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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2015年第3期16卷 198-207页

作者： Xian-qing HU Jian CHENG Biao TANG Zhong-heng ZHANG Ke HUANG Yi-ping yanG yan-yan mao Ming ZHONG Shen-wen FU Department of Cardiovascular Medicine Jinhua Municipal Central Hospital Department of Critical Care Medicine Jinhua Municipal Central Hospital

Objective： To evaluate the clinical effect of postconditioning on patients with ST-elevation myocardial infarction （STEMI） treated with primary percutaneous coronary intervention （PCI）. Methods： Randomized controlled trials were identified by searching relevant databases published up to April 2nd, 2014. A meta-analysis of eligible studies was performed by Stata 12.0 and Review Manager 5.2 with a fixed-effect model. Results： Ten studies providing adverse cardiac events in a total of 1346 STEMI patients treated with primary PCI were identified. The occurrence of heart failure was significantly reduced in patients treated with postconditioning compared with usual care （risk ratio （RR） 0.533; 95% confidence intervals （CI） 0.368-0.770）, whereas non-fatal reinfarction slightly increased in the postconditioning group （RR 2.746; 95% CI 1.007-7.488）. No significant difference in total major adverse cardiac events （MACEs） was observed between the two groups （RR 0.876; 95% CI 0.671-1.144）. Conclusions： Postcondi- tioning in STEMI patients undergoing primary PCI significantly reduces the risk of heart failure, but fails to decrease the incidence of total MACEs and the risk of non-fatal reinfarction.

关键词： Myocardial infarction Postconditioning Coronary intervention

High Fe‑Loading Single‑Atom Catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial Therapy

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Nano-Micro Letters 2025年第2期17卷 187-203页

作者： Si Chen Fang Huang Lijie mao Zhimin Zhang Han Lin Qixin yan Xiangyu Lu Jianlin Shi Department of Cardiology Shanghai Tenth People’s HospitalSchool of MedicineTongji UniversityShanghai 200092People’s Republic of China Shanghai Institute of Ceramics Chinese Academy of SciencesShanghai 200050People’s Republic of China Shanghai Frontiers Science Center of Nanocatalytic Medicine School of MedicineTongji UniversityShanghai 200092People’s Republic of China

The current single-atom catalysts(SACs)for medicine still suffer from the limited active site ***,we develop a synthetic method capable of increasing both the metal loading and mass-specific activity of SACs by exchanging zinc with *** constructed iron SACs(h^(3)-FNC)with a high metal loading of 6.27 wt%and an optimized adjacent Fe distance of~4 A exhibit excellent oxidase-like catalytic performance without significant activity decay after being stored for six months and promising antibacterial ***,a“density effect”has been found at a high-enough metal doping amount,at which individual active sites become close enough to interact with each other and alter the electronic structure,resulting in significantly boosted intrinsic activity of single-atomic iron sites in h^(3)-FNCs by 2.3 times compared to low-and medium-loading ***,the overall catalytic activity of h^(3)-FNC is highly improved,with mass activity and metal mass-specific activity that are,respectively,66 and 315 times higher than those of commercial Pt/*** addition,h^(3)-FNCs demonstrate efficiently enhanced capability in catalyzing oxygen reduction into superoxide anion(O_(2)·^(−))and glutathione(GSH)*** in vitro and in vivo assays demonstrate the superior antibacterial efficacy of h^(3)-FNCs in promoting wound *** work presents an intriguing activity-enhancement effect in catalysts and exhibits impressive therapeutic efficacy in combating bacterial infections.

关键词： Nanocatalytic medicine Single-atom catalysts Reactive oxygen species(ROS) High metal loading Oxidase catalysis

RAPID DETERMINATION OF PROTEIN IN MILLET BY FOURIER TRANSFORM NEAR-INFRARED(FTNIR)DIFFUSE REFLECTANCE SPECTROSCOPY

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Chinese Chemical Letters 1990年第3期1卷 247-250页

作者： Le Ming SHI Zhi Hong XU Zhong Xiao PAN Zhi Liang LI Laboratory of Computer Chemistry,Institute of Chemical Metallurgy,Chinese Academy of Sciences,Beijing 100080 yan Lu yan mao JIN Central Laboratory,Beijing Agricultural University,Beijing 100094

In this paper,the Fourier transform near-infrared(FTNIR)diffuse reflectance spectroscopy is applied for the rapid determination of protein in *** partial least-squares(PLS)regression is successfully used as an effective multivariate calibration *** calibration set is composed of 20 standard millet samples that the protein contents were determined by the traditional Kjeldahl *** optimal model dimension is found to be 5 by cross-validation.22 millet samples were determined by the proposed FTNIR-PLS *** correlation coefficient between the concentration values obtained by the FTNIR-PLS method and the traditional Kjeldahl method is *** standard error of prediction(SEP)is 0.28% and the mean recovery is 100.2%.The proposed method has been successfully applied for the routine analysis of protein in about 10,000 grain samples.

关键词： PLS NIR FTNIR)DIFFUSE REFLECTANCE SPECTROSCOPY RAPID DETERMINATION OF PROTEIN IN MILLET BY FOURIER TRANSFORM NEAR-INFRARED

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我国特殊教育研究热点与前沿问题分析

当代教育与文化 2017年第2期9卷 20-25页

作者：董艳艳张茂聪山东英才学院山东济南250014 山东师范大学教育政策与管理研究中心山东济南250015

采用CITESPACEⅡ对近五年《中国特殊教育》刊载文献进行可视化分析,以高产出者、高被引者及研究机构为关键词,得出我国特殊教育核心研究群体,以北京师范大学、华东师范大学、南京特殊教育职业学院等为主的特殊教育核心研究机构;以高频... 详细信息

采用CITESPACEⅡ对近五年《中国特殊教育》刊载文献进行可视化分析,以高产出者、高被引者及研究机构为关键词,得出我国特殊教育核心研究群体,以北京师范大学、华东师范大学、南京特殊教育职业学院等为主的特殊教育核心研究机构;以高频关键词、中心度为节点,对关键词聚类分析,得出我国特殊教育研究热点主要有心理健康、随班就读、自闭症等;通过突变值分析,得出"中介作用"是我国特殊教育渐增型研究前沿。提出关注学生心理健康,关注国外特殊教育发展,加强跨机构及跨学科之间的合作创新等研究策略。

关键词：可视化特殊教育研究热点研究前沿

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电动汽车逆变器用散热器的优化设计

变流技术与电力牵引 2008年第4期 42-45页

作者：言艳毛南车株洲电力机车研究所有限公司湖南株洲412001

利用ICEPAK软件,全面地对逆变器的各种散热情况进行了分析,得出最佳散热方案,为散热器的设计提供了依据,改进的散热器现已应用于多款电动汽车。

关键词：逆变器散热器热分析电力电子

新能源电动汽车企业标准化管理与分析——以中车时代电动汽车股份有限公司为例

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中国标准化 2019年第19期 114-117页

作者：言艳毛中车时代电动汽车股份有限公司湘江新区分公司

本文对研制标准化工作在新能源电动汽车企业管理中的重要性进行了探讨,通过引入卡柯特定律,强调了"三化"的重要性,明确了"三化"的开展时机,剖析了标准化管理中存在的实际问题,并提出标准化管理的提升举措,并根据自身的工作经验,说明了... 详细信息

本文对研制标准化工作在新能源电动汽车企业管理中的重要性进行了探讨,通过引入卡柯特定律,强调了"三化"的重要性,明确了"三化"的开展时机,剖析了标准化管理中存在的实际问题,并提出标准化管理的提升举措,并根据自身的工作经验,说明了标准分析的重要性,并提出了标准分析的方法。

关键词：产品标准化三化标准体系标准分析

我国九省市男性生殖道感染发生率及其多水平影响因素分析

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生殖与避孕 2010年第3期30卷 187-192页

作者：毛燕燕蔡建华胡云俞华周维谨车焱上海市计划生育科学研究所上海200032 国家人口计生委培训交流中心北京100081 中国生殖健康家庭保健培训中心太仓215400 中国人口与发展研究中心北京100081

目的:了解我国不同地区男性生殖道感染(RTI)的发生率及其影响因素。方法:采用分层整群抽样的方法,在2009年调查我国九省市育龄男性家庭及其生殖健康状况。以对象自诉过去1年曾发生的RTI症状为分析指标,采用χ2及多水平logistic回归模型... 详细信息

目的:了解我国不同地区男性生殖道感染(RTI)的发生率及其影响因素。方法:采用分层整群抽样的方法,在2009年调查我国九省市育龄男性家庭及其生殖健康状况。以对象自诉过去1年曾发生的RTI症状为分析指标,采用χ2及多水平logistic回归模型进行统计分析。结果:共调查13794名育龄男性,其中6.1%自报过去1年中曾发生RTI感染症状,未婚者RTI发生率为2.8%,已婚者为6.8%。仅约50%的感染者曾经就医,未婚者就医和治愈率比已婚者低。多水平logistic模型分析表明,男性RTI的发生除与婚姻、职业及烟酒行为有关外,还与家庭饮用水类型、排烟措施相关。男性RTI发生存在明显的地区差异。结论:男性RTI发生水平较高但就诊率低,地区差异明显,预防重点为农村、家庭卫生条件差且有不良嗜好的已婚男性,RTI防治知识和患者治疗率亟待加强。

关键词：男性生殖道感染发生率影响因素多水平logistic模型

Potassium ions and cyano group modified g-C3N4 for effective generation of H2O2 through two-electron oxygen reduction

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Science China Chemistry 2025年第1期 192-200页

作者： Dongying Wang Shulan Pu Yongmin Chen Ke Lei Yujie Duan Linjiao mao Xuhui Zeng Xi Luo Yuntao Zhang Yuqin Dong Jin Zhong Zhang yan Sun School of Mechanical Engineering Chengdu University Department of Chemistry and Biochemistry University of California

Potassium ions （K+） doped graphitic carbon nitride （g-C3N4） was prepared by a thermal etching method using potassium hydroxide （KOH） as an ion *** transform infrared spectroscopy （FTIR） and X-ray photoelectron spectroscopy （XPS）results showed that the generation of the cyano group was detected while introducing K+.Under simulated sunlight irradiation,the sample with a K+doping amount of 10%showed the highest hydrogen peroxide （H2O2） generation rate of2,140.2μmol *** apparent quantum yield （AQY） at 400 nm and the solar-to-chemical conversion （SCC） are 4.35%and1.23%,respectively.K+acted as a bridge between g-C3N4layers,which enhanced charge transfer ***,the cyano group enhanced the adsorption capacity of protons （H+） and promoted the yield of *** catalyst exhibited excellent photocatalytic stability based on four-cycle *** addition,a mechanism study showed that superoxide radicals （·O2-）were the most important active species in the reaction *** production of H2O2was achieved through consecutive single-electron *** study deepens the understanding of the oxygen reduction reaction process and opens up a new venue for improving H2O2generation.

关键词：

同方期刊数据库

分子信标探针技术用于PCR检测诺卡氏菌SecA1基因

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中国人兽共患病学报 2017年第6期33卷 508-512页

作者：王颜颜夏茂宁明春艳黄劲刘涛华周兵康颖倩贵州医科大学微生物学教研室贵阳550025 贵州医科大学生化与分子生物学教研室贵阳550025

目的将诺卡氏菌属细菌的一段特异性DNA设计成分子信标探针,用于该细菌的PCR检测。方法将诺卡氏菌属细菌、戈登氏菌属细菌及红球菌属细菌菌株分别接种于脑心浸液琼脂培养基分离培养,观察其生长情况,提取菌株DNA作为扩增模板;设计诺卡氏... 详细信息

目的将诺卡氏菌属细菌的一段特异性DNA设计成分子信标探针,用于该细菌的PCR检测。方法将诺卡氏菌属细菌、戈登氏菌属细菌及红球菌属细菌菌株分别接种于脑心浸液琼脂培养基分离培养,观察其生长情况,提取菌株DNA作为扩增模板;设计诺卡氏菌属细菌基于secA1基因的特异性分子信标探针,在实时荧光定量PCR反应译体系中加入分子信标探针,PCR产物进行荧光信号检测。结果诺卡氏菌secA1基因经实时荧光定量PCR扩增后可产生阳性荧光信号,红球菌属细菌及戈登氏菌属细菌的secA1基因、阴性对照实验组及空白对照组经实时荧光定量PCR扩增后不产生荧光信号,为阴性。结论 secA1作为看家基因,是用来进行种水平的鉴定及系统进化研究非常理想的靶分子,而分子信标探针技术可以准确、快速、灵敏的进行诺卡氏菌secA1基因检测。

关键词：诺卡氏菌属 SecA1基因分子信标探针实时荧光定量PCR

Effects of comprehensive nutrition support on immune function,wound healing,hospital stay,and mental health in gastrointestinal surgery

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World Journal of Gastrointestinal Surgery 2024年第12期16卷 3737-3744页

作者： Ling Zhu Jun Cheng Fei Xiao yan-yan mao Department of Gastrointestinal Surgery Wuhan Fourth HospitalWuhan 430000Hubei ProvinceChina Department of Gastrointestinal Surgery Qianjiang Central HospitalQianjing 433100Hubei ProvinceChina

BACKGROUND Postoperative patients undergoing gastrointestinal surgery often encounter challenges such as low immune function,delayed wound healing owing to surgical trauma,and increased nutritional demands during *** To assess the effect of comprehensive nutritional support program on immune function and wound healing in patients undergoing gastrointestinal *** This retrospective comparative study included 60 patients who underwent gastrointestinal surgery,randomly assigned to either the experimental group(n=30)or the control group(n=30).The experimental group received comprehensive nutritional support,including a combination of enteral and parenteral nutrition,whereas the control group received only conventional comprehensive nutritional *** indicators included immune function markers(e.g.,white blood cell count,lymphocyte subsets),wound healing(wound infection rate,healing time),pain score[visual analog scale(VAS)score],and psychological status(anxiety score,depression score)7 days post-surgery)and duration of *** The immune function of patients in the experimental group was significantly better than that in the control *** white blood cell count was 8.52±1.19×109/L in the experimental group vs 6.74±1.31×109/L(P<0.05).The proportion of CD4+T cells was higher in the experimental group(40.09%±4.91%)than that in the control group(33.01%±5.08%)(P<0.05);the proportion of CD8+T cells was lower(21.79%±3.38%vs 26.29%±3.09%;P<0.05).The CD4+/CD8+ratio was 1.91±0.32 in the experimental group whereas 1.13±0.23 in the control group(P<0.05).The wound infection rate of the experi-mental group was significantly lower than that of the control group(10%vs 30%,P<0.05),and the wound healing time was shorter(10.35±2.42 days vs 14.42±3.15 days,P<0.05).The VAS score of the experimental group was 3.05±1.04,and that of the control group was 5.11±1.09(P<0.05);the anxiety score(Hamilton Anxiety Rating Scale)was 8.88±1.87,and that of the con

关键词： Comprehensive nutritional support Gastrointestinal surgery Immune function Wound healing Pain score Psychological score Hospital stay