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乳房穴位按摩配合袋鼠式护理在产妇产后的应用效果

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中西医结合护理（中英文） 2024年第3期10卷 49-52页

作者：陈燕敏洪彩香吴丹丹中国人民解放军陆军第七十三集团军医院福建厦门361001

目的产后给予产妇乳房穴位按摩配合袋鼠式护理,探讨对其纯母乳喂养率、泌乳量以及乳房胀痛情况的影响。方法选取2021年12月至2022年12月中国人民解放军陆军第七十三集团军医院产科病区的100名产妇为研究对象,以随机数字表法将其分为2组... 详细信息

目的产后给予产妇乳房穴位按摩配合袋鼠式护理,探讨对其纯母乳喂养率、泌乳量以及乳房胀痛情况的影响。方法选取2021年12月至2022年12月中国人民解放军陆军第七十三集团军医院产科病区的100名产妇为研究对象,以随机数字表法将其分为2组,即观察组(50名,给予产后乳房穴位按摩及袋鼠式护理)和对照组(50名,采用常规护理方式)。比较2组产妇的纯母乳喂养率、泌乳量及乳房疼痛情况,以及新生儿生长发育指标。结果观察组的产后纯母乳喂养率高于对照组(P<0.05);观察组产妇在护理7 d后的泌乳量优于对照组(P<0.05);观察组产妇在护理7 d后的视觉模拟评分法评分低于对照组(P<0.05);观察组新生儿的生长发育各项指标均优于对照组(P均<0.05)。结论在产妇产后护理中,给予其乳房穴位按摩及袋鼠式护理,可提高产妇产后的纯母乳喂养率及泌乳量,改善其乳房胀痛情况,且能够优化新生儿的生长发育指标。

关键词：产妇乳房穴位按摩袋鼠式护理纯母乳喂养率乳房胀痛情况

头颈部肿瘤放疗患者发生放射性口腔黏膜炎的相关影响因素分析

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浙江创伤外科 2024年第7期29卷 1224-1227页

作者：曹雪晴陈彦敏章丽芳周丹萍浙江省杭州市肿瘤医院杭州310002

目的研究头颈部肿瘤放疗患者发生放射性口腔黏膜炎的相关影响因素。方法对2020年10月至2023年10月杭州市肿瘤医院收治的130例头颈部肿瘤放疗患者的临床资料进行回顾性分析,以患者是否发生放射性口腔黏膜炎将其分为研究组(发生,n=110)和... 详细信息

目的研究头颈部肿瘤放疗患者发生放射性口腔黏膜炎的相关影响因素。方法对2020年10月至2023年10月杭州市肿瘤医院收治的130例头颈部肿瘤放疗患者的临床资料进行回顾性分析,以患者是否发生放射性口腔黏膜炎将其分为研究组(发生,n=110)和对照组(未发生,n=20),应用单因素χ^(2)检验和多因素Logistic回归分析法分析患者发生放射性口腔黏膜炎的影响因素。结果单因素分析结果显示,放射性口腔黏膜炎发生与吸烟史、诱导化疗、口腔卫生状况、应用口腔黏膜保护剂情况有关(P<0.05)。多因素Logistic回归分析结果显示,放射性口腔黏膜炎发生与诱导化疗、未使用黏膜保护剂、吸烟、口腔卫生差均有关,其是导致放射性口腔黏膜炎发生的独立危险因素(P<0.05)。结论头颈部肿瘤放疗患者发生放射性口腔黏膜炎的几率较高,其中诱导化疗、吸烟、未使用黏膜保护剂、口腔卫生差是影响其发生放射性口腔黏膜炎的独立危险因素,因此在临床工作中可针对性预防以降低放射性口腔黏膜炎发生风险。

关键词：头颈部肿瘤放射性口腔黏膜炎放射疗法恶性肿瘤影响因素

分步消解法ICP-MS测量大米中砷及不确定度评价

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食品工业 2024年第1期45卷 304-308页

作者：卢鑫刘聪陈燕敏刘冰侯金妹郑州师范学院化学化工学院郑州450044 安徽泽众安全科技有限公司合肥232000 清华大学合肥公共安全研究院合肥230601

为提高食品中重金属测定方法的准确性与可重复性、保障人民食品安全,采用石墨-微波分步消解法,使用电感耦合等离子质谱(ICP-MS)对大米中重金属砷含量进行检测,并根据试验过程对检测结果进行不确定度评定,分析测量过程中的样品称量、样... 详细信息

为提高食品中重金属测定方法的准确性与可重复性、保障人民食品安全,采用石墨-微波分步消解法,使用电感耦合等离子质谱(ICP-MS)对大米中重金属砷含量进行检测,并根据试验过程对检测结果进行不确定度评定,分析测量过程中的样品称量、样品消解、标准溶液的配制、标准曲线的拟合和测量重复性等因素造成的不确定度,计算各不确定度分量,分析不确定度和扩展不确定度判断检测结果的可靠性。所测大米样品中的砷含量为0.110 mg/kg,扩展不确定度为0.011 mg/kg,k=2。通过对测量过程中不确定度的评定,试验发现该检测过程中的不确定度主要来源于样品消解和测量重复性,并与其他方法测试所得不确定度进行对比分析,结果较好。

关键词：分步消解大米砷不确定度

Response of ecosystem carbon storage to land use change from 1985 to 2050 in the Ningxia Section of Yellow River Basin,China

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Journal of Arid Land 2024年第1期16卷 110-130页

作者： LIN yanmin HU Zhirui LI Wenhui chen Haonan WANG Fang NAN Xiongxiong YANG Xuelong ZHANG Wenjun College of Geographical Sciences and Planning Ningxia UniversityYinchuan 750021China China-Arab Joint International Research Laboratory for Featured Resources and Environmental Governance in Arid Region Yinchuan 750021China Ningxia Land Resources Surveying and Monitoring Institute Yinchuan 750002China State Key Laboratory of Efficient Production of Forest Resources Yinchuan 750002China Ningxia Lingwu Baijitan National Nature Reserve Administration Yinchuan 751400China

Regional sustainable development necessitates a holistic understanding of spatiotemporal variations in ecosystem carbon storage(ECS),particularly in ecologically sensitive areas with arid and semi-arid *** this study,we calculated the ECS in the Ningxia Section of Yellow River Basin,China from 1985 to 2020 using the Integrated Valuation of Ecosystem Services and Tradeoffs(InVEST)model based on land use *** further predicted the spatial distribution of ECS in 2050 under four land use scenarios:natural development scenario(NDS),ecological protection scenario(EPS),cultivated land protection scenario(CPS),and urban development scenario(UDS)using the patch-generating land use simulation(PLUS)model,and quantified the influences of natural and human factors on the spatial differentiation of ECS using the geographical detector(Geodetector).Results showed that the total ECS of the study area initially increased from 1985 until reaching a peak at 402.36×10^(6) t in 2010,followed by a decreasing trend to *** spatial distribution of ECS was characterized by high values in the eastern and southern parts of the study area,and low values in the western and northern *** 1985 and 2020,land use changes occurred mainly through the expansion of cultivated land,woodland,and construction land at the expense of unused *** total ECS in 2050 under different land use scenarios(ranked as EPS>CPS>NDS>UDS)would be lower than that in *** light was the largest contributor to the spatial differentiation of ECS,with soil type and annual mean temperature being the major natural driving *** of this study could provide guidance on the ecological construction and high-quality development in arid and semi-arid areas.

关键词： carbon storage land use change nighttime light Integrated Valuation of Ecosystem Services and Tradeoffs(InVEST)model patch-generating land use simulation(PLUS)model geographical detector(Geodetector) Yellow River Basin

Urban growth scenario projection using heuristic cellular automata in arid areas considering the drought impact

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Journal of Arid Land 2024年第4期16卷 580-601页

作者： TANG Xiaoyan FENG Yongjiu LEI Zhenkun chen Shurui WANG Jiafeng WANG Rong TANG Panli WANG Mian JIN yanmin TONG Xiaohua College of Surveying&Geo-Informatics Tongji UniversityShanghai 200092China Shanghai Key Laboratory of Space Mapping and Remote Sensing for Planetary Exploration Tongji UniversityShanghai 200092China

Arid areas with low precipitation and sparse vegetation typically yield compact urban pattern,and drought directly impacts urban site selection,growth processes,and future *** simulation and projection based on cellular automata(CA)models is important to achieve sustainable urban development in arid *** developed a new CA model using bat algorithm(BA)named bat algorithm-probability-of-occurrence-cellular automata(BA-POO-CA)model by considering drought constraint to accurately delineate urban growth patterns and project future scenarios of Urumqi City and its surrounding areas,located in Xinjiang Uygur Autonomous Region,*** calibrated the BA-POO-CA model for the drought-prone study area with 2000 and 2010 data and validated the model with 2010 and 2020 data,and finally projected its urban scenarios in *** results showed that BA-POO-CA model yielded overall accuracy of 97.70%and figure-of-merits(FOMs)of 35.50%in 2010,and 97.70%and 26.70%in 2020,*** inclusion of drought intensity factor improved the performance of BA-POO-CA model in terms of FOMs,with increases of 5.50%in 2010 and 7.90%in 2020 than the model excluding drought intensity *** suggested that the urban growth of Urumqi City was affected by drought,and therefore taking drought intensity factor into account would contribute to simulation *** BA-POO-CA model including drought intensity factor was used to project two possible scenarios(i.e.,business-as-usual(BAU)scenario and ecological scenario)in *** the BAU scenario,the urban growth dominated mainly in urban fringe areas,especially in the northern part of Toutunhe District,Xinshi District,and Midong *** exceptional and extreme drought areas as a spatial constraint,the urban growth was mainly concentrated in the"main urban areas-Changji-Hutubi"corridor urban pattern in the ecological *** results of this research can help to adjust urban planning and development *** mode

关键词： bat algorithm cellular automata(CA) probability-of-occurrence drought intensity algorithm-probability-of-occurrence-cellular automata(BA-POO-CA)model arid areas

AUTOMATIC TEXT SUMMARIZATION BASED ON TEXTUAL COHESION

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Journal of Electronics(China) 2007年第3期24卷 338-346页

作者： chen yanmin Liu Bingquan Wang Xiaolong Dept of Computer Science and Engineering Harbin Institute of Technology Harbin 150001 China

This paper presents two different algorithms that derive the cohesion structure in the form of lexical chains from two kinds of language resources HowNet and TongYiCiCiLin. The re-search that connects the cohesion structure of a text to the derivation of its summary is displayed. A novel model of automatic text summarization is devised,based on the data provided by lexical chains from original texts. Moreover,the construction rules of lexical chains are modified accord-ing to characteristics of the knowledge database in order to be more suitable for Chinese summa-rization. Evaluation results show that high quality indicative summaries are produced from Chi-nese texts.

关键词：文本自动摘要织构内聚力词汇链

Pyrimethamine upregulates BNIP3 to interfere SNARE-mediated autophagosome-lysosomal fusion in hepatocellular carcinoma

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Journal of Pharmaceutical Analysis 2024年第2期14卷 211-224页

作者： Jingjing Wang Qi Su Kun chen Qing Wu Jiayan Ren Wenjuan Tang Yu Hu Zeren Zhu cheng cheng Kaihui Tu Huaizhen He yanmin Zhang School of Pharmacy Health Science CenterXi'an Jiaotong UniversityXi'an710061China

Hepatocellular carcinoma (HCC) is one of the most common tumor types and remains a major clinical challenge. Increasing evidence has revealed that mitophagy inhibitors can enhance the effect of chemotherapy on HCC. However, few mitophagy inhibitors have been approved for clinical use in humans. Pyrimethamine (Pyr) is used to treat infections caused by protozoan parasites. Recent studies have reported that Pyr may be beneficial in the treatment of various tumors. However, its mechanism of action is still not clearly defined. Here, we found that blocking mitophagy sensitized cells to Pyr-induced apoptosis. Mechanistically, Pyr potently induced the accumulation of autophagosomes by inhibiting autophagosome-lysosome fusion in human HCC cells. In vitro and in vivo studies revealed that Pyr blocked autophagosome-lysosome fusion by upregulating BNIP3 to inhibit synaptosomal-associated protein 29 (SNAP29)-vesicle-associated membrane protein 8 (VAMP8) interaction. Moreover, Pyr acted synergistically with sorafenib (Sora) to induce apoptosis and inhibit HCC proliferation in vitro and in vivo. Pyr enhances the sensitivity of HCC cells to Sora, a common chemotherapeutic, by inhibiting mitophagy. Thus, these results provide new insights into the mechanism of action of Pyr and imply that Pyr could potentially be further developed as a novel mitophagy inhibitor. Notably, Pyr and Sora combination therapy could be a promising treatment for malignant HCC.

关键词： Pyrimethamine BNIP3 SNARE Autophagosome-lysosome fusion Hepatocellular carcinoma Sorafenib

Changes of free radicals and digestive enzymes in saliva in cases with deficiency inspleen-yin syndrome

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The Journal of Biomedical Research 2010年第3期24卷 250-255页

作者： Muxin Wei yanmin Wu Dezheng chen Yuchun Gu Department of Traditional Chinese Medicine the First Affiliated Hospital with Nanjing Medical University Nanjing 210029 Jingsu Province China

Objective：To explore the nature of deficiency in spleen-yin syndrome,which could provide scientific theoretical support and practical guidance for clinical Traditional Chinese Medicine（TCM）syndrome differentiation based on biology,and had a strong clinical ***：Serum Cu and Zn were detected by atomic absorption spectrophotometer,serum vitamin E by high performance liquid chromatography,serum vitamin C by 2,4-Dinitrophenylhydrazine Colorimetry,total superoxide dismutase（SOD）and Cu and Zn- SOD by the xanthine oxidase method,and malondialdehyde（MDA）by the 2-thiobarbituric acid method（TBA）.Total antioxidant capacity was detected by a colorimetry *** Activity was detected by an automatic biochemical *** was detected by lysozyme detection plate,the diameter of bacteriolysis circle was measured and the corresponding content of lysozyme was obtained from a table of standard curve ***： No significant difference in total SOD and Cu,Zn-SOD was found between deficiency in spleen-yin group and normal ***,such factors in deficiency in kidney-yin group were significantly lower than the other groups（P〈0.05）.The MDA content in both deficiency in spleen-yin group and deficiency in kidney-yin group were significantly higher than that of normal group（P〈0.05）,while the total antioxidant capacity was significantly lower than normal group（P〈0.05）.The vitamin E content in deficiency in kidney-yin group was significantly lower than that in the other two groups（P〈0.05）.No significant difference in the contents of vitamin C,Cu and Zn were observed in these *** Zn/Cu level in deficiency in kidney-yin group and the vitamin E level in deficiency in spleen-yin group decreased,but with no significant *** activity in unit time in cases with deficiency in spleen-yin was lower than and had significant differences with that in normal cases,and higher than that in cases with deficiency in *** sectional velocity

关键词： deficiency in spleen-yin deficiency in kidney-yin digestive enzymes in saliva amylase salivary lysozyme salivary flow rate free radicals

Metagenomics analysis identifies oral Streptococcus as potential biomarkers for nasopharyngeal carcinoma

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Journal of Genetics and Genomics 2024年第3期51卷 363-366页

作者： yanmin Liu chengtao Wang Lixiang Xie Shuling Du Li Ding Ying Cui Runzhi chen Jingxiang Zhang Wan Wang Xi Liu Yan Wang Shiyan chen Tian Tan Qiaochu Zhao Limei Yin Chunwei Li Yong chen Tao Ding Department of Immunology and Microbiology Zhongshan School of MedicineSun Yat-sen UniversityGuangzhouGuangdong 510080China Key Laboratory of Tropical Disease Control(Sun Yat-sen University) Ministry of EducationGuangzhouGuangdong 510080China Department of Radiation Oncology The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong 510080China Department of Infectious Diseases The Fifth Affiliated HospitalSun Yat-sen UniversityZhuhaiGuangdong 519000China Department of Endocrinology&Metabolism The Fifth Affiliated HospitalSun Yat-sen UniversityZhuhaiGuangdong 519000China Department of Otolaryngology The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong 510080China

Nasopharyngeal carcinoma(NPC)is a malignancy originating from the nasopharyngeal epithelial *** some studies have identified potential biomarkers for early diagnosis of NPC based on metabolomics data(chen et al.,2023;Zhou et al.,2023)and Epstein-Barr virus subtypes(Xu et al.,2019),their effectiveness and applicability need further investigation,particularly when consideringthe roles of oral microbiota.

关键词： al. nasopharyngeal diagnosis