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某含锌烟尘中性—酸性两段浸出试验

金属矿山 2013年第2期42卷 164-168页

作者：李岩杨丽梅徐政徐瑞王巍北京有色金属研究总院生物冶金国家工程实验室

为回收某废镀锌板炼钢烟尘中以氧化锌为主的锌,对其进行了中性—酸性两段浸出试验。首先通过条件试验确定了中性浸出时的适宜工艺参数为始酸浓度0 g/L、液固比9 mL/g、搅拌强度200 r/min、浸出温度25℃、浸出时间80 min,酸性浸出时的适... 详细信息

为回收某废镀锌板炼钢烟尘中以氧化锌为主的锌,对其进行了中性—酸性两段浸出试验。首先通过条件试验确定了中性浸出时的适宜工艺参数为始酸浓度0 g/L、液固比9 mL/g、搅拌强度200 r/min、浸出温度25℃、浸出时间80 min,酸性浸出时的适宜工艺参数为始酸浓度20 g/L、液固比9 mL/g、搅拌强度500 r/min、浸出温度25℃、浸出时间80 min,然后按所确定的工艺参数进行中性浸出液为产出液、酸性浸出液返回中性浸出作业的闭路流程试验,试验稳定后锌的浸出率达到90.36%,浸出液中锌的含量为10.14 g/L,铁含量仅为0.56 g/L。

关键词：废镀锌钢板含锌烟尘中性-酸性两段浸出浸出终点pH

褪黑素对盐胁迫下香椿幼苗生长及离子吸收和光合作用的影响

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西北植物学报 2019年第12期39卷 2226-2234页

作者：偶春张敏姚侠妹杨丽梅刘宇屈长青阜阳师范大学生物与食品工程学院抗衰老中草药安徽省工程技术研究中心安徽阜阳236037 浙江省农业科学院浙江省植物有害生物防控重点实验室杭州310021 宿迁学院建筑工程学院江苏宿迁223800

以香椿幼苗为材料,采用水培法研究不同浓度褪黑素(0、50、100、200和400μmol/L)对盐(150 mmol/L NaCl)胁迫下香椿幼苗生长指标、矿质元素离子(Na+、K+、Ca2+和Mg2+)含量、净光合速率(Pn)、蒸腾速率(Tr)、气孔导度(Gs)和胞间CO2浓度(Ci... 详细信息

以香椿幼苗为材料,采用水培法研究不同浓度褪黑素(0、50、100、200和400μmol/L)对盐(150 mmol/L NaCl)胁迫下香椿幼苗生长指标、矿质元素离子(Na+、K+、Ca2+和Mg2+)含量、净光合速率(Pn)、蒸腾速率(Tr)、气孔导度(Gs)和胞间CO2浓度(Ci)等光合作用指标的影响,以探究外源物质褪黑素对盐胁迫下香椿幼苗生长和生理的调控作用。结果表明:(1)在盐胁迫条件下,香椿幼苗的生长受到显著抑制,叶绿素含量和Pn显著降低,叶片和根系中Na+含量比对照(CK)显著增加,而K+、Mg2+和Ca2+含量以及离子含量的比值(K+/Na+、Mg2+/Na+和Ca2+/Na+)则明显下降,且丙二醛含量显著增加。(2)施加适宜浓度褪黑素能显著促进盐胁迫下香椿植株生长,降低其叶片和根系中Na+含量,提高其K+、Ca2+、Mg2+含量和离子含量比值以及叶片Pn、Tr、水分利用效率(WUE)和Gs和Ci,但却降低了气孔限制值(Ls)。(3)适宜浓度褪黑素使盐胁迫下香椿植株叶片的丙二醛积累明显下降,叶绿素含量显著上升。研究发现,外施适宜浓度的褪黑素能降低盐胁迫下香椿幼苗叶片和根系内Na+浓度,增加K+、Mg2+和Ca2+浓度,调控植物体内细胞的离子平衡状态,增强对营养元素的吸收,提高光合作用效率,从而提高香椿幼苗对盐胁迫的抗性,并以100μmol/L褪黑素处理的效果最佳。

关键词：香椿盐胁迫褪黑素离子含量光合作用

Lenalidomide regulates the CCL21/CCR7/ERK1/2 axis to inhibit migration and proliferation in diffuse large B-cell lymphoma

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Oncology Research 2025年第1期33卷 199-212页

作者： WEN yang BIN TANG DAN XU WENXIU yang Department of Pathology Guizhou Medical UniversityThe Affiliated Hospital of Guizhou Medical UniversityGuiyang550004China

Background:The prognostic significance of the chemokine receptor CCR7 in diffuse large B-cell lymphoma(DLBCL)has been reported ***,the detailed mechanisms of CCR7 in DLBCL,particularly regarding its interaction with lenalidomide treatment,are not fully ***:Our study utilized bioinformatics approaches to identify hub genes in SU-DHL-2 cell lines treated with lenalidomide compared to control *** data and clinical information from 122 patients with DLBCL were analyzed to assess the correlation of CCR7 and p-ERK1/2 expression with the prognosis of ***,in vitro and in vivo experiments were conducted to clarify the role of CCR7 in the response of DLBCL to lenalidomide ***:Our bioinformatics analysis pinpointed CCR7 as a hub gene in the context of lenalidomide treatment in ***,31.14%and 36.0%(44/122)of DLBCL cases showed positive expression for CCR7 and ERK1/2 respectively,establishing them as independent prognostic factors for adverse outcomes in DLBCL via multivariate Cox regression ***,our studies demonstrated that the external application of the protein CCL21 promoted proliferation,migration,invasion,and activation of the ERK1/2 pathway in SU-DHL-2 and OCI-LY3 cell lines with high levels of CCR7 *** effect was mitigated by CCR7 silencing through siRNA,application of ERK inhibitors,or lenalidomide *** vivo experiments reinforced the efficacy of lenalidomide,significantly reducing tumor growth rate,tumor mass,serum total LDH levels,and expression of CCR7 and p-ERK1/2 in a SUDHL-2 xenograft model in nude mice(p<0.05).Conclusion:Our study clarifies the potential role of the CCL21/CCR7/ERK1/2 axis in the therapeutic effects of lenalidomide in DLBCL treatment.

关键词： CCR7 CCL21 ERK1/2 Lenalidomide Diffuse large B-cell lymphoma(DLBCL)

Reconstructing forest and grassland cover changes in China over the past millennium

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Science China Earth Sciences 2025年第1期68卷 94-110页

作者： Fanneng HE Fan yang Yafei WANG Key Laboratory of Land Surface Pattern and Simulation Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Key Research Institute of Yellow River Civilization and Sustainable Development Henan University University of Chinese Academy of Sciences

Historical forest and grassland cover changes not only are critical indicators for quantifying ecological and environmental change processes but also serve as fundamental data for long-term climate change simulations and terrestrial ecosystem carbon emission assessments. However, because of limitations in historical data, quantitative estimations and spatially gridded reconstructions of these changes remain challenging, necessitating further methodological exploration. This study focused on China's present-day land area over the past millennium, objectively capturing the characteristics and drivers of forest and grassland cover changes. On this basis, using the forest transition theory and the space-for-time substitution method, we depicted the historical deforestation process as an inverted “S” curve and developed a model to reconstruct historical forest area changes based on the functional relationship between the forest area and population size dynamics. Subsequently, a gridded forest allocation model was established on the basis of deforestation tendencies. For the grassland cover, we implemented regionspecific methods, such as the cropland area deduction method and the habitat constraint method, to quantitatively reconstruct historical changes. Consequently, we obtained provincial forest and grassland area changes over the past millennium and mapped 10-km-resolution gridded data of forest and grassland cover. The results indicated the following.(1) The methods developed using population data as a proxy objectively reproduced the spatiotemporal evolution of forest and grassland cover in China over the past millennium. These feasible methods offer a novel pathway for the quantitative reconstruction of historical forest and grassland cover changes.(2) The data indicated that China's forest area generally decreased over the past millennium, characterized by a “decrease-then-increase” pattern. The forest area experienced three distinct phases: a slow decline(AD 1000

关键词： Land use and land cover change Forest Grassland Quantitative reconstruction Gridded reconstruction China historical period

固相萃取-超高效液相色谱-串联质谱法同时测定动物源性食品中多种兽药残留

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食品科学 2017年第12期38卷 266-272页

作者：郝杰姜洁余建龙路勇毛婷孙晓冬杨丽梅北京市食品安全监控和风险评估中心北京100041 沃特世科技有限公司北京100026

利用通过固相萃取法结合超高效液相色谱-串联质谱法建立同时检测猪肉、鱼、虾等动物源性食品中磺胺类、喹诺酮类、糖皮质激素类、大环内酯类、β-受体激动剂类、类固醇激素类、四环素类、青霉素类、氯霉素类、头孢菌素类10大类72种兽药... 详细信息

利用通过固相萃取法结合超高效液相色谱-串联质谱法建立同时检测猪肉、鱼、虾等动物源性食品中磺胺类、喹诺酮类、糖皮质激素类、大环内酯类、β-受体激动剂类、类固醇激素类、四环素类、青霉素类、氯霉素类、头孢菌素类10大类72种兽药残留的分析方法。样品经80%乙腈溶液提取,直接通过不经活化的Prime HLB固相萃取柱进行净化。使用C_(18)色谱柱分离,电喷雾离子源分段多反应监测扫描模式检测,外标法定量。72种兽药定量限为0.5~5μg/kg,各基质中回收率在75.6%~122.3%之间,相对标准偏差为0.6%~10.7%。本方法极大地提高了多残留兽药的检测效率,适用于食品安全突发事件应急处置中多残留兽药的快速分析。

关键词：固相萃取超高效液相色谱-串联质谱法兽药多残留动物源性食品

影响加碘食盐碘含量检测结果准确性的因素分析及改进措施

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中国井矿盐 2014年第5期45卷 36-39页

作者：荀春杨丽梅云南盐化股份有限公司云南昆明650200

在对加碘食盐进行碘含量检测的过程中发现,同一样品由不同的检验员进行检测,检测结果偏差很大,甚至同一检验员在试验条件一致的情况下,检验结果也超出了标准规定的偏差范围。由此造成了检验结果对生产缺乏指导性,严重时直接导致合格产... 详细信息

在对加碘食盐进行碘含量检测的过程中发现,同一样品由不同的检验员进行检测,检测结果偏差很大,甚至同一检验员在试验条件一致的情况下,检验结果也超出了标准规定的偏差范围。由此造成了检验结果对生产缺乏指导性,严重时直接导致合格产品被误判为不合格,不合格产品反而被判合格。本文通过进行系列试验,查找其产生偏差的主要原因,最终找到了影响食盐中碘含量检测结果准确性的主要因素,并针对关键原因提出了相应的改进措施,对更好的指导生产,确保碘盐质量具有重要意义。

关键词：加碘食盐碘含量准确性研究

Deep learning-based end-to-end depth estimation from a single-frame fringe pattern with the FDSUNet++ network

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Optoelectronics Letters 2025年

作者： ZHU Xinjun ZHANG Jialei SONG limei WANG Hongyi TIAN Ruiqin School of Artificial Intelligence， Tiangong University School of Control Science and Engineering， Tiangong University

Recently the depth estimation methods based on deep learning (DL) retains challenging to estimate high-precision in fringe projection structured light three-dimensional (3D) measurement with limited information from a single-frame fringe pattern. In this letter， we proposed a FDSUNet++ convolutional neural network， which consists of a UNet++ base model， an improved squeeze-and-excitation (ISE) block， a Fourier transform (FT) data preprocessing block， and a discrete wavelet transform (DWT) block. The proposed ISE block can improve the ability of feature extraction and the designed FT data preprocessing block preserves the key features of the fringe pattern by Fourier transform. The introduced DWT block reduces the complexity and training cost of the model. By integrating these three blocks into the UNet++ network， it can better achieve depth estimation. Experimental results from two structured light datasets demonstrate that the proposed FDSUNet++ outperforms the state-of-art networks such as UNet， SUNet， R2U-Net， PCTNet and MSUNet++， achieving the best performance in both qualitative and quantitative evaluation.

关键词：

穴位按摩与耳穴压豆对初产妇第二产程疼痛程度及母婴结局的影响

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新中医 2021年第4期53卷 202-205页

作者：戴颖珏杨丽梅嘉善县妇幼保健院浙江嘉善314100

目的:观察在常规护理措施基础上加用穴位按摩与耳穴压豆对初产妇第二产程疼痛程度及母婴结局的影响。方法:将130例拟经阴道分娩的初产妇按随机数字表法分为对照组和观察组各65例。2组均于第二产程采用以自由体位和自主用力为主的分娩方... 详细信息

目的:观察在常规护理措施基础上加用穴位按摩与耳穴压豆对初产妇第二产程疼痛程度及母婴结局的影响。方法:将130例拟经阴道分娩的初产妇按随机数字表法分为对照组和观察组各65例。2组均于第二产程采用以自由体位和自主用力为主的分娩方式,并给予健康宣教、心理护理等措施。观察组加予穴位按摩与耳穴压豆进行干预。记录第二产程时间、分娩方式,评价疼痛程度,统计产后出血、产后尿潴留及产后发热的发生率;评价新生儿阿普加(Apgar)评分,统计新生儿窒息、酸血症的发生率。结果:观察组第二产程时间短于对照组,新生儿Apgar评分高于对照组,差异均有统计学意义(P0.05)。观察组新生儿窒息发生率与酸血症发生率均低于对照组(P<0.05)。结论:在常规护理措施基础上加用穴位按摩与耳穴压豆可缩短初产妇的第二产程,减少产后尿潴留与新生儿窒息、酸血症的发生,提高阴道顺产率,显著改善母婴结局。

关键词：初产妇第二产程疼痛程度穴位按摩耳穴压豆母婴结局新生儿阿普加评分

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Q—T离散度对急性心肌梗死心脏事件的预测

心血管康复医学杂志 2000年第3期9卷 21-22页

作者：杨丽梅王敏莱芜市人民医院干部科山东省莱芜市莱芜市中医院特检科

目的：探讨Ｑ－Ｔ离散度（Ｑ－Ｔｄ）对急性心肌梗死（ＡＭＩ）心脏事件的预测价值。方法：对比分析了６０例正常人与６８例ＡＭＩ患者的Ｑ－Ｔｄ以及与计事件的关系。结果：ＡＭＩ组较对照组Ｑ－Ｔｄ明显延长（Ｐ〈０．０１）。梗死组... 详细信息

目的：探讨Ｑ－Ｔ离散度（Ｑ－Ｔｄ）对急性心肌梗死（ＡＭＩ）心脏事件的预测价值。方法：对比分析了６０例正常人与６８例ＡＭＩ患者的Ｑ－Ｔｄ以及与计事件的关系。结果：ＡＭＩ组较对照组Ｑ－Ｔｄ明显延长（Ｐ〈０．０１）。梗死组患者中事件组与非事件组Ｑ－Ｔｄ相差显著（Ｐ〈０．０１），而在事件组中以猝死者Ｑ－Ｔｄ最长（Ｐ〈０．０１），结论：Ｑ－Ｔｄ对ＡＭＩ心脏事件的发生具有预测价值。

关键词：急性心肌梗死 Q-T离散度预测