检索结果-南通市图书馆

海上风电海缆风机端弯曲保护装置及安装技术研究

在线全文

学校读者我要写书评

暂无评论

机电工程技术 2024年第9期53卷 12-16,46页

作者：林峰李斯魏薛驰胡明汤洋石彦彪王中权张永明张永康江苏中天科技股份有限公司江苏南通226400 广东工业大学机电工程学院广东省海洋能源装备先进制造技术重点实验室广州510006 国家电投集团广东电力有限公司广州510700 南方海上风电联合开发有限公司广东珠海519020 宁波东方电缆股份有限公司浙江宁波315000

由于海缆弯曲刚度较小,在风机单桩基础附近的这段海缆在位运行过程中受到洋流、涌浪、潮汐等动态载荷作用下,海缆容易发生弯曲破坏,因此需要对海缆采取弯曲保护措施。提出一种夹具倒刺型海缆弯曲保护装置,并详细介绍了该夹具倒刺型海缆... 详细信息

由于海缆弯曲刚度较小,在风机单桩基础附近的这段海缆在位运行过程中受到洋流、涌浪、潮汐等动态载荷作用下,海缆容易发生弯曲破坏,因此需要对海缆采取弯曲保护措施。提出一种夹具倒刺型海缆弯曲保护装置,并详细介绍了该夹具倒刺型海缆弯曲保护装置的工作原理以及接入风机基础的安装流程和注意事项。相对于传统的海缆弯曲保护方式而言,该装置不需要J形管及配套的金属套笼,采用的多层交错自回弹的倒刺卡齿结构,可以将海缆定位限制在风机塔筒壁的电缆开孔处,尾部的弯曲限制器保证了对悬空段海缆的弯曲保护,有效保证了海缆安全的同时又降低了工程造价。研究成果能够为我国海上风电场建设中的海缆弯曲保护提供技术参考。

关键词：海上风电海缆弯曲保护装置与安装

Induction of the apoptosis, degranulation and IL-13 production of human basophils by butyrate and propionate via suppression of histone deacetylation

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Induction of the apoptosis, degranulation and IL-13 producti...

Regulation of T lymphocyte development and homeostasis by Aurora-A

第十四届全国免疫学学术大会

作者： yanbiao shi Meizhen Xu Shuai Pan Hui Wang Jiangsu Key Laboratory of Immunity and Metabolism Department of Pathogenic Biology and ImmunologyXuzhou Medical University

Background: Allergic diseases are orchestrated by dysregulated Th2-type immune responses involving multiple immune effector cells. Basophils are one of the key effector cells in mediating allergic immune responses through releasing cytokines and mediators e.g. IL-4, IL-13 and histamine. Short chain fatty acids(SCFAs) produced by commensal intestinal microbiota via fermentation of indigestible dietary fibers are reported to suppress allergic immune reactions by targeting mast cells, eosinophils and type 2 innate lymphoid cells(ILC2). However, the role of SCFAs on basophils are not known yet. In this study, we aimed to elucidate the function of SCFAs on human ***: Human basophils were purified from healthy donors by FACS sorting. The expression of surface receptors and the apoptosis were analyzed by flow cytometric analysis. The cytokines IL-4 and IL-13 and histamine release were measured by ***: Human basophils express SCFAs receptor GPR41, which was enhanced by IL-3 rather than other established modulators e.g. anti-IgE, fMLP or C5a. Acetate but not propionate and butyrate induced calcium influx via GPR41. However, SCFA propionate and butyrate rather than acetate induced the apoptosis of basophils. In vitro cytokine release assay showed that propionate and butyrate suppressed the expression of IL-4 while acetate, propionate and butyrate enhanced the expression of IL-13. Moreover, propionate and butyrate enhanced the histamine release associated with increased expression of the basophil degranulation marker ***: Our findings demonstrate that a complicated role of SCFAs in mediating the biology of basophils. The effects of SCFAs in regulating basophils-associated allergic disorders need to be further justified.

关键词： basophil Short chain fatty acids histone deacetylation

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Regulation of T lymphocyte development and homeostasis by Au...

BHLHE41 ameliorates the pathology of animal models of multiple sclerosis by promoting microglial phagocytosis

第十四届全国免疫学学术大会

作者： Sijia Gao Shuai Pan yanbiao shi Meizhen Xu RuiXue Bai Jinfeng Ren Hui Wang Xuzhou Medical University

The serine/threonine kinase Aurora-A plays a crucial role in controlling cellular division and has been implicated to contribute to *** cancer clinical trials have reported suppression of peripheral lymphocyte counts by treatment with Aurora-A inhibitor,indicating a possible role of Aurora-A in regulating lymphocytes *** lab has recently reported that ablation of Aurka inhibits the development and homeostasis of B *** it has been shown that Aurora-A regulates T lymphocyte activation by controlling LCK phosphorylation,its role in regulating the biology ofT lymphocytes remains to be further ***,we in the present study generated T cell specific Aurka knockout mice,namely LckAurka mice and CD4Aurka mice,which had Aurka deleted at the stage of double negative(DN) 3 and double positive(DP),*** of Aurka in LckAurka mice led to a significant reduction of DN3 and DN4 thymocytes in the thymus while no change of thymocyte development in CD4Aurka *** analysis revealed reduced CD4and CD8T lymphocytes in secondary lymphoid organs from both LckAurka and CD4Aurka ***,this reduction was associated with loss of naive CD4and CD8T *** addition,increased apoptosis of DN thymocytes and naive CD4T cells from LckAurka mice was observed upon in vitro stimulation with *** results indicate that Aurora-A might regulate T cell development at the DN stages and T cell homeostasis through acting downstream of IL-7 signaling pathway.

关键词： Aurora-A lymphocyte development peripheral homeostasis

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

BHLHE41 ameliorates the pathology of animal models of multip...

第十四届全国免疫学学术大会

作者： Hui Li Li Hong MeiZhen Xu RuiXue Bai yanbiao shi SiJia Gao JinFeng Ren Cheng He KuiYang Zheng Hui Wang Xuzhou Medical University

Background:Microglia are specialized macrophages in central nervous system(CNS) that play crucial roles in CNS homeostasis and neuronal degenerative disorders *** sclerosis(MS),which is characterized by demyelination in *** of myelin debris by microglia promotes remyelination and MS ***,the molecular mechanisms controlling the function of microglia in MS remain to be *** factor BHLHE41 is preferentially expressed in microglia and alveolar macrophages among immune cells and contributes to the self-renewal of alveolar *** this study,we aimed to examine the function of BHLHE41 in regulating the biology of microglia and the pathogenesis of ***:Bhlhe41 reporter and knockout mice Bhlhe41 were generated by insertion of a tdTomato-2 A-Cre-poIyA cassette to the locus of Bhlhe41 using CRISPR-Cas9 ***41 mice and Bhlhe41 Rosa26mice were used to examine the expression of BHLHE41 in CNS by flow cytometric analysis and *** phagocytosis was assayed by in vivo and in vitro studies using pH rodo Green *** and Zymosan A,*** autoimmune encephalomyelitis(EAE) and cuprizone-induced MS models were performed to examine the role of BHLHE41 in the pathogenesis of ***:BHLHE41 was preferentially and highly expressed in microglia but not CNS-associated macrophages,neurons,astrocytes and oligodendrocytes in *** of Bhlhe41 suppressed microglial phagocytosis,delayed the recovery of EAE mice at the recovery ***,Bhlhe41 deficiency led to reduced proliferation and activation of microglia and defected clearance of myelin debris in the area of demyelination in CPZ-induced MS ***:Microglial-biased transcription factor BHLHE41 may ameliorate the pathology of MS via promoting microglial phagocytosis of myelin debris.

关键词： Microglia Multiple Sclerosis Phagocytosis BHLHE41

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

卤氧化铋光催化去除环境污染物

华中师范大学学报(自然科学版) 2021年第6期55卷 925-940+975页

作者：全凤娇石彦彪孙红卫申文娟李建芬贾法龙张礼知武汉轻工大学化学与环境工程学院华中师范大学环境与应用化学研究所/农药与化学生物学教育部重点实验室上海交通大学环境科学与工程学院

卤氧化铋基半导体材料具有铋氧层和卤素层交替排布的独特层状结构和易调节的禁带宽度,在直接利用太阳光去除环境污染物方面表现出优异性能和巨大潜力.基于国内外相关研究进展及本课题组近年来的研究成果,该文综述了卤氧化铋材料(氯氧化... 详细信息

卤氧化铋基半导体材料具有铋氧层和卤素层交替排布的独特层状结构和易调节的禁带宽度,在直接利用太阳光去除环境污染物方面表现出优异性能和巨大潜力.基于国内外相关研究进展及本课题组近年来的研究成果,该文综述了卤氧化铋材料(氯氧化铋、溴氧化铋和碘氧化铋)光催化去除环境污染物方面的研究成果,主要包括卤氧化铋光催化材料的设计和改性策略,以及上述新材料在重金属离子去除、有机污染物降解和空气净化等领域的研究进展.最后,提出了卤氧化铋光催化材料在环境污染控制领域的研究展望.

关键词：光催化卤氧化铋改性有机污染物空气净化

Biodegradable metals for bone defect repair:A systematic review and meta-analysis based on animal studies

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Bioactive Materials 2021年第11期6卷 4027-4052页

作者： Jiazhen Zhang yanbiao Jiang Zhizhong Shang Bing Zhao Mingyue Jiao Wenbo Liu Maobo Cheng Bao Zhai Yajuan Guo Bin Liu Xinli shi Bin Ma Center for Medical Device Evaluation National Medical Products AdministrationBeijing100081PR China Evidence-Based Medicine Center School of Basic Medical SciencesLanzhou UniversityLanzhou730000PR China Institute of Health Data Science Lanzhou UniversityLanzhou730000PR China

Biodegradable metals are promising candidates for bone defect *** an evidence-based approach,this study investigated and analyzed the performance and degradation properties of biodegradable metals in animal models for bone defect repair to explore their potential clinical *** studies on bone defect repair with biodegradable metals in comparison with other traditional biomaterials were *** was carefully collected after identification of population,intervention,comparison,outcome,and study design(PICOS),and following the inclusion criteria of biodegradable metals in animal studies.30 publications on pure Mg,Mg alloys,pure Zn and Zn alloys were finally included after extraction from a collected database of 2543 publications.A qualitative systematic review and a quantitative meta-analysis were *** the heterogeneity in animal model,anatomical site and critical size defect(CSD),biodegradable metals exhibited mixed effects on bone defect repair and degradation in animal studies in comparison with traditional non-degradable metals,biodegradable polymers,bioceramics,and autogenous bone *** results indicated that there were limitations in the experimental design of the included studies,and quality of the evidence presented by the studies was very *** enhance clinical translation of biodegradable metals,evidence-based research with data validity is *** studies should adopt standardized experimental protocols in investigating the effects of biodegradable metals on bone defect repair with animal models.

关键词： Biodegradable metals Bone defect repair Animal model Systematic review and meta-analysis Regulatory science Safety and effectiveness

Occurrence and Damage of Ferrisia virgata Cockerell on Longan (Dimocarpus longgana Lour.) in Guangdong Province of China

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plant Diseases and Pests 2013年第1期4卷 13-14页

作者： Li Weicai He yanbiao Zhan Rulin Wang Yicheng shi Shengyou Wei Yongzan Southern Subtropical Crops Research Institute Chinese Academy of Tropical Agricultural Sciences

Ferrisia virgata （Cockerell） is a post with wide distribution and broad range of host plants, but apparently it has not yet known to be an important post in China. Survey on pests of longan （Dimocarpus longgana Lour. ） in Zhangjiang of Guangdong Province in 2011 found that F. virgata had caused serious damage on production of longan. The paper first reported damage status of F. virgata on longan and also preliminarily introduced field identification characterlstics and host plants of F. virgata reported.

关键词： Ferrisia virgata (Cockerell) Longan Guangdong New record

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

单模硫系光纤色散特性分析

光子学报 2000年第2期29卷 171-173页

作者：黎敏廖延彪施纯峥清华大学电子工程系北京100084

本文对目前红外光纤研究的热点 -硫系光纤独特的色散特性进行理论分析 .研究主要针对 As2 S3光纤的材料特性进行 .理论计算和分析显示 :As2 S3光纤的材料色散高达-1 0 0 ps/***以上 ,比硅基材料光纤高 1～ 2个数量级 ,可以与硅基光纤光... 详细信息

本文对目前红外光纤研究的热点 -硫系光纤独特的色散特性进行理论分析 .研究主要针对 As2 S3光纤的材料特性进行 .理论计算和分析显示 :As2 S3光纤的材料色散高达-1 0 0 ps/***以上 ,比硅基材料光纤高 1～ 2个数量级 ,可以与硅基光纤光栅相媲美 .特殊的色散特性。

关键词：硫系光纤色散光纤单模

在线全文

学校读者我要写书评

暂无评论

抑制光纤检波器系统光强波动影响的解调方法

红外与激光工程 2013年第6期42卷 1593-1600页

作者：王凯田长栋施清平王利威段发阶张敏廖延彪天津大学精密测试技术及仪器国家重点实验室天津300072 清华大学集成光电子学国家重点实验室北京100084 北京宇航系统工程研究所北京100076

基于海上油藏勘探领域的光纤检波器光电复合空分阵列系统,通过两路PGC干涉检波信号相除以构造非线性函数,提出了一种采用查找表实现该非线性函数解调的新方法。相比传统的两路PGC干涉检波信号线性组合的反正切解调方法,构造非线性函数... 详细信息

基于海上油藏勘探领域的光纤检波器光电复合空分阵列系统,通过两路PGC干涉检波信号相除以构造非线性函数,提出了一种采用查找表实现该非线性函数解调的新方法。相比传统的两路PGC干涉检波信号线性组合的反正切解调方法,构造非线性函数解调新方案不仅可以补偿生成载波时直接调制DFB光源带来的高频光强波动干扰,也可以抑制其他因素造成的光强随机波动给采用定常系统参数解调带来的影响。实验结果表明:内调制DFB激光器,采用非线性函数解调方案比线性组合方案在谐波抑制方面优势明显,两者HSR平均值相差达26.37 dB;当系统光强降低50%,非线性函数解调方案的结果 HSR平均值优于线性组合方案得到的结果,两者相差达17.53 dB。

关键词：光纤检波器相位生成载波光强波动伴生调幅非线性函数查找表