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The effects of exercise interventions on brain-derived neurotrophic factor levels in children and adolescents:a meta-analysis

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Neural Regeneration Research 2025年第5期20卷 1513-1520页

作者： Xueyun Shao Longfei He yangyang Liu Physical Education School Shenzhen UniversityShenzhenGuangdong ProvinceChina Shenzhen Institute of Neuroscience ShenzhenGuangdong ProvinceChina

Brain-derived neurotrophic factor is a crucial neurotrophic factor that plays a significant role in brain health. Although the vast majority of meta-analyses have confirmed that exercise interventions can increase brain-derived neurotrophic factor levels in children and adolescents, the effects of specific types of exercise on brain-derived neurotrophic factor levels are still controversial. To address this issue, we used meta-analytic methods to quantitatively evaluate, analyze, and integrate relevant studies. Our goals were to formulate general conclusions regarding the use of exercise interventions, explore the physiological mechanisms by which exercise improves brain health and cognitive ability in children and adolescents, and provide a reliable foundation for follow-up research. We used the Pub Med, Web of Science, Science Direct, Springer, Wiley Online Library, Weipu, Wanfang, and China National Knowledge Infrastructure databases to search for randomized controlled trials examining the influences of exercise interventions on brain-derived neurotrophic factor levels in children and adolescents. The extracted data were analyzed using Review Manager 5.3. According to the inclusion criteria, we assessed randomized controlled trials in which the samples were mainly children and adolescents, and the outcome indicators were measured before and after the intervention. We excluded animal experiments, studies that lacked a control group, and those that did not report quantitative results. The mean difference(MD;before versus after intervention) was used to evaluate the effect of exercise on brain-derived neurotrophic factor levels in children and adolescents. Overall, 531 participants(60 children and 471 adolescents, 10.9–16.1 years) were included from 13 randomized controlled trials. Heterogeneity was evaluated using the Q statistic and I^(2) test provided by Review Manager software. The meta-analysis showed that there was no heterogeneity among the studies(P = 0.67,

关键词： adolescents brain-derived neurotrophic factor children exercise meta-analysis randomized controlled trials

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3-11 Transmission Electron Microscopy Investigations of Bubble Formation along GBs in He-implanted Polycrystalline SiC

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IMP & HIRFL Annual Report 2014年第1期 100-101页

作者： Li Bingsheng Wang Zhiguang du yangyang Wei Kongfang Yao Cunfeng Sun Jianrong Zhang Hongpeng 不详

Because of the low cross-section for neutron capture and its excellent structural, chemical and mechanicalstability, silicon carbide (SiC) is an important material with application in the development of nuclear energyand waste technologies. The (n,) nuclear reaction inevitably introduces numerous He in SiC. Because of the lowsolubility of He atoms in SiC, a certain concentration of He atoms that are trapped in the matrix in the formof helium-vacancy clusters would form bubbles upon annealing. He bubbles would perhaps lead to degradation ofmaterial properties. Especially, He bubbles along Grain boundaries (GBs) can cause embrittlement by intergranularfracture, as usually observed in metals. Therefore, it is important to investigate the nucleation and growth of Hebubbles along GBs in He-implanted SiC.

关键词： Electron Microscopy Investigations

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走向细化:宋代的乡村组织与乡村治理

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清华大学学报（哲学社会科学版） 2021年第3期36卷 13-24,205页

作者：廖寅杜洋洋河北大学宋史研究中心保定071002 浙江大学人文高等研究院

随着社会从分散走向整体和中央集权的强化,国家介入乡村社会的力度逐渐增强,人地关联管理走向精细化,原来适合分散型社会的大幅员乡里制不再为国家所需,必然让位于适合整体性社会的幅员更小的乡村组织,都保制于是应运而生。在人地关联... 详细信息

随着社会从分散走向整体和中央集权的强化,国家介入乡村社会的力度逐渐增强,人地关联管理走向精细化,原来适合分散型社会的大幅员乡里制不再为国家所需,必然让位于适合整体性社会的幅员更小的乡村组织,都保制于是应运而生。在人地关联管理走向精细化的过程中,保甲、经界、地图三合一起到了关键的推动作用。从乡里到都保,从乡官到乡役,在收乡权于政府的同时,新的更多体现国家意志的乡村权威体制取代了传统的乡村权威体制。宋代乡村社会缺乏门阀、乡绅一类明显的支配阶层,这种独特的时代环境为国家力量深入乡村社会、改变乡村社会提供了绝佳的机会。这也导致宋代国家对于乡村的权威,既超越汉唐,亦为后来的元明清所不及。

关键词：宋代乡村组织乡村治理精细化进程

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情绪面孔搜索效率的脑形态学基础

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科学通报 2016年第34期61卷 3698-3707页

作者：王勇超杜杨杨毕泰勇邱江西南大学心理学部认知与人格教育部重点实验室重庆400715

人类对面孔加工的特异性和有效性已被许多研究所证实,快速感知他人的情绪表情对个体的社会行为有重要作用.前人研究表明,情绪面孔的加工显著快于中性面孔,神经影像学研究也表明杏仁核等脑区对情绪面孔表现出显著的激活.然而,多种情绪面... 详细信息

人类对面孔加工的特异性和有效性已被许多研究所证实,快速感知他人的情绪表情对个体的社会行为有重要作用.前人研究表明,情绪面孔的加工显著快于中性面孔,神经影像学研究也表明杏仁核等脑区对情绪面孔表现出显著的激活.然而,多种情绪面孔加工的优势效应的共同的大脑结构基础还没有得到揭示.本研究使用视觉搜索范式,验证了情绪面孔搜索显著快于中性面孔搜索.通过计算搜索情绪面孔和搜索中性面孔的拟合直线的斜率之差,得到每个被试高兴和恐惧面孔搜索的效率,发现两种情绪面孔搜索效率呈现显著的正相关.在此基础上,结合核磁共振影像基于体素的形态学分析,研究情绪面孔加工搜索效率的个体差异的大脑结构基础.结果发现,高兴和恐惧的情绪面孔的搜索效率均与右侧后扣带和左侧顶上小叶区域的灰质体积呈显著的相关.这表明,个体对不同的情绪面孔表情的敏感性的个体差异可能有共同的脑结构基础.

关键词：情绪面孔加工视觉搜索基于体素的形态学分析灰质体积右侧后扣带左侧顶上小叶

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3 - 4 Microstructural and Nano-hardness Changes in He Irradiated 6H-SiC

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IMP & HIRFL Annual Report 2013年第1期 65-66页

作者： Li Bingsheng Wang Zhiguang du yangyang Sun Jianrong Cui Minghuan Wei Kongfang Yao Cunfeng

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Enantio-divergent C–H borylation with two different ligands from a single chiral source

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Science China Chemistry 2025年第1期68卷 226-232页

作者： Rongrong du Senmiao Xu State Key Laboratory for Oxo Synthesis and Selective Oxidation Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000China College of Material Chemistry and Chemical Engineering Key Laboratory of Organosilicon Chemistry and Material TechnologyMinistry of EducationHangzhou Normal UniversityHangzhou 311121China University of Chinese Academy of Sciences Beijing 100049China

Reported here is an iridium-catalyzed enantio-divergent C(sp^(3))–H borylation ofα-gem-dimethyl groups of trifluoromethyl ketone-derived hydrazones to construct a series of acyclic all-carbon quaternary stereocenters with a high level of chiral *** different chiral bidentate boryl ligands from a common chiral source not only can switch the enantioselectivity but also are complementary in terms of the substrate scope.

关键词： asymmetric catalysis C–H borylation all-carbon quaternary stereocenters synthetic methods

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3 - 3 A Brief Research Related to Fluidized Metals Particles, Particularly as Spallation Target Materials

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IMP & HIRFL Annual Report 2013年第1期 63-65页

作者： Sun Jianrong Wang Zhiguang Pang Lilong Cui Minghuan du yangyang Zhu Yabin Zhang Xueying Wang Fei Li long

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Tuning the ion-dipole interactions between fluoro and carbonyl(EC)by electrolyte design for stable lithium metal batteries

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Chinese Chemical Letters 2025年第1期36卷 579-584页

作者： Guihuang Fang Ying Liu yangyang Feng Ying Pan Hongwei Yang Yongchuan Liu Maoxiang Wu Faculty of Metallurgy and Energy Engineering Kunming University of Science and TechnologyKunming 650093China Key Laboratory of Optoelectronic Materials Chemistry and Physics Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China

Ethylene carbonate(EC)is the conventional and promising solvent to achieve high energy lithium metal ***,the innate low energy level of lowest unoccupied molecular orbital(LUMO)in EC makes it incompatible with lithium metal,causing uncontrolled lithium growth and low Coulombic efficiency(CE).Herein,we introduced bis(2,2,2-trifluoroethyl)carbonate(TFEC),a carbonate with a strong electron-withdrawing effect(-CF_(3)),which enhances the stability of EC at electrode interface by reducing ion-dipole interactions between Li^(+)and *** the interaction between Li and EC weakens,TFEC and more PF_(6)^(-)anions coordinate with Li^(+),promoting the formation of contact ion pairs(CIPs)and aggregates(AGGs),thereby increasing the inorganic composition within the solid electrolyte ***,the distinct solvated sheath structure favors the decomposition of fluorinated solvents and PF_(6)^(-)anions,forming inorganic-rich electrode-electrolyte interfaces(SEI and CEI),thereby ensuring high stability for both the Li anode and high-voltage ***,when applied in the full-cell Li||LiMn_(0.8)Fe_(0.2)PO_(4),it displays consistent cycling performance,exhibiting minimal capacity decay with a retention rate of 62.5%after800 cycles,substantially surpassing that of cells using base electrolytes(29.8%).

关键词： Lithium-ion batteries LiMn_(0.8)Fe_(0.2)PO_(4) High-voltage Solvation structure Ethylene carbonate Bis(2,2,2-trifluoroethyl)carbonate

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The Influence of PbI<sub>2</sub>on Characteristic of Organic-Inorganic Hybrid Perovskite Thin Films

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Modeling and Numerical Simulation of Material Science 2017年第4期7卷 47-57页

作者： Yuze Peng Yuxiang Wu Linlin Tang Juan Li Jian Xu yangyang du Like Huang Hongkun Cai Jian Ni Jianjun Zhang Institute of Photo-Electronics Nankai University The Tianjin Key Laboratory for Optical-Electronic Thin Film Devices and Tech-nology Tianjin China

Organic-inorganic hybrid perovskite materials have attracted significant research efforts because of their outstanding properties. Meanwhile the crystallization of organic-inorganic hybrid perovskite materials can significantly influence the films quality. Here, we research the influence of the characteristics of PbI2 thin film on final perovskite films and the mechanisms of film formation based on the two-step sequential deposition method. We found that the characteristics of PbI2 thin film, such as the grain size, the grain shape, the surface roughness and the film densification, have significant effects on the final perovskite films due to different film crystallization process. According to the analysis on the characteristics of the perovskite films obtained from different PbI2precursor, we suggested that the formation of perovskite film begins from the PbI2 crystals expanding when they are converted to MAPbI3 perovskite by migration of MA+ cations from the grain boundaries.

关键词： Perovskite Film Formation Grain Characteristics

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Self-assembled nanostructured photosensitizer with aggregation-induced emission for enhanced photodynamic anticancer therapy

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Science China Materials 2020年第1期63卷 136-146页

作者： Wenkun Han Song Zhang Rong Deng yangyang du Jingyu Qian Xiaohua Zheng Bin Xu Zhigang Xie Fei Yan Wenjing Tian State Key Laboratory of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchun 130012China State Key Laboratory of Inorganic Synthesis and Preparative Chemistry International Joint Research Laboratory of Nano-Micro Architecture Chemistry(NMAC)International Research Center for Chemistry-Medicine Joint InnovationCollege of ChemistryJilin UniversityChangchun 130012China State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China

Three nanostructured photosensitizers with aggregation-induced emission(AIE) characteristics based on2,3-bis(4?-(diphenylamino)-[1,1?-biphenyl]-4-yl) fumaronitrile(BDBF) were prepared for image-guided photodynamic therapy(PDT). BDBF was encapsulated with Pluronic F-127(F127) to form usual spherical nanoparticles(F127@BDBF NPs) with a red fluorescence emission and 9.8% fluorescence quantum yield(FQY). Moreover, BDBF self-assembled into nanorods(BDBF NRs) in water. Compared with F127@BDBF NPs, BDBF NRs exhibited stronger orange fluorescence with a higher FQY of 23.3% and similar singlet oxygen(1O2) generation capability. BDBF NRs were further modified with F127 to form BDBF@F127 NRs with the same 1O2 generation ability as BDBF NRs. The three nanostructures exhibited a higher 1O2 production capacity than BDBF molecule in dissolved state and favorable stability in an aqueous solution as well as under physiological condition. In vitro photocytotoxicity experiments indicated that the three nanostructures inhibited tumor cell proliferation ***, to construct eligible nanostructures with a high FQY and 1O2 generation ability, simple self-assembly can serve as a valuable method to prepare photosensitizers with enhanced PDT.

关键词： aggregation-induced emission photosensitizer nanorods photodynamic therapy

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