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The Study on University Literature Teaching based on Multimedia Technology

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International English Education Research 2014年第9期 10-12页

作者： yanhui zhang Wuhan Polytechnic Wuhan China 430074

currently, the multimedia language teaching has gradually entered the university, the old and the young program, and gradually plays a great charm, and gradually influence and change the traditional language teaching. Multimedia is a new technology lived in a simple or synthesized form shown by the text, the graphics, the images, the animation as well as audio, video and other information, which processed through the computer＇s software and hardware. I apply this new technology in teaching that＇ s the multimedia teaching.

关键词： university literature teaching multimedia technology traditional teaching

Branch-Activated Multi-Domain Convolutional Neural Network for Visual Tracking

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Journal of Shanghai Jiaotong university(Science) 2018年第3期23卷 360-367页

作者： CHEN Yimin LU Rongron ZOU Yibo zhang yanhui School of Computer Engineering and Science Shanghai University Shanghai 200444 China

Convolutional neural networks （CNNs） have been applied in state-of-the-art visual tracking tasks to represent the target. However, most existing algorithms treat visual tracking as an object-specific task. Therefore, the model needs to be retrained for different test video sequences. We propose a branch-activated multi-domain convolutional neural network （BAMDCNN）. In contrast to most existing trackers based on CNNs which require frequent online training, BAMDCNN only needs offine training and online fine-tuning. Specifically, BAMDCNN exploits category-specific features that are more robust against variations. To allow for learning category-specific information, we introduce a group algorithm and a branch activation method. Experimental results on challenging benchmark show that the proposed algorithm outperforms other state-of-the-art methods. What＇s more, compared with CNN based trackers, BAMDCNN increases tracking speed.

关键词： convolutional neural network(CNN) category-specific feature group algorithm branch activation method

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SiP模组自动点胶贴片技术

电子工艺技术 2024年第5期45卷 39-42,51页

作者：李颖凡周太富张艳辉欧姗姗胡志权中国电子科技集团公司第十研究所成都610036 中国电子科技集团公司第二研究所太原030024

SiP模组的自动点胶贴片相比手动方式,存在胶量少、对位精度难以控制、芯片剪切强度低以及电性能指标下降等工艺难题。在进行大量的自动点胶贴片工艺试验分析基础上,通过正交试验方法实现工艺参数优化,归纳总结出一套有效的自动点胶贴片... 详细信息

SiP模组的自动点胶贴片相比手动方式,存在胶量少、对位精度难以控制、芯片剪切强度低以及电性能指标下降等工艺难题。在进行大量的自动点胶贴片工艺试验分析基础上,通过正交试验方法实现工艺参数优化,归纳总结出一套有效的自动点胶贴片工艺方案,成功应用于各类型平台上的毫米波相控阵SiP模组生产中,显著提升了产品的芯片贴装质量。

关键词： SiP模组自动点胶贴片工艺参数优化

ENO1 expression and Erk phosphorylation in PDAC and their effects on tumor cell apoptosis in a hypoxic microenvironment

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Cancer Biology & Medicine 2022年第11期19卷 1598-1616页

作者： Huizhi Sun Jing Mo Runfen Cheng Fan Li Yue Li Yuhong Guo Yanlei Li yanhui zhang Xiaoyu Bai Yalei Wang Xueyi Dong Danfang zhang Jihui Hao Tianjin Medical University Cancer Institute&Hospital National Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjinTianjin's Clinical Research Center for CancerTianjin 300060China Department of Pathology Tianjin Medical UniversityTianjin300070China

Objective: Hypoxia is an important feature of pancreatic ductal adenocarcinoma(PDAC). Previously, we found that hypoxia promotes ENO1 expression and PDAC invasion. However, the underlying molecular mechanism was remains ***: The relationship between ENO1 expression and clinicopathological characteristics was analyzed in 84 patients with PADC. The effects of CoCl2-induced hypoxia and ENO1 downregulation on the apoptosis, invasion, and proliferation of PDAC cells were evaluated in vitro and in vivo. Hypoxia-and ENO1-induced gene expression was analyzed by transcriptomic ***: The prognosis of PDAC with high ENO1 expression was poor(P < 0.05). High ENO1 expression was closely associated with histological differentiation and tumor invasion in 84 PDAC cases(P < 0.05). Hypoxia increased ENO1 expression in PDAC and promoted its migration and invasion. Apoptotic cells and the apoptosis marker caspase-3 in the CoCl_(2)-treated ENO1-sh group were significantly elevated(P < 0.05). Transcriptomic sequencing indicated that CoCl_(2)-induced PDAC cells initiated MAPK signaling. Under hypoxic conditions, PDAC cells upregulated ENO1 expression, thereby accelerating ERK phosphorylation and inhibiting apoptosis(P < 0.05). Consistent results were also observed in a PDAC-bearing mouse hindlimb ischemia ***: Hypoxia-induced ENO1 expression promotes ERK phosphorylation and inhibits apoptosis, thus leading to PDAC survival and invasion. These results suggest that ENO1 is a potential therapeutic target for PDAC.

关键词： Pancreatic cancer hypoxia ENOl apoptosis Erk phosphorylation

The relationship between single nucleotide polymorphisms in estrogenmetabolizing genes CYP1A1,CYP17,COMT and estrogen receptor alpha and the risk of endometrial adenocarcinoma among the Chinese women

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现代妇产科进展 2007年第1期16卷 76-80页

作者： Yang Xingsheng Liu Jie Zhong yanhui zhang Xian Wang Yan Department of Gynecology and Obstetrics Qilu Hospital of Shandong University Jinan 250012

Objective:To explore whether polymorphisms of the genes responsible for catechol estrogen(CE)formation via estrogen biosynthesis(CYP17)and hydroxylation (CYP1A1)and CE inactivation(COMT)and ERa are associated with an elevated risk for en- dometrial adenocarcinoma in Chinese ***:A multigenic case-control study was conducted,eighty-seven endometrial adenocarcinoma patients and ninety controls were recrui- ***-RFLP assays were used to determine the genotypes of estrogen-metabolizing genes and ERa ***:The endometrial adenocarcinoma risk associated with individual susceptibili- ty genotypes varied among the six polymorphic sites and was the highest for CYP17,followed by CYP1 A1 Ile-Val,CYP1A1 MspI,COMT,ERa XhaI and ERa *** logistic regres- sion showed the CYP1A1 MspI genotype was the most significant determinant for endometrial adenocarcinoma development and was associated with a 3.61 fold increase in risk(95% confi- dence interval,1.73～7.55).Furthermore,a trend of increasing risk for developing endometrial adenocarcinoma was found in women harboring higher numbers of high-risk ***- sion:The CYP1A1,CYP17 and ERa XbaI genotypes are related to the susceptibility of endome- trial adenocarcinoma,they may be useful markers for predicting endometrial adenocarcinoma *** allele encoding for low acticity COMT,ERa PvuII may not be a genetic risk factor for endometrial adenocarcinoma.

关键词：子宫内膜肿瘤基因治疗方法护理措施

Quantification of the concrete freeze–thaw environment across the Qinghai–Tibet Plateau based on machine learning algorithms

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Journal of Mountain Science 2024年第1期21卷 322-334页

作者： QIN yanhui MA Haoyuan zhang Lele YIN Jinshuai ZHENG Xionghui LI Shuo Department of Civil Engineering Qingdao University of TechnologyQingdao 266520China Department of Geography Qinghai Normal UniversityXining 810008China

The reasonable quantification of the concrete freezing environment on the Qinghai–Tibet Plateau(QTP) is the primary issue in frost resistant concrete design, which is one of the challenges that the QTP engineering managers should take into account. In this paper, we propose a more realistic method to calculate the number of concrete freeze–thaw cycles(NFTCs) on the QTP. The calculated results show that the NFTCs increase as the altitude of the meteorological station increases with the average NFTCs being 208.7. Four machine learning methods, i.e., the random forest(RF) model, generalized boosting method(GBM), generalized linear model(GLM), and generalized additive model(GAM), are used to fit the NFTCs. The root mean square error(RMSE) values of the RF, GBM, GLM, and GAM are 32.3, 4.3, 247.9, and 161.3, respectively. The R^(2) values of the RF, GBM, GLM, and GAM are 0.93, 0.99, 0.48, and 0.66, respectively. The GBM method performs the best compared to the other three methods, which was shown by the results of RMSE and R^(2) values. The quantitative results from the GBM method indicate that the lowest, medium, and highest NFTC values are distributed in the northern, central, and southern parts of the QTP, respectively. The annual NFTCs in the QTP region are mainly concentrated at 160 and above, and the average NFTCs is 200 across the QTP. Our results can provide scientific guidance and a theoretical basis for the freezing resistance design of concrete in various projects on the QTP.

关键词： Freeze–thaw cycles Quantification Machine learning algorithms Qinghai–Tibet Plateau Concrete

Multiplexed manipulation of orbital angular momentum and wavelength in metasurfaces based on arbitrary complex-amplitude control

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Light(Science & Applications) 2024年第5期13卷 930-940页

作者： Guoli He Yaqin Zheng Changda Zhou Siyang Li Zhonghong Shi yanhui Deng zhang-Kai Zhou State Key Laboratory of Optoelectronic Materials and Technologies School of PhysicsSun Yat-sen UniversityGuangzhou 510275China

Due to its unbounded and orthogonal modes,the orbital angular momentum(OAM)is regarded as a key optical degree of freedom(DoF)for future information processing with ultra-high capacity and *** the manipulation of OAM based on metasurfaces has brought about great achievements in various fields,such manipulation currently remains at single-DoF level,which means the multiplexed manipulation of OAM with other optical DoFs is still lacking,greatly hampering the application of OAM beams and advancement of *** order to overcome this challenge,we propose the idea of multiplexed coherent pixel(MCP)for *** approach enables the manipulation of arbitrary complex-amplitude under incident lights of both plane and OAM waves,on the basis of which we have realized the multiplexed DoF control of OAM and *** a result,the MCP method expands the types of incident lights which can be simultaneously responded by metasurfaces,enriches the information processing capability of metasurfaces,and creates applications of information encryption and OAM *** findings not only provide means for the design of high-security and high-capacity metasurfaces,but also raise the control and application level of OAM,offering great potential for multifunctional nanophotonic devices in the future.

关键词： momentum offering overcome

Application of fluid modulus inversion to complex lithology reservoirs in deep-water areas

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Energy Geoscience

Energy Geoscience 2024年第1期5卷 153-161页

作者： Zhaoming Chen Huaxing Lyu Zhongtao zhang yanhui Zhu Baojun Liu CNOOC Deepwater Development Limited ShenzhenGuangdong518054China

It has been a challenge to distinguish between seismic anomalies caused by complex lithology and hydrocarbon reservoirs using conventional fluid identification techniques,leading to difficulties in accurately predicting hydrocarbon-bearing properties and determining oil-water contacts in *** this study,we built a petrophysical model tailored to the deep-water area of the Baiyun Sag in the eastern South China Sea based on seismic data and explored the feasibility of the tri-parameter direct inversion method in the fluid identification of complex lithology reservoirs,offering a more precise alternative to conventional *** research found that the fluid modulus can successfully eliminate seismic amplitude anomalies caused by lithological ***,the seismic databased direct inversion for fluid modulus can remove the cumulative errors caused by indirect inversion and the influence of *** discovered that traditional methods using seismic amplitude anomalies were ineffective in detecting fluids,determining gas-water contacts,or delineating high-quality ***,the fluid factor Kf,derived from solid-liquid decoupling,proved to be sensitive to the identification of hydrocarbon-bearing properties,distinguishing between high-quality and poor-quality gas *** findings confirm the value of the fluid modulus in fluid identification and demonstrate that the tri-parameter direct inversion method can significantly enhance hydrocarbon exploration in deep-water areas,reducing associated risks.

关键词： Fluid identification Seismic fluid factor Solid-liquid decoupling Deep-water area Complex lithology reservoir

A general strategy for selective detection of hypochlorous acid based on triazolopyridine formation

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Chinese Chemical Letters 2020年第11期31卷 2917-2920页

作者： yanhui zhang Hao Teng Ying Gao Muhammad Wasim Afzal Jingye Tian Xi Chen Haoyang Tang Tony D.James Yuan Guo Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education National Demonstration Center for Experimental Chemistry EducationCollege of Chemistry and Materials ScienceNorthwest UniversityXi'an 710127China School of Automation Xi'an University of Posts and TelecommunicationsXi'an 710121China Department of Chemistry University of BathBathBA27AYUnited Kingdom

Triazolopyridines are an important kind of fused-ring compounds.A HOCl-promoted triazolopyridine formation strategy is reported here for the first time in which hypochlorous acid(HOCl)mildly and efficiently promotes the formation of 1,2,4-triazolo[4,3-a]pyridines NT1-NT6 from various 2-pyridylhydrazones N1-N6.N6,a rhodol-pyridylhydrazone hybrid,was developed into a fluorescent probe for the selective detection of HOCl,and successfully applied to probe endogenous HOCl in living cells and zebrafish in situ and in real *** present intramolecular cyclization reaction is selective and atom-economical,thereby not only providing an important approach for the convenient synthesis of triazolopyridines,but also offering a general strategy for sensitive,selective and biocompatible detection of endogenous HOCl in complex biosystems.

关键词： Triazolopyridines 2-Pyridylhydrazones Fluorescent probes Reactive oxygen species Hypochlorous acid