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Recent progress in flexible and wearable bio-electronics based on nanomaterials

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Nano Research 2017年第5期10卷 1560-1583页

作者： Yanbing yang Xiangdong yang yaning Tan Quan Yuan Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education) College of Chemistry and Molecular SciencesWuhan University Wuhan 430072 China

Flexible and stretchable biosensors that can monitor and quantify the electrical or chemical signals generated by specific microenvironments have attracted a great deal of attention. Wearable biosensors that can be intimately attached to skin or tissue provide a new opportunity for medical diagnostics and therapy. In recent years, there has been enormous progress in device integration and the design of materials and manufacturing processes for flexible and stretchable systems. Here, we describe the most recent developments in nanomaterials employed in flexible and stretchable biosensors. We review successful examples of such biosensors used for the detection of vital physiological and biological markers such as gas released from organisms. Furthermore, we provide a detailed overview of recent achievements regarding integrated platforms that include multifunctional nanomaterials. The issues and challenges related to the effective integration of multifunctional nanomaterials in bio-electronics are also discussed.

关键词： flexible biosensor electronics nanostructured materials integrated devices graphene

姜黄素对热应激状态下波槐杂交羊生长性能和血液生化指标的影响

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中国饲料 2024年第18期 33-36页

作者：杨艳玲张福寿李改英商丘职业技术学院河南商丘476100 河南农业大学动物科技学院河南郑州450046

本研究旨在评价不同添加剂量的姜黄素对热应激条件下波槐杂交羊生长性能及血液生化指标的影响。试验将30头体重为(28.03±0.32)kg的健康波槐杂交公羊随机分为3组,每组10只,分别饲喂0 mg/头/d(CON组)、450 mg/头/d(CUL组)、900 mg/头/d(... 详细信息

本研究旨在评价不同添加剂量的姜黄素对热应激条件下波槐杂交羊生长性能及血液生化指标的影响。试验将30头体重为(28.03±0.32)kg的健康波槐杂交公羊随机分为3组,每组10只,分别饲喂0 mg/头/d(CON组)、450 mg/头/d(CUL组)、900 mg/头/d(CUH组)的姜黄素,预饲期15 d,正试期60 d。结果显示:(1)CUL组波槐杂交羊的平均日增重和总增重显著高于CON和CUH组(P<0.05)。(2)CUL组波槐杂交羊血清中的总蛋白和球蛋白含量显著高于CON和CUH组(P<0.05)。(3)CUL组杂交羊血清中的免疫球蛋白G含量显著高于CON和CUH组(P<0.05),CON和CUH组杂交羊血清中的丙二醛含量显著高于CUL组(P<0.05)。综上所述,日粮中添加450 mg/头/d的姜黄素可以改善热应激条件下波槐杂交羊的应激状态和健康状态,并进一步提高生长性能。

关键词：姜黄素波槐杂交羊热应激生长性能血液指标

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基于卷积神经网络的玉米种子质量检测

大连民族大学学报 2024年第1期26卷 62-67页

作者：刘琳茜杨亚宁大连民族大学信息与通信工程学院辽宁大连116605

为提高玉米种子质量检测的精准率,以不同质量的单颗玉米种子为研究对象,提出一种基于卷积神经网络的玉米种子质量检测方法。通过旋转、镜像、明暗变换、添加噪声等方法对现有数据集进行扩充;利用调整对比度和Blob分析方法增强图像特征;... 详细信息

为提高玉米种子质量检测的精准率,以不同质量的单颗玉米种子为研究对象,提出一种基于卷积神经网络的玉米种子质量检测方法。通过旋转、镜像、明暗变换、添加噪声等方法对现有数据集进行扩充;利用调整对比度和Blob分析方法增强图像特征;选用卷积神经网络(CNN)的Resnet50分类模型与Squeezenet模型分别进行试验,将数据集按不同的比例分组,通过训练实现玉米种子按照好、坏、杂质的分类检测。最终对六组实验的综合评价指标对比得出:数据集按9:1的训练测试比例分配,选用Resnet50模型训练效果最好,平均综合指标达到96.45%。

关键词：缺陷检测玉米种子数据增强卷积神经网络

Correcting for biases in affected sib-pair linkage analysis caused by uncertainty in sibling relationship

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Science China Mathematics 2012年第6期55卷 1127-1135页

作者： YUAN Min CUI WenQuan yang yaning School of Mathematics University of Science and Technology of ChinaHefei 230026China Department of Statistics and Finance University of Science and Technology of ChinaHefei 230026China

When there is uncertainty in sibling relationship,the classical affected sib-pair(ASP) linkage tests may be severely *** can happen,for example,if some of the half sib-pairs are mixed with full *** genomic control method has been used in association analysis to adjust for population *** show that the same idea can be applied to ASP linkage analysis with uncertainty in sibling *** that,in addition to the candidate marker,null markers that are unlinked to the disease locus are also genotyped,we may use the information on these loci to estimate the proportion of half sib-pairs and to correct for the bias and variance distortion caused by the heterogeneity of sibling *** in association studies,the null loci are not required to be matched with the candidate marker in allele frequency for ASP linkage *** makes our approach flexible in selecting null *** our simulations,using a number of 30 or more null loci can effectively remove the bias and variance *** is also shown that,even the null loci are weakly linked to the disease locus,the proposed method can also provide satisfactory correction.

关键词： affected sib-pairs bias null marker half sib-pairs variance distortion identical-by-descent (IBD)

Random weighting method for Cox’s proportional hazards model

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Science China Mathematics 2008年第10期51卷 1843-1854页

作者： CUI WenQuan LI Kai yang yaning WU YueHua Department of Statistics and Finance University of Science and Technology of ChinaHefei 230026China Department of Mathematics and Statistics York UniversityTorontoOntario M3J 1P3Canada

Variance of parameter estimate in Cox’s proportional hazards model is based on asymptotic variance. When sample size is small, variance can be estimated by bootstrap method. However, if censoring rate in a survival data set is high, bootstrap method may fail to work properly. This is because bootstrap samples may be even more heavily censored due to repeated sampling of the censored observations. This paper proposes a random weighting method for variance estimation and confidence interval estimation for proportional hazards model. This method, unlike the bootstrap method, does not lead to more severe censoring than the original sample does. Its large sample properties are studied and the consistency and asymptotic normality are proved under mild conditions. Simulation studies show that the random weighting method is not as sensitive to heavy censoring as bootstrap method is and can produce good variance estimates or confidence intervals.

关键词： bootstrap Cox model censoring rate random weighting consistency asymptotic normality 62N01 62N02 62N03 62F40 62G09

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概率论中的幂律分布

曲阜师范大学学报（自然科学版） 2024年第3期50卷 117-122页

作者：袁敏李洁雪庄玮玮杨亚宁安徽医科大学卫生管理学院 230032 中国科学技术大学管理学院安徽省合肥市230026

幂律分布用于描述个体相互影响的复杂系统中的数量分布规律,是概率论与数理统计学中最重要的分布之一,然而在教学中甚少对其进行详细的介绍.该文将详细讨论幂律分布的定义及性质、常见的幂律分布以及幂律分布的应用,并结合具体实例通过... 详细信息

幂律分布用于描述个体相互影响的复杂系统中的数量分布规律,是概率论与数理统计学中最重要的分布之一,然而在教学中甚少对其进行详细的介绍.该文将详细讨论幂律分布的定义及性质、常见的幂律分布以及幂律分布的应用,并结合具体实例通过R软件进行数据分析,给出相关教学内容和教学方法的若干建议.

关键词：幂律分布齐夫定律异速生长克莱伯定律无标度社交网络帕累托分布

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Recent advances on the construction of encapsulated catalyst for catalytic applications

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Nano Research 2023年第2期16卷 3451-3474页

作者： Minghui Li yaning yang Dailiang Yu Wenwen Li Xin Ning Rui Wan Hongjie Zhu Junjie Mao School of Ecology and Environment Anhui Normal UniversityWuhu 241002China Key Laboratory of Functional Molecular Solids Ministry of EducationCollege of Chemistry and Materials ScienceAnhui Normal UniversityWuhu 241002China College of Environmental Science and Engineering Yangzhou UniversityYangzhou 225127China Shandong Provincial Key Laboratory of Chemical Energy Storage and Novel Cell Technology School of Chemistry and Chemical EngineeringLiaocheng UniversityLiaocheng 252059China

In heterogeneous catalytic reactions,supported metal catalysts have attracted increasing attention for the environmental remediation and industrial manufacture due to their inherent catalytic ***,leaching,agglomeration,and poisoning of active metal particles lead to catalyst deactivation,thereby limiting their *** avoid this,strategies to protect the active metals from such inactivating processes are major areas of *** encapsulation strategies,in which active species are coated by protective shells,have proven to be a powerful technology to enhance catalytic performance by creating a well-developed structure about the active catalytic *** review highlights the recent advances on preparation method and application of encapsulated catalysts since *** upon the traditional confinement effect,new categories and extended concepts of encapsulation are *** parallel,effects of encapsulation structure on performance and key factors controlling the structure of encapsulated catalyst are discussed definitely in this ***,future perspectives on opportunities and challenges for further research in the field are given at the end of this paper.

关键词： heterogeneous catalysis encapsulated catalyst catalyst design deactivation catalytic performance

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庆阳市西峰区耕地质量等级评价

寒旱农业科学 2024年第9期3卷 852-858页

作者：张鹏祥杨子凡火克旺杨亚宁汪睿庆阳市农业技术推广中心甘肃庆阳745000 甘肃智慧科学技术服务有限公司甘肃庆阳745000 庆阳市西峰区农业技术推广中心甘肃庆阳745000

为了科学开展耕地质量保护和提升,掌握耕地质量等级现状,明确中低产田分布状态,以庆阳市西峰区2021年44个耕地质量调查监测点为研究对象,各监测点从耕层土壤理化性状、剖面构型、土壤养分、田间管理5个层面搜集获取16个评价指标数据,通... 详细信息

为了科学开展耕地质量保护和提升,掌握耕地质量等级现状,明确中低产田分布状态,以庆阳市西峰区2021年44个耕地质量调查监测点为研究对象,各监测点从耕层土壤理化性状、剖面构型、土壤养分、田间管理5个层面搜集获取16个评价指标数据,通过空间插值和以点代面的方法予全区耕地单元赋值,运用综合指数法、特尔斐法、层次分析模型法进行耕地等级评价。结果表明,全区耕地可以划分为四、五、六、七、八等地5个等级。全区参与评价的总耕地面积共25881.78hm^(2),其中四等地面积134.09hm^(2),占总耕地面积的0.52%;五等地面积1100.13hm^(2),占4.25%;六等地面积6935.80hm^(2),占26.80%;七等地面积9901.18hm^(2),占38.26%;八等地面积7810.58hm^(2),占30.18%。境内耕地一、二、三等高等级地未分布。由此可见,西峰区耕地质量总体偏低,耕地质量保护和提升工作任重道远。

关键词：西峰区耕地质量等级评价质量提升

不同剂量罗库溴铵对腔镜甲状腺切除术中喉返神经监测的影响

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临床麻醉学杂志 2024年第6期40卷 597-600页

作者：杨亚宁田仙龄马富强马倩马洪军陈学新宁夏医科大学临床医学院银川市750004 宁夏医科大学总医院肿瘤医院麻醉科

目的探讨不同剂量罗库溴铵对腔镜甲状腺切除术中喉返神经监测的影响。方法选择2021年10月至2022年10月行经乳晕入路腔镜甲状腺切除术的患者116例,男30例,女86例,年龄18~64岁,BMI 18.5~30.0 kg/m^(2),ASAⅠ或Ⅱ级。采用随机数字表法将患... 详细信息

目的探讨不同剂量罗库溴铵对腔镜甲状腺切除术中喉返神经监测的影响。方法选择2021年10月至2022年10月行经乳晕入路腔镜甲状腺切除术的患者116例,男30例,女86例,年龄18~64岁,BMI 18.5~30.0 kg/m^(2),ASAⅠ或Ⅱ级。采用随机数字表法将患者分为三组:罗库溴铵0.30 mg/kg组(R1组,n=39)、罗库溴铵0.45 mg/kg(R2组,n=39)和罗库溴铵0.60 mg/kg(R3组,n=38)。麻醉诱导后,R1组、R2组和R3组分别静脉注射罗库溴铵0.30、0.45、0.60 mg/kg。当TOF值为0后插入神经监测气管导管,术中全程监测肌松,神经监测结束前不追加肌松药。记录首次出现喉返神经肌电图(EMG)时间及EMG振幅、插管时间及气管插管质量(Cooper’s评分法)。记录术中低血压、高血压、心动过缓、心动过速、体动的发生情况。记录术后咽痛、声音嘶哑、肌肉疼痛的发生情况。结果三组首次出现喉返神经EMG时间差异无统计学意义。与R1组比较,R2组和R3组首次出现喉返神经EMG振幅明显降低(P<0.05)。与R1组比较,R2组和R3组插管时间明显缩短(P<0.05)。与R2组比较,R3组插管时间明显缩短(P<0.05)。与R1组比较,R2组和R3组气管插管质量明显升高(P<0.05)。与R1组比较,R2组和R3组术中体动、术后咽痛发生率明显降低(P<0.05)。结论在腔镜甲状腺切除术中,与罗库溴铵0.30 mg/kg比较,罗库溴铵0.45和0.60 mg/kg既能提供良好的气管插管条件,又能监测到喉返神经肌电信号,罗库溴铵0.60 mg/kg插管时间更短。

关键词：罗库溴铵喉返神经腔镜甲状腺手术神经肌肉监测