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畜牧与兽医 2017年第9期49卷 121-124页

作者：徐学玉罗仁武王珂林燕吴德教育部抗病营养国家重点实验室四川农业大学动物营养研究所四川雅安625000 雅安市名山区农业局四川雅安625000

L-精氨酸是氮氧化物(NO)和多胺等生物活性物质合成的前体,具有改善繁殖能力、心血管功能、胃肠道发育及调控免疫功能等多种作用。本文就精氨酸对雄性繁殖能力的影响进行了论述,以期对雄性动物的养殖生产有一定的理论作用。

关键词： L-精氨酸雄性繁殖性能

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Sex-dependent alterations in extracellular vesicles linking chronic spinal cord injury to brain neuroinflammation and neurodegeneration

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Neural Regeneration Research 2025年第2期20卷 483-484页

作者： Yun Li Junfang wu Department of Anesthesiology&Shock Trauma and Anesthesiology Research(STAR)CenterUniversity of Maryland School of MedicineBaltimoreMDUSA

Traumatic spinal cord injury(SCI)is a devastating exogenous injury with long-lasting consequences and a leading cause of death and disability *** in assistive technology,rehabilitative interventions,and the ability to identify and intervene in secondary conditions have significantly increased the long-term survival rate of SCI patients,with some people even living well into their seventh or eighth *** survival changes have led neurotrauma researchers to examine how SCI interacts with brain *** health and epidemiological data showed that patients with long-term SCI can have a lower life expectancy and quality of life,along with a higher risk of comorbidities and complications.

关键词： alterations inflammation injury

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Investigation on the interaction of dispersed and elongated bubbles based on laser-induced fluorescence

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Optoelectronics Letters 2025年

作者： XUE Ting SHI Ruini LIU Jinshun WANG Haixia wu yan School of Electrical and Information Engineering， Tianjin University

The purpose of this paper is to investigate the interaction between dispersed and elongated bubbles in horizontal slug flow utilizing the laser-induced fluorescence method. A Segmentation method based on the fuzzy C-mean (FCM) algorithm is proposed to effectively separate elongated bubbles from the liquid phase， and an extreme value extraction method is developed to calculate the number of dispersed bubbles in front of the nose of elongated bubbles. Moreover， the velocity offsets of elongated bubbles with and without dispersed bubbles are calculated separately based on contour extraction. In addition， the effect of dispersed bubbles on the fluctuating offsets of the nose tip position and velocity of elongated bubbles are statistically investigated under different flow velocities. The experimental results show that the increase of the gas-liquid flow velocity exacerbates the radial deviation of the nose tip and the fluctuation of axial velocity.

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PVIIAD: industrial visual anomaly detection method based on partially visible image inpainting

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Optoelectronics Letters 2025年

作者： wu Qiliang FEI Dongce YAO Minghui NIU yan WANG Cong School of Aeronautics and Astronautics， Tiangong University School of Artificial Intelligence， Tiangong University

Industrial anomaly detection is dedicated to identifying and locating regions that deviate from the standard appearance. The prevailing approach achieves unsupervised anomaly detection through the reconstruction of images using autoencoders. Due to the simplistic structure of some abnormal regions， the autoencoder can effectively reconstruct these areas， consequently diminishing the model's anomaly detection capabilities. To address this issue， this paper transforms the reconstruction task into the inpainting-filling-reconstruction task to increase the reconstruction error between abnormal samples and normal samples. In PVIIAD， the masked regions inpainted by the filling network are used to fill in the input image， thereby achieving an effect similar to masking. Unlike typical masking processes， this approach retains partial authentic information in the input image， rendering it partially visible. This is beneficial for the reconstruction network to repair the masked areas. Due to the consistent structure between the masked region inpainted by the filling network and the normal region， the filled abnormal regions display a complex structure that has not been learned， making it difficult for the reconstruction network to reconstruct the abnormal regions. Experimental results indicate that PVIIAD performs better than other methods on both the MVTec AD dataset and the MVTec LOCO AD dataset.

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海带、江蓠浸渍光合细菌菌液后喂养九孔鲍的效果

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水产学报 2001年第2期25卷 136-140页

作者：严正凛吴萍茹高霞灵福建海洋研究所生物室!福建厦门361012

使用海带、江蓠浸渍光合细菌的不同浓度和时间对大小两种不同规格九孔鲍的生长效果进行试验。结果表明 ,光合细菌促进养成鲍的生长效果 ,因海带、江蓠浸渍光合细菌的浓度和时间而异 ,浸渍浓度越大 ,浸渍时间越长 ,则其促进生长作用越明... 详细信息

使用海带、江蓠浸渍光合细菌的不同浓度和时间对大小两种不同规格九孔鲍的生长效果进行试验。结果表明 ,光合细菌促进养成鲍的生长效果 ,因海带、江蓠浸渍光合细菌的浓度和时间而异 ,浸渍浓度越大 ,浸渍时间越长 ,则其促进生长作用越明显 ;海带、江蓠浸渍光合细菌的浓度和时间分别为 15 0× 10 6(V/V)和 3h～ 4h或 2 0 0× 10 6(V/V)和 2h～ 3h的试验组鲍的平均壳长增长率都比对照组提高了 5 %以上 ,最高提高 11.5 %左右(P <0 .0 5 )。

关键词：九孔鲍光合细菌海带江蓠浸渍喂养

Deletion of FK506 binding protein 12.6 causes age-dependent heart failure

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Deletion of FK506 binding protein 12.6 causes age-dependent ...

Threonine and tryptophan supplementation mitigate porcine respiratory and reproductive syndrome(PRRS) vaccination induced growth slowness of growing pigs

第八届海峡两岸心血管科学研讨会

作者： Qi Yuan,Zheng Chen,Cong-yan Pan,Bin Wei,Ying-long Tong, Ying-xiao Chen,yan-yun wu,lin Miao,Guang-ju Ji (National Laboratory of Biomacromolecules,Institute of Biophysics,Chinese Academy of Sciences,15 Datun Rd,Beijing 100101,China)

Cytosolic Ca is a key regulator of excitation -contraction coupling in myocardium.A disturbance of the intracellular Ca homeostasis is one of the key factors for the contractile dysfunction in heart failure (HF).Moreover,increased sarcoplasmic reticulum(SR) Ca leak via the cardiac ryanodine receptor/calcium release channel(RyR2) is thought to play a role in HF *** studies indicate that FK506 binding protein 12.6(FKBP126) plays as important role in regulating in SR Ca content and maintaining the intracellular Ca *** of FKBP12.6 either leads to cardiac hypertrophy or heart sudden *** this study,we used FKBP12.6 knockout mice to investigate the role of this protein in HF pathogenesis. ER Ca load examination displayed a normal content in 8 - 12 week - old knockout(KO) and wild-type (WT) mice,while a significant lower content in 48 - 60 week - old KO mice compared to that in WT mice;the ratio of asynchronous Ca transient was greatly higher in KO *** time PCR study showed that expression of RyR2 and IPR2 was markedly changed in old - stage KO male mice compared to that of WT,namely,RyR2 was up - regulated and IPR2 was down - regulated with *** vivo echocardiographic assessments demonstrated that the direct echocardiographic parameter left ventricular posterior wall thickness (LVPW),left ventricular anterior wall(LVAW),and left ventricular mass(LVM) in 8 - 12 week - old male KO mice were significantly larger than those of WT mice(P<0.01 for each parameter).Left ventricular functional parameters fractional shortening(FS) and ejection fraction(EF) were higher in KO mice than those of WT mice(P<0.05).In contrary to younger stage,there were no significant differences of LVPW, LVAW,and LVM in 48 - 60 week - old KO and WT male ***,the FS and EF were greatly lower in KO mice than those of WT(P<0.01).Electrocardiogram(ECG) measurement suggested that both KO and WT mice exhibited a normal ECG in 8 - 12 week - old age;the 48 -

关键词： FKBP12.6 deletion calcium disturbance age-dependent heart failure

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Threonine and tryptophan supplementation mitigate porcine re...

赖氨酸辅助高分散金粒子修饰氮掺杂TiO_2纳米管催化剂的合成及光催化性能

低碳经济与高效养殖——第六次全国饲料营养学术研讨会暨动物营养学分会成立三十周年大会

作者： Shen Jie,Zhengfeng Fang,Yingfei Zhao,yan lin,De wu~* (Key Laboratory for Animal Disease Resistance Nutrition of Ministry of Education of China,Institute of Animal Nutrition,Sichuan Agricultural University,Ya’an 625014,China)

The objective of this study was to determine whether Thr and Trp-rich(TTR) diet would benefit growing pigs vaccinated with porcine respiratory and reproductive syndrome(PRRS) ***-six growing pigs(29 kg BW) were fed either a conventional(CON) diet with Lys:Thr:Trp at 100:64:18(n=13),or a TTR diet with Lys:Thr:Trp at 100:80:26(n=13),for 70The objective of this study was to determine whether Thr and Trp-rich(TTR) diet would benefit growing pigs vaccinated with porcine respiratory and reproductive syndrome(PRRS) ***-six growing pigs(29 kg BW) were fed either a conventional(CON) diet with Lys:Thr:Trp at 100:64:18(n=13),or a TTR diet with Lys:Thr:Trp at 100:80:26(n=13),for 70

关键词： growing pigs PRRS vaccination growth performance blood parameters

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高等学校化学学报 2016年第11期37卷 2034-2042页

作者：安会琴于育才闫琳吴婷婷李晓峰贺晓凌赵莉芝黄唯平天津工业大学环境与化学工程学院省部共建分离膜与膜过程国家重点实验室天津300387 天津工业大学材料科学与工程学院天津300387 南开大学先进能源材料化学教育部重点实验室天津300071

通过溶胶-凝胶法联合水热合成法制备了氮掺杂TiO_2纳米管,并以该纳米管为载体,采用绿色无毒的赖氨酸作为链接剂和螯合剂,一步实现金粒子在TiO_2纳米管上的高度分散,制备得到高分散金粒子修饰氮掺杂TiO_2纳米管催化剂(Au/N-TiO_2纳米管)... 详细信息

通过溶胶-凝胶法联合水热合成法制备了氮掺杂TiO_2纳米管,并以该纳米管为载体,采用绿色无毒的赖氨酸作为链接剂和螯合剂,一步实现金粒子在TiO_2纳米管上的高度分散,制备得到高分散金粒子修饰氮掺杂TiO_2纳米管催化剂(Au/N-TiO_2纳米管).表征了产物的形貌、结构、光学特性及组成,通过紫外光下甲基橙水溶液的光降解率评价产物的光催化活性,讨论了氮掺杂量、金负载量、赖氨酸及焙烧对合成催化剂光催化性能的影响.结果显示,在赖氨酸存在下,金粒子在TiO_2纳米管上呈高度分散状态,未发生聚集.且与纯TiO_2纳米管相比,Au/N-TiO_2纳米管显示出更高的光催化活性.Au/N-TiO_2纳米管的高催化活性是由于氮掺杂后引起的TiO_2带隙能窄化、金粒子在载体上的高分散状态及金与TiO_2形成的肖特恩势垒引起的低电子-空穴复合率共同作用导致的.

关键词：二氧化钛纳米管氮掺杂金粒子赖氨酸光降解甲基橙

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[Impact of arsenic exposure on the hepatic metabolic molecular network in obese pregnant mice using metabolomics and proteomics]

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Se pu = Chinese journal of chromatography 2025年第1期43卷 50-59页

作者： Li-Jing Cai yan Wang Jun-Feng Tan Hai-Xia Zhou Shi-Jia Liang yan wu Jie Zhang School of Public Health Xiamen University Xiamen 361102 China. School of Public Health Fujian Medical University Fuzhou 350122 China.

Arsenic is a ubiquitous environmental toxin that can affect normal physiological processes. Although the health impacts of arsenic have been investigated, its influence on hepatic metabolism in obese pregnant women and the underlying mechanisms remain unclear. Multi-omics analysis, including metabolomics and proteomics, can improve the understanding of arsenic-induced hepatotoxicity in obese pregnant women. This study aimed to investigate the adverse effects of gestational arsenic exposure on hepatic metabolism in high-fat-diet-induced obese pregnant mice. Following arsenic exposure during pregnancy, the liver tissue was evaluated comprehensively using metabolomics and proteomics techniques combined with pathological and biochemical analyses. Arsenic exposure not only significantly increased lipid accumulation in the livers of obese pregnant mice but also elevated inflammatory factors and oxidative stress markers. Specifically, histopathological examination revealed more steatosis, inflammatory cell infiltration, and hepatocyte ballooning in the livers of arsenic-exposed mice than in those of controls. These changes indicate that arsenic exposure exacerbates hepatic lipid accumulation and induces liver damage in the context of obesity. Metabolomic analysis provided further insight into the metabolic-level disruption caused by arsenic exposure. Significant changes were observed in lipid metabolism pathways, particularly the arachidonic acid metabolism pathway. As arachidonic acid and its metabolites play important roles in inflammation and oxidative stress, this pathway may be critical in arsenic-induced hepatotoxicity. Additionally, proteomic analysis showed differences in the expression levels of several key proteins involved in lipid synthesis, oxidative stress, and inflammatory response. Notably, oxidative-stress-related proteins, including glutathione peroxidase 4 (GPX4), were upregulated, suggesting an increased oxidative burden. In summary, there are complex i

关键词： arsenic liver metabolomics obesity pregnant mice proteomics

Hourglass-GCN for 3D Human Pose Estimation Using Skeleton Structure and View Correlation

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Computers, Materials & Continua 2025年第1期82卷 173-191页

作者： Ange Chen Chengdong wu Chuanjiang Leng Faculty of Robot Science and Engineering Northeastern UniversityShenyang110169China

Previous multi-view 3D human pose estimation methods neither correlate different human joints in each view nor model learnable correlations between the same joints in different views explicitly,meaning that skeleton structure information is not utilized and multi-view pose information is not completely ***,existing graph convolutional operations do not consider the specificity of different joints and different views of pose information when processing skeleton graphs,making the correlation weights between nodes in the graph and their neighborhood nodes *** Graph Convolutional Networks(GCNs)cannot extract global and deeplevel skeleton structure information and view correlations *** solve these problems,pre-estimated multiview 2D poses are designed as a multi-view skeleton graph to fuse skeleton priors and view correlations explicitly to process occlusion problem,with the skeleton-edge and symmetry-edge representing the structure correlations between adjacent joints in each viewof skeleton graph and the view-edge representing the view correlations between the same joints in different *** make graph convolution operation mine elaborate and sufficient skeleton structure information and view correlations,different correlation weights are assigned to different categories of neighborhood nodes and further assigned to each node in the *** on the graph convolution operation proposed above,a Residual Graph Convolution(RGC)module is designed as the basic module to be combined with the simplified Hourglass architecture to construct the Hourglass-GCN as our 3D pose estimation ***-GCNwith a symmetrical and concise architecture processes three scales ofmulti-viewskeleton graphs to extract local-to-global scale and shallow-to-deep level skeleton features *** results on common large 3D pose dataset Human3.6M and MPI-INF-3DHP show that Hourglass-GCN outperforms some excellent methods in 3D pose estimati

关键词： 3D human pose estimation multi-view skeleton graph elaborate graph convolution operation Hourglass-GCN