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Large-scale land-sea interactions extend ozone pollution duration in coastal cities along northern China

Environmental Science and Ecotechnology 2024年第2期18卷 150-160页

作者： yanhua zheng Fei Jiang Shuzhuang Feng Yang Shen Huan Liu Hai Guo Xiaopu Lyu Mengwei Jia Chenxi Lou Jiangsu Provincial Key Laboratory of Geographic Information Science and Technology International Institute for Earth System ScienceNanjing UniversityNanjing210023China Jiangsu Center for Collaborative Innovation in Geographical Information Resource Development and Application Nanjing210023China Frontiers Science Center for Critical Earth Material Cycling Nanjing UniversityNanjing210023China School of Environment Tsinghua UniversityBeijing100084China Air Quality Studies Department of Civil and Environmental EngineeringHong Kong Polytechnic UniversityHong KongChina

Land-sea atmosphere interaction(LSAI)is one of the important processes affecting ozone(O_(3))pollution in coastal *** effects of small-scale LSAIs like sea-land breezes have been widely ***,it is not fully clear how and to what extent the large-scale LSAIs affect O_(3) *** we explored an O_(3) episode to illuminate the role of large-scale LSAIs in O_(3) pollution over the BohaieYellow Seas and adjacent areas through observations and model *** results show that the northern Bohai Sea's coastal region,influenced by the Mongolian High,initially experienced a typical unimodal diurnal O_(3) variation for three days,when O_(3) precursors from BeijingeTianjineHebei,Shandong,and Northeast China were transported to the BohaieYellow *** reactions generated O_(3) within marine air masses,causing higher O_(3) levels over the seas than coastal *** the Mongolian High shifted eastward and expanded,southerly winds on its western edge transported O_(3)-rich marine air masses toward the coast,prolonging pollution for an additional three days and weakening diurnal ***,emissions from the Korean Peninsula and marine shipping significantly affected O_(3) levels in the northern Bohai Sea(10.7%and 13.7%,respectively).Notably,Shandong's emissions played a substantial role in both phases(27.5%and 26.1%,respectively).These findings underscore the substantial impact of large-scale LSAIs driven by the Mongolian High on O_(3) formation and pollution duration in coastal *** insight helps understand and manage O_(3) pollution in northern Bohai Sea cities and broadly applies to temperate coastal cities worldwide.

关键词： Mongolian high Source apportionment WRF-CMAQ Sea-crossing transport

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Regulation of tumor cell migration by protein tyrosine phosphatase (PTP)-proline-, glutamate-, serine-,and threonine-rich sequence(PEST)

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Chinese Journal of Cancer 2013年第2期32卷 75-83页

作者： yanhua zheng Zhimin Lu Brain Tumor Center and Department of Neuro-Oncology The University of Texas MD Anderson Cancer Center Department of Molecular and Cellular Oncology The University of Texas MD Anderson Cancer Center The University of Texas Graduate School of Biomedical Sciences at Houston

Protein tyrosine phosphatase (PTP)-proline-,glutamate-,serine-,and threonine-rich sequence (PEST) is ubiquitously expressed and is a critical regulator of cell adhesion and ***-PEST activity can be regulated transcriptionally via gene deletion or mutation in several types of human cancers or via post-translational modifications,including phosphorylation,oxidation,and caspase-dependent ***-PEST interacts with and dephosphorylates cytoskeletal and focal adhesion-associated ***-phorylation of PTP-PEST substrates regulates their enzymatic activities and/or their interaction with other proteins and plays an essential role in the tumor cell migration process.

关键词：蛋白酪氨酸磷酸酶细胞迁移 PEST 肿瘤细胞脯氨酸 PTP 谷氨酸丝氨酸

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非酒精性脂肪肝病和心力衰竭:临床证据和病理生理学机制

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安徽医药 2024年第3期28卷 451-456页

作者：郑焱华卢俊会陈星山西医科大学第二医院消化内科山西太原030001 山西医科大学第一医院消化内科山西太原030012 山西医科大学第一医院胃肠外科山西太原030012

非酒精性脂肪性肝病(NAFLD)和心力衰竭(心衰)是两大重要的公共健康问题。NAFLD增加心血管疾病(冠状动脉疾病、心房颤动、高血压、心肌病、心衰)风险间接或直接与心衰关联。NAFLD通过胰岛素抵抗、肾素-血管紧张素-醛固酮系统和交感神经... 详细信息

非酒精性脂肪性肝病(NAFLD)和心力衰竭(心衰)是两大重要的公共健康问题。NAFLD增加心血管疾病(冠状动脉疾病、心房颤动、高血压、心肌病、心衰)风险间接或直接与心衰关联。NAFLD通过胰岛素抵抗、肾素-血管紧张素-醛固酮系统和交感神经系统的激活、全身炎症、氧化应激、肠道菌群失调和扩张的异位脂肪等病理生理学机制促进心脏重塑和心衰的发生和进展。该研究总结了NAFLD与心衰关联的临床证据和病理生理学机制,及这两种疾病可能的管理和治疗。

关键词：非酒精性脂肪性肝病心力衰竭心血管疾病病理生理学治疗

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炔雌醇环丙孕酮片配合宫腔镜术用于围绝经期异常子宫出血患者的价值

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中外医学研究 2024年第1期22卷 121-124页

作者：胡利红郑艳华将乐县总医院福建将乐353300

目的:研究炔雌醇环丙孕酮片配合宫腔镜术(HS)用于围绝经期异常子宫出血(AUB)患者的价值。方法:选取2019年6月—2021年6月在将乐县总医院进行治疗的152例围绝经期AUB患者作为研究对象,采用随机数表法分为观察组和对照组,各76例。对照组使... 详细信息

目的:研究炔雌醇环丙孕酮片配合宫腔镜术(HS)用于围绝经期异常子宫出血(AUB)患者的价值。方法:选取2019年6月—2021年6月在将乐县总医院进行治疗的152例围绝经期AUB患者作为研究对象,采用随机数表法分为观察组和对照组,各76例。对照组使用HS治疗,观察组使用炔雌醇环丙孕酮片配合HS治疗。比较两组治疗前后的激素水平[催乳素(PRL)、雌二醇(E_(2))、黄体生成素(LH)、卵泡刺激素(FSH)]、出血停止时间、月经量[月经失血图(PBAC)]、不良反应发生率、血红蛋白浓度及子宫内膜厚度。结果:治疗后,两组PRL、E_(2)、LH、FSH水平均低于治疗前,且观察组低于对照组,差异有统计学意义(P0.05)。治疗后,两组血红蛋白浓度高于治疗前,子宫内膜厚度低于治疗前,且观察组血红蛋白浓度高于对照组,子宫内膜厚度低于对照组,差异有统计学意义(P<0.05)。结论:采用炔雌醇环丙孕酮片配合HS治疗围绝经期AUB患者能降低其激素水平,缩短止血时间,减少月经量,提高血红蛋白浓度,降低子宫内膜厚度,且较为安全。

关键词：炔雌醇环丙孕酮片围绝经期异常子宫出血激素宫腔镜术

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Brassinosteroids inhibit miRNA-mediated translational repression by decreasing AGO1 on the endoplasmic reticulum

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Journal of Integrative Plant Biology 2021年第8期63卷 1475-1490页

作者： Taiyun Wang yanhua zheng Qi Tang Songxiao Zhong Wei Su Binglian zheng State Key Laboratory of Genetic Engineering Ministry of Education Key Laboratory of Biodiversity Sciences and Ecological EngineeringCollaborative Innovation Center of Genetics and DevelopmentInstitute of Plant BiologySchool of Life SciencesFudan UniversityShanghai200438 China

Translational repression is a conserved mechanism in microRNA(miRNA)-guided gene *** Arabidopsis,ARGONAUTE1(AGO1),the major miRNA effector,localizes in the cytoplasm for mRNA cleavage and at the endoplasmic reticulum(ER)for translational repression of target ***,the mechanism underlying miRNA-mediated translational repression is poorly *** particular,how the subcellular partitioning of AGO1 is regulated is largely ***,we show that the plant hormone brassinosteroids(BRs)inhibit miRNA-mediated translational repression by negatively regulating the distribution of AGO1 at the ER in Arabidopsis *** show that the protein levels rather than the transcript levels of miRNA target genes were reduced in BR-deficient mutants but increased under BR *** localization of AGO1 at the ER was significantly decreased under BR treatments while it was increased in the BR-deficient ***,ROTUNDIFOLIA3(ROT3),an enzyme involved in BR biosynthesis,co-localizes with AGO1 at the ER and interacts with AGO1 in a GW motif-dependent *** analysis showed that the AGO1-ROT3 interaction is necessary for the function of *** findings provide new clues to understand how miRNA-mediated gene silencing is regulated by plant endogenous hormones.

关键词： AG01 Arabidopsis thaliana brassinosteroids endoplasmic reticulum miRNA translational repression

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Chinese version of NCCN Clinical Practice Guidelines in Oncology officially authorized by NCCN

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Chinese Journal of Cancer Research 2016年第1期28卷 144-145页

作者： yanhua zheng Dingyao Xu Zhaode Bu Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Editorial Department of Chinese Journal of Cancer Research Peking University Cancer Hospital & Institute Beijing 100142 China

The publishing conference of the Chinese version of National Comprehensive Cancer Network （NCCN） Clinical Practice Guidelines in Oncology （hereinafter referred to as NCCN Guidelines） and the inaugural peer reviewer meeting of NCCN Clinical Practice Guidelines in Oncology： Digestive System Cancers （hereinafter referred to as NCCN Guidelines on Digestive System Cancers） were held in People＇s Medical Publishing House in January 28^th, 2016 （Figure 1）.

关键词： Chinese version of NCCN Clinical Practice Guidelines in Oncology officially authorized by NCCN

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循经取穴贴敷疗法对腰椎内固定术后患者胃肠功能的影响

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实用医学杂志 2024年第2期40卷 267-271页

作者：赖培茜胡佩王洪伸郑延华蓝梅妍陈少华广州中医药大学第二附属医院广州510120

目的观察循经取穴贴敷疗法对腰椎内固定术后患者胃肠功能恢复的疗效。方法选取2020年1月至2022年3月在广州中医药大学第二附属医院收治的125例腰椎内固定术后患者,按随机数字表法分为对照组和观察组:对照组62例为常规腰椎内固定术后护理... 详细信息

目的观察循经取穴贴敷疗法对腰椎内固定术后患者胃肠功能恢复的疗效。方法选取2020年1月至2022年3月在广州中医药大学第二附属医院收治的125例腰椎内固定术后患者,按随机数字表法分为对照组和观察组:对照组62例为常规腰椎内固定术后护理,观察组63例在常规护理的基础上加用循经取穴贴敷疗法,观察两组患者术后恶心呕吐NVAS评分、腹胀腹痛、肠鸣音与首次排气、排便时间。结果两组患者术后均发生不同程度的胃肠功能障碍。其中观察组恶心人数、恶心NVAS评分、呕吐分级、腹胀发生率、肠鸣音恢复正常时间和首次排气、排便时间,均较对照组降低(均P0.05)。2组均未发生不良反应。结论循经取穴贴敷疗法可加快腰椎内固定术后患者胃肠功能恢复,促进术后快速康复,提高生活质量。

关键词：腰椎内固定术循经取穴贴敷疗法胃肠功能快速康复

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血府逐瘀汤对急性加重期COPD患者肺功能指标、炎症指标的影响观察

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四川中医 2024年第4期42卷 131-135页

作者：郑艳华谢亮亮宋春芳涡阳县中医院肺病科安徽涡阳233600 涡阳县中医院中医科安徽涡阳233600 涡阳县中医院感染科安徽涡阳233600

目的:评价血府逐瘀汤联合常规西医治疗对急性加重期慢性阻塞性肺病(COPD)患者的肺功能指标和炎症指标的影响。方法:本研究于2020年10月~2023年6月,研究对象为本院呼吸科82例急性加重期COPD患者,采用随机数字表法分成两组。对照组(41例)... 详细信息

目的:评价血府逐瘀汤联合常规西医治疗对急性加重期慢性阻塞性肺病(COPD)患者的肺功能指标和炎症指标的影响。方法:本研究于2020年10月~2023年6月,研究对象为本院呼吸科82例急性加重期COPD患者,采用随机数字表法分成两组。对照组(41例)仅接受常规西医治疗,观察组(41例)接受常规西医联合使用血府逐瘀汤治疗。比较两组临床疗效、中医证候积分、肺功能指标[用力肺活量(FVC)、一秒用力呼气容积(FEV1)、肺一氧化碳弥散量(DLCO)]、炎症指标[白细胞计数(WBC)、血清白介素6(IL-6)、白三烯B4(LT-B4)、超敏C反应蛋白(hs-CRP)]。结果:观察组治疗总有效率为90.24%(37/41)显著高于对照组73.17%(30/41),差异显著(P0.05),治疗后,观察组中医证候积分显著低于对照组(P0.05);观察组的炎症因子水平显著低于对照组(P<0.05)。结论:血府逐瘀汤结合常规西医治疗能够有效提升急性加重期COPD患者的肺功能,并减少炎症因子的水平,为COPD患者的综合治疗提供了一种新的有效方案。

关键词：血府逐瘀汤慢性阻塞性肺病肺功能炎症因子

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Different Activities of Osteoblast and Bacteria on a Nanostructured Titanium Surface for Dental Implant 2nd

Different Activities of Osteoblast and Bacteria on a Nanostr...

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2nd International Conference on Advanced Materials and Information Technology Processing(AMITP 2012)

作者： zheng yanhua Li Jinbo Liu Xuanyong Sun Jiao Shanghai Ninth People’s Hospital Shanghai Jiaotong University School of Medicine Shanghai Institute of Ceramics Chinese Academy of Science

ISBN: (纸本)9783037855232

Insufficience of osteogenesis and antimicrobial effect have been still impacted the long term clinical success rate of dental implants. A nanostructured titanium surface prepared by hydrothermal treatment with HO was evaluated on its osteoblastic viability and antibacterial effect. Samples were divided into 2 groups: untreated pure titanium surface(Ti) and a nanostructured titanium surface(NT). The antibacterial activities against *** and *** were measured by film applicator coating assay, as well as the live/dead bacteria stain. The osteoblastic viability was investigated by SEM and MTT assay. Results showed that the active microbia on NT was reduced at 24h(P<0.05) significantly according to the live/dead bacteria stain and film applicator coating assay, which could also enhance the osteoblast viability. Therefore, a nanostructured titanium surface exhibits good antibacterial activity on *** and ***, and promoting osteoblast viability, which will be a potential kind of dental implant material.

关键词： Titanium Nanostructure Streptococcus mutans Candiada albicans Osteoblast

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Antibacterial properties of cerium oxide nanoparticles:Recent progresses and future challenges

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Particuology 2024年第10期93卷 264-283页

作者： Heishu zheng Jiajing Tang yanhua Wei Xi Deng Yingjuan Zhang Xiangyu Ma Xudong Jiang Zhi Ping Xu Hongbing Liao College&Hospital of Stomatology Guangxi Medical UniversityNanning530021China Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction Guangxi Medical UniversityNanning530021China The First Affiliated Hospital of Guangxi Medical University Nanning530021China School of Medicine Guangxi University of Science and TechnologyLiuzhou545005China Institute of Biomedical Health Technology and Engineering and Institute of Systems and Physical Biology Shenzhen Bay LaboratoryShenzhen518107China Australian Institute for Bioengineering and Nanotechnology(Bld 75) The University of QueenslandSt LuciaQueensland 4074Australia

Use of cerium oxide nanoparticles(CeO_(2) NPs)to optimize management of resistant microorganisms has received increasing attention due to non-specific activity of inorganic antibacterial *** the mechanism of action is essential to elucidating the antibacterial activity of CeO_(2) NPs against ***,this review aims to summarize the antibacterial mechanisms of CeO_(2) NPs and correlate the structural and physicochemical properties of CeO_(2) NPs to their antibacterial *** further summarize the strategies for the improvement of the antibacterial performance of CeO_(2) NPs and provide our opinions for future challenges as a conclusion.

关键词： Nanoparticles Cerium oxide Antibacterial activity Nanozyme Fenton reaction

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