检索结果-南通市图书馆

Limosilactobacillus mucosae FZJTZ26M3 prevents NAFLD in mice through modulation of lipid metabolism and gut microbiota dysbiosis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2024年第3期13卷 1589-1601页

作者： Danting Dang bowen Li Mengfan Ding RPaul Ross Catherine Stanton Jianxin Zhao Bo yang Wei Chen State Key Laboratory of Food Science and Resources Jiangnan UniversityWuxi 214122China School of Food Science and Technology Jiangnan UniversityWuxi 214122China International Joint Research Center for Probiotics&Gut Health Jiangnan UniversityWuxi 214122China APC Microbiome Ireland University College CorkCork T12 YT20Ireland Teagasc Food Research Centre MooreparkFermoyCork T12 YT20Ireland National Engineering Research Center for Functional Food Jiangnan UniversityWuxi 214122China

Lactobacillus are considered promising therapeutic methods for nonalcoholic fatty liver disease(NAFLD).The effects of two strains of Ltmosilactobacillus mucosae on NAFLD were investigated in this ***-old male C57BL/6J mice were divided into 4 groups(n=8 per group,Control,Model,FZJTZ26M3,FGSYC17L3).*** FZJTZ26M3 reduced the mice 's body weight,liver weight,and adipose tissue weight after 12 weeks of *** to serum analysis,total cholesterol,triacylglycerol,and low-density lipoprotein cholesterol significantly decreased after *** FZJTZ26M3 *** pathology showed that *** FZJTZ26M3 was effective to ameliorate lipid deposition in NAFLD ***,the expression of the gene related to lipid metabolism in the liver and adipose tissue was analyzed,and the results indicated that *** FZJTZ26M3 could alleviate NAFLD by regulating lipid ***,the results of 16S rRNA gene sequencing revealed a drop in the relative abundance of Ruminococcaceae,which is linked to inflammation,but the relative abundance of a potential probiotic Akkermansia significantly increased after *** FZJTZ26M3 ***,*** FZJTZ26M3 could be a candidate to prevent NAFLD.

关键词： Limosilactobacillus mucosae Nonalcoholic fatty liver disease(NAFLD) Probiotic Lipid metabolism Gut microbiota

Method for Detecting Industrial Defects in Intelligent Manufacturing Using Deep Learning

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第1期78卷 1329-1343页

作者： bowen Yu Chunli Xie College of Mechanical and Electrical Engineering Northeast Forestry UniversityHarbin150040China

With the advent of Industry 4.0,marked by a surge in intelligent manufacturing,advanced sensors embedded in smart factories now enable extensive data collection on equipment *** analysis of such data is pivotal for ensuring production safety,a critical factor in monitoring the health status of manufacturing *** defect detection techniques,typically limited to specific scenarios,often require manual feature extraction,leading to inefficiencies and limited versatility in the overall *** research presents an intelligent defect detection methodology that leverages deep learning techniques to automate feature extraction and defect localization *** proposed approach encompasses a suite of components:the high-level feature learning block(HLFLB),the multi-scale feature learning block(MSFLB),and a dynamic adaptive fusion block(DAFB),working in tandem to extract meticulously and synergistically aggregate defect-related characteristics across various scales and hierarchical *** have conducted validation of the proposed method using datasets derived from gearbox and bearing *** empirical outcomes underscore the superior defect detection capability of our *** demonstrates consistently high performance across diverse datasets and possesses the accuracy required to categorize defects,taking into account their specific locations and the extent of damage,proving the method’s effectiveness and reliability in identifying defects in industrial components.

关键词： Industrial defect detection deep learning intelligent manufacturing

Manipulation for degenerative lumbar spondylolisthesis:A systematic review of randomized controlled trials

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Traditional Chinese Medical Sciences 2022年第2期9卷 121-127页

作者： Zhiwei Liu Xiaokuan Qin Kai Sun He Yin Xin Chen bowen yang Xu Wang Xu Wei Liguo Zhu School of Postgraduate Beijing University of Chinese MedicineBeijing100029China Department of Spine Wangjing HospitalChina Academy of Chinese Medical SciencesBeijing100102China Department of Academic Development Wangjing HospitalChina Academy of Chinese Medical SciencesBeijing100102China

Objective: To assess the effectiveness and safety of manipulation intervention for degenerative lumbar spondylolisthesis(DLS).Methods: This is a systematic review and meta-analysis. A full-scale retrieval method was performed until February 1, 2021, including nine databases. The homogeneity of different studies was summarized using the Review Manager. The quality of studies was determined with the Cochrane risk-of-bias *** evidence quality was graded with the Grading of Recommendations, Assessment, Development, and Evaluations ***: A total of 6 studies involving 524 participants were included. The review demonstrated that manipulation has statistically significant improvements for treating DLS according to Japanese Orthopedic Association scores(mean difference, 3.76;95% confidence interval, 2.63 to 4.90;P <.001) and visual analog scale scores(mean difference,-1.50;95% confidence interval,-1.66 to-1.33;P <.001)compared to the control group. One study reported that the difference in the Oswestry Disability Index between the traction group and the combination of manipulation and traction group was statistically significant(P <.05), while another reported that manipulation treatment can significantly improve the lumbar spine rotation angle on X-ray images compared with the baseline data(P <.05). Moreover, the manipulation group(experimental group) had fewer adverse events than the lumbar traction group(control group).Conclusion: Manipulation intervention is more effective and safer for DLS. Nevertheless, large-scale randomized controlled trials are required to confirm the current conclusions.

关键词： Manipulation Degenerative lumbar spondylolisthesis Meta-analysis Japanese orthopedic association Oswestry disability index Visual analog scale Randomized controlled trial

Time-inconsistent stochastic linear-quadratic control problem with indefinite control weight costs

在线全文

学校读者我要写书评

暂无评论

Science China Mathematics 2024年第1期67卷 211-236页

作者： Qi Lü bowen Ma School of Mathematics Sichuan UniversityChengdu 610064China

A time-inconsistent linear-quadratic optimal control problem for stochastic differential equations is *** introduce conditions where the control cost weighting matrix is possibly *** such conditions,we obtain a family of closed-loop equilibrium strategies via multi-person differential *** result extends Yong’s work(2017) in the case of stochastic differential equations,where a unique closed-loop equilibrium strategy can be derived under standard conditions(namely,the control cost weighting matrix is uniformly positive definite,and the other weighting coefficients are positive semidefinite).

关键词： linear-quadratic optimal control problem time-inconsistent cost functional generalized Riccati equation indefinite control weight cost closed-loop equilibrium strategy

在线全文

学校读者我要写书评

暂无评论

和厚朴酚促进肺癌细胞凋亡的分子机制研究

皖南医学院学报 2024年第4期43卷 311-315页

作者： Nishimwe Ange 张凌志孙浚皓彭博远杨博文吴志浩皖南医学院肿瘤微环境研究室安徽芜湖241002 皖南医学院医学生物学教研室安徽芜湖241002

目的:研究和厚朴酚(HNK)对H1299、H460细胞凋亡的影响,并初步探讨其相关分子机制。方法:体外培养非小细胞肺癌(NSCLC)H1299、H460细胞,用不同浓度的HNK处理48 h。采用MTT法检测细胞活力;采用流式细胞术检测细胞凋亡及细胞周期抑制情况;... 详细信息

目的:研究和厚朴酚(HNK)对H1299、H460细胞凋亡的影响,并初步探讨其相关分子机制。方法:体外培养非小细胞肺癌(NSCLC)H1299、H460细胞,用不同浓度的HNK处理48 h。采用MTT法检测细胞活力;采用流式细胞术检测细胞凋亡及细胞周期抑制情况;采用Western blot检测PDZ结合基序的转录共激活因子(TAZ)、聚腺苷二磷酸核糖聚合酶(PARP)、Bcl-2、caspase-3等蛋白的表达量。结果:H1299和H460细胞经HNK处理后,与对照组相比,各浓度组细胞活力均下降且在各处理时间下细胞活力均下降(P<0.05);Western blot结果显示TAZ、Bcl-2蛋白表达量随着HNK浓度的增加而降低;cleaved-caspase3、cleaved-PARP蛋白表达量随着HNK浓度的增加而增加;caspase-3和PARP蛋白表达量随HNK浓度的增加而无明显变化;不同浓度HNK处理后,与阴性对照组相比,细胞凋亡率增加(P<0.05);HNK处理后过表达TAZ,与阴性对照组相比,细胞凋亡率降低(P<0.05)。结论:HNK可以促进NSCLC H1299和H460细胞的凋亡,其机制可能是通过抑制TAZ发挥作用。

关键词：和厚朴酚细胞凋亡 PDZ结合基序的转录共激活因子非小细胞肺癌

Health Effects of Extreme Low Temperatures and Cold Waves on Respiratory Diseases

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2024年第6期37卷 682-685页

作者： Zongrui Liu Yuxia Ma Yuhan Zhao Wanci Wang Pengpeng Qin Jie yang bowen Cheng College of Atmospheric Sciences Key Laboratory of Semi-Arid Climate ChangeMinistry of EducationLanzhou UniversityLanzhou 730000GansuChina Minhe Meteorological Bureau Minhe 810800QinghaiChina

Climate change is the most significant threat to public health and exerts myriad influences on health,including the occurrence of extreme temperature *** have demonstrated that populations will experience significantl... 详细信息

关键词： extreme Effects events.

Design,preparation,application of advanced array structured materials and their action mechanism analyses for high performance lithium-sulfur batteries

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2024年第2期89卷 266-303,I0007页

作者： Nanping Deng Xiaofan Feng Yongbing Jin Zhaozhao Peng yang Feng Ying Tian Yong Liu Lu Gao Weimin Kang bowen Cheng State Key Laboratory of Separation Membranes and Membrane Processes/National Center for International Joint Research on Separation Membranes School of Textile Science and EngineeringTiangong UniversityTianjin 300387China Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) Nankai UniversityTianjin 300071China

Lithium-sulfur battery(LSB)has brought much attention and concern because of high theoretical specific capacity and energy density as one of main competitors for next-generation energy storage *** widely commercial application and development of LSB is mainly hindered by serious“shuttle effect”of lithium polysulfides(Li PSs),slow reaction kinetics,notorious lithium dendrites,*** various structures of LSB materials,array structured materials,possessing the composition of ordered micro units with the same or similar characteristics of each unit,present excellent application potential for various secondary cells due to some merits such as immobilization of active substances,high specific surface area,appropriate pore sizes,easy modification of functional material surface,accommodated huge volume change,enough facilitated transportation for electrons/lithium ions,and special functional groups strongly adsorbing Li *** many novel array structured materials are applied to battery for tackling thorny problems mentioned *** this review,recent progresses and developments on array structured materials applied in LSBs including preparation ways,collaborative structural designs based on array structures,and action mechanism analyses in improving electrochemical performance and safety are ***,we also have detailed discussion for array structured materials in LSBs and constructed the structure-function relationships between array structured materials and battery ***,some directions and prospects about preparation ways,functional modifications,and practical applications of array structured materials in LSBs are *** hope the review can attract more researchers'attention and bring more studying on array structured materials for other secondary batteries including LSB.

关键词： Array structured materials Preparation methods and structural designs Action mechanism analyses Advanced Li-S batteries Excellent electrochemical performances and safety

Synergy effect between tetracycline and Cr(Ⅵ)on combined pollution systems driving biochar-templated Fe_(3)O_(4)@SiO_(2)/TiO_(2)/g-C_(3)N_(4) composites for enhanced removal of pollutants

在线全文

学校读者我要写书评

暂无评论

Biochar 2023年第1期5卷 1-20页

作者： bowen yang Jiawei Dai Yuan Zhao Zhanchao Wang Jingwei Wu Caiya Ji Yuhu Zhang Xiao Pu College of Resource Environment and Tourism Capital Normal UniversityBeijing 100048China School of Chemistry and Chemical Engineering Guangxi UniversityGuangxi 530004China School of Environmental and Safety Engineering Changzhou UniversityChangzhou 213164China Environmental Technology Engineering Co.Ltd Subsidiary of Chinese Research Academy of Environmental Sciences Beijing 100012China

Biochar-coupled Fe_(3)O_(4)@SiO_(2)/TiO_(2)/g-C_(3)N_(4) composites were successfully constructed through simple sol-gel and calcination *** composites efficiently removed high-concentration toxic tetracycline(TC)by means of·OH and·O_(2)^(−),whose removal rate exhibited 91.88%during 3 h,and the degradation rate constant reached up to 0.0068 min^(−1).The excellent performance can be attributed to the high specific surface area,enhanced visible light response,the introduction of magnetic nanoparticles and biochars expediting charge transfer,Z-scheme heterojunction enhancing the spatial separation of photo-generate carriers and,importantly extraordinary adsorption capacity of 147.96 mg g^(−1).Moreover,the composites showed the most excellent efficiency under the calcination temperature of 450℃,and exhibited good stability with tolerance to a wide range of pH and ***,a synergistic photocatalytic effect was discovered in the TC/Cr(Ⅵ)combined pollution systems,resulting in significantly improved removal of Cr(Ⅵ).Besides,the photocatalytic mechanism and degradation path of tetracycline were also *** these findings suggested the as-synthesized catalyst was an excellent photocatalyst for removal of TC/Cr(Ⅵ)-contaminated water.

关键词： Biochar Tetracycline Hexavalent chromium Combined pollution Synergistic photocatalytic effect

Formal Verification of Data Modifications in Cloud Block Storage Based on Separation Logic

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Electronics 2024年第1期33卷 112-127页

作者： bowen ZHANG Zhao JIN Hanpin WANG Yongzhi CAO Key Laboratory of High Confidence Software Technologies (MOE) School of Computer Science Peking University School of Computer and Artificial Intelligence Zhengzhou University School of Computer Science and Cyber Engineering Guangzhou University

Cloud storage is now widely used, but its reliability has always been a major concern. Cloud block storage(CBS) is a famous type of cloud storage. It has the closest architecture to the underlying storage and can provide interfaces for other types. Data modifications in CBS have potential risks such as null reference or data *** verification of these operations can improve the reliability of CBS to some extent. Although separation logic is a mainstream approach to verifying program correctness, the complex architecture of CBS creates some challenges for verifications. This paper develops a proof system based on separation logic for verifying the CBS data modifications. The proof system can represent the CBS architecture, describe the properties of the CBS system state, and specify the behavior of CBS data modifications. Using the interactive verification approach from Coq, the proof system is implemented as a verification tool. With this tool, the paper builds machine-checked proofs for the functional correctness of CBS data modifications. This work can thus analyze the reliability of cloud storage from a formal perspective.

关键词： Cloud computing Behavioral sciences Reliability Formal verification