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Epidemiological characteristics and risk factors of nosocomial carbapenem-resistant Enterobacteriaceae infections in children

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Chinese Medical Journal 2020年第22期133卷 2756-2758页

作者： Zhe li Xi-Xi lin Cai-Xia liu Wen-Jing Ye Pei-Ning liu hai-yan li lin Dong Department of Pediatrics The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical UniversityWenzhouZhejiang 325000China Department of Pharmacy The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical UniversityWenzhouZhejiang 325000China Department of Clinical Microbiological Laboratory The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical UniversityWenzhouZhejiang 325000China

Carbapenem-resistant Enterobacteriaceae(CRE)have spread worldwide as a global threat and CRE infection is associated with a significant ***,data on epidemiology and treatment of CRE infection in children are comparatively lacking.[1]Therefore,we retrospectively conducted a matched case-control study to summarize the epidemiological characteristics,risk factors,treatment,and outcomes of nosocomial CRE infections in a children patient population,and also to identify the antimicrobial resistance and resistance genotyping of CRE isolates.

关键词： infections epidemiology treatment

Synergistic effect of Co and Co_(6)Mo_(6)C for electroreduction of nitrate to ammonia on Co-MOF derived Co_(6)Mo_(6)C/Co/NC

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Nano Research 2024年第7期17卷 5807-5816页

作者： Xinyan Wang Yue Cao yan hai Xiaoman li Min Luo State Key Laboratory of High-efficiency Utilization of Coal and Green Chemical Engineering School of Chemistry and Chemical EngineeringNingxia UniversityYinchuan 750021China

Electrocatalytic nitrate reduction reaction(e-NO_(3)RR)offers a promising alternative method for nitrogen cycling and ammonia(NH3)production under ambient ***,the method is still in the dilemma of lowering the reaction overpotential and increasing the reaction *** successfully developed the composition-adjustable Co_(6)Mo_(6)C/Co/N-doped carbon(NC)catalysts by in situ carbonization of Co-based metal-organic framework(MOF)with the constrained phosphomolybdic *** adjusting the ratio of Co0 and Co_(6)Mo_(6)C,Co_(6)Mo_(6)C/Co/NC-3 could satisfy both NO_(3)−conversion at low potential and NH_(x)hydrogenation,and synthesize ammonia efficiently through the synergistic effect of Co0 and Co_(6)Mo_(6)*** achieved an ammonia yield rate as 1233.2μg·h^(−1)·mgcat^(−1)and Faradaic efficiency of NH4+93.6%at−0.33 V *** hydrogen electrode(RHE).Importantly,density functional theory(DFT)calculations and experimental results have demonstrated for the first time the excellent adsorption of nitrite(NO_(2)^(−))by the Mo sites of Co_(6)Mo_(6)C during e-NO_(3)RR,avoiding the undesirable accumulation of NO_(2)^(−).

关键词： synergistic effect nitrate electroreduction Co_(6)Mo_(6)C ammonia synthesis

Operative link on gastritis assessment stage is an appropriate predictor of early gastric cancer

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World Journal of Gastroenterology 2016年第13期22卷 3670-3678页

作者： Ying Zhou hai-yan li Jing-Jing Zhang Xiao-Yu Chen Zhi-Zheng Ge Xiao-Bo li Division of Gastroenterology and Hepatology Ren Ji Hospital School of Medicine Shanghai Jiao Tong University Shanghai Institute of Digestive Disease

AIM: To assess the predictive value of Operative link on Gastritis Assessment (OLGA) and Operative link on Gastric Intestinal Metaplasia Assessment (OLGIM) stages in gastric ***: A prospective study was conducted with 71 patients with early gastric cancer (EGC) and 156 patients with non-EGC. All patients underwent endoscopic examination and systematic biopsy. Outcome measures were assessed and compared, including the Japanese endoscopic gastric atrophy (EGA) classification method and the modified OLGA method as well as the modified OLGIM method. Helicobacter pylori (H. pylori) status was determined for all study participants. Stepwise logistic regression modeling was performed to analyze correlations between EGC and the EGA, OLGA and OLGIM ***: For patients with EGC and patients with non-EGC, the proportions of moderate-to-severe EGA cases were 64.8% and 44.9%, respectively (P = 0.005), the proportions of OLGA stages III-IV cases were 52.1% and 22.4%, respectively (P ling showed significant correlations between EGC and moderate-to-severe EGA (OR = 1.95, 95% CI: 1.06-3.58, P = 0.031) and OLGA stages III-IV (OR = 3.14, 95%CI: 1.71-5.81, P litate early detection of gastric cancer.

关键词： Early gastric cancer Operative link on Gastritis Assessment/Operative link on Gastric Intestinal Metaplasia Assessment stage Endoscopic gastric atrophy classification Screening Endoscopy

Serum 25-hydroxyvitamin D deficiency predicts poor outcomes among acute ischemic stroke patients receiving intravenous thrombolysis

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Chinese Medical Journal 2019年第4期132卷 491-494页

作者： Lei Wei Chuan Chen Yong-Qiang Dai li Ding hai-yan li yan-Jun lin Hao-Tian WU Zhen WU Zheng-Qi Lu Department of Neurology The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong 510630China Department of Neurosurgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong 510630China Department of Pathology The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong 510080China Department of Neurology The Seventh Affiliated Hospital of Sun Yat-sen UniversityShenzhenGuangdong 518107China

To the Editor:Ischemic stroke remains a major cause of death and disability worldwide and contributes to the rising costs of health *** therapy with tissue plasminogen activator (tPA,alteplase)is beneficial for the treatment of acute ischemic ***,only 40%to 50%of stroke patients show a significant improvement after *** addition,the use of alteplase is restricted because symptomatic intracranial hemorrhase (slCH)occurs in 1.7%to 6.4%of treated patients.[1] 25-hydroxyvitamin D (25(OH)D),which is the major circulating metabolite of vitamin D,has been confirmed to be closely related to cerebrovascular disease (CVD).A series of studies indicated that vitamin D deficiency was associated with an increased risk of ischemic stroke,high stroke severity and poor functional outcomes.

关键词： Serum 25-hydroxyvitamin deficiency

Research on casing deformation prevention technology based on cementing slurry system optimization

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Petroleum Science 2024年第2期21卷 1231-1240页

作者： yan yan Meng Cai Wen-hai Ma Xiao-Chuan Zhang li-Hong Han Yong-Hong liu State Key Laboratory for Performance and Structure Safety of Petroleum Tubular Goods and Equipment Materials CNPC Tubular Goods Research InstituteXi©an710077ShaanxiChina College of Mechanical and Electrical Engineering China University of Petroleum(East China)Qingdao266580ShandongChina Shale Gas Evaluation and Exploitation Key Laboratory of Sichuan Province Chengdu610095SichuanChina CNPC Daqing Oilfield Company Daqing163453HeilongjiangChina

The casing deformation prevention technology based on the optimization of cement slurry is proposed to reduce the casing deformation of shale oil and gas wells during hydraulic fracturing. In this paper, the fracture mechanism of hollow particles in cement sheath was firstly analyzed by discrete element method, and the effect of hollow particles in cement on casing deformation was investigated by laboratory experiment method. Finally, field test was carried out to verify the improvement effect of the casing deformation based on cement slurry modification. The results show that the formation displacement can be absorbed effectively by hollow particles inside the cement transferring the excessive deformation away from casing. The particles in the uncemented state provide deformation space during formation slipping. The casing with diameter of 139.7 mm could be passed through by bridge plug with the diameter of 99 mm when the mass ratio of particle/cement reaches 1:4. According to the field test feedback, the method based on optimization of cement slurry can effectively reduce the risk of casing deformation, and the recommended range of hollow microbeads content in the cement slurry is between 15% and 25%.

关键词： Cement slurry Hollow ceramsite Casing deformation Formation slip Field test

Intravenous leiomyomatosis with different surgical approaches:Three case reports

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World Journal of Clinical Cases 2019年第3期7卷 347-356页

作者： Jie He Zheng-Bo Chen San-Ming Wang Mu-Biao liu Zhi-Gang li hai-yan li Gang Zhao Department of Cardiovascular Surgery Guangdong Cardiovascular InstituteGuangdong General Hospital Guangdong Academy of Medical Sciences Department of Vascular Surgery Guangdong Cardiovascular Institute Guangdong General Hospital Guangdong Academy of Medical Sciences Department of Gynecology and Obstetrics Guangdong General Hospital Guangdong Academy of Medical Sciences

BACKGROUND Intravenous leiomyomatosis(IVL) is a rare and complicated disease, which requires surgery by a multidisciplinary team. However, the optimal surgical approach has not been *** SUMMARY Here we report three cases of IVL treated with different surgical approaches. All patients presented with circulation symptoms. Two patients had lower extremity edema and the other had cardiopalmus. The diagnosis of IVL was confirmed based on the imagining examinations and pathological findings. All patients underwent surgical treatment and were discharged without any *** Preoperative examination is crucial for surgical planning and surgical approach is dependent on the patient's condition and tumor involvement.

关键词： Intravenous leiomyomatosis Surgery Cardiac tumors Case report Minimally-invasive

Cloning of a Vacuolar H^+-pyrophosphatase Gene from the Halophyte Suaeda corniculata whose Heterologous Overexpression Improves Salt,Saline-alkali and Drought Tolerance in Arabidopsis

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Journal of Integrative Plant Biology 2011年第9期53卷 731-742页

作者： liang liu Ying Wang Nan Wang Yuan-Yuan Dong Xiu-Duo Fan Xiu-Ming liu Jing yang hai-yan li Ministry of Education Engineering Research Center of Bioreactor and Pharmaceutical Development Jilin Agricultural UniversityChangchun 130118China College of life Sciences Jilin Agricultural UniversityChangchun 130118China

Salt,saline-alkali conditions,and drought are major environmental factors limiting plant growth and *** vacuolar H＋-translocating inorganic pyrophosphatase（V-H＋-PPase） is an electrogenic proton pump that translocates protons into vacuoles in plant *** of V-H＋-PPase increases in plants under a number of abiotic stresses,and is thought to have an important role in adaptation to abiotic *** this work,we report the isolation and characterization of the gene,ScVP,encoding a vacuolar inorganic pyrophosphatase（V-H＋-PPase） from the halophyte,Suaeda *** reverse transcription-polymerase chain reaction analysis showed that ScVP was induced in roots,stems and leaves under treatment with salt,saline-alkali and *** with wild-type（WT） Arabidopsis,transgenic plants overexpressing ScVP accumulated more Na＋ in leaves and roots,and showed increased tolerance to high salinity,saline-alkali and drought *** germination percentage of transgenic Arabidopsis seeds was higher than that of WT seeds under the abiotic *** root length of transgenic plants under salt stress was longer than that of WT ***,the rate of water loss during drought stress was higher in WT than in transgenic ***,these results indicate that ScVP plays an important role in plant tolerance to salt,saline-alkali and drought stress.

关键词： drought H^+-pyrophosphatase salt saline-alkali Suaeda corniculata.

Comparison of commonly used retrograde tracers in rat spinal motor neurons

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Neural Regeneration Research 2015年第10期10卷 1700-1705页

作者： You-lai Yu hai-yan li Pei-xun Zhang Xiao-feng Yin Na Han Yu-hui Kou Bao-guo Jiang Department of Trauma and Orthopedics Peking University People’s Hospital Department of Gastroenterology Weifang People’s Hospital

The purpose of this study was to investigate the effect of four fluorescent dyes, True Blue（TB）, Fluoro-Gold（FG）, Fluoro-Ruby（FR）, and 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate（Di I）, in retrograde tracing of rat spinal motor neurons. We transected the muscle branch of the rat femoral nerve and applied each tracer to the proximal stump in single labeling experiments, or combinations of tracers（FG-Di I and TB-Di I） in double labeling experiments. In the single labeling experiments, significantly fewer labeled motor neurons were observed after FR labeling than after TB, FG, or Di I, 3 days after tracer application. By 1 week, there were no significant differences in the number of labeled neurons between the four groups. In the double-labeling experiment, the number of double-labeled neurons in the FG-Di I group was not significantly different from that in the TB-Di I group 1 week after tracer application. Our findings indicate that TB, FG, and Di I have similar labeling efficacies in the retrograde labeling of spinal motor neurons in the rat femoral nerve when used alone. Furthermore, combinations of Di I and TB or FG are similarly effective. Therefore, of the dyes studied, TB, FG and Di I, and combinations of Di I with TB or FG, are the most suitable for retrograde labeling studies of motor neurons in the rat femoral nerve.

关键词： nerve regeneration tracing efficacy fluorescent tracers retrograde tracing femoral nerve motor neurons

Quantum Mechanical Nature in liquid NMR Quantum Computing

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Communications in Theoretical Physics 2002年第3期38卷 305-308页

作者： LONG Gui-Lu yan hai-yang li yan-Song TU Chang-Cun ZHU Sheng-Jiang RUAN Dong SUN yang TAO Jia-Xun CHEN Hao-Ming Department of Physics Tsinghua University Beijing 100084 China Laboratory for Quantum Computation and Quantum Measurement Beijing 100084 China Center for Atomic and Molecular Nano-Sciences Tsinghua University Beijing 100084 China Institute of Theoretical Physics the Chinese Academy of Sciences Beijing 100080 China Department of Physics Tsinghua University Beijing 100084 ChinaLaboratory for Quantum Computation and Quantum Measurement Beijing 100084 China Department of Physics Tsinghua University Beijing 100084 ChinaLaboratory for Quantum Computation and Quantum Measurement Beijing 100084 China Department of Physics Tsinghua University Beijing 100084 ChinaLaboratory for Quantum Computation and Quantum Measurement Beijing 100084 China Department of Physics Tsinghua University Beijing 100084 China Department of Physics Tsinghua University Beijing 100084 China Department of Physics Tsinghua University Beijing 100084 China Laboratory for Quantum Computation and Quantum Measurement Beijing 100084 China Department of Physics and Astronomy University of Tennessee Knoxville Tennessee 37996 USA Department of Chemistry Tsinghua University Beijing 100084 China Department of Physics Tsinghua University Beijing 100084 China

The quantum nature of bulk ensemble NMR quantum computing the center of recent heated debate,is addressed. Concepts of the mixed state and entanglement are examined, and the data in a two-qubit liquid NMRquantum computation are analyzed. The main points in this paper are: i) Density matrix describes the "state" of anaverage particle in an ensemble. It does not describe the state of an individual particle in an ensemble; ii) Entanglementis a property of the wave function of a microscopic particle (such as a molecule in a liquid NMR sample), and separabilityof the density matrix cannot be used to measure the entanglement of mixed ensemble; iii) The state evolution in bulk-ensemble NMRquantum computation is quantum-mechanical; iv) The coefficient before the effective pure state densitymatrix, e, is a measure of the simultaneity of the molecules in an ensemble. It reflects the intensity of the NMR signaland has no significance in quantifying the entanglement in the bulk ensemble NMR system. The decomposition of thedensity matrix into product states is only an indication that the ensemble can be prepared by an ensemble with theparticles unentangled. We conclude that effective-pure-state NMR quantum computation is genuine, not just classicalsimulations.

关键词： quantum mechanical nature, NMR quantum computing, mixed state, entanglement