hospital of Ganzhou CityGanzhouJiangxiChina Institute of Psychology Chinese Academy of SciencesBeijingChina

To the editor:Mood disorders(MD)are serious mental illnesses that commonly affect adolescents,leading to a high incidence of suicidal behaviour.1 In China,the suicide attempt(SA)rate for adolescents with MD is 51.96%,2 and over 500000 adolescent SA are reported annually in the USA due to depression.3 Risk factors for SA include gender,hormone levels,family conflict and,particularly,negative cognitive styles such as rumination.

关键词： adolescent disorders annually

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气候变化背景下内保温砖墙热湿性能对比

东南大学学报（自然科学版） 2024年第2期54卷 441-446页

作者：党新元 Department of Civil Engineering KU LeuvenLeuven 3001Belgium

为量化气候变化背景下内保温砖墙的热湿性能,采用数值模拟软件WUFI Pro,对比湿气密闭性保温墙体、湿气透过性内保温墙体和未保温墙体,分析其在比利时鲁汶1种现状气候工况和2种未来气候工况下的冻融循环风险、霉菌滋生风险、热损失和湿负... 详细信息

为量化气候变化背景下内保温砖墙的热湿性能,采用数值模拟软件WUFI Pro,对比湿气密闭性保温墙体、湿气透过性内保温墙体和未保温墙体,分析其在比利时鲁汶1种现状气候工况和2种未来气候工况下的冻融循环风险、霉菌滋生风险、热损失和湿负荷.结果表明,湿气透过性保温墙体与湿气密闭性保温墙体的冻融风险次数由现状气候工况下的6和2次升至未来气候工况下的16和13次,且含水率显著增高,而未保温墙体无风险.湿气密闭性保温墙体在3种工况下的霉菌滋生风险都显著高于其余2种墙体,且在未来气候工况下风险更高.含保温层墙体的能耗显著低于未保温墙体,湿气透过性保温墙体与未保温墙体在未来气候工况下需要更大的湿负荷.

关键词：气候变化砖墙内保温热湿性能

Mitochondria-targeted Janus mesoporous nanoplatform for tumor photodynamic therapy

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Chinese Chemical Letters 2024年第2期35卷 544-547页

作者： Min Dong Rui Tang Jing Li Jiajia Zhao Yu Wang Lin Ouyang Wei Lu Jun Tao Meng dang Yuxia Tang Zhaogang Teng Key Laboratory for Organic Electronics & Information Displays and Jiangsu Key Laboratory for Biosensors Institute of Advanced MaterialsJiangsu National Synergetic Innovation Centre for Advanced MaterialsNanjing University of Post and TelecommunicationsNanjing 210023China Laboratory of Molecular Imaging Department of RadiologyThe First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029China Department of Radiology The 909th HospitalSoutheast HospitalSchool of MedicineXiamen UniversityZhangzhou 363000China State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and EngineeringInstitute of Functional MaterialsDonghua UniversityShanghai 201620China

Photodynamic therapy(PDT)is an effective treatment method for *** the specifically accumulated of photosensitizer was very difficult in the tumor site,which greatly limited the efficacy of ***,mitochondria-targeted Janus mesoporous nanoplatform(JPMO-Pt-CTPP-ZnPc)for PDT was prepared,the nanoplatform has uniform size(275 nm)and good dispersion and *** confocal laser scanning microscopy(CLSM)revealed the signal of ZnPc of JPMO-Pt-CTPP-ZnPc were higher than JPMO-Pt-ZnPc in tumor cells,and flow cytometry results showed the cell uptake efficiency of JPMO-Pt-CTPP-ZnPc was 2.5-fold higher than that of *** revealed the modification of CTPP significantly improves the targeting ability of the *** vitro anti-tumor experiment showed the JPMO-Pt-CTPP-ZnPc significantly inhibited the growth of tumor cells upon the irradiation of low-power laser,and the survival rate of cells incubated with 60μg/mL JPMO-Pt-CTPP-ZnPc was only 3%.Simultaneously,compared with JPMO-Pt-ZnPc(not modified with mitochondria targeting molecules CTPP),the PDT efficacy of JPMO-Pt-CTPP-ZnPc was significantly better,as it has targeted mitochondria in cells.

关键词： Mesoporous materials Janus particle Photodynamic therapy Mitochondria targeting Tumor treatment

Expression and clinical significance of pattern recognition receptor-associated genes in hand, foot and mouth disease

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Asian Pacific Journal of Tropical Medicine 2024年第4期17卷 173-183,I0001-I0003页

作者： Muqi Wang Huiling Deng Yuan Chen Yikai Wang Yufeng Zhang Chenrui Liu Meng Zhang Ting Li Shuangsuo dang Yaping Li Department of Infectious Diseases The Second Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710004China Department of Pediatrics Xi'an Central HospitalXi'an 710004China Department of Infectious Diseases Xi'an Children's HospitalXi'an 710003China

Objective:To explore which pattern recognition receptors(PRRs)play a key role in the development of hand,foot,and mouth disease(HFMD)by analyzing PRR-associated ***:We conducted a comparative analysis of PRR-associated gene expression in human peripheral blood mononuclear cells(PBMCs)infected with enterovirus 71(EV-A71)which were derived from patients with HFMD of different severities and at different stages.A total of 30 PRR-associated genes were identified as significantly upregulated both over time and across different EV-A71 ***,ELISA was employed to quantify the expression of the six most prominent genes among these 30 identified genes,specifically,BST2,IRF7,IFI16,TRIM21,MX1,and ***:Compared with those at the recovery stage,the expression levels of BST2(P=0.027),IFI16(P=0.016),MX1(P=0.046)and DDX58(P=0.008)in the acute stage of infection were significantly upregulated,while no significant difference in the expression levels of IRF7(P=0.495)and TRIM21(P=0.071)was found between different stages of the *** expression levels of BST2,IRF7,IFI16 and MX1 were significantly higher in children infected with single pathogen than those infected with mixed pathogens,and BST2,IRF7,IFI16 and MX1 expression levels were significantly lower in coxsackie B virus(COXB)positive patients than the negative *** levels of one or more of BST2,IRF7,IFI16,TRIM21,MX1 and DDX58 genes were correlated with PCT levels,various white blood cell counts,and serum antibody levels that reflect disease course of *** aminotransferase was correlated with BST2,MX1 and DDX58 expression ***:PRR-associated genes likely initiate the immune response in patients at the acute stage of HFMD.

关键词： Pattern recognition receptors(PRRs) Hand,foot,and mouth disease(HFMD) Immune Enterovirus 71(EV-A71)

High-Al-composition AlGaN/GaN MISHEMT on Si with fT of 320 GHz

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Science China(Information Sciences) 2024年第6期67卷 459-460页

作者： Hanghai DU Lu HAO Zhihong LIU Zeyu SONG Yachao ZHANG Kui dang Jin ZHOU Jing NING Zan LI Jincheng ZHANG Yue HAO State Key Laboratory of Wide Bandgap Semiconductor Devices and Integrated Technology School of MicroelectronicsXidian University Guangzhou Wide Bandgap Semiconductor Innovation Center Guangzhou Institute of TechnologyXidian University State Key Laboratory of Integrated Services Networks School of Communication EngineeringXidian University

GaN-based metal-insulator-semiconductor high-electronmobility-transistors (MISHEMTs) have many excellent performances compared with the Si and Ga As counterparts,and are prime candidates for applications in communicat...

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CO_(2)升高和增温没有稀释椴树叶片氮浓度却降低了叶片的光合能力

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Journal of Plant Ecology 2024年第3期17卷 39-48页

作者： Lei Wang Jinping Zheng Gerong Wang Qing-Lai dang Department of Landscape Architechture Jiyang College of Zhejiang A&F UniversityZhuji 311800China Faculty of Natural Resources Management Lakehead UniversityThunder BayON P7B 5E1Canada Department of Forestry Forestry CollegeBeihua UniversityJilin 132013China

深入理解CO_(2)升高和全球变暖对植物的影响是预测植物适应性的关键。本研究以温带阔叶耐荫树种椴树(Tilia amurensis)幼苗为试验材料,研究了当前CO_(2)浓度和气温组合处理(CC)与预测的未来气候条件下CO_(2)升高和增温组合处理(FC)对植... 详细信息

深入理解CO_(2)升高和全球变暖对植物的影响是预测植物适应性的关键。本研究以温带阔叶耐荫树种椴树(Tilia amurensis)幼苗为试验材料,研究了当前CO_(2)浓度和气温组合处理(CC)与预测的未来气候条件下CO_(2)升高和增温组合处理(FC)对植物光合驯化的影响模式。结果发现,FC处理促进了椴树地上部分的生长,降低了叶片的光合能力(最大羧化速率和最大电子传递速率),也降低了椴树光合作用生化限制中从羧化限制向电子传递限制过渡点的光合速率。FC处理没有改变叶片氮浓度,但是提高了单株叶片的含氮量和光合氮素利用效率。这些结果表明,在椴树适应未来气候条件中发挥重要的作用的可能是叶片的氮素利用效率,而非其光合能力。本研究为理解椴树的光合驯化特征提供了新的见解,研究结果也可以用于预测椴树在未来气候条件下可能的表现。

关键词：椴树(Tilia amurensis) 光合驯化 CO_(2) 升高和增温温带阔叶树氮素浓度

Spatial transcriptomics:recent developments and insights in respiratory research

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Military Medical Research 2024年第3期11卷 430-448页

作者： Wen-Jia Wang Liu-Xi Chu Li-Yong He Ming-Jing Zhang Kai-Tong dang Chen Gao Qin-Yu Ge Zhou-Guang Wang Xiang-Wei Zhao State Key Laboratory of Bioelectronics School of Biological Science and Medical EngineeringSoutheast UniversityNanjing 210096China Oujiang Laboratory(Zhejiang Lab for Regenerative Medicine Vision and Brain Health)School of Pharmaceutical SciencesWenzhou Medical UniversityWenzhou 325035ZhejiangChina Orthopaedic Bioengineering Research Group Division of Surgery and Interventional ScienceUniversity College LondonLondon HA74LPUK

The respiratory system's complex cellular heterogeneity presents unique challenges to researchers in this *** bulk RNA sequencing and single-cell RNA sequencing(scRNA-seq)have provided insights into cell types and heterogeneity in the respiratory system,the relevant specific spatial localization and cellular interactions have not been clearly *** transcriptomics(ST)has filled this gap and has been widely used in respiratory *** review focuses on the latest iterative technology of ST in recent years,summarizing how ST can be applied to the physiological and pathological processes of the respiratory system,with emphasis on the ***,the current challenges and potential development directions are proposed,including high-throughput full-length transcriptome,integration of multi-omics,temporal and spatial omics,bioinformatics analysis,*** viewpoints are expected to advance the study of systematic mechanisms,including respiratory studies.

关键词： Spatial transcriptomics Lung Tumor Spatial multi-omics

A review on DFACS(II):Modeling and analysis of disturbances and noises

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Chinese Journal of Aeronautics 2024年第5期37卷 120-147页

作者： Chenglei YUE Bohan JIAO Zhaohui dang Xiaokui YUE Yonghe ZHANG Yuanqing XIA Li DUAN Qinglei HU Qifan LIU Pengcheng WANG Ming GUO Zhansheng DUAN Bing CUI Chu ZHANG Xiaodong SHAO School of Astronautics Northwestern Polytechnical UniversityXi’an 710072China Innovation Academy for Microsatellites Chinese Academy of SciencesShanghai 710699China School of Automation Beijing Institute of TechnologyBeijing 100081China Institute of Mechanics Chinese Academy of SciencesBeijing 710043China School of Automation Science and Electrical Engineering Beihang UniversityBeijing 100191China School of Automation Science and Engineering Xi’an Jiaotong UniversityXi’an 710049China

This paper presents Part II of a review on DFACS,which specifically focuses on the modeling and analysis of disturbances and noises in *** Part I,the system composition and dynamics model of the DFACS were *** this paper,we discuss the effects of disturbance forces and noises on the system,and summarize various analysis and modeling methods for these interferences,including the integral method,frequency domain analysis method,and magnitude evaluation *** analyzing the impact of disturbances and noises on the system,the paper also summarizes the system’s performance under slight ***,we highlight current research difficulties in the field of DFACS noise ***,this paper provides valuable insights into the modeling and analysis of disturbances and noises in DFACSs,and identifies key areas for future research.

关键词： Drag-free DFACS Disturbance Analysis Noise Analysis Frequency Domain Analysis Performance Evaluation

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多变量时滞阻尼累加灰色模型及其应用

控制与决策 2024年第8期39卷 2703-2710页

作者：罗党李良帅华北水利水电大学数学与统计学院郑州450046 华北水利水电大学水利学院郑州450046

基于现实行为系统中存在的时滞效应和多变量灰色预测系统中需区分新旧信息及预测趋势不可控的情况,通过引入改进的阻尼累加生成算子与时滞系数,提出多变量时滞阻尼累加灰色模型(TLDAGM(1,N))及其扩展形式,模型理论上可达到与传统多变量... 详细信息

基于现实行为系统中存在的时滞效应和多变量灰色预测系统中需区分新旧信息及预测趋势不可控的情况,通过引入改进的阻尼累加生成算子与时滞系数,提出多变量时滞阻尼累加灰色模型(TLDAGM(1,N))及其扩展形式,模型理论上可达到与传统多变量灰色预测模型的兼容性;讨论模型的参数估计方式及求解方法,给出模型的参数优化方法及具体的建模步骤;将该模型应用于我国高新技术企业产值及河南省粮食产量预测问题中,并与传统多变量灰色预测模型进行比较.结果表明:所提模型的模拟精度和预测精度均显著优于传统多变量灰色预测模型,新模型能够较好地识别多变量行为系统数据中包含的时滞性、重要性及时间序列的趋势因素.实例分析的结果验证了所提模型的合理性、适用性和有效性.

关键词：时滞效应灰色预测系统新旧信息阻尼累加生成算子粮食产量预测

A review on DFACS(I):System design and dynamics modeling

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Chinese Journal of Aeronautics 2024年第5期37卷 92-119页

作者： Bohan JIAO Qifan LIU Zhaohui dang Xiaokui YUE Yonghe ZHANG Yuanqing XIA Li DUAN Qinglei HU Chenglei YUE Pengcheng WANG Ming GUO Zhansheng DUAN Bing CUI Chu ZHANG Xiaodong SHAO School of Astronautics Northwestern Polytechnical UniversityXi’an 710072China Innovation Academy for Microsatellites Chinese Academy of SciencesShanghai 710699China School of Automation Beijing Institute of TechnologyBeijing 100081China Institute of Mechanics Chinese Academy of SciencesBeijing 710043China School of Automation Science and Electrical Engineering Beihang UniversityBeijing 100191China School of Automation Science and Engineering Xi’an Jiaotong UniversityXi’an 710049China

The Drag-Free and Attitude Control System(DFACS)is a critical platform for various space missions,including high precision satellite navigation,geoscience and gravity field measurement,and space scientific *** paper presents a comprehensive review of over sixty years of research on the design and dynamics model of ***,we examine the open literature on DFACS and its applications in Drag-Free missions,providing readers with necessary background information on the ***,we analyze the system configurations and main characteristics of different DFACSs,paying particular attention to the coupling mechanism between the system configuration and dynamics ***,we summarize the dynamics modeling methods and main dynamics models of DFACS from multiple perspectives,including common fundamentals and specific ***,we identify current challenges and technological difficulties in the system design and dynamics modeling of DFACS,while suggesting potential avenues for future *** paper aims to provide readers with a comprehensive understanding of the state-of-the-art in DFACS research,as well as the future prospects and challenges in this field.

关键词： Drag-Free DFACS System Design Dynamics Modeling Control design