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Electrochemical Hydrogen Charging on Corrosion Behavior of Ti-6Al-4V Alloy in Artificial Seawater

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Chinese Journal of Mechanical Engineering 2024年第1期37卷 296-308页

作者： Yanxin qiao Yue Qin Huiling Zhou Lanlan yang Xiaojing Wang Zhengbin Wang Zhenguang Liu Jiasheng Zou School of Materials Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China yangzhou Changelight Co. LtdYangzhou 225012China CAS Key Laboratory of Nuclear Materials and Safety Assessment Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China

This study employs advanced electrochemical and surface characterization techniques to investigate the impact of electrochemical hydrogen charging on the corrosion behavior and surface film of the Ti-6Al-4V alloy.The findings revealed the formation ofγ-TiH andδ-TiH_(2) hydrides in the alloy after hydrogen charging.Prolonging hydrogen charging resulted in more significant degradation of the alloy microstructure,leading to deteriorated protectiveness of the surface film.This trend was further confirmed by the electrochemical measurements,which showed that the corrosion resistance of the alloy progressively worsened as the hydrogen charging time was increased.Consequently,this work provides valuable insights into the mechanisms underlying the corrosion of Ti-6Al-4V alloy under hydrogen charging conditions.

关键词： Ti-6Al-4V alloy Hydrogen charging Electrochemical corrosion Passive film

Impact of antagonist peptides and chelators on the diagnostic performance of PET/CT using gallium-68 labeled somatostatin receptor antagonists

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Journal of Pancreatology 2022年第3期5卷 15-39页

作者： Haiqun Xing Wenjia Zhu Yuejuan Cheng qiao yang Ru Jia Hong Zhao Chunmei Bai Li Huo Wenming Wu Nuclear Medicine Department State Key Laboratory of Complex Severe and Rare DiseasesCenter for Rare Diseases ResearchBeijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear MedicinePeking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijingChina Department of Oncology Peking Union Medical College HospitalBeijingChina Department of Gastrointestinal Oncology the fifth Medical CenterGeneral Hospital of PLABeijingChina Department of Hepatobiliary Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of General Surgery Peking Union Medical College HospitalPeking Union Medical CollegeChinese Academy of Medical SciencesBeijingChina

Objective:Different SSTR2 antagonists have been developed.This study aims to evaluate the impact of different peptides and chelators on the diagnostic performance of SSTR2 antagonists in well-differentiated NETs.Methods:In this prospective study,participants were equally randomized into two arms:Arm A,participants would undergo a whole-body 68Ga-NODAGA-LM3 PET/CT scan on the 1st day and 68Ga-DOTA-LM3 PET/CT scan on the 2nd day;Arm B,participants would undergo a whole-body 68Ga-NODAGA-LM3 PET/CT scan on the 1st day and 68Ga-NODAGA-JR11 PET/CT scan on the 2nd day.Biodistribution in normal organs,lesion detection ability,and tumor uptakes were compared within each Arm.Results:A total of 40 participants(age,49.5±13.4,21 men),20 in each arm,were recruited in the study.In Arm A,68Ga-DOTA-LM3 showed lower background.However,the lesion detection ability(overall lesion detected,445 versus 548,P=0.005)and the lesion uptake(overall lesions SUVmax,19.8±17.2 versus 35.3±28.8,P<0.001)was significantly lower than those of 68Ga-NODAGA-LM3.In Arm B,both 68Ga-NODAGA-LM3 and 68Ga-NODAGA-JR11 showed similar biodistribution and lesion uptake(SUVmax,28.5±23.8 versus 25.0±20.0,P<0.001)despite minor differences.The lesion detection ability was the same between these two tracers(overall lesion detected,503 versus 503).Conclusions:The diagnostic performance of SSTR2 antagonists was sensitive to chelators.Both 68Ga-NODAGA-LM3 and 68Ga-NODAGA-JR11 outperformed 68Ga-DOTA-LM3 with higher lesion uptake and detection ability,of which 68Ga-NODAGA-LM3 had marginally but significantly higher lesion uptake.

关键词： Somatostatin receptor antagonist 68Ga-NODAGA-LM3 68Ga-DOTA-LM3 68Ga-NODAGA-JR11 neuroendocrine tumor

International Communication of Acupuncture and Moxibustion Popular in the West

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Chinese Medicine and Culture 2024年第2期7卷 119-127页

作者： qiao Huijun LIU Jingyuan HU Weiguo yang Yuyang Secretariat of World Federation of Acupuncture-Moxibustion Societies Beijing 100061China China Academy of Chinese Medical Sciences Beijing 100700China Department of Acupuncture and Moxibustion Swiss University of Traditional Chinese MedicineBad Zurzach 5330Switzerland

With the development of traditional Chinese medicine(TCM)acupuncture and moxibustion,research on acupuncture and moxibustion in the Western world is deepening.The concept of acupuncture and moxibustion popular in the West is formed.By investigating the localization of acupuncture and moxibustion in the Western world,this paper introduces several kinds of acupuncture and moxibustion popular in the West and concludes the spread of acupuncture and moxibustion popular in the West through hospitals and clinics,academic works,social organizations,education,and training.This paper provides a global vision developing domestic acupuncture and moxibustion and promoting academic prosperity and technical progress of world acupuncture and moxibustion system.

关键词： Acupuncture and moxibustion International communication Western world

A visible-light-assisted Pd/TiO_(2)gas sensor with carbon nanotubes electrodes for trace formaldehyde detection

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Rare Metals 2024年第1期43卷 257-266页

作者： Can Liu qiao-qiao Zou Bin Liu Yong Zhang School of Physics and Optoelectronics Xiangtan UniversityXiangtan 411105China Hunan Institute of Advanced Sensing and Information Technology Xiangtan UniversityXiangtan 411105China School of Materials Science and Engineering Xiangtan UniversityXiangtan 411105China

Owing to the ppb-level detection standard toward the toxic and harmful gas,the detection of trace gases has become an important subject in the field of indoor environment management.However,the traditional resistive gas sensors hardly meet the requirement due to the weak signal generated by trace gas molecules that are difficult to capture.Herein,a visible-light-assisted Pd/TiO_(2)gas sensor is proposed to endow the effective detection of trace formaldehyde(HCHO)gas without heating temperature.Benefiting from the enhanced photocatalytic properties of TiO_(2)by Pd decoration,the visible-light-assisted Pd/TiO_(2)gas sensor can detect the HCHO gas as low as80×10^(–9)at room temperature.The successful preparation of nanoscale TiO_(2)sensing layer is facilitated by the ultrathin carbon nanotube interdigital electrode in the gas sensor,which avoids the discontinuity of the sensing layer caused by the excessive thickness of the traditional metal electrode.In addition,the whole preparation process of the Pd/TiO_(2)gas sensor with carbon nanotube electrodes is compatible with mainstream CMOS fabrication technology,which is expected to realize the batch fabrication and micro-integrated application of gas sensors.It is expected that our work can provide a new strategy for the batch preparation of high-performance trace HCHO gas sensors and their future applications in portable electronic devices such as smartphones.

关键词： Visible-light-assisted gas sensor Pd/TiO_(2) Trace HCHO detection Carbon nanotubes electrodes

Recovering from prolonged cardiac arrest induced by electric shock:A case report

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World Journal of Clinical Cases 2024年第13期12卷 2248-2253页

作者： Jian Zhang Yan-Ru qiao Ya-Dong yang Guo-Zheng Pan Chong-Qing Lv Department of General Surgery Shengli Oilfield Central HospitalDongying 257000Shandong ProvinceChina Department of Emergency Medicine Shengli Oilfield Central HospitalDongying 257000Shandong ProvinceChina

BACKGROUND Cardiac arrest(CA)induced by electric shock is a rare occurrence,particularly in cases of prolonged CA.Currently,there is limited literature on similar incidents,and we present a relevant case report.CASE SUMMARY A 27-year-old Asian male man,experiencing respiratory CA due to electric shock,was successfully restored to sinus rhythm after 50 min of cardiopulmonary resuscitation and 8 electrical defibrillation sessions.In the subsequent stages,the patient received multiple organ function protection measures,leading to a successful recovery and eventual discharge from the hospital.CONCLUSION Prolonging resuscitation time can enhance the chances of survival for patients,this study provide valuable insights into the management of electric shock-induced CA.

关键词： Electric shock Cardiac arrest Prolonged cardiopulmonary resuscitation Cerebral resuscitation Case report

Late Cenozoic uplift of the Liupan Mountains:Evidence from the Neogene loess deposits

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Science China Earth Sciences 2024年第5期67卷 1480-1488页

作者： Zhilin HE Yansong qiao Zhengtang GUO Chaoqin CHEN Long CHEN yang FU Ye yang Yanxia LIANG Xinru LIN Guoqiao XIAO Tao ZHAN Key Laboratory of Cenozoic Geology and Environment Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China Institute of Geomechanics Chinese Academy of Geological SciencesBeijing 100081China CAS Center for Excellence in Life and Paleoenvironment Beijing 100044China University of Chinese Academy of Sciences Beijing 100049China Institute of Ecological Geology Survey and Research of Heilongjiang Province Harbin 150030China School of Geography and Information Engineering China University of GeosciencesWuhan 430078China School of Earth Sciences China University of GeosciencesWuhan 430074China Natural Resources Survey Institute of Heilongjiang Province Harbin 150036China

The Liupan Mountains,one of the important mountain ranges in western China,are located on the boundary between the northeastern Tibetan Plateau and the Ordos Block.The uplift history of the Liupan Mountains remains controversial.Loess deposits are good tracers of regional tectonic and geomorphic changes,because loess is sensitive to erosion and the formation and preservation of loess requires relatively flat highlands and relatively stable tectonic environments.We investigated the distribution of Neogene loess deposits on the western piedmont of the Liupan Mountains and examined a near-continuous loess section(Nanping section)on the piedmont alluvial highlands.Correlation of magnetic susceptibility stratigraphy with the QA-ⅠMiocene loess sequence dates this 56-m section covering the interval from~8.1 to 6.2 Ma.The lower boundary age of this section,together with previously reported Zhuanglang red clay(sand-gravel layers with intercalated loess during~9–8 Ma and near-continuous loess during~8–4.8 Ma)and Chaona red clay(~8.1–2.58 Ma),indicates that the Liupan Mountains were uplifted in the late Miocene(~9–8 Ma)and basically formed by~8 Ma,attesting to no intense mountain building since that time.In addition,based on the information from the Zhuanglang core and the QA-Ⅰsection,we infer that sizable parts of the Liupan Mountains were uplifted during the late Oligocene–early Miocene and did not experience intense uplift during~22–9 Ma.

关键词： Liupan Mountains Mountain building Neogene Loess Chinese Loess Plateau Late Miocene Late Oligocene–early Miocene

Crossroads:Pathogenic role and therapeutic targets of neutrophil extracellular traps in rheumatoid arthritis

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BIOCELL 2024年第1期48卷 9-19页

作者： yang LI JIAN LIU YUEDI HU CHENGZHI CONG YIMING CHEN qiao ZHOU Department of Rheumatology The First Affiliated Hospital of Anhui University of Chinese MedicineHefei230031China First Clinical Medical School Anhui University of Chinese MedicineHefei230031China Institute of Rheumatology Anhui Academy of Chinese MedicineHefei230031China

Rheumatoid arthritis(RA)is a prevalent autoimmune disease whose main features include chronic synovial inflammation,bone destruction,and joint degeneration.Neutrophils are often considered to be the first responders to inflammation and are a key presence in the inflammatory milieu of RA.Neutrophil extracellular traps(NETs),a meshwork of DNA-histone complexes and proteins released by activated neutrophils,are widely involved in the pathophysiology of autoimmune diseases,especially RA,in addition to playing a key role in the neutrophil innate immune response.NETs have been found to be an important source of citrullinated autoantigen antibodies and inflammatory factor release,which can activate RA synovial fibroblasts(FLS)and cause joint damage.This article reviews the role of NETs in the pathophysiology of RA,demonstrating the application of multiple molecules with various therapies,with a view to informing the discovery and development of novel biomarkers and therapeutic targets for RA.

关键词： Rheumatoid arthritis Neutrophil extracellular traps Review

GRP75 of CHO Cells Responds to Ribosylation

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生物化学与生物物理进展 2014年第11期41卷 1191-1192页

作者： LU yang HE Rong-qiao Institute of Biophysics Chinese Academy of SciencesBeijing 100101 China

GRP75 of CHO Cells Responds to Ribosylation

关键词： GRP75 CHO 生物化学生物物理

Alphaherpesvirus-vectored vaccines against animal diseases: Current progress

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Journal of Integrative Agriculture 2020年第8期19卷 1928-1940页

作者： HU yang WANG Ming-shu CHENG An-chun JIA Ren-yong yang qiao WU Ying LIU Ma-feng ZHAO Xin-xin ZHU De-kang CHEN Shun ZHANG Sha-qiu WANG Yin GAO Qun OU Xu-min MAO Sai WEN Xing-jian XU Zhi-wen CHEN Zheng-li ZHU Ling LUO Qi-hui TIAN Bin PAN Lei-chang Mujeeb Ur REHMAN LIU Yun-ya YU Yan-ling ZHANG Ling CHEN Xiao-yue Institute of Preventive Veterinary Medicine Sichuan Agricultural UniversityChengdu 611130P.R.China Key Laboratory of Animal Disease and Human Health of Sichuan Province Sichuan Agricultural UniversityChengdu 611130P.R.China Avian Disease Research Center College of Veterinary MedicineSichuan Agricultural UniversityChengdu 611130P.R.China

Recombinant virus-vectored vaccines are novel agents that can effectively activate specific and nonspecific immunity,are multivalent and multieffective,and have high safety ratings.Animal alphaherpesviruses have a large genome,contain multiple nonessential regions that do not affect viral replication and are capable of accepting the insertion of an exogenous gene and expressing the antigen protein.Furthermore,animal alphaherpesviruses have a wide host spectrum,can replicate in the host and continuously stimulate the animal to produce immunity to the corresponding pathogen,thus making them ideal carriers for recombinant virus-vectored vaccines.With the development of gene-editing technology,recombinant viruses capable of expressing foreign genes can be constructed by various methods.Currently,studies on recombinant virusvectored vaccines constructed based on animal alphaherpesviruses have involved poultry,pigs,cattle,sheep,and companion animals.Studies have shown that the construction of recombinant animal alphaherpesviruses enables the acquisition of immunity to multiple diseases.This article mainly summarizes the current progress on animal alphaherpesvirus-vectored vaccines,aiming to provide reference for the development of new animal alphaherpesvirus-vectored vaccines.

关键词： recombinant vectored-vaccine recombinant alphaherpesviruses immunity gene-editing exogenous gene