检索结果-南通市图书馆

Ferrodifferentiation regulates neurodevelopment via ROS generation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2023年第8期66卷 1841-1857页

作者： Shiyang chang Peina Wang Yingying Han Qiang Ma Zeyuan Liu Suijuan zhong Yufeng Lu Ruiguo Chen Le Sun Qian Wu Guofen Gao Xiaoqun Wang yan-zhong chang Laboratory of Molecular Iron Metabolism Ministry of Education Key Laboratory of Molecular and Cellular BiologyHebei Key Laboratory of Animal PhysiologyBiochemistryand Molecular BiologyCollege of Life SciencesHebei Normal UniversityShijiazhuang 050024China College of Basic Medicine Hebei Medical UniversityShijiazhuang 050017China State Key Laboratory of Brain and Cognitive Science CAS Center for Excellence in Brain Science and Intelligence Technology(Shanghai)Institute of BiophysicsChinese Academy of Sciences(CAS)BNU IDG/McGovern Institute for Brain ResearchBeijing 100101China State Key Laboratory of Cognitive Neuroscience and Learning Beijing Normal UniversityBeijing 100875China Beijing Institute of Brain Disorders Laboratory of Brain DisordersMinistry of Science and TechnologyCollaborative Innovation Center for Brain DisordersCapital Medical UniversityBeijing 100069China

Iron is important for life,and iron deficiency impairs development,but whether the iron level regulates neural differentiation remains *** this study,with iron-regulatory proteins(IRPs)knockout embryonic stem cells(ESCs)that showed severe iron deficiency,we found that the Pax6-and Sox2-positive neuronal precursor cells and Tuj1 fibers in IRP1^(-/-)IRP2^(-/-)ESCs were significantly decreased after inducing neural ***,in vivo study showed that the knockdown of IRP1 in IRP2^(-/-)fetal mice remarkably affected the differentiation of neuronal precursors and the migration of *** findings suggest that low intracellular iron status significantly inhibits *** supplementing IRP1^(-/-)IRP2^(-/-)ESCs with iron,these ESCs could differentiate *** investigations revealed that the underlying mechanism was associated with an increase in reactive oxygen species(ROS)production caused by the substantially low level of iron and the downregulation of iron-sulfur cluster protein ISCU,which,in turn,affected the proliferation and differentiation of stem ***,the appropriate amount of iron is crucial for maintaining normal neural differentiation that is termed ferrodifferentiation.

关键词： IRPs ESCs iron differentiation neurodevelopment ROS

Generic Modeling and Control Framework for Power Systems Dominated by Power Converters Connected Through a Passive Transmission and Distribution Grid

在线全文

学校读者我要写书评

暂无评论

CSEE Journal of Power and Energy Systems 2024年第1期10卷 292-301页

作者： Qing-chang zhong Marcio Stefanello Department of Electrical and Computer Engineering Illinois Institute of TechnologyChicagoIL 60616USA Syndem LLC USA.M.Stefanello is with the Fundacao Universidade Federal do Pampa at AlegreteRS97546-550Brazil

In this paper,a compact mathematical model having an elegant structure,together with a generic control framework,are proposed for generic power systems dominated by power converters that are interconnected through a passive transmission and distribution(T&D)grid,by adopting the port-Hamiltonian(pH)systems theory and the fundamental circuit *** models of generic T&D lines are developed and then the model of a generic T&D grid is *** the proposed control framework,the controlled converters are proven to be passive and Input-to-State Stable(ISS).The compact mathematical model is scalable and can be applied to power systems with multiple power electronic converters with generic passive controllers,passive local loads,and different types of passive T&D lines connected in a meshed configuration without self-loops,so it is very ***,the resulting power system is proven to be ISS as *** analysis is carried out without assumptions on constant frequency/voltage,constant loads,and/or lossless networks,except the need of passivity for all parts involved,and without using the Clarke/Park transformations or the graph *** simplify the presentation,three-phase balanced systems are adopted but the results can be easily adapted for single-phase or unbalanced three-phase systems.

关键词： Input-to-State Stable(ISS) passivity,portHamiltonian(pH)systems Power electronic converters dominated power systems Synchronized and Democratized(SYNDEM)grid architecture

BSEC Method for Unveiling Open Clusters and its Application to Gaia DR3:83 New Clusters

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2024年第5期24卷 169-184页

作者： zhong-Mu Li Cai-yan Mao Institute of Astronomy and Information Dali UniversityDali 671003China

Open clusters(OCs) are common in the Milky Way, but most of them remain undiscovered. There are numerous techniques, including some machine-learning algorithms, available for the exploration of OCs. However, each method has its limitations and therefore, different approaches to discovering OCs hold significant values. We develop a comprehensive approach method to automatically explore the data space and identify potential OC candidates with relatively reliable membership determination. This approach combines the techniques of Hierarchical Density-Based Spatial Clustering of Applications with Noise, Gaussian mixture model, and a novel cluster member identification technique, color excess constraint. The new method exhibits efficiency in detecting OCs while ensuring precise determination of cluster memberships. Because the main feature of this technique is to add an extra constraint(EC) for the members of cluster candidates using the homogeneity of color excess,compared to typical blind search codes, it is called Blind Search-Extra Constraint(BSEC) method. It is successfully applied to the Gaia Data Release 3, and 83 new OCs are found, whose color–magnitude diagrams(CMDs) are fitted well to the isochrones. In addition, this study reports 621 new OC candidates with discernible main sequence or red giant branch. It is shown that BSEC technique can discard some false negatives of previous works, which takes about three percentage of known clusters. It shows that as an EC, the color excess(or twocolor) constraint is useful for removing fake cluster member stars from the clusters that are identified from the positions and proper motions of stars, and getting more precise CMDs, when differential reddening of member stars of a cluster is not large(e.g., ΔE(G_(BP)-G_(RP)) < 0.5 mag). It makes the CMDs of 15% clusters clearer(in particular for the region near turnoff) and therefore is helpful for CMD and stellar population studies. Our result suggests that the color excess con

关键词： Galaxy stellar content-(Galaxy:)open clusters and associations general-stars fundamental parameters

An Electrochemical Perspective of Aqueous Zinc Metal Anode

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2024年第1期16卷 274-312页

作者： Huibo yan Songmei Li Jinyan zhong Bin Li School of Materials Science and Engineering Beihang UniversityBeijing 100191People’s Republic of China

Based on the attributes of nonflammability,environmental benignity,and cost-effectiveness of aqueous electrolytes,as well as the favorable compatibility of zinc metal with them,aqueous zinc ions batteries(AZIBs)become the leading energy storage candidate to meet the requirements of safety and low ***,aqueous electrolytes,acting as a double-edged sword,also play a negative role by directly or indirectly causing various parasitic reactions at the zinc anode *** reactions include hydrogen evolution reaction,passivation,and dendrites,resulting in poor Coulombic efficiency and short lifespan of AZIBs.A comprehensive review of aqueous electrolytes chemistry,zinc chemistry,mechanism and chemistry of parasitic reactions,and their relationship is ***,the understanding of strategies for suppressing parasitic reactions from an electrochemical perspective is not profound *** this review,firstly,the chemistry of electrolytes,zinc anodes,and parasitic reactions and their relationship in AZIBs are deeply ***,the strategies for suppressing parasitic reactions from the perspective of enhancing the inherent thermodynamic stability of electrolytes and anodes,and lowering the dynamics of parasitic reactions at Zn/electrolyte interfaces are ***,the perspectives on the future development direction of aqueous electrolytes,zinc anodes,and Zn/electrolyte interfaces are presented.

关键词： Aqueous zinc ions batteries Parasitic reactions Aqueous electrolyte Zinc anode

Abnormal State Detection in Lithium-ion Battery Using Dynamic Frequency Memory and Correlation Attention LSTM Autoencoder

在线全文

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2024年第8期140卷 1757-1781页

作者： Haoyi zhong Yongjiang Zhao chang Gyoon Lim Department of Computer Engineering Chonnam National UniversityYeosu59626South Korea

This paper addresses the challenge of identifying abnormal states in Lithium-ion Battery(LiB)time series *** the energy sector increasingly focuses on integrating distributed energy resources,Virtual Power Plants(VPP)have become a vital new framework for energy *** are key in this context,owing to their high-efficiency energy storage capabilities essential for VPP ***,LiBs are prone to various abnormal states like overcharging,over-discharging,and internal short circuits,which impede power transmission *** methods for detecting such abnormalities in LiB are too broad and lack precision for the dynamic and irregular nature of LiB *** response,we introduce an innovative method:a Long Short-Term Memory(LSTM)autoencoder based on Dynamic Frequency Memory and Correlation Attention(DFMCA-LSTM-AE).This unsupervised,end-to-end approach is specifically designed for dynamically monitoring abnormal states in LiB *** method starts with a Dynamic Frequency Fourier Transform module,which dynamically captures the frequency characteristics of time series data across three scales,incorporating a memory mechanism to reduce overgeneralization of abnormal *** is followed by integrating LSTM into both the encoder and decoder,enabling the model to effectively encode and decode the temporal relationships in the time *** tests on a real-world LiB dataset demonstrate that DFMCA-LSTM-AE outperforms existing models,achieving an average Area Under the Curve(AUC)of 90.73%and an F1 score of 83.83%.These results mark significant improvements over existing models,ranging from 2.4%–45.3%for AUC and 1.6%–28.9%for F1 score,showcasing the model’s enhanced accuracy and reliability in detecting abnormal states in LiB data.

关键词： Lithium-ion battery abnormal state detection autoencoder virtual power plants LSTM

Safety-Constrained Multi-Agent Reinforcement Learning for Power Quality Control in Distributed Renewable Energy Networks

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第4期79卷 449-471页

作者： Yongjiang Zhao Haoyi zhong chang Cyoon Lim Department of Computer Engineering Chonnam National UniversityYeosu59626South Korea

This paper examines the difficulties of managing distributed power systems,notably due to the increasing use of renewable energy sources,and focuses on voltage control challenges exacerbated by their variable nature in modern power *** tackle the unique challenges of voltage control in distributed renewable energy networks,researchers are increasingly turning towards multi-agent reinforcement learning(MARL).However,MARL raises safety concerns due to the unpredictability in agent actions during their exploration *** unpredictability can lead to unsafe control *** mitigate these safety concerns in MARL-based voltage control,our study introduces a novel approach:Safety-ConstrainedMulti-Agent Reinforcement Learning(SC-MARL).This approach incorporates a specialized safety constraint module specifically designed for voltage control within the MARL *** module ensures that the MARL agents carry out voltage control actions *** experiments demonstrate that,in the 33-buses,141-buses,and 322-buses power systems,employing SC-MARL for voltage control resulted in a reduction of the Voltage Out of Control Rate(%***)from0.43,0.24,and 2.95 to 0,0.01,and 0.03,***,the Reactive Power Loss(Q loss)decreased from 0.095,0.547,and 0.017 to 0.062,0.452,and 0.016 in the corresponding systems.

关键词： Power quality control multi-agent reinforcement learning safety-constrained MARL

A methodology for laser tool setters calibration and its precise mathematical model

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2024年第7期37卷 564-581页

作者： Tao FANG Zixi FANG Ze zhong CHEN Zhiyong chang School of Mechanical Engineering Northwestern Polytechnical UniversityXi’an 710072China Gina Cody School of Engineering and Computer Science Concordia UniversityMontrealQuebec H3G 1M8Canada changsha Optimum CNC Corporation Changsha 410221China Institute for Aero-engine Smart Assembly of Shaanxi Province Xi’an 710072China

On-machine tool setting is a pivotal approach in achieving intelligent manufacturing,and laser tool setters have become a crucial component of smart machine *** tool setters play a crucial role in precisely measuring the dimensions of cutting tools during the part machining process,focusing on tool length and *** a measuring instrument,the positions of the laser axis of the laser tool setter need to be accurately calibrated before ***,in actual calibration scenarios,traditional calibration methods face challenges due to installation errors in the tool setter and geometric errors in the measuring *** address this issue,this study proposes a novel calibration ***,the calibration mechanism of the laser beam axis is *** on the accurate mathematical model of the laser beam and the measuring rod,and using the polygon clipping algorithm,the mathematical mechanism of the laser tool setter’s work is ***,a novel method is introduced to calculate the compensation distance between the laser beam reference point and the rod bottom center point at each moment during ***,by utilizing the kinematic chain of the tool setter calibration system,a new calibration method is developed to accurately calibrate the position of the laser beam axis in the machine tool coordinate ***,the accuracy of the calibration method is verified through simulation experiments and calibration *** method improves the calibration accuracy of the tool setter,and the mathematical model of the laser tool setter can be extended to the measurement of tools,thereby improving the precision of tool *** research significantly improves the efficient production performance of smart machine tools.

关键词： On-machine tool setting Smart machine tools Mathematical model Calibration method Laser tool sette

Waking Up Brain with Electrical Stimulation to Boost Memory in Sleep:A Neuroscience Exploration

在线全文

学校读者我要写书评

暂无评论

Neuroscience Bulletin 2024年第6期40卷 852-854页

作者： Zhe zhong Fuling yan Chunming Xie Department of Neurology School of MedicineAffiliated Zhongda HospitalSoutheast UniversityNanjing210009China Institute of Neuropsychiatry Affiliated Zhongda HospitalSoutheast UniversityNanjing210009China The Key Laboratory of Developmental Genes and Human Disease Southeast UniversityNanjing210009China

Imagine that,in the future,you could enhance your memory by applying a mild electric current to your brain during *** might sound like science fiction,but it is based on cutting-edge neuroscience *** is widely recognized as a crucial factor for long-term memory consolidation,but the exact mechanisms by which the brain coordinates neural activity across different regions during sleep to reorganize and integrate memories are unknown[1,2].

关键词： Sleep integrate applying

Study of the pressure transient behavior of directional wells considering the effect of non-uniform flux distribution

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Petroleum Science 2024年第3期21卷 1765-1779页

作者： yan-zhong Liang Bai-Lu Teng Wan-Jing Luo School of Energy Resources China University of Geosciences(Beijing)Beijing100083China

During the production,the fluid in the vicinity of the directional well enters the wellbore with different rates,leading to non-uniform flux distribution along the directional ***,in all existing studies,it is oversimplified to a uniform flux distribution,which can result in inaccurate results for field ***,this paper proposes a semi-analytical model of a directional well based on the assumption of non-uniform flux ***,the direction well is discretized into a carefully chosen series of linear sources,such that the complex well trajectory can be captured and the nonuniform flux distribution along the wellbore can be considered to model the three-dimensional flow *** using the finite difference method,we can obtain the numerical solutions of the transient flow within the *** the aid of Green's function method,we can obtain the analytical solutions of the transient flow from the matrix to the *** complete flow behavior of a directional well is perfectly represented by coupling the above two types of transient ***,on the basis of the proposed model,we conduct a comprehensive analysis of the pressure transient behavior of a directional *** computation results show that the flux variation along the direction well has a significant effect on pressure *** addition,the directional well in an infinite reservoir may exhibit the following flow regimes:wellbore afterflow,transition flow,inclined radial flow,elliptical flow,horizontal linear flow,and horizontal radial *** horizontal linear flow can be observed only if the formation thickness is much smaller than the well ***,a dip region that appears on the pressure derivative curve indicates the three-dimensional flow behavior near the wellbore.

关键词： Directional well Pressure transient behavior Semi-analytical model Non-uniform flux