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3种仪器检测糖化血红蛋白结果分析

国际检验医学杂志 2014年第19期35卷 2672-2673页

作者：张卫军黄胜起骆连妹李秀娟郑艳芬大连大学附属中山医院检验科辽宁大连116001 江门市中心医院检验科广东江门529070 江门市人民医院检验科广东江门529071

目的比较3种仪器检测糖化血红蛋白的结果。方法分别采用D-10全自动糖化血红蛋白分析仪(离子交换色谱法)、HA-8160全自动糖化血红蛋白分析仪(亲和色谱法)和7170A全自动生化分析仪(免疫比浊法)检测75例全血样本,对检测结果进行方差齐性检... 详细信息

目的比较3种仪器检测糖化血红蛋白的结果。方法分别采用D-10全自动糖化血红蛋白分析仪(离子交换色谱法)、HA-8160全自动糖化血红蛋白分析仪(亲和色谱法)和7170A全自动生化分析仪(免疫比浊法)检测75例全血样本,对检测结果进行方差齐性检验,方差齐后,进行单因素方差分析和相关性分析。结果 D-10全自动糖化血红蛋白分析仪和HA-8160全自动糖化血红蛋白分析仪测定结果呈正相关(r2=0.996),回归方程为Y=0.953 X+0.519;D-10全自动糖化血红蛋白分析仪和7170A全自动生化分析仪测定结果呈正相关(r2=0.996),回归方程为Y=0.925 X+0.576;HA-8160全自动糖化血红蛋白分析仪和7170A全自动生化分析仪测定结果呈正相关(r2=0.998),回归方程为Y=0.969 X+0.081。结论在保证实验室质量控制的前提下,均可以采用以上3种不同的仪器检测糖化血红蛋白。

关键词：糖化血红蛋白离子交换色谱法亲和色谱法

增强型血流成像技术检测胎儿肺静脉优越性的分析

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疑难病杂志 2015年第5期14卷 504-507页

作者：景艳郑艳芬王铁英魏宏英宁玮杨霞辛强内蒙古包头市第四医院超声医学科 014030 包头医学院医学技术学院

目的探讨增强型血流成像技术(E-flow)检测胎儿肺静脉方面的优势,评价产前检测胎儿肺静脉在筛选和协助早期诊断胎儿先天性心脏病中的临床应用价值。方法选择190例正常胎儿(正常胎儿组)和产前诊断为心脏发育异常的胎儿6例(先天性心脏病组)... 详细信息

目的探讨增强型血流成像技术(E-flow)检测胎儿肺静脉方面的优势,评价产前检测胎儿肺静脉在筛选和协助早期诊断胎儿先天性心脏病中的临床应用价值。方法选择190例正常胎儿(正常胎儿组)和产前诊断为心脏发育异常的胎儿6例(先天性心脏病组),比较应用E-flow和多普勒彩色超声血流成像(CDFI)2种技术对胎儿肺静脉的显示情况,并测量及评价相关肺静脉血流参数。结果 16~24周胎儿肺静脉的显示率E-flow技术明显高于CDFI(χ~2=14.769,P0.05)。肺静脉的内径随孕周增长而增宽,S峰、D峰及A波随孕周增长而增快;PI、PVI随孕周增长而逐渐降低。胎儿肺静脉内径及S、D、A与胎龄呈明显的正相关(r=0.973、0.959、0.944、0.950,P<0.05);PI、PVI与胎龄呈负相关(r=-0.821、-0.855,P<0.05)。先天性心脏病组肺静脉PI及PVI较胎龄相匹配的正常胎儿组较高,A波较低,2组比较差异有统计学意义(P<0.05)。结论应用E-Flow技术产前检查胎儿肺静脉,可更早更清晰地显示胎儿肺静脉的走行情况,对临床尽早诊断胎儿先天性心脏病提供有价值的信息。

关键词：增强型血流成像超声心动图胎儿先天性心脏病肺静脉

Rupture segmentation and slip partitioning of the mid-eastern part of the Kunlun Fault,north Tibetan Plateau

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Science China Earth Sciences 2011年第11期54卷 1730-1745页

作者： LI ChenXia XU XiWei WEN XueZe zheng RongZhang CHEN GuiHua YANG Hu AN yanfen GAO Xiang Institute of Geology China Earthquake Administration National Center of Active Fault Studies Beijing 100029 China Lanzhou Seismological Institute of China Earthquake Administration Lanzhou 730000 China Earthquake Administration of Sichuan Province Chengdu 610041 China

The Kunlun Fault, an active fault on the border between the Bayan Har and Kunlun-Qaidam blocks, is one of the major left lateral strike-slip faults in the Tibetan Plateau. Previous research has not reached a consensus on agreeable slip rates along much of its length and the slip rate gradient along the eastern part, both of which play critical roles in a range of models for the eastward extrusion and thickened crust of the Tibetan Plateau. New slip rates have been determined at sites along the eastern part of the Kunlun Fault by dating deposits and measuring atop displaced fluvial terrace risers. Field investigations and interpretation of satellite images reveal geometrical features of the fault and the late Quaternary offset, new earthquake ruptures and surface-rupturing segmentation, from which long-term slip rates and earthquake recurrence intervals on the fault are estimated. The tectonic geomorphology method has determined that the long-term horizontal slip rates on the Tuosuohu, Maqin and Ma- qu segments from west to east are 11.2±1, 9.3±2, and 4.9±1.3 mm/a while their vertical slip rates are 1.2±0.2, 0.7±0.1, and 0.3 mm/a in the late Quaternary. Results indicate that the slip rates regularly decrease along the eastern -300 km of the fault from 〉10 to 〈5 mm/a. This is consistent with the decrease in the gradient such that at the slip rate break point is at the triple point intersection with the transverse fault, which in turn is transformed to the Awancang Fault. The vector decomposition for this tectonic transformation shows that the western and eastern branches of the Awancang Fault fit the slip-partitioning mode. The slip rate of the southwestern wall is 4.6 mm/a relative to the northeastern wall and the slip direction is 112.1°. The mid-eastern part of the Kunlun Fault can be divided into three independent segments by the A＇nyemaqen double restraining bend and the Xigongzhou intersection zone, which compose the surface rupture segmentation indicators for t

关键词： mid-eastern Kunlun Fault slip rate surface rupture segmentation slip partition paleoearthquake Tibetan Plateau

三维成像及H-Flow技术结合彩色多普勒超声评价胎儿宫内缺氧状况的研究

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医学影像学杂志 2018年第2期28卷 303-307页

作者：夏春华曾华北郑艳芬任海波李一凡江苏省宿迁市妇产医院江苏宿迁223800 包头医学院第二附属医院内蒙古包头041010

目的探讨三维成像及H-Flow技术结合彩色多普勒超声在评价胎儿宫内缺氧状况中的临床价值及三维血管重建技术在发现胎儿宫内缺氧原因中的优势。方法在产科常规检查项目的基础上,经彩色多普勒检测胎心、脐动脉和大脑中动脉等血流参数,指标... 详细信息

目的探讨三维成像及H-Flow技术结合彩色多普勒超声在评价胎儿宫内缺氧状况中的临床价值及三维血管重建技术在发现胎儿宫内缺氧原因中的优势。方法在产科常规检查项目的基础上,经彩色多普勒检测胎心、脐动脉和大脑中动脉等血流参数,指标异常者通过三维成像及H-Flow技术,观察脐带形态、走行及空间转向,寻找缺氧的原因。同时利用实时三维成像观察胎儿活动状态及颜面表情。结果彩色多普勒血流参数是诊断胎儿宫内缺氧的基本指标,脐带、羊水和胎盘因素是造成缺氧的主要原因,三维成像及H-Flow技术适用于寻找宫内缺氧的原因,超声诊断与产后符合率为100%。结论三维成像及H-Flow技术结合彩色多普勒超声可以及时准确的诊断胎儿宫内窘迫的原因和程度,是对二维超声及彩色多普勒的有效补充,为临床诊疗和选择恰当的生产方式提供重要参考依据。

关键词：三维成像及H—Flow技术彩色多普勒胎儿缺氧

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高原脱适应人群外周血淋巴细胞亚群的变化

昆明医科大学学报 2023年第10期44卷 122-128页

作者：张立群柴敏东潘志强郑艳芬赵坤赵鑫张琳张宁平中国人民解放军32261部队疗养科云南安宁650307

目的了解移居高原低氧环境人群返回中海拔地区后外周血淋巴细胞亚群的变化,探讨高原脱适应对健康人免疫功能的影响。方法采用流式细胞术检测47例高原人员返回中海拔地区15 d内淋巴细胞亚群的变化。结果高原居住时间≥1 a的人员在返回中... 详细信息

目的了解移居高原低氧环境人群返回中海拔地区后外周血淋巴细胞亚群的变化,探讨高原脱适应对健康人免疫功能的影响。方法采用流式细胞术检测47例高原人员返回中海拔地区15 d内淋巴细胞亚群的变化。结果高原居住时间≥1 a的人员在返回中海拔地区第1天比高原居住时间0.05)。结论高原脱适应人群外周血淋巴细胞亚群与年龄、海拔及高原居住时间的分析提示高原居住时长会影响机体脱适应期的细胞免疫和体液免疫。高原脱适应期人外周血CD8+T淋巴细胞、NK细胞及CIK细胞百分含量上升,提示高原脱适应主要通过作用细胞免疫和非特异性免疫过程影响机体免疫功能。

关键词：高原脱适应 T淋巴细胞 B淋巴细胞自然杀伤细胞细胞因子诱导的杀伤细胞

Atmospheric levels and distribution of Dechlorane Plus in an E-waste dismantling region of East China

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Science China Chemistry 2017年第2期60卷 305-310页

作者： Huizhong Sun Yingming Li Pu Wang Shucheng zheng Julius Matsiko Dou Wang Weiwei Zhang yanfen Hao Qinghua Zhang Guibin Jiang State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085 China University of Chinese Academy of Sciences Beijing 100049 China

Atmospheric concentrations of Dechlorane Plus(DP)were investigated in Taizhou,an electronic-waste(E-waste)dismantling region in East *** air samplers with polyurethane foam(PUF)disks were deployed every three months during the sampling period of September 2009-August *** total DP(syn-and anti-DP)concentrations in air ranged from not detected to 277 pg/m^3,with a mean concentration of 53.9 pg/m^3.A generally declining trend of DP levels was found from the E-waste dismantling region to the peripheral *** median values of total DP concentrations in autumn,winter,spring and summer were 52.2,28.8,39.7 and 30.1 pg/m^3,*** seasonal variations of DP concentrations were mainly associated with the intensity of E-waste dismantling activities and meteorological *** mean value of anti-DP fractional abundance(f_(anti))was 0.74±0.08,which was consistent with those in the commercial DP *** study confirmed a significant emission source related to the distribution of atmospheric DP in the E-waste dismantling area and supplied information for the seasonal variation of DP in the atmosphere.

关键词： Dechlorane Plus air E-waste dismantling seasonal variation

Determination of PCDD/Fs and dioxin-like PCBs in food and feed using gas chromatography-triple quadrupole mass spectrometry

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Science China Chemistry 2017年第5期60卷 670-677页

作者： Huizhong Sun Pu Wang Honghua Li Yingming Li Shucheng zheng Julius Matsiko yanfen Hao Weiwei Zhang Dou Wang Qinghua Zhang State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Beijing 100085 China University of Chinese Academy of Sciences Beijing 100049 China Institute of Environment and Health Jianghan University Wuhan 430056 China

A method was developed on a gas chromatograph coupled to a triple quadrupole mass spectrometer(GC-MS/MS) for trace level determination of polychlorinated dibenzo-p-dioxins/dibenzofurans(PCDD/Fs) and dioxin-like polychlorinated biphenyls(DL-PCBs) in food and feed. The results demonstrated good sensitivity and repeatability for PCDD/Fs and DL-PCBs at an extremely low level(10 pg mL^(-1) for 2,3,7,8-TCDD/F), as well as wide linear response of over 3 or 4 orders of magnitude in concentration ranges; 0.5–200 ng mL^(-1) for PeCDD/F and 0.2–2000 ng mL^(-1) for DL-PCBs. The method detection limits for PCDD/Fs and DL-PCBs were in the range from 0.018–0.17 pg g^(-1) to 0.13–0.36 pg g^(-1), respectively. The performance of the GC-MS/MS for food and feed sample analysis showed high precision and accuracy compared to the high resolution gas chromatograph/high resolution mass spectrometer. The results indicated the feasibility of GC-MS/MS as a confirmatory method for the measurement of PCDD/Fs and DL-PCBs in food and feed as required by European Union legislation.

关键词： PCDD/Fs DL-PCBs food feed GC-MS/MS

三维血管重建技术结合彩色多普勒超声评价胎儿宫内缺氧的价值

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江苏医药 2017年第7期43卷 498-500,F0003页

作者：夏春华曾华北郑艳芬任海波李春梅蔡春梅杨秀娟宿迁市妇产医院超声科江苏省223800 宿迁市妇产医院麻醉科江苏省223800 包头医学院第二附属医院超声科

目的探讨三维血管重建技术结合彩色多普勒超声评价胎儿宫内缺氧的价值。方法孕妇61例,孕14~43周。二维彩色多普勒超声检测胎心、脐动脉和胎儿大脑中动脉等血流参数异常,提示胎儿宫内缺氧;通过三维血管重建技术,观察脐带形态、走行及空... 详细信息

目的探讨三维血管重建技术结合彩色多普勒超声评价胎儿宫内缺氧的价值。方法孕妇61例,孕14~43周。二维彩色多普勒超声检测胎心、脐动脉和胎儿大脑中动脉等血流参数异常,提示胎儿宫内缺氧;通过三维血管重建技术,观察脐带形态、走行及空间转向,同时利用实时三维成像观察胎儿活动状态及颜面表情。结果二维超声诊断胎盘和脐带异常的临床符合率为96.9%和89.3%,二维超声+三维/煊流技术检查诊断胎盘和脐带异常的临床符合率均为100%,二维超声+三维/煊流技术超声诊断的临床总符合率高于单纯二维超声(100%vs.93.1%)(P<0.05)。结论彩色多普勒超声结合三维血管重建技术能准确诊断胎儿宫内窘迫的原因和程度,为临床选择恰当的分娩方式提供重要参考依据。

关键词：胎儿宫内窘迫三维血管重建技术彩色多普勒超声

Simultaneous acquisition of Fe3O4 monocrystals:Tunable magnetic properties with various morphologies

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Progress in Natural Science:Materials International 2020年第1期30卷 41-46页

作者： Zemin zheng Yiming Cao Zhe Li Huiyong Li Dafeng Hu Hao Jiang Xuemin Geng Jiangwei Lu Xudong Zhang Peng Yang yanfen Wan School of Materials Science and Engineering Yunnan Key Laboratory for Micro/nano Materials & TechnologyYunnan University Center for Magnetic Materials and Devices & Key Laboratory for Advanced Functional and Low Dimensional Materials of Yunnan Higher Education Institute Qujing Normal University

Fe3O4nanoparticles（NPs） with a face-centered cubic（fcc） structure and two different morphologies（nanospheres and nanoprisms） were synthesized by a facile one-step *** synthesized Fe3O4nanospheres and nanoprisms were monocrystalline and separable in a magnetic *** different volume ratios of oleylamine（OAm） to dibenzyl ether,the sizes of the prepared Fe3O4NPs ranged from 5 to 21 *** OAm amount in the synthesis can significantly control the morphology of *** the OAm content increased from 10 ml to 30 ml,the faceted nanoprisms shrank while the nanospheres *** an OAm content of 25 ml,the nanoprisms diminished while more hexagonal and sphere-like particles appeared,implying a critical point of morphology transition from triangle to *** magnetic properties also depended on the NP morphology and *** prepared Fe3O4NPs are promising candidates in medical applications such as magnetic resonance imaging,targeted drug delivery,blood purification,and tumor hyperthermia.

关键词： Fe3O4 Nanoparticles Nanoprism Nanosphere Superparamagnetic