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Rationale of a Cross-Sectional Descriptive Study on Associated Factors and Prognosis Maternal-Fetal Links to Early Onset Preeclampsia at the University Clinics of Kinshasa, DR Congo

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Open Journal of Obstetrics and Gynecology 2023年第11期13卷 1869-1880页

作者： Muela Andy Mbangama Mbuwe Yves Bozeme Mushengezi Dieudonné Sengeyi Mbenza Benjamin Longo Vangu Roland Vangu Sado Jacques Mokassa Mbaya Eloge Ilunga Sendeke Patrick Mogwo yangbo sonia sabanga Feruzi Michel Mangala Kebela Thésée Kogomba Malu Merveille Kinanga Departement of Gynecology and Obstetrics Univeristy Clinics of Kinshasa Kinshasa The Democratic Republic of Congo Departement of Internal Medicine Univeristy Clinics of Kinshasa Kinshasa The Democratic Republic of Congo Departement of Gynecology and Obstetrics Univeristy of President Joseph KASA-VUBU Boma The Democratic Republic of Congo Pharmaceutical Sciences Faculty University of Kinshasa Kinshasa The Democratic Republic of Congo

Background: Preeclampsia (PE) is one of the forms of hypertensive diseases that occur during pregnancy. Early-onset preeclampsia (EOP), which occurred before 34 weeks, proved to be the deadliest. Indeed, it is characterized by a poor maternal and fetal prognosis. EOP has a disparate incidence in the world varying between 0.9% and 31%. Several risks factors are associated with the occurrence of EOP, which is responsible of several adverse obstetrical outcomes. Complications can affect up to 85% of pregnant women with EOP, especially when EOP appears very early, before 28 or even 25 weeks’ gestation. Objectives: To determine frequency of EOP at the University Clinics of Kinshasa, to describe sociodemographic and clinical characteristics of pregnant women with EOP and to identify its risks factors and its association adverse obstetrical outcomes. Methods: The study will be a cross-sectional analytical study in University Clinics of Kinshasa from January 2016 to December 2022. The minimal size will be 119. Our study population will consist of pregnant women who consult for antenatal best care and are neonates in our Clinic. Result will be presented as percentage proportion. Comparison and proportion means between groups will be made using Student’s test and Pearson’s chi-square test, respectively. Our test will be statistically significant for a p-value ≤ than less 0.05. Data will be collected and analysed anonymously and confidentiality. Conclusion: We believe that our study should enable us to identify profile of gestational carriers at risk of EOP in our environment, as well as prognosis associated with this entity, with a view to arousing particular interest in EOP.

关键词： Early-Onset Preeclampsia Associated Factors Prognosis University Clinics of Kinshasa

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