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Magnetic resonance imaging assessment of the lateral geniculate nucleus volume and height in patients with glaucoma:a Meta-analysis

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International Journal of Ophthalmology(English edition) 2023年第4期16卷 638-644页

作者： Hai-Jian Hu Yi-Li Chang yang-yang dai Yu-Lin Yu Xu Zhang Affiliated Eye Hospital of Nanchang University Jiangxi Research Institute of Ophthalmology and Visual ScienceJiangxi Clinical Research Center for Ophthalmic DiseaseJiangxi Branch of National Clinical Research Center for Ocular DiseasesNanchang 330006Jiangxi ProvinceChina

AIM:To evaluate the lateral geniculate nucleus(LGN)volume and height using magnetic resonance imaging(MRI)in glaucoma ***:Literatures retrieval was carried out through Pub Med,Web of Science,Embase,and Cochrane *** that compared the volume and height of LGN in glaucoma patients with that in control subjects were *** volume and height of LGN were extracted from the included *** Review Manager 5.4.1 software was used for the ***:This Meta-analysis included 10 crosssectional studies,including the eyes of 223 glaucoma patients and 185 healthy *** with the control subjects,the volume and height of LGN in glaucoma patients measured by MRI were significantly reduced{-29.13 mm3,95%[confidence interval(CI):-44.82 to-13.43,P=0.0003;-0.61 mm,95%CI:-0.78 to-0.44,P<0.00001,respectively]}.Subgroup analysis demonstrated that the differences of LGN volume and height between glaucoma patients and control subjects in the older group were smaller than that in the younger group,and LGN volume decreased with the increase of glaucoma ***:The results demonstrate that the volume and height of LGN are decreased in glaucoma patients,and LGN volume can be considered a parameter of glaucoma severity.

关键词： magnetic resonance imaging lateral geniculate nucleus glaucoma Meta-analysis

Emerging trends in the selective production of value-added aromatics

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Science China Chemistry 2025年第1期68卷 15-20页

作者： Yuchao Wu Houliang dai Weisheng yang Yaxing Li Lichen Liu Petrochemical Research Institute Company Limited China National Petroleum Corporation Engineering Research Center of Advanced Rare Earth Materials Department of Chemistry Tsinghua University

1 Introduction Aromatics (mainly benzene, toluene, and xylenes, BTX) are essential intermediates in the chemical industry. They are employed in the synthesis of a broad spectrum of chemicals and materials, e.g., various polymers, plastics, resins, solvents, dyes, pharmaceuticals [1]. The manufacturing pathway of BTX mainly includes petroleum reforming of naphtha, coal-to-aromatics, methanol-to-aromatics [2].

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Multiphysics simulation and optimization of the in-situ beneficiation process of ilmenite minerals from lunar regolith

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Science China Earth Sciences 2025年第1期68卷 195-207页

作者： Peng ZHANG Xin LIU Guanghui LIU Wei dai Hanzhe yang Haibo ZHENG Zhi WANG Ran NIU Yifan BAI yang ZHANG Chengbao LIU Ge yang Junwei yang Guang ZHANG Technology and Engineering Center for Space Utilization Chinese Academy of Sciences Beijing Hegong Simulation Co. Ltd

The exploration and utilization of lunar resources have become the major objectives of future lunar exploration missions. The classified collection and processing of lunar minerals is the basic prerequisite for the in-situ exploration and utilization of lunar resources. In this study, we propose a scheme for in-situ separation of magnetic minerals from lunar soils using the dry magnetic separation method. The scheme can realize the purpose of separating magnetic minerals from lunar regolith by altering the motion trajectory of lunar regolith particles with different magnetic properties. Detailed modeling of the dry magnetic separation device is conducted, and the three-dimensional distribution of magnetic parameters is calculated and analyzed. Based on the characterization and analysis of the Chang E-5's samples, the morphologies and physical parameters of lunar regolith particles are modeled and simulated. A discrete element simulation of the motion process of lunar regolith particles under multi-physical field conditions is performed, and the influences of key parameters on the beneficiation performance of lunar magnetic minerals are investigated. Our results indicate that optimal separation and beneficiation of lunar regolith particles can be achieved under specific conditions of magnetic field strength and drum speed. Additionally, we analyze the effects of lunar weak gravity conditions and the charged nature of lunar particles on the beneficiation process, showing that these factors can obviously enhance the beneficiation process of lunar ilmenites. This study demonstrates the feasibility of using the dry magnetic separation method for the beneficiation of magnetic minerals from lunar regolith, providing a theoretical basis for the scientific tasks of collecting, processing, and utilizing lunar mineral resources.

关键词： Lunar regolith In-situ resource utilization Magnetic separation Classified sampling

Oxidation Resistance of Form-stable Hightemperature Phase Change Thermal Energy Storage Materials Doped by Impregnated Graphite

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 1-12页

作者： LI Baorang dai Jianhuan ZHANG Wei LIU Xiangchen yang Liu School of Energy Power and Mechanical Engineering North China Electric Power UniversityBeijing 102206China School of Ener-gy and Environment Southeast UniversityNanjing 210096China

We adopted the solution impregnation route with aluminum dihydrogen phosphate solution as liquid medium for effective surface modification on graphite *** mass ratio of graphite to Al(H_(2)PO_(4))_(3) changed from 0.5:1 to 4:1,and the impregnation time changed from 1 to 7 *** typical composite phase change thermal storage materials doped with the as-treated graphite were fabricated using form-stable *** investigate the oxidation and anti-oxidation behavior of the impregnated graphite at high temperatures,the samples were put into a muffle furnace for a cyclic heat *** on SEM,EDS,DSC techniques,analyses on the impregnated technique suggested an optimized processing conditions of a 3 h impregnation time with the ratio of graphite:Al(H_(2)PO_(4))_(3) as 1:3 for graphite impregnation *** investigations on high-temperature phase change heat storage materials doped by the treated graphite suggested excellent oxidation resistance and thermal cycling performance.

关键词： phase change materials graphite impregnation method oxidation,sintering thermal analysis

SYNTHESIS AND ELECTRONIC SPECTRA OF RUTNENIUM(Ⅱ)-1,1'-BIISOQUINOLINE COMPLEXES

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Chinese Chemical Letters 1993年第11期4卷 1021-1024页

作者： Rui yang yang, Li Xin dai Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032

l,l'-biisoquinoline can coordinate with ruthenfum(Ⅱ) to form a new series of mononuclear complexes and the electronic absorption of these complexes were measured and reasonably assigned.

关键词： Ru SYNTHESIS AND ELECTRONIC SPECTRA OF RUTNENIUM BIISOQUINOLINE COMPLEXES

Glutamatergic CYLD deletion leads to aberrant excitatory activity in the basolateral amygdala:association with enhanced cued fear expression

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Neural Regeneration Research 2025年第11期20卷 3259-3272页

作者： Huidong Li Faqin Li Zhaoyi Chen Erwen Wu Xiaoxi dai Danni Li Haojie An Shiyi Zeng Chunyan Wang Li yang Cheng Long School of Life Sciences South China Normal UniversityGuangzhouGuangdong ProvinceChina School of Life Sciences Guangzhou UniversityGuangzhouGuangdong ProvinceChina Guangdong Provincial Key Laboratory of Major Obstetric Diseases The Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina South China Normal University-Panyu Central Hospital Joint Laboratory of Translational Medical Research Panyu Central HospitalGuangzhouGuangdong ProvinceChina

Neuronal activity,synaptic transmission,and molecular changes in the basolateral amygdala play critical roles in fear ***(CYLD)is a deubiquitinase that negatively regulates the nuclear factor kappa-B *** is well studied in non-neuronal cells,yet underinvestigated in the brain,where it is highly *** studies have shown involvement of CYLD in the remodeling of glutamatergic synapses,neuroinflammation,fear memory,and anxiety-and autism-like ***,the precise role of CYLD in glutamatergic neurons is largely ***,we first proposed involvement of CYLD in cued fear *** next constructed transgenic model mice with specific deletion of Cyld from glutamatergic *** results show that glutamatergic CYLD deficiency exaggerated the expression of cued fear in only male ***,loss of CYLD in glutamatergic neurons resulted in enhanced neuronal activation,impaired excitatory synaptic transmission,and altered levels of glutamate receptors accompanied by over-activation of microglia in the basolateral amygdala of male ***,our study suggests a critical role of glutamatergic CYLD in maintaining normal neuronal,synaptic,and microglial *** may contribute,at least in part,to cued fear expression.

关键词： basolateral amygdala cued fear expression cylindromatosis deubiquitinase glutamate receptor 1 glutamatergic neuron microglial activation N-methyl-D-aspartate receptor 1 neuronal activation synaptic transmission

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谱图数据库预处理KDD算法研究

计算机工程与应用 2001年第19期37卷 67-69页

作者：杨家红杨格花戴瑜兴湖南师范大学电子工程系长沙410081

针对谱图数据库的特性,在利用数据库知识发现(KDD)技术对谱图数据库进行数据预处理过程中,利用面向属性的归纳法对数据属性间的相关性进行分析,Multi_AdaBoost算法进行聚类分析和统计方法对Beynon表进行审核等方面进行了研究,这样,对质... 详细信息

针对谱图数据库的特性,在利用数据库知识发现(KDD)技术对谱图数据库进行数据预处理过程中,利用面向属性的归纳法对数据属性间的相关性进行分析,Multi_AdaBoost算法进行聚类分析和统计方法对Beynon表进行审核等方面进行了研究,这样,对质谱库有了更进一步的认识,为构建质谱智能解析系统的知识库和质谱解析的智能化打下了良好的基础。

关键词：预处理 KDD算法谱图数据库知识发现聚类分析

Enhancing the performance of the absorber of Cu2ZnSn（S， Se）4 photovoltaic materials by doping Cd2+

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Optoelectronics Letters 2025年

作者： yang Shuqi XUE Yuming dai Hongli WANG Luoxin ZHANG Haiwei BAI Xin Institute of New Energy Intelligence Equipment， School of Integrated Circuit Science and Engineering， Tianjin University of Technology

Cationic doping is considered to be an effective way to improve the efficiency of Cu2ZnSn（S，Se）4（CZTSSe） photovoltaic materials. To improve the quality of the absorption layer of the crystal film， CZTSSe film was doped with some Cd to change the ratio of Cd and Zn in the precursor solution. XRD， Raman， SEM， UV-Vis spectroscopy， and other results showed that Cd successfully replaced Zn in the crystal lattice during post-selenization. The formation of harmful Zn-related defects was reduced， the grain size and crystallinity of the films were significantly increased， and the photoelectric properties of the films such as crystal quality and structural morphology were improved. As the Cd/（Cd+Zn） ratio increased from 0 to 0.35， the band gap of CZCTSSe decreased to 1.02eV. When Cd/（Cd+Zn）=0.25， the crystallinity and grain size reached the best value， and the film surface was smooth and dense， which inhibited the formation of the second phase on the surface of *** theoretical basis and experimental results showed that proper Cd doping can promote the growth of grain， so that compact CZCTSSe films with larger grain sizes and fewer holes could be prepared.

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Can patients with mild non-neoplastic lesions diagnosed at baseline screening be safely exempt from surveillance: evidence from multicenter community-based cohorts

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Science China Life Sciences 2025年第1期68卷 263-271页

作者： Siyi He Zhiyi Zhang Guohui Song Zhenhai Wang Chunyun dai Shipeng Yan Kun Jiang Bingbing Song He Li Maomao Cao Dianqin Sun Fan yang Xinxin Yan Shaoli Zhang Yi Teng Qianru Li Changfa Xia Wanqing Chen Office of Cancer Screening National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical College Department of Gastroenterology Gansu Wuwei Tumor Hospital Cixian Cancer Institute Linzhou Cancer Hospital Center for Disease Control and Prevention of Sheyang County Department of Cancer Prevention and Control Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of MedicineCentral South University Luoshan Center for Disease Control and Prevention Office for Cancer Control and Research Affiliated Cancer Hospital of Harbin Medical University

Surveillance recommendations for gastric cancer（GC） in current guidelines focused on advanced precancerous lesions and were based on precise diagnosis of severity/extent of baseline lesions. We aimed to develop a less endoscopy-related equipment-dependent risk-stratification tool, and assessed whether mild-precursor-lesion patients can be safely exempt from surveillance. In the multicenter communitybased cohort, 75,051 participants receiving baseline endoscopy were enrolled during 2015–2017 and followed-up until 2021. Cumulative incidence rates（CIRs） of GC for precancerous-conditions were calculated by Kaplan-Meier method and compared by Log-rank tests. Mixedeffects Cox regression models were used to detect potential factors for progression towards GC. A risk score was calculated as counts of selected factors. An independent cohort, including 26,586 participants was used for external validation. During a median follow-up of 6.25 years, CIRs of GC were 0.302%, 0.436%, and 4.756% for normal group, non-neoplastic（atrophic gastritis/intestinal metaplasia） and neoplastic lesions（low-grade/high-grade dysplasia）, respectively(Ptrend<0.001). Four predictors, including male, ≥60 years, smoking, and limited vegetable consumption, were selected for risk-stratification. High-risk patients（≥3 risk factors） with non-neoplastic lesions showed higher GC risks（adjusted HR=7.73, 95%CI: 4.29–13.92）, and their four-year CIR reached the one-year CIR of neoplastic lesions. Further categorizing non-neoplastic lesions by histological grade, both patients with moderate-to-severe lesions（aHR=3.07, 95%CI: 1.67–5.64） and high-risk patients with mild lesions（aHR=7.29, 95%CI: 3.58–14.86） showed higher risks. Consistent trends were observed in validation cohort. High-risk mild-precursor-lesion patients should receive surveillance within 3–5 years after baseline screening. Our study provides evidence on supplementing current guideline recommendations.

关键词： stomach neoplasms precancerous conditions cancer screening cumulative incidence risk stratification