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An AIEE polyelectrolyte as a light-up fluorescent probe for heparin sensing in full detection range

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Science China Chemistry 2013年第9期56卷 1239-1246页

作者： CHEN DongYang SHI JianBing wu yanmei TONG Bin ZHI JunGe DONG YuPing School of Materials Science and Engineering Beijing Institute of Technology School of Chemistry Beijing Institute of Technology

Polyelectrolyte PTPEPyH, containing tetraphenylethene (TPE) and pyridinium, was synthesized. Its optical properties were investigated with spectroscopies and the results showed that there were two emission-enhanced stages in the interaction between positive-charged PTPEPyH and negative-charged biomacromolecule heparin. The mechanism was very different due to the reduced non-radiative energy loss and the change of surroundings. The polyelectrolyte PTPEPyH, compared with ChS and HA, also showed high selectivity for heparin in the buffer solution and could be used as a potential bio-probe for heparin quantification in the clinical full range.

关键词： aggregation-induced emission enhancement (AIEE) tetraphenylethene (TPE) heparin quantification pyridinium biosensor

A Study on the Impact of Psychological Counseling for Minor Medical Students in Clinical Teaching and Learning

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Journal of Clinical and Nursing Research 2024年第7期8卷 334-341页

作者： Xiaorong Fan yanmei wu Qianwei People’s Hospital Leshan 614400Sichuan ProvinceChina

Objective:To explore the impact of psychological counseling for underage medical students in clinical ***:24 of the 48 underage medical students who were interned in our hospital from March 2023 to February 2024 were randomly selected to adopt the teaching management method of one-on-one psychological guidance as the observation group;the remaining 24 adopted the traditional teaching management method as the control *** observation of the effects of psychological detachment on various aspects of underage medical students allows the determination of whether psychological detachment impacts clinical ***:The observation group’s theoretical examination scores,skill assessment scores,and departmental performance evaluation scale score excellence rate were higher than the control group’s,with P<0.05 being statistically *** the same time,the clinical teaching and teaching management ability of the hospital was also ***:Psychological guidance for underage medical students can not only improve the comprehensive quality of medical students but also improve the teaching level,which is conducive to improving the teaching effect,and it is a clinical teaching mode worth promoting.

关键词： Psychological counseling Underage medical students Clinical teaching

Reformation Professional academies Information literacy Education Promotion High-quality Information Military Talent Training

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Reformation Professional academies Information literacy Educ...

Correlation of Inflammatory Cells in Induced Sputum and Peripheral Blood of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

2013教育技术与信息系统国际会议

作者： wu yanmei PENG Zhijun WEN Xingwang Academy of Equipment Kunming University of Science & Technology

Information literacy is the essential quality for the military talents, and is the concentrated expression of the comprehensive quality of military talents. In this paper, the connotation of the information literacy is explained. And the reform measures are also proposed from reforming information literacy training system, optimizing information technology teaching environment, exercising capacity for scientific research, expanding education and training channels to promote information literacy education.

关键词： Professional Education Information Literacy Culture

来源： cnki会议评论

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Open Journal of Respiratory Diseases 2021年第3期11卷 105-115页

作者： Xin Wang Di wu yanmei wu Hongyan Liu Ying Wang Chunmei Yun Dejun Sun Xiaoyu Gao Key Laboratory of National Health Commission for the Diagnosis & Treatment of COPD Inner Mongolia Key Laboratory of Respira-tory Diseases Inner Mongolia People’s Hospital Hohhot China Department of Geriatric Medicine Inner Mongolia People’s Hospital Hohhot China Department of Respiratory and Critical Care Medicine Inner Mongolia People’s Hospital Hohhot China

Chronic obstructive pulmonary disease (COPD) is a major chronic respiratory disease worldwide. Inflammatory cells reflect the inflammatory situation both in peripheral blood and induced sputum. Their correlation has not been reported. The correlation between neutrophils (Neu), eosinophils (Eos), and lymphocyte (Lym) in induced sputum and that in peripheral blood of COPD patients was evaluated to explore the consistency of inflammatory cells in peripheral blood and induced sputum. Peripheral blood and induced sputum were collected from 437 patients with acute exacerbation of COPD (AECOPD) who were hospitalized in the Department of respiratory and critical care medicine, Inner Mongolia People’s Hospital. The correlation analysis was performed by Spearman correlation analysis. The ratios of Neu, Eos, and Lym in induced sputum were (79.15 ± 22.60)%, (5.23 ± 12.74)%, and (1.69 ± 2.66)%. The ratios of Neu, Eos, and Lym in peripheral blood were (63.29 ± 11.44)%, (2.99 ± 3.60)%, and (25.16 ± 10.19)%. The results showed that the ratios of Neu and Eos in induced sputum were significantly correlated with the proportion of corresponding cells in peripheral blood (P There was no correlation between the ratio of Lym and Leu in induced sp

关键词： Chronic Obstructive Pulmonary Disease Induced Sputum Peripheral Blood Inflammatory Cells

Phytoplankton Structure and Evaluation of Water Quality in Spring in the Moats of Dinghai District,Zhoushan City

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Meteorological and Environmental Research 2016年第6期7卷 58-61页

作者： wu yanmei wu Jiameng Hu Fanglu Dai Jiawei Zhang Shaoqiu Zhang Wenjun Zhu Mingdong Xu Nana Zhejiang Ocean University Zhoushan 316021 China Ocean Research Center of Zhoushan Zhejiang University Zhoushan 316022 China

Phytoplankton structure in spring in the moats of Dinghai District,Zhoushan City was investigated in April 2016. Firstly,the species composition and dominant species of phytoplankton were analyzed,and then the water quality of the moats was evaluated by cell density,water-quality indicator species,biodiversity index method,and saprobic index method. The results show that there were 114 species of phytoplankton in the moats of Dinghai District in spring,belonging to 70 genera,38 families,and 7 phyla,of which Bacillarophyta,Chlorophyta and Cyanophyta were dominant; the main dominant species were Synedra acus,Aphanizomenon flosaquae,Microcytis flos-aquae,etc. The cell density of phytoplankton in the moats ranged from 1.07 million to 13.7 million cells/L. Shannon-Wiener diversity index,Margalef richness index,Pielou evenness index,and saprobic index averaged 0.93,2.53,0.12,and 2.61 respectively. On the whole,river water in the moats of Dinghai District was polluted seriously,but there was no obvious difference between the four rivers in water pollution.

关键词： Moats of Dinghai District Phytoplankton Biological assessment Biodiversity index China

叙事学视域下中华民族共同体意识在统编语文教材中建构的内涵与理路

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课程．教材．教法 2024年第6期44卷 101-108页

作者：吴艳梅张旭河北师范大学初等教育系石家庄050024 河北师范大学教育学院石家庄050024

统编语文教材是中小学铸牢中华民族共同体意识教育的重要载体。中华民族共同体意识在教材中的建构强调引导学生坚定五个认同,增进共同性是建构的基础和方向。教材采用语言与非语言相结合的叙述方式,叙述中华民族共同体“四个共同”的故... 详细信息

统编语文教材是中小学铸牢中华民族共同体意识教育的重要载体。中华民族共同体意识在教材中的建构强调引导学生坚定五个认同,增进共同性是建构的基础和方向。教材采用语言与非语言相结合的叙述方式,叙述中华民族共同体“四个共同”的故事,以构成教材的核心内容。“人文主题”加“语文要素”的主题单元叙事结构展现中华民族共同体故事脉络,并以多模态呈现中华优秀传统文化、革命文化、社会主义先进文化等中华民族共同体符号。此外,统编语文教材中学习支架的搭建,体现了对学生主体地位的观照,助力学生铸牢中华民族共同体意识。

关键词：统编语文教材中华民族共同体意识共同性叙事学

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南海西北与西南次海盆沉积通量及其控制因素

地球科学 2021年第3期46卷 986-1007页

作者：王菲吴艳梅丁巍伟上海交通大学海洋学院上海200030 自然资源部海底科学重点实验室自然资源部第二海洋研究所浙江杭州310012 浙江大学地球科学学院浙江杭州310027

作为西太平洋陆源沉积"源-汇"过程的重要场所,南海海盆半封闭的构造环境使得其与开放大洋的物质交换十分有限,沉积物保存基本完整,可以建立起南海沉积过程与区域重大构造事件、气候变化、海平面变化等之间的系统联系.选取南海西南与西... 详细信息

作为西太平洋陆源沉积"源-汇"过程的重要场所,南海海盆半封闭的构造环境使得其与开放大洋的物质交换十分有限,沉积物保存基本完整,可以建立起南海沉积过程与区域重大构造事件、气候变化、海平面变化等之间的系统联系.选取南海西南与西北两个次海盆为对比研究区,基于穿越海盆的高分辨率多道地震测线和国际大洋发现计划(International Ocean Discovery Program,简称IODP)在南海获取的钻井数据,井震结合划分沉积单元,计算不同地质历史时期沉积通量,从而对海盆的沉积过程进行半定量化约束,并对控制因素和可能物源进行探讨.结果表明:南海西北次海盆和西南次海盆深海盆区的沉积过程整体上受到大型构造事件(青藏高原隆升-剥蚀作用)、东亚季风演化、陆缘水系(珠江、湄公河等)发展和相对海平面变化的控制,但在不同的区域会由于所处地理位置不同,以及局部构造事件影响而变得复杂化,从而使得西北次海盆与西南次海盆沉积通量在相同的地质时期呈现出不同的特征.西北次海盆沉积物主要源自华南大陆,并有少量来自红河、海南岛、北部陆架区局部隆起(如东沙隆起)的贡献.而西南次海盆的沉积物在晚中新世之前主要来自印支半岛、南沙地区和巴拉望,而在之后主要来自于现代湄公河.

关键词： IODP 多道地震数据沉积通量南海海盆控制因素海洋地质

An AIEE polyelectrolyte as a light-up fluorescent probe for heparin sensing in full detection range

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中国科学：化学 2013年第9期43卷 1213-1213页

作者： CHEN DongYang SHI JianBing wu yanmei TONG Bin ZHI JunGe DONG YuPing School of Materials Science and Engineering Beijing Institute of Technology Beijing 100081 China School of Chemistry Beijing Institute of Technology Beijing 100081 China

Polyelectrolyte PTPEPyH,containing tetraphenylethene(TPE)and pyridinium,was *** optical properties were investigated with spectroscopies and the results showed that there were two emission-enhanced stages in the interaction between positive-charged PTPEPyH and negative-charged biomacromolecule *** mechanism was very different due to the reduced non-radiative energy loss and the change of *** polyelectrolyte PTPEPyH,compared with ChS and HA,also showed high selectivity for heparin in the buffer solution and could be used as a potential bio-probe for heparin quantification in the clinical full range.

关键词：聚电解质肝素检测范围荧光探针传感生物大分子硫酸软骨素光学特性

Efficacy and safety of the combination of Liushen capsules and Arbidol in the treatment of COVID-19:protocol for a randomized,multi-center pilot study

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TMR Modern Herbal Medicine 2020年第4期3卷 202-208页

作者： Yangqing Zhan Zhengtu Li Jiayang He Shaoqiang Li Ye Lin Jingyi Liang Jie Zhou yanmei wu Xuandan Su Feng Ye Zifeng Yang National Clinical Research Center for Respiratory Disease Guangzhou Institute of Respiratory HealthFirst Affiliated Hospital of Guangzhou Medical UniversityState Key Laboratory of Respiratory Disease(Guangzhou Medical University)Guangzhou 510230China Guang Zhou Evidence-Based Medicine Technology Co. LtdGuangzhou 510000China Macao Institute for Applied Research in Medicine and Health State Key Laboratory of Quality Research in Chinese MedicineMacao University of Science and TechnologyMacao999078China

Background:From early experience,some Traditional Chinese Medicine and Arbidol had effects of against COVID-19,infer that the combination of Liushen capsules and Arbidol may further increase the ***/Design:We conducted a randomized,blank parallel-controlled,open-label,multi-center,basal therapy-loaded design clinical trial.A total of 40 patients are going to be recruited after satisfying the *** will be allocated randomly into the treatment group with the combination of Arbidol and Liushen capsules and the control group with the basic *** group will receive treatment at least 7-days or until the virus becomes negative,and visits after drug administration at day 3(visit 1),the day when the virus becomes negative(visit 2),day 7(visit 3),the day before discharge(visit 4)and day 28(visit 5),to collect their survival status and disease prognosis so that the efficacy and safety of a combination of Arbidol and Liushen capsule will be ***:We described the protocol of the first clinical trial for treatment COVID-19 by using a combination of Arbidol and Liushen *** results of this study will provide a basis for the design and sample size estimate of subsequent large-scale clinical *** registration:This study has been registered at Chinese clinical trial Registry(***):ChiCTR2000029993.

关键词： Arbidol Liushen capsules COVID-19 Clinical trial