检索结果-南通市图书馆

Cellular adaptation to hypoxia and p53 transcription regulation

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2009年第5期10卷 404-410页

作者： yang zhao xue-qun chen ji-zeng du Lab of Neurobiology and Physiology Department of Physiology School of Medicine Zhejiang University Hangzhou 310058 China

Tumor suppressor p53 is the most frequently mutated gene in human tumors. Meanwhile, under stress conditions, p53 also acts as a transcription factor, regulating the expression of a series of target genes to maintain the integrity of genome. The target genes of p53 can be classified into genes regulating cell cycle arrest, genes involved in apoptosis, and genes inhibiting angiogenesis, p53 protein contains a transactivation domain, a sequence-specific DNA binding domain, a tetramerization domain, a non-specific DNA binding domain that recognizes damaged DNA, and a later identified proline-rich domain. Under stress, p53 proteins accumulate and are activated through two mechanisms. One, involving ataxia telangiectasia-mutated protein （ATM）, is that the interaction between p53 and its down-regulation factor murine double minute 2 （MDM2） decreases, leading to p53 phosphorylation on Serl 5, as determined by the post-translational mechanism; the other holds that p53 increases and is activated through the binding of ribosomal protein L26 （RPL26） or nucleolin to p53 mRNA 5＇ untranslated region （UTR）, regulating p53 translation. Under hypoxia, p53 decreases transactivation and increases transrepression. The mutations outside the DNA binding domain of p53 also contribute to tumor progress, so further studies on p53 should also be focused on this direction. The subter- ranean blind mole rat Spalax in Israel is a good model for hypoxia-adaptation. The p53 of Spalax mutated in residue 172 and residue 207 from arginine to lysine, conferring it the ability to survive hypoxic conditions. This model indicates that p53 acts as a master gene of diversity formation during evolution.

关键词： p53 Transcription factor Hypoxia Adaptation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

High-altitude hypoxia induces disorders of the brain- endocrine-immune network through activation of corticotropin-releasing factor and its type- 1 receptors

引用

中国应用生理学杂志 2012年第6期28卷 481-487页

作者： xue-qun chen Fan-ping KONG yang zhao ji-zeng du Division of Neurobiology and Physiology Department of Basic Medical Sciences School of Medicine Zhejiang University Hangzhou 310058 Key Laboratory of Medical Neurobiology of the Ministry of Health Hangzhou 310058 Key Laboratory of Medical Neurobiology of Zhejiang Province Hangzhou 310058 China

High-altitude hypoxia can induce physiological dysfunction and mountain sickness,but the underlying mechanism is not fully ***-releasing factor(CRF) and CRF type-1 receptors(CRFR1) are members of the CRF family and the essential controllers of the physiological activity of the hypothalamo-pituitary-adrenal(HPA) axis and modulators of endocrine and behavioral activity in response to various *** have previously found that high-altitude hypoxia induces disorders of the brain-endocrine-immune network through activation of CRF and CRFR1 in the brain and periphery that include activation of the HPA axis in a time-and dose-dependent manner,impaired or improved learning and memory,and anxiety-like behavioral ***,hypoxia induces dysfunctions of the hypothalamo-pituitary-endocrine and immune systems,including suppression of growth and development,as well as inhibition of reproductive,metabolic and immune *** contrast,the small mammals that live on the Qinghai-Tibet Plateau alpine meadow display low responsiveness to extreme high-altitudehypoxia challenge,suggesting well-acclimatized genes and a physiological strategy that developed during evolution through interactions between the genes and *** the findings provide evidence for understanding the neuroendocrine mechanisms of hypoxia-induced physiological *** review extends these findings.

关键词：促肾上腺皮质激素释放因子内分泌系统功能紊乱激活时间免疫网络高海拔缺氧大脑

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Einstein Probe discovery of EP240408a: A peculiar X-ray transient with an intermediate timescale

引用

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 222-240页

作者： Wenda Zhang Weimin Yuan Zhixing Ling Yong chen Nanda Rea Arne Rau Zhiming Cai Huaqing cheng Francesco Coti Zelati Lixin Dai jingwei Hu Shumei jia Chichuan jin Dongyue Li Paul O’Brien Rongfeng Shen Xinwen Shu Shengli Sun Xiaojin Sun Xiaofeng Wang Lei yang Bing Zhang chen Zhang Shuang-Nan Zhang Yonghe Zhang jie An David Buckley Alexis Coleiro Bertrand Cordier Liming Dou Rob Eyles-Ferris Zhou Fan Hua Feng Shaoyu Fu Johan P.U.Fynbo Lluis Galbany Saurabh W.Jha Shuaiqing jiang Albert Kong Erik Kuulkers Weihua Lei Wenxiong Li Bifang Liu Mingjun Liu Xing Liu Yuan Liu Zhu Liu Chandreyee Maitra Alessio Marino Itumeleng Monageng Kirpal Nandra Jeremy Sanders Roberto Soria Lian Tao Junfeng Wang Song Wang Tinggui Wang Zhongxiang Wang Qingwen Wu xuefeng Wu Dong Xu Yanjun Xu Suijian xue Yongquan xue Zijian Zhang Zipei Zhu Hu Zou Congying Bao Fansheng chen Houlei chen Tianxiang chen Wei chen Yehai chen Yifan chen chenzhou Cui Weiwei Cui Yanfeng Dai Dongwei Fan Ju Guan Dawei Han Dongjie Hou Haibo Hu Maohai Huang jia Huo Zhenqing jia Bowen jiang Ge jin chengkui Li Junfei Li Longhui Li Maoshun Li Wei Li Zhengda Li Tianying Lian Congzhan Liu Heyang Liu Huaqiu Liu Fangjun Lu Laidan Luo jia Ma Xuan Mao Haiwu Pan Xin Pan Liming Song Hui Sun Yunyin Tan Qingjun Tang Yihan Tao Hao Wang Juan Wang Lei Wang Wenxin Wang Yilong Wang Yusa Wang Qinyu Wu Haitao Xu jingjing Xu Xinpeng Xu Yunfei Xu zhao Xu Changbin xue Yulong xue Ailiang Yan Haonan yang Xiongtao yang Yanji yang Juan Zhang Mo Zhang Wenjie Zhang Zhen Zhang Zhen Zhang Ziliang Zhang Donghua zhao Haisheng zhao Xiaofan zhao Zijian zhao Hongyan Zhou Yilin Zhou Yuxuan Zhu Zhencai Zhu National Astronomical Observatories Chinese Academy of Sciences School of Astronomy and Space Sciences University of Chinese Academy of Sciences Key Laboratory of Particle Astrophysics Institute of High Energy Physics Chinese Academy of Sciences Institute of Space Sciences (ICE) CSIC Institut d’Estudis Espacials de Catalunya (IEEC) Max Planck Institute for Extraterrestrial Physics Innovation Academy for Microsatellites Chinese Academy of Sciences Department of Physics University of Hong Kong School of Physics and Astronomy University of Leicester School of Physics and Astronomy Sun Yat-sen University Department of Physics Anhui Normal University Shanghai Institute of Technical Physics Chinese Academy of Sciences Physics Department Tsinghua University Nevada Center for Astrophysics University of Nevada Las Vegas Department of Physics and Astronomy University of Nevada Las Vegas South African Astronomical Observatory Department of Astronomy University of Cape Town Department of Physics University of the Free State Université Paris Cité CNRS Astroparticule et Cosmologie Université Paris Cité CEA Paris-Saclay IRFU/DAp-AIM Department of Astronomy Guangzhou University Cosmic Dawn Center (DAWN) Niels Bohr Institute University of Copenhagen Department of Physics and Astronomy Rutgers the State University of New Jersey Institute for Cosmic Ray Research The University of Tokyo ESA/ESTEC Department of Astronomy School of Physics Huazhong University of Science and Technology INAF-Osservatorio Astrofisico di Torino Sydney Institute for Astronomy School of Physics The University of Sydney Department of Astronomy Xiamen University Institute for Frontiers in Astronomy and Astrophysics Beijing Normal University Department of Astronomy University of Science and Technology School of Astronomy and Space Sciences University of Science and Technology of China Institute of Deep Space Sciences Deep Space Exploration Laboratory Department of Astronomy School of Physics and Astronomy Yunnan University Shanghai Astronomical Observatory Chi

We report the discovery of a peculiar X-ray transient,EP240408a,by Einstein Probe （EP） and follow-up studies made with EP,Swift,NICER,GROND,ATCA and other ground-based multiwavelength *** new transient was first detected with Wide-field X-ray Telescope （WXT） on board EP on April 8th,2024,manifested in an intense yet brief X-ray flare lasting for *** flare reached a peak flux of 3.9×10-9erg cm-2s-1in 0.5-4 ke V,～300 times brighter than the underlying X-ray emission detected throughout the *** and more precise follow-up observations by EP/FXT,Swift and NICER confirmed the finding of this new *** X-ray spectrum is non-thermal in 0.5-10 ke V,with a power-law photon index varying *** X-ray light curve shows a plateau lasting for ～4 d,followed by a steep decay till becoming undetectable ～10 d after the initial *** on its temporal property and constraints from previous EP observations,an unusual timescale in the range of 7-23 d is found for EP240408a,which is intermediate between the commonly found fast and long-term *** counterparts have been found in optical and near-infrared,with the earliest observation at 17 h after the initial X-ray detection,suggestive of intrinsically weak emission in these *** demonstrate that the remarkable properties of EP240408a are inconsistent with any of the transient types known so far,by comparison with,in particular,jetted tidal disruption events,gamma-ray bursts,X-ray binaries and fast blue optical *** nature of EP240408a thus remains an *** suggest that EP240408a may represent a new type of transients with intermediate timescales of the order of～10 *** detection and follow-ups of more of such objects are essential for revealing their origin.

关键词： X-ray transients ${\bm~{Einstein~~Probe}}$

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

全谷物及杂豆添加量在小鼠与人体间剂量换算分析

引用

食品科学 2025年第2期46卷 118-125页

作者：支莉朱益清赵亮星陈睿赵卿宇王超薛勇沈群国家粮食产业(青稞深加工)技术创新中心国家粮油标准测试研究中心中国农业大学食品科学与营养工程学院北京100083

适量摄入全谷物及杂豆可以改善糖代谢和脂代谢,但摄入量过高可能产生不利影响。由于缺乏相应的换算关系,小鼠饲料中的摄入量无法直接作为人群摄入量的参考。本文介绍小鼠饲料中常见的全谷物及杂豆的添加量,并通过等效系数法、比表面积... 详细信息

适量摄入全谷物及杂豆可以改善糖代谢和脂代谢,但摄入量过高可能产生不利影响。由于缺乏相应的换算关系,小鼠饲料中的摄入量无法直接作为人群摄入量的参考。本文介绍小鼠饲料中常见的全谷物及杂豆的添加量,并通过等效系数法、比表面积法、体型系数法、食物比重法、体表面积指数法、能量换算法和营养素换算法探讨了小鼠饲料中全谷物及杂豆添加量与人群膳食推荐量之间的剂量效应关系。研究表明,当人群全谷物及杂豆推荐摄入量为50~150 g时,相当于在每日进食量为3 g的小鼠饲料中添加5%~50%的全谷物及杂豆。对于小鼠而言,饲料中全谷物及杂豆的添加量超过50%可能存在过量摄入的风险。本研究为未来建立全谷物及杂豆在小鼠饲料添加量与人群推荐摄入量之间的换算关系提供了重要参考。

关键词：剂量换算全谷物杂豆体表面积

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

High-precision magnetic field measurement system based on a coherent population trapping magnetometer onboard the SATech-01 satellite

引用

Science China Technological Sciences 2025年

作者： Hongbo xue Wei SONG Haoran zhao Yiteng ZHANG Shanzhi YE jindong WANG Ran TAO Peng SANG Keli chen Xingzi BI Bingjun chenG Bin ZHOU Yongliang xue Yingying TANG Liu LIU jinsong LI Xiaocheng ZHU Baoquan LI jinguo LIU Wen chen Xiaofeng ZHANG Yonghe ZHANG Lei LI State Key Laboratory of Space Weather National Space Science Center Chinese Academy of Sciences Key Laboratory of Solar Activity and Space Weather National Space Science Center Chinese Academy of Sciences Key Laboratory of Electronics and Information Technology for Space Systems National Space Science Center Chinese Academy of Sciences State Key Laboratory of Robotics Shenyang Institute of Automation Chinese Academy of Sciences Innovation Academy for Microsatellites Chinese Academy of Sciences

On July 27, 2022, a high-precision system for measuring the magnetic field based on a coherent population trapping magnetometer（referred to as the CPT system） was launched onboard the Space Advanced Technology demonstration satellite（SATech-01） by a ZK-1A rocket. The payload comprises a scalar coherent population trapping magnetometer（CPTM）, triaxial anisotropic magnetoresistance magnetometer（AMRM）, and nano star tracker mounted on a non-magnetic telescopic tubular mast. This configuration enables synchronized measurement of scalar and vector geomagnetic fields, as well as the attitude,making the payload with its compact sensors suitable for applications on miniature satellite platforms. On November 7, 2022,the novel telescopic tubular mast was deployed in orbit, extending to a length of 5.28 m. The CPTM, an absolute scalar magnetometer with an omnidirectional sensor, is the first China-developed quantum/atomic magnetometer successfully operating in space. In orbit, the CPTM has sensitivity of ～10 pT/Hz1/2and can automatically operate under complex magnetic field variations. The difference between the scalar fields obtained using the CPTM and CHAOS model has a mean deviation of–3.73 n T and a standard deviation of 26.11 nT（1σ）, without on-orbit calibration or correction. The miniaturized AMRM has a sensitivity of ～0.3 n T/Hz1/2and maintains stable and reliable operation in orbit. The low-power and miniaturized nano star tracker has a measurement uncertainty of 14.23″（1σ） in orbit. The mission has realized the on-orbit technical verification of the integrated and synchronized detection of the vector magnetic field and attitude and fully validated the system's performance,automation level, and reliability.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Enhanced subacute ischemic stroke treatment via multistage drug delivery system design for combination therapy

引用

Science China Chemistry 2025年

作者： Xihan Xu Juan-Juan Li jiamin Li Hui-Yan Zhang Yilin Qi Bing-Sen Shi Tianqi Li Shan-Shan Su Weitao zhao Chang chen Zhongying Gong Huiyu Liu Ke-Rang Wang Dong-Sheng Guo xue xue State Key Laboratory of Medicinal Chemical Biology College of Pharmacy Nankai University College of Chemistry State Key Laboratory of Elemento-Organic Chemistry Key Laboratory of Functional Polymer Materials (Ministry of Education) Frontiers Science Center for New Organic Matter Collaborative Innovation Center of Chemical Science and EngineeringNankai University College of Chemistry and Materials Science State Key Laboratory of New Pharmaceutical Preparations and Excipients Key Laboratory of Medicinal Chemistry and Molecular Diagnosis (Ministry of Education) Key Laboratory of Chemical Biology of Hebei Province Hebei Research Center of the Basic Discipline of Synthetic Chemistry Hebei University Department of Neurology Tianjin First Central Hospital School of Medicine Nankai University Beijing Advanced Innovation Center for Soft Matter Science and Engineering State Key Laboratory of Organic-Inorganic Composites Beijing Laboratory of Biomedical Materials Bionanomaterials & Translational Engineering Laboratory Beijing Key Laboratory of BioprocessBeijing University of Chemical Technology

The management of acute ischemic stroke remains challenging due to its abrupt onset and the narrow treatment window,resulting in high rates of disability and *** therapy for neuroprotection and neurorepair strategies provided new hopes for subacute stroke *** we designed a multistage nanodelivery system that matches the unique microenvironment of the subacute phase of stroke,which utilizes calixarene as a building block to effectively load the neuroprotective drug *** calixarene is designed with glycosidic linkages targeting the glucose transporter 1 (GLUT1)on the blood-brain barrier (BBB) and azo bonds that are responsive to hypoxic ***,the decomposed calixarene molecules themselves possess intrinsic bio-activation to modulate inflammatory responses,achieving a multistage therapeutic approach that transitions from targeting to release and finally to *** approach combines anti-inflammation and neuroprotection,providing a multi-level treatment *** system was validated in a rat model of permanent middle cerebral artery occlusion (pMCAO),demonstrating that intravenous administration of the nanodelivery system repairs brain damage and improves motor function 24 h post-pMCAO *** work offers a precise and integrative strategy for stroke patients missing the acute therapy window to improve functional recovery and enhance the effect of comprehensive treatment.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Mechanism of improved magnetizing roasting of siderite–hematite iron ore using a synergistic CO–H2 mixture

引用

Journal of Iron and Steel Research International 2020年第1期27卷 12-21页

作者： Qiang zhao ji-lai xue Wen chen School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China Changsha Research Institute of Mining and Metallurgy Co. Ltd.Changsha 410083HunanChina

A fluidized-bed magnetizing roasting-magnetic separation process was selected to treat this type of *** transformations and microstructural changes in the product resulting from magnetizing roasting under different reducing gases(CO,H2,CO+H2)were clarified by vibrating sample magnetometry,X-ray diffraction,scanning electron microscopy,and energy-dispersive X-ray *** results indicated that the conversion ratio and saturation magnetization of samples roasted in a mixed gas of CO and H2 were higher than those of samples produced under CO or H2 *** indicated that synergy of the combined CO and H2 gas had a positive effect on the fluidized-bed magnetizing roasting *** mechanism and kinetics of the improved magnetizing roasting of a siderite-hematite iron ore mixture under this synergistic CO-H2 system were investigated under isothermal *** results indicated that the apparent activation energies of the reactions of the iron oxides decreased from 37.7 and 17.9 to 15.9 kJ/moI when the roasting atmosphere was changed from pure H2 or CO to a gas mixture of CO and H2,*** mixed CO-H2 gas promoted the conversion ratio of hematite and siderite to magnetite,thereby improving the conversion ratio in the fluidized-bed magnetizing roasting process.

关键词： Siderite Hematite Mixed iron ore Fluidized-bed magnetizing roasting Kinetics Magnetite

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of temperature-gradient-induced damage of zirconia metering nozzles

引用

International Journal of Minerals,Metallurgy and Materials 2017年第9期24卷 999-1003页

作者： Liang zhao qun-hu xue College of Materials and Mineral Resources Xi’an University of Architecture and TechnologyXi’an 710055China Shaanxi Techno-institute of Recycling Economy Xi’an 710055China

The effects of temperature-gradient-induced damage of zirconia metering nozzles were investigated through analysis of the phase composition and microstructure of nozzle samples. The analysis was carried out using X-ray diffraction and scanning electron microscopy after the samples were subjected to a heat treatment based on the temperatures of the affected, transition, and original layers of zirconia metering nozzles during the continuous casting of steel. The results showed that, after heat treatment at 1540, 1410, or 1300A degrees C for a dwell time of 5 h, the monoclinic zirconia phase was gradually stabilized with increasing heat-treatment temperature. Moreover, a transformation to the cubic zirconia phase occurred, accompanied by grain growth, which illustrates that the temperature gradient in zirconia metering nozzles affects the mineral composition and microstructure of the nozzles and accelerates damage, thereby deteriorating the quality and service life of the nozzles.

关键词： temperature gradient zirconia metering nozzles mineral composition microstructure damage mechanism

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synthesis and field emission properties of carbon nanotube films modified with amorphous carbon nanoparticles by a simple electrodeposition method

引用

Chinese Chemical Letters 2014年第2期25卷 375-379页

作者： Juan yang Xing-Bin Yan jiang-Tao chen Dong-Fei Sun qun-ji xue Laboratory of Clean Energy Chemistry and Materials Lanzhou Institute of Chemical Physics.Chinese Academy of Science State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of Sciences

Amorphous carbon nanoparticles （a-CNPs） on a multi-walled carbon nanotube （MWCNT） film, deposited on a silicon substrate, were synthesized using an electrodeposition combination from a methanol suspension of polydiallyldimethylammonium chloride-modified MWCNTs. A low-voltage electropho- retic deposition of the MWCNTs and a high-voltage electrochemical deposition of the a-CNPs were carried out to yield homogenously attached a-CNPs on the surfaces of the MWCNTs, and form a composite film with good adhesion to the substrate. This scalable technology can produce a large area of a-CNP/MWCNT film. And the field emission investigations show that the a-CNP/MWCNT film has turn- on electric field of 3.17 V μm- 1 （at 10 μA cm-2） and threshold field of 4.62 V μm-1 （at 1 mA cm-2）, which are lower than those of the MWCNT film. The a-CNP/MWCNT film can be deposited simply with large areas and may be a promising cathode material applied in field emission displays.

关键词： Carbon nanotube films Amorphous carbon Electrodeposition Field emission

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Estimation of Road Friction Coefficient in Different Road Conditions Based on Vehicle Braking Dynamics

引用

Chinese Journal of Mechanical Engineering 2017年第4期30卷 982-990页

作者： You-qun zhao Hai-Qing Li Fen Lin jian Wang xue-Wu ji College of Energy&Power Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China School of Automotive Engineering Shandong Jiaotong UniversityJinan 250023China State Key Laboratory of Automotive Safety and Energy Tsinghua UniversityBeijing 100084China

The accurate estimation of road friction coeffi- cient in the active safety control system has become increasingly prominent. Most previous studies on road friction estimation have only used vehicle longitudinal or lateral dynamics and often ignored the load transfer, which tends to cause inaccurate of the actual road friction coef- ficient. A novel method considering load transfer of front and rear axles is proposed to estimate road friction coef- ficient based on braking dynamic model of two-wheeled vehicle. Sliding mode control technique is used to build the ideal braking torque controller, which control target is to control the actual wheel slip ratio of front and rear wheels tracking the ideal wheel slip ratio. In order to eliminate the chattering problem of the sliding mode controller, integral switching surface is used to design the sliding mode sur- face. A second order linear extended state observer is designed to observe road friction coefficient based on wheel speed and braking torque of front and rear wheels. The proposed road friction coefficient estimation schemes are evaluated by simulation in ADAMS/Car. The results show that the estimated values can well agree with the actual values in different road conditions. The observer can estimate road friction coefficient exactly in real-time andresist external disturbance. The proposed research provides a novel method to estimate road friction coefficient with strong robustness and more accurate.

关键词： Road friction coefficient Real timeestimation External disturbance Different roadconditions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：