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Potential therapeutic effects and applications of Eucommiae Folium in secondary hypertension

Journal of Pharmaceutical Analysis 2022年第5期12卷 711-718页

作者： Mengyuan Li yanchao zheng Sha Deng Tian Yu Yucong Ma Jiaming Ge Jiarong Li Xiankuan Li Lin Ma College of Chinese Materia Medica Tianjin University of Traditional Chinese MedicineTianjin301617China Pharmaceutical Research Development Center Tianjin Yibeiyuan Natural Products Technology Co.Ltd.Tianjin300457China College of Traditional Chinese Medicine Changchun University of Chinese MedicineChangchun130117China

Eucommiae Folium(EF),a traditional Chinese medicine,has been used to treat secondary hypertension,including renal hypertension and salt-sensitive hypertension,as well as hypertension caused by thoracic aortic endothelial dysfunction,a high-fat diet,and oxidized low-density *** antihypertensive components of EF are divided into four categories:flavonoids,iridoids,lignans,and phenylpropanoids,such as chlorogenic acid,geniposide acid and pinoresinol *** regulates the occurrence and development of hypertension by regulating biological processes,such as inhibiting inflammation,regulating the nitric oxide synthase pathway,reducing oxidative stress levels,regulating endothelial vasoactive factors,and lowering blood ***,its molecular antihypertensive mechanisms are still unclear and require further *** this review,by consulting the relevant literature on the antihypertensive effects of EF and using network pharmacology,we summarized the active ingredients and pharmacological mechanisms of EF in the treatment of hypertension to clarify how EF is associated with secondary hypertension,the related components,and underlying *** results of the network pharmacology analysis indicated that EF treats hypertension through a multicomponent,multi-target and multi-pathway *** particular,we discussed the role of EF targets in the treatment of hypertension,including epithelial sodium channel,heat shock protein70,rhoassociated protein kinase 1,catalase,and superoxide *** relevant signal transduction pathways,the ras homolog family member A(RhoA)/Rho-associated protein kinase(ROCK)and nicotinamide adenine dinucleotide phosphate(NADPH)oxidase/eNOS/NO/Ca^(2+)pathways,are also discussed.

关键词： Eucommiae folium Secondary hypertension Ingredient Target Pathway

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基于数据挖掘的竞争情报与知识管理融合模型研究

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图书馆学研究 2010年第9期 28-31页

作者：郑艳超华南师范大学经济与管理学院

文章在论述数据挖掘与竞争情报、知识管理的关系基础上,设计出基于数据挖掘的竞争情报与知识管理融合模型。该融合模型由以竞争情报工作人员为核心的竞争情报工作循环、以数据挖掘为中心的DM循环、以企业内部员工为中心的人类知识开发... 详细信息

文章在论述数据挖掘与竞争情报、知识管理的关系基础上,设计出基于数据挖掘的竞争情报与知识管理融合模型。该融合模型由以竞争情报工作人员为核心的竞争情报工作循环、以数据挖掘为中心的DM循环、以企业内部员工为中心的人类知识开发循环三部分组成。并用广东电信研究院竞争情报与知识管理的业务流程案例来阐述该模型的应用,突出该融合模型的实用性。

关键词：数据挖掘竞争情报知识管理

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Fluorinated poly(p-triphenylene isatin)anion exchange membranes based on hydrophilic hydroxyl side chain modulation for fuel cells

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Journal of Energy Chemistry 2025年第1期100卷 702-709页

作者： Yiman Gu yanchao Zhang Zhanyu Li Yijia Lei Baozeng Sun Xiaoyu Yu Zhe Wang College of Chemistry and Life Science Changchun University of TechnologyChangchun 130012JilinChina College of Chemical Engineering Changchun University of TechnologyChangchun 130012JilinChina School of Materials Science and Engineering Changchun University of TechnologyChangchun 130012JilinChina Key Laboratory of Advanced Functional Polymer Membrane Materials of Jilin Province Changchun 130012JilinChina

The development of alkaline fuel cells is moving forward at an accelerated pace,and the application of ether-free bonded polymers to anion exchange membranes(AEMs)has been widely ***,the question of the“trade-off”between AEM ionic conductivity and dimensional stability remains *** strategy of inducing microphase separation to improve the performance of AEM has attracted much attention recently,but the design of optimal molecular structures is still being ***,this work introduced different ratios of 3-bromo-1,1,1-trifluoroacetone(x=40,50,and 60)into the main chain of poly(p-terphenylene isatin).Because fluorinated groups have excellent hydrophobicity,hydrophilic hydroxyl-containing side chains are introduced to jointly adjust the formation of phase separation *** results show that PTI-PTF_(50)-NOH AEM with the appropriate fluorinated group ratio has the best ionic conductivity and alkali stability under the combined effect of *** has an ionic conductivity of 133.83 mS cm^(-1)at 80°*** addition,the OH-conductivity remains at 89%of the initial value at 80°C and 3 M KOH for 1056 h of *** cell polarization curve based on PTI-PTF_(50)-NOH shows a power density of 734.76 mW cm^(-2)at a current density of 1807.7 mA cm^(-2).

关键词： Anion exchange membranes Poly(p-terphenylene isatin) Hydrophilic-hydrophobic phase separation Fluorinated group

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Microdynamic modulation through Pt–O–Ni proton and electron “superhighway” for pH-universal hydrogen evolution

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Journal of Energy Chemistry 2025年第2期101卷 808-815页

作者： Dewen Wang Yuting Chen Bohan Yao Tian Meng yanchao Xu Dongxu Jiao Zhicai Xing Xiurong Yang State Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences University of Science and Technology of China Department of Chemistry Shenzhen Grubbs Institute and Guangdong Provincial Key Laboratory of Energy Materials for Electric Power Southern University of Science and Technology State Key Laboratory of Automotive Simulation and Control School of Materials Science and Engineering Jilin University

Optimizing the microdynamics in alkaline and neutral conditions is a significant but challenging task in developing pH-universal hydrogen evolution（HER） ***,a unique Pt-O-Ni bridge has been constructed to alter the coordination and electronic environment between Pt nanoparticles（Pt_n）and nickel metaphosphate（NPO） substrate（Pt-NPO）.Sufficient electron transfer from NPO to Pt_n to maintain an electron-rich environment and a low valence state of Pt_***,H*is produced from the H2O dissociation on Ni site and then spillover toward Pt sites to bind into H2,which makes up for the insufficient H2O dissociation ability of Pt in Volmer ***-NPO exhibits long-term stability and only need the overpotentials of 22.3,33.0 and 30.5 mV to attain 10 mA cm-2in alkaline,neutral and acidic media,*** anion-exchange membrane（AEM） water electrolyzer catalyzed by Pt-NPO shows high water electrolysis performance that a cell voltage of 1.73 V is needed to obtain the current density of500 mA cm-2in 1 M KOH at 80℃,at the same time maintains good stability for 350 *** regulation strategy proposed in this work is helpful for the design and synthesis of highly efficient pH-universal HER electrocatalysts.

关键词： Atomic and electronic regulation Hydrogen evolution reactions Metal-support interactions Microdynamics pH-universal HER electrocatalysts

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Mutagenesis in Zebrafish by Transposon Gene Trap System

Mutagenesis in Zebrafish by Transposon Gene Trap System

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2010·第一届斑马鱼学术研讨会

作者： Shuyan Yang,yanchao Han,Xiaofeng zheng,Jingyuan Tong,Cong Xiong,Anming Meng School of Life Sciences,Tsinghua University,Beijing 100084,China

Zebrafish is a powerful model organism for studying vertebrate genetics and *** identify genes involved in development and diseases,the strategies of chemical and insertional genetic screens have been carried out. Man...

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Wetland and habitat dynamics in the evolving landscape of the Middle Yangtze River Basin

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Journal of Geographical Sciences 2025年第1期35卷 88-111页

作者： YANG Peng SUN Kaiya ZHU yanchao XIA Jun HUANG Heqing SONG Jingxia SHI Xiaorui LU Xixi Hubei Key Laboratory of Regional Ecology and Environmental Change School of Geography and Information EngineeringChina University of GeosciencesWuhan430074China State Key Laboratory of Water Resources and Hydropower Engineering Science Wuhan UniversityWuhan430072China Department of Geography National University of Singapore10 Kent RidgeCrescent119260Singapore

Wetlands play a critical role in the global *** Middle Yangtze River Basin(MYRB),known for its abundant wetland resources,has experienced notable changes resulting from the complex interplay of environmental ***,we investigated the spatiotemporal characteristics of wetland ecological quality in the MYRB from 2001 to *** the random forest(RF)regression algorithm and patch-generated land-use simulation(PLUS)model,we forecasted variations in wetland habitat quality and their determinants under the Shared Socioeconomic Pathway-Representative Concentration Pathway(SSPRCP)framework from 2035 to *** main findings are as follows:(1)The RF algorithm was optimal for land-use and land-cover(LULC)classification in the MYRB from 2001 to 2020,when notable changes were observed in water bodies and ***,the forested area exhibited an increase and decrease of 3.9%and 1.2%under the SSP1-2.6 and SSP5-8.5 scenarios,respectively,whereas farmland exhibited a diminishing trend.(2)Wetlands were primarily concentrated in the central and eastern MYRB,with counties in the southwest exhibiting superior ecological-environmental quality from 2001 to ***,wetland coverage revealed significantly high level,significant changes,frequent but relatively minor changes under the SSP1-2.6,SSP2-4.5,and SSP 5-8.5 scenarios,respectively.(3)Regions with lower habitat quality were primarily concentrated in urbanized areas characterized by frequent human activities,indicating a clear degradation in habitat quality across different *** conclusion,we established a foundational framework for future investigations into the eco-hydrological processes and ecosystem quality of watersheds.

关键词： Middle Yangtze River Basin wetland environmental change habitat quality multiple scenarios

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卫矛属植物资源及其园林应用前景

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绿色科技 2019年第19期21卷 54-58页

作者：郑彦超吴昊国家林业和草原局华东调查规划设计院

指出了我国卫矛属植物资源丰富,分布广泛,植株、枝、叶、花、果实形态多样,色泽美丽,在园林应用上拥有巨大潜力,目前应用较多的卫矛属植物有9种,在此推荐19种具有园林应用前景的卫矛属植物。以供参考。

关键词：卫矛属植物资源园林应用前景

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A New Antiarch,Bothriolepis zhujiangyuanensis ***.,from the Eifelian(Middle Devonian)of Qujing,Yunnan,SW China

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Acta Geologica Sinica(English Edition) 2025年第1期99卷 1-14页

作者： XIAN Zumin PAN Zhaohui WANG Jianhua JIA Liantao ZHAO Yingtian LUO yanchao ZHU Min Yunnan Key Laboratory for Palaeobiology Institute of PalaeontologyYunnan UniversityKunming 650500China Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences Institute of Vertebrate Paleontology and PaleoanthropologyChinese Academy of SciencesBeijing 100044China University of Chinese Academy of Sciences Beijing 100044China Qujing Normal University Yunnan 655000China

A new species of Bothriolepis(Placodermi,Antiarcha),*** ***.,is described from the Eifelian(Middle Devonian)Shangshuanghe Formation at the Pearl River Source Scenic Area,Qujing,Yunnan Province,southwestern China and is characterized by a broad postpineal plate bearing a straight anterior margin,a premedian plate wider than long,and a weakly developed dorsal median ridge of the trunk *** the eighth Bothriolepis taxon in China,*** *** a wealth of morphological data to clarify the intrageneric *** parsimony analysis,using a revised data set of the genus with 76 ingroup taxa and 72 characters,yields a well-resolved consensus tree for *** phylogenetic result shows a sister-group relationship between *** and *** from Kazakhstan,corroborating the biogeographic proximity between the South China and Kazakhstania blocks during the Middle Devonian.

关键词： vertebrate paleontology placoderms Bothriolepis phylogeny paleobiogeography Eifelian Yunnan Province

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浙江庆元巾子峰国家森林公园植被群落的数量分类与排序

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浙江农林大学学报 2021年第3期38卷 523-533页

作者：李伟成郑彦超盛海燕楼毅于辉国家林业和草原局竹子研究开发中心浙江省竹子高效加工重点实验室浙江杭州310012 国家林业和草原局华东调查规划设计院浙江杭州310019 杭州市生态环境科学研究院浙江杭州310014 大兴安岭林业集团公司黑龙江大兴安岭165000

【目的】了解浙江省庆元县巾子峰国家森林公园中植被群落与环境因子之间的关系。【方法】采用样方调查法调查庆元巾子峰国家森林公园中48个样方的植被群落,并进行数量分类和排序,分析群落类型、分布特征及其与环境因子的相关关系。【结... 详细信息

【目的】了解浙江省庆元县巾子峰国家森林公园中植被群落与环境因子之间的关系。【方法】采用样方调查法调查庆元巾子峰国家森林公园中48个样方的植被群落,并进行数量分类和排序,分析群落类型、分布特征及其与环境因子的相关关系。【结果】(1)共调查记录植物66科129属193种。植物物种数较多的科分别为壳斗科Fagaceae(19种)、樟科Lauraceae(18种)、山茶科Theaceae(9种)、杜鹃花科Ericaceae(9种)、蔷薇科Rosaceae(9种)、冬青科Aquifoliaceae(6种)、禾本科Gramineae(6种)、茜草科Rubiaceae(6种)、金粟兰科Chloranthaceae(5种)和百合科Liliaceae(5种)。乔木层优势物种主要为杉木Cunninghamia lanceolata、木荷Schima superba、黄山松Pinus taiwanensis、青冈Cyclobalanopsis glauca、甜槠Castanopsis eyrei、红楠Machilus thunbergii、少叶黄杞Engelhardia fenzelii和拟赤杨Alniphyllum fortunei。灌木层优势种为杜茎山Maesa japonica、草珊瑚Sarcandra glabra、隔药柃Eurya muricata和映山红Rhododendron simsii。草本层优势种为蕨Pteridum aquilinum var. latiusculum、芒萁Dicranopteris dichotoma、黑足鳞毛蕨Dryopteris fuscipes、中华薹草Carex chinensis、白茅Imperata cylindrica、江南卷柏Selaginella moellendorffii和荩草Arthraxon hispidus。(2)双向指示种分析将植被群落分成10个群丛类型。(3)10个群丛在去趋势对应分析排序图中呈现有规律的分布,反映了较好的环境梯度。(4)典范对应分析排序结果表明:影响各群丛分布的最重要环境因子是海拔,其次为土壤类型、土壤温度和坡度;各优势树种的分布特征与各群丛的分布特征具有较好的相似性。【结论】海拔是影响庆元巾子峰国家森林公园植被群落分布的最重要环境因子,海拔对山地植被群落分布具有决定性作用。

关键词：森林生态学巾子峰国家森林公园植被群落数量分类排序环境因子

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从空间尺度论述陆生野生动物生境选择研究进展

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绿色科技 2015年第2期17卷 5-8,13页

作者：郑彦超吴昊刘善辉国家林业局华东林业调查规划设计院浙江杭州310019 北京林业大学自然保护区学院北京100083

指出了生境是动物生存和繁衍的重要场所,生境的质量及其可利用程度是决定动物种群生死存亡的关键因素。因此,研究动物的生境利用特点成为生物保护学研究的热点。综述了不同空间尺度上陆生野生动物生境选择研究的概况,以期对今后开展生... 详细信息

指出了生境是动物生存和繁衍的重要场所,生境的质量及其可利用程度是决定动物种群生死存亡的关键因素。因此,研究动物的生境利用特点成为生物保护学研究的热点。综述了不同空间尺度上陆生野生动物生境选择研究的概况,以期对今后开展生境利用研究工作时在方法的选取方面提供借鉴和指导。

关键词：生境选择微生境宏生境家域空间尺度

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