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A Novel Electrochemical Reactor for Nitrogen and Phosphorus Recovery from Domestic Wastewater

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Frontiers of Environmental Science & Engineering 2017年第4期11卷 139-144页

作者： Shiting Ren Mengchen Li Jianyu Sun yanhong bian Kuichang Zuo Xiaoyuan Zhang Peng Liang Xia Huang State Key Joint Laboratory of Environment Simulation and Pollution Control School of Environment Tsinghua University Beijing 100084 China

To separate and concentrate NH4＋ and PO43 from the synthetic wastewater to the concentrated solution through a novel electrochemical reactor with circulated anode and cathode using the difference of the concentration between electrode chamber and middle *** recent years, the research on electrochemical processes have been focused on phosphate and ammonium removal and recovery. Among the wide range of possibilities with regards to electrochemical processes, capacitive deionization （CDI） saves the most energy while at the same time does not have continuity and selectivity. In this study, a new electrochemical reactor with electrolyte cyclic flowing in the electrode chambers was constructed to separate and concentrate phosphate and ammonium continuously and selectively from wastewater, based on the principle of CDI. At the concentration ratio of NaCI solution between the electrode chambers and the middle chamber （r） of 25 to 1, phosphate and ammonium in concentration level of domestic wastewater can be removed and recovered continuously and selectively as struvite. Long-term operation also indicated the ability to continuously repeat the reaction and verified sustained stability. Further, the selective recovery at the certain r could also be available to similar technologies for recovering other kinds of substances.

关键词： Nutrients recovery Electrochemical reactor Electrolyte cyclic flowing Concentration ratio Struvite

The convergence of lactic acid microbiomes and metabolites in long-term electrofermentation

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Environmental Science and Ecotechnology 2024年第6期22卷 256-265页

作者： Aaron Leininger Sidan Lu Jinyue Jiang yanhong bian Harold D.May Zhiyong Jason Ren Department of Civil and Environmental Engineering Princeton UniversityUSA Andlinger Center for Energy and the Environment Princeton UniversityUSA

Regulating electron transfer in predominantly fermentative microbiomes has broad implications in environmental,chemical,food,and medical *** we demonstrate electrochemical control in fermenting food waste,digestate,and wastewater to improve lactic acid *** hypothesize that applying anodic potential will expedite and direct fermentation towards lactic *** operation that introduced epi/endophytic communities(Lactococcus,Lactobacillus,Weissella)to pure culture Lactiplantibacillus plantarum reactors with static electrodes was associated with the loss of anode-induced process intensification despite 80%*** *** fluidized electrodes discouraged biofilm formation and extended electrode influence to planktonic gram-positive fermenters using mediated extracellular electron *** short-term experiments differentially enriched Lactococcus and Klebsiella spp.,longer-term operations indicated convergent microbiomes and product *** results highlight a functional resilience of environmental fermentative microbiomes to perturbations in redox potential,underscoring the need to better understand electrode induced polymicrobial interactions and physiological impacts to engineer tunable open-culture or synthetic consortia.

关键词： Fermentation Food wasteLactic acid Microbiome Electrofermentation Resource recovery

ADVANCE SELLING IN THE PRESENCE OF PRODUCT DIFFUSION EFFECT

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Journal of Systems Science and Systems Engineering 2017年第1期26卷 77-99页

作者： Xiaoyan Xu Xuemei Li Yiwen bian yanhong Sun School of Management University of Science & Technology of China Hefei 230026 China School of Management Zhejiang University Hangzhou 310058 China SHU-UTS SILC Business School Shanghai University Shanghai 201899 China

Product diffusion refers to the phenomenon that the later demand is dependent on the early sales. To investigate how a firm＇s advance selling strategy is affected by the effect of product diffusion, we consider a monopolist seller who sells a fashionable product in a market that comprises of myopic and strategic consumers over two periods （i.e., the advance selling season and the regular selling season）. For a linear product diffusion effect we fred that, when the effect of product diffusion is positive, the seller may set an extremely high advance selling price to induce the strategic consumers to purchase in the regular selling season, which is counter-intuitive. Moreover, the optimal procurement quantity for the seller may increase in the negative effect of product diffusion and decrease in the amount of strategic consumers. When we extend our model to consider a concave quadratic product diffusion effect, however, the optimal procurement quantity is concave in the amount of strategic consumers. Numerical studies are further presented to discuss the managerial insights.

关键词： Advance selling product diffusion strategic consumer behavior interface on marketing andoperations management

A Bionic Optimization Technique with Cockroach Biological Behavior

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Chinese Journal of Electronics 2021年第4期30卷 644-651页

作者： CHENG Le CHANG Lyu SONG yanhong WANG Haibo XU Yihan bian Yuetang College of Computer Science and Communication Jiangsu Vocational College of Electronics and Information College of Computer and Information Hohai University School of Business Nanjing Normal University

Many practical engineering problems can be abstracted as corresponding function optimization problems. During the last few decades, many bionic algorithms have been proposed for this problem. However,when optimizing for large scale problems, such as 1000 dimensions, many existing search techniques may no longer perform well. Inspired by the social model of cockroaches,this paper presents a novel search technique called Cooperation cockroach colony optimization(CCCO). In the CCCO algorithm, two kinds of special biological behavior of cockroach, wall-following and nest-leaving,are simulated and the whole population is divided into wall-following and nest-leaving populations. By the collaboration of the two populations, CCCO accomplishes the computation of global optimization. The crucial parameters of CCCO are set by the self-adaptive ***, a discussion on group model design is provided in this paper. The CCCO algorithm is evaluated with shifted test functions(1000 dimensions). Three state-ofthe-art cockroach-inspired algorithms are used for the comparative experiments. Furthermore, CCCO is applied to a real-world optimization problem concerning spread spectrum radar poly-phase. Experiment results show that the CCCO algorithm can be applied to optimize large-scale problems with the good performance.

关键词： Function optimization Cooperation cockroach colony optimization Wall-following Nestleaving

影响神经危重症患者预后不良的危险因素分析及预测模型构建

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交通医学 2023年第3期37卷 242-247,251页

作者：顾沈燕王玉琴柯开富成亚琴卞艳红钱海兰张元媛南通大学医学院江苏226001 通州区人民医院神经内科南通大学附属医院神经内科

目的:探讨影响神经危重症患者短期预后不良的危险因素,构建预后列线图预测模型。方法:回顾性分析首次在南通大学附属医院神经内科重症监护病房(neurological intensive care unit,NICU)住院的神经内科危重症患者310例临床资料,根据出院... 详细信息

目的:探讨影响神经危重症患者短期预后不良的危险因素,构建预后列线图预测模型。方法:回顾性分析首次在南通大学附属医院神经内科重症监护病房(neurological intensive care unit,NICU)住院的神经内科危重症患者310例临床资料,根据出院时APACHEⅡ评分作为短期预后指标分为预后良好组161例和预后不良组149例。将患者入院时的指标作为自变量,采用Lasso回归及交叉验证的方法筛选变量,通过二元Logistic回归筛选影响患者短期预后的独立危险因素。搭建预测模型并绘制列线图,采用Bootstrap检验进行内部验证,以受试者工作特征曲线(receiver operator characteristic curve,ROC)、校准曲线、决策曲线分析(decision curve analysis,DCA)及临床影响曲线(clinical impact curve,CIC)验证模型的区分度、校准度及临床适用性。结果:机械通气、房颤、入院时血钙水平以及GCS评分是影响NICU患者短期预后的独立危险因素。入院时GCS评分、机械通气、入院时血钙水平、房颤的ROC曲线下面积(area under curve,AUC)分别为0.787、0.655、0.629及0.598,入院时GCS评分的AUC大于其他独立危险因素(P<0.001)。联合预测因子模型的AUC为0.861,校准后为0.854,显著大于其他独立危险因素(P<0.001)。ROC曲线及C统计量提示本模型区分度良好,校准曲线提示本模型校准度良好,而DCA曲线及CIC曲线则显示本模型具有良好的临床适用性。结论:机械通气、房颤、入院时血钙水平以及GCS评分是引起神经危重症患者预后不良的危险因素,构建的联合预测因子模型具有良好的预测能力,能定量而简明评价不同危险因素的风险,为神经危重症患者的精准医疗提供依据。

关键词：神经危重症预后危险因素列线图预测模型

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川东高陡构造带震旦系灯影组丘滩相气藏预测

天然气勘探与开发 2023年第3期46卷 1-13页

作者：周刚文龙王文之张本健严威魏朋辉蒋航和源汪华卞艳红曾云贤杨岱林中国石油西南油气田公司勘探开发研究院中国石油西南油气田公司北京源烃泰克科技有限公司

在川东高陡构造带内,构造复杂、地震资料差,寻找震旦系灯影组油气富集带具有重大挑战。为此,运用构造形迹分析构造期次,环状构造结合地震相特征预测藻丘滩;丘滩相特征结合构造形迹期次分析WT1井失利原因;综合丘滩相与构造的叠合关系以... 详细信息

在川东高陡构造带内,构造复杂、地震资料差,寻找震旦系灯影组油气富集带具有重大挑战。为此,运用构造形迹分析构造期次,环状构造结合地震相特征预测藻丘滩;丘滩相特征结合构造形迹期次分析WT1井失利原因;综合丘滩相与构造的叠合关系以预测开江地区灯影组油气富集带。结果表明:①开江地区的NE构造主体为川东高陡构造带在燕山中晚期挤压形成,喜山期强烈改造定型。②EW向低幅度构造为大巴山于晚燕山期弱挤压形成。③SN向构造形成于喜马拉雅晚期,动力来自龙门山南段挤压。④燕山中晚期的NE构造与裂解气富集晚期匹配。发育大量的环状构造,为藻丘滩刚性地质体形成,为古岩性圈闭,与原油成藏期匹配。⑤环状构造+NE向构造是油气富集带。综合构造形迹与地震相预测了多个油气目标:七里南背斜内的七3环是最有利目标,藻丘滩地震相最为明显,且叠加NE向构造;铁1环是现实的目标;里1环是潜在的目标区。环状构造在开江地区大量存在,具有较好的油气勘探远景。

关键词：川东高陡构造带开江古隆起灯影组藻丘滩构造形迹环状构造

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Experimental Study on Composition Optimization for Refining Slag Containing BaO

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China's Refractories 2007年第4期16卷 24-27页

作者： GAO yanhong bian Lingtao ZHANG Sanhua Chongqing University of Science and Technology Chongqing 400016 China Chongqing Hanlin Project Cost Consultant Co. Ltd.

Laboratory study; was carried out on deep desulfurization of molten steel by CaO-Al2O3 based refining slag containing BaO at 1873K to achieve lower sulphur level in steel. A mathematical model of desulfurization was established with the methodology of quadratic orthogohal regression. According to the modle, the influence of AlO3/CaO, MgO, CaF2, BaO in slag on desulfurization rate was analyzed. The results showed that the desulfurization rate almost linearly decreased with the increase of Al2O3/CaO and it increased firstly then decreased when MgO and BaO content increased respectixely, yet the trend is on the contrary as CaF2 content increased. Based on the comprehensive analysis, the optimum composition of the refining slag was achieved under the experimental conditions.

关键词： Refining slag Desulfurization Orthogo-nal re gression

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Cynomolgus-rhesus hybrid macaques serve as a platform for imprinting studies

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The Innovation 2023年第3期4卷 104-111页

作者： Zongyang Lu Jie Li Yong Lu Ling Li Wei Wang Chenchen Zhang Libing Xu yanhong Nie Changshan Gao Xinyan bian Zhen Liu Guang-Zhong Wang Qiang Sun Institute of Neuroscience CAS Center for Excellence in Brain Science and Intelligence TechnologyCAS Key Laboratory of Primate NeurobiologyState Key Laboratory of NeuroscienceChinese Academy of SciencesShanghai 200031China CAS Key Laboratory of Computational Biology Shanghai Institute of Nutrition and HealthUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghai 200031China Shanghai Center for Brain Science and Brain-Inspired Intelligence Technology Shanghai 201210China

Genomic imprinting can lead to allele-specific expression(ASE),where one allele is preferentially expressed more than the *** in genomic imprinting or ASE genes have been widely observed across various neurological disorders,notably autism spectrum disorder(ASD).In this study,we crossed rhesus cynomolgus monkeys to produce hybrid monkeys and established a framework to evaluate their allele-specific gene expression patterns using the parental genomes as a *** proof-of-concept analysis of the hybrid monkeys identified 353 genes with allele-biased expression in the brain,enabling us to determine the chromosomal locations of ASE ***,we confirmed a significant enrichment of ASE genes associated with neuropsychiatric disorders,including ASD,highlighting the potential of hybrid monkey models in advancing our understanding of genomic imprinting.

关键词： imprinting allele chromosomal

Cloning of a gene-edited macaque monkey by somatic cell nuclear transfer

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National Science Review 2019年第1期6卷 101-108页

作者： Zhen Liu Yijun Cai Zhaodi Liao Yuting Xu Yan Wang Zhanyang Wang Xiaoyu Jiang Yuzhuo Li Yong Lu yanhong Nie Xiaotong Zhang Chunyang Li Xinyan bian Mu-ming Poo Hung-Chun Chang Qiang Sun Institute of Neuroscience CAS Center for Excellence in Brain Science and Intelligence Technology CAS Key Laboratory of Primate Neurobiology State Key Laboratory of Neuroscience Chinese Academy of Sciences Shanghai Research Center for Brain Science and Brain-inspired Technology

Cloning of macaque monkeys by somatic cell nucleus transfer(SCNT) allows the generation of monkeys with uniform genetic backgrounds that are useful for the development of non-human primate models of human diseases. Here, we report the feasibility of this approach by SCNT of fibroblasts from a macaque monkey(Macaca fascicularis), in which a core circadian transcription factor BMAL1 was knocked out by clustered regularly interspaced short palindromic repeat/Cas9 gene editing(see accompanying paper).Out of 325 SCNT embryos transferred into 65 surrogate monkeys, we cloned five macaque monkeys with BMAL1 mutations in both alleles without mosaicism, with nuclear genes identical to that of the fibroblast donor monkey. Further peripheral blood m RNA analysis confirmed the complete absence of the wild-type BMAL1 transcript. This study demonstrates that the SCNT approach could be used to generate cloned monkeys from fibroblasts of a young adult monkeys and paves the way for the development of macaque monkey disease models with uniform genetic backgrounds.

关键词： macaque monkey cloning somatic cell nuclear transfer non-human primate models CRISPR/Cas9 gene editing circadian rhythm disorders