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Decreasing Trends in the Incidence of Age-and Sex-specific Hepatitis A Virus Infection in Hunan Province,China,from 2004-2020:A Joinpoint Analysis

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Biomedical and Environmental Sciences 2022年第11期35卷 1063-1069页

作者： yang rui jun LIU Fu Qiang SHI Xin Ji QIAO Qiao WANG Qian ZANG Shuang Department of Community Nursing School of NursingChina Medical UniversityShenyang 110122LiaoningChina Public Health Emergency Response Office Hunan Provincial Center for Disease Control and PreventionChangsha 410000HunanChina Department of Radiation Oncology The First Hospital of China Medical UniversityShenyang 110122LiaoningChina

Hepatitis A virus(HAV)is transmitted via the fecal-oral route,causing not only self-limited infectious hepatitis,but also epidemics through close personal contact(s).HAV infection is prevalent worldwide,and it is esti... 详细信息

关键词： Hunan milli Joinpoint

Anomalous quality factor evolution of induced transparency in a virtualized coupled-oscillator system

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Science China(Physics,Mechanics & Astronomy) 2025年第1期68卷 144-151页

作者： Yunhan yang Han Jia Tuo Liu Yuzhen yang jun yang Key Laboratory of Noise and Vibration Research Institute of AcousticsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China State Key Laboratory of Acoustics Institute of AcousticsChinese Academy of SciencesBeijing 100190China

The phenomenon of induced transparency,characterized by a high quality(Q)factor,holds significant importance in the fields of high-precision sensing,energy storage and wave *** transparency systems are often constrained by the limited experimentally accessible parameter space and the lack of independent control over intrinsic parameters,thereby hindering advanced research on high-Q *** we propose a virtualized coupled-oscillator system that enables reconfigurable induced transparency in the reflection *** virtually incorporating a pair of coupled oscillators into an individual acoustic meta-atom,we achieve the manipulation of induced transparency in a decoupled,wide-ranging,and elaborate *** the diverse evolutions across the intrinsic parameter space,we show experimentally a counter-intuitive increase in the Q-factor of the transparency window,which is attributed to the enhanced dissipation of the bright ***,a constant group delay at the center frequency is observed accompanying this *** work demonstrates an intriguing platform as well as a novel strategy to engineer high-Q induced transparency phenomenon,and paves the way towards applications in programmable acoustic sensors,filters and slow-wave devices.

关键词： induced transparency acoustic meta-atom high quality-factor scattering programmable intrinsic parameter

Tanreqing Injection Inhibits Activation of NLRP3 Inflammasome in Macrophages Infected with Influenza A Virus by Promoting Mitophagy

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Chinese Journal of Integrative Medicine 2025年第1期31卷 19-27页

作者： LIU Tian-yi HAO Yu MAO Qin ZHOU Na LIU Meng-hua WU jun WANG Yi yang Ming-rui School of Life Sciences Beijing University of Chinese MedicineBeijing102488China Experimental Research Center China Academy of Chinese Medical SciencesBeijing100700China

Objective: To investigate the inhibitory effect of Tanreqing Injection(TRQ) on the activation of nucleotide-binding oligomerization domain-like receptor pyrin domain containing 3(NLRP3) inflammasome in macrophages infected with influenza A virus and the underlying mechanism based on mitophagy pathway. Methods:The inflammatory model of murine macrophage J774A.1 induced by influenza A virus [strain A/Puerto Rico/8/1934(H1N1), PR8] was constructed and treated by TRQ, while the mitochondria-targeted antioxidant Mito-TEMPO and autophagy specific inhibitor 3-methyladenine(3-MA) were used as controls to intensively study the anti-inflammatory mechanism of TRQ based on mitophagy-mitochondrial reactive oxygen species(mt ROS)-NLRP3 inflammasome pathway. The levels of NLRP3, Caspase-1 p20, microtubule-associated protein 1 light chain 3 Ⅱ(LC3Ⅱ) and P62 proteins were measured by Western blot. The release of interleukin-1β(IL-1β) was tested by enzyme linked immunosorbent assay, the mt ROS level was detected by flow cytometry, and the immunofluorescence and co-localization of LC3 and mitochondria were observed under confocal laser scanning microscopy. Results: Similar to the effect of Mito-TEMPO and contrary to the results of 3-MA treatment, TRQ could significantly reduce the expressions of NLRP3, Caspase-1 p20, and autophagy adaptor P62, promote the expression of autophagy marker LC3Ⅱ, enhance the mitochondrial fluorescence intensity, and inhibit the release of mt ROS and IL-1β(all P<0.01).Moreover, LC3 was co-localized with mitochondria, confirming the type of mitophagy. Conclusion: TRQ could reduce the level of mt ROS by promoting mitophagy in macrophages infected with influenza A virus, thus inhibiting the activation of NLRP3 inflammasome and the release of IL-1β, and attenuating the inflammatory response.

关键词： Tanreqing Injection influenza virus anti-inflammation mitophagy nucleotide-binding oligomerization domain-like receptor pyrin domain containing 3 inflammasome Chinese medicine

Boron shielding design for neutron and gamma detectors of a pulsed neutron tool

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Nuclear Science and Techniques 2025年第1期36卷 115-126页

作者： Xin-yang Wang jun-Yan Chen Qiong Zhang University of Electronic Science and Technology of China Chengdu 611731China

Shielding materials are critical for downhole pulsed neutron tool design because they directly influence the accuracy of formation measurements.A well-designed shield configuration ensures that the response of the tool is maximally representative of the formation without being affected by the tool and borehole *** study investigated the effects of boron-containing materials on neutron and gamma detectors based on a newly designed logging-while-drilling tool that is currently undergoing *** the boron content increased,the ability to absorb thermal neutrons increased *** simulation,it was proven that boron carbide(B_(4)C)can be used as an effective boron shielding material for thermal neutrons,and is therefore employed in this *** shield against thermal neutrons migrating from the mud pipes,the optimal shielding thicknesses for the near-and far-neutron detectors were determined to be 5 and 4 *** a porosity of 25 p.u.,near-neutron sensitivity exhibited a 5.6%***,to shield the capture gamma generated by thermal neutrons once they enter the tool from the mud pipe and formation,internal and external shields for the gamma detector were *** results show that the internal shield requires a boron content of 75%,whereas the external shield has a thickness of 14.2 mm thickness and a boron content of 25%to minimize the tool effect.

关键词： Nuclear well logging Pulsed neutron tool Boron shielding

Increased contribution of microbial necromass to soil organic carbon in solar farms on the Tibetan Plateau

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Journal of Mountain Science 2025年第1期22卷 184-197页

作者： ZHANG Xiyu ZHOU jun CHEN yang FAN Jianrong Institute of Mountain Hazards and Environment Chinese Academy of SciencesChengdu 610299China

Solar farms have been rapidly expanding on the Qinghai-Tibetan ***,the effects of photovoltaic arrays on the contribution of microbial necromass carbon(MNC)to soil organic carbon(SOC),along with the underlying mechanisms,remain *** address this,we collected soil samples from the top 20 cm in under-panel,inter-panel and control plots at five solar farms constructed between 2012 and 2014 in the dry Yarlung Tsangpo and Lhasa River valleys on the Qinghai-Tibetan *** determined SOC,fungal and bacterial necromass and relevant soil *** found that the concentration of MNC in the under-panel plots(3.93±0.79 mg g-1)was significantly higher compared to the control plots(2.28±0.79 mg g-1)across all five solar *** proportion of MNC to SOC in the under-panel plots(34.7±2.4%)was also significantly higher than that in the control plots(27.5±1.4%).Specifically,the contribution of fungal necromass to SOC in the under-panel plots(26.4±2.2%)was significantly larger than that in the control plots(19.7±1.6%),while the increase in the bacterial necromass proportion was *** least squares structural equation modeling(PLS-SEM)indicated a significant and positive effect of increased soil moisture in the under-panel plots on the proportion of fungal necromass to *** results highlight that beyond their economic benefits,solar farms in the arid regions on the Qinghai-Tibetan Plateau can enhance soil C sequestration by improving soil moisture and promoting microbial necromass accumulation.

关键词： Photovoltaic power station Fungal necromass Bacterial necromass Microbial residues Yarlung Tsangpo Arid river valley

Combination of ultrasonic lithotripsy system and video-assisted retroperitoneal debridement in treatment of laterally located pancreatic walled-off necrosis

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Hepatobiliary & Pancreatic Diseases International 2025年第1期24卷 104-107页

作者： Bei Lu jun-Jie Yin Jing-rui Wang Xiao Xu yang Cai Department of Hepato-Pancreato-Biliary Surgery Affiliated Hangzhou First People’s HospitalWestlake University School of MedicineHangzhou 310006China

Acute necrotizing pancreatitis(ANP)is a critical type of acute pancreatitis(AP)[1,2].ANP has high mortality,long-term hospitalization,high cost,and potential morbidity[3,4].Infected or symptomatic necrosis continually requires debridement as the mainstay of treatment when percutaneous drainage fails[5].With the advent of minimally invasive approaches in recent decades,surgical management of pancreatic necrosis has been *** recommend using a step-up approach instead of direct open pancreatic necrosectomy(OPN)[6].Endoscopic drainage and necrosectomy are appropriate for walled-offnecrosis(WON)near the stomach or duodenum[7].Minimal access retroperitoneal pancreatic necrosectomy(MARPN)is a good approach for laterally located WON that is distant from the stomach or duodenum[8].However,these minimally invasive approaches are still not *** repeatedly debridement itself causes ***,large pieces of necrosis are not easy to clear,and blood vessels are difficult to *** of bleeding,gastrointestinal fistula,and pancreatic fistula are still inevitable.

关键词： stomach debridement Acute

Impact of temperature and salinity on fines detachment: AFM measurements and XDLVO theory

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Petroleum Science 2025年第1期22卷 338-347页

作者： Wei-Feng Yuan Yu-Long yang Lu Yuan Ji-rui Hou State Key Laboratory of Petroleum Resources and Engineering China University of Petroleum Unconventional Petroleum Research Institute China University of Petroleum

Fine particle detachment and subsequent migration can lead to severe pore plugging and consequent permeability decline. Therefore, it is crucial to quantify the critical condition when fine particle detachment occurs. The frequently observed deviations or even contradictions between experimental results and theoretical predictions of fines detachment arise from an insufficient understanding of adhesion force that can be highly influenced by salinity and temperature. To clarify the intrinsic influence of salinity and temperature on fines detachment, adhesion forces between carboxyl microspheres and hydrophilic silica substrates in an aqueous medium were measured at various salinities and temperatures using atomic force microscopy(AFM). The AFM-measured adhesion force decreases with increasing salinity or temperature. Trends of mean measured adhesion forces with temperature and salinity were compared with the DLVO and XDLVO theories. DLVO theory captured the trend with temperature via the impact of temperature on electric double layer interactions, whereas XDLVO theory captured the observed trend with salinity via the impact of salinity on the repulsive hydration force. Our results highlight the significance of hydration force in accurately predicting the fate of fines in porous media.

关键词： Adhesion force AFM Temperature Salinity XDLVO Hydration force

A comprehensive review of deactivation and modification of selective catalytic reaction catalysts installed in cement kilns

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Journal of Environmental Sciences 2025年第2期148卷 451-467页

作者： yang Zheng Yi Xing Guoliang Li Jiajia Gao rui Li Qi Liu Tao Yue School of Energy and Environmental Engineering University of Science and Technology BeijingBeijing 100083China State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

After the ultralow emission transformation of coal-fired power plants,cement production became China’s leading industrial emission source of nitrogen *** gas dust contents at the outlet of cement kiln preheaters were as high as 80-100 g/m^(3),and the calcium oxide content in the dust exceeded 60%.Commercial V_(2)O_(5)(-WO3)/TiO_(2) catalysts suitable for coal-fired flue gas suffer from alkaline earth metal Ca poisoning of cement kiln flue *** studies have also identified the poisoning of cement kiln selective catalytic reaction(SCR)catalysts by the heavy metals lead and *** of the poisoning process is the primary basis for analyzing the catalytic *** review summarizes and analyzes the SCR catalytic mechanism and chronicles the research progress concerning this poisoning *** on the catalytic and toxification mechanisms,it can be inferred that improving the anti-poisoning performance of a catalyst enhances its acidity,surface redox performance-active catalytic sites,and shell layer *** data provide support in guiding engineering practice and reducing operating costs of SCR ***,future research directions for SCR denitrification catalysts in the cement industry are *** study provides critical support for the development and optimization of poisoning-resistant SCR denitrification catalysts.

关键词： Cement Flue Gas NH_(3)-SCR CaO Poisoning Mechanism Anti-poisoning Modification

How does Hedgehog signaling participate in the cross-interaction of hormones and testis development?

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BIOCELL 2025年第1期49卷 93-107页

作者： jun-JIE YU WAN-XI yang The Sperm Laboratory College of Life SciencesZhejiang UniversityHangzhou310058China

Hedgehog(HH)signaling has been researched for decades and Hedgehog has 3 homologs:Sonic Hedgehog(Shh),Indian Hedgehog(Ihh),and Desert Hedgehog(Dhh).Dhh is the one involved in male gonad and germ cell *** distribution of molecules in Hedgehog signaling in testis indicated that Hedgehog signaling executes important functions during testis *** patients with Dhh signaling deficiency develop dysgenesis of gonads and hormone production which demands further exploration of gonad HH *** results proved the indispensable roles of HH signaling in gonad and germ cell development and the interaction with *** review evaluates HH functions in the testis and how HH affects and is affected by hormones and provides novel insights about HH signaling to the readers.

关键词： Hedgehog signaling Hormone Testis Leydig cell Gonadal dysgenesis