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The effect of fasting plasma glucose on in-hospital mortality after acute myocardial infarction in patients with and without diabetes:findings from a prospective,nationwide,and multicenter registry

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Journal of Geriatric Cardiology 2024年第5期21卷 523-533页

作者： Rui FU Ying-Xuan ZHU Kong-Yong CUI Jin-Gang yanG Hai-yan XU Dong YIN Wei-Hua SONG Hong-Jian WANG Cheng-Gang ZHU Lei FENG Wei WU Kai-HongCHEN yan-yan zhao Ye LU Ke-Fei DOU Yue-Jin yanG on behalf of the CAMI Registry Investigators Cardiometabolic Medicine Center Fuwai HospitalNational Center for Cardiovascular DiseasesState Key Laboratory of Cardiovascular DiseaseNational Clinical Research Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Medical Research&Biometrics Center Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Coronary Heart Disease Center Fuwai HospitalNational Center for Cardiovascular DiseasesState Key Laboratory of Cardiovascular DiseaseNational Clinical Research Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Cardiology Guangzhou Traditional Chinese Medical College First Affiliated HospitalGuangdong ProvinceChina Department of Cardiology Longyan Hospital First HospitalFujian ProvinceChina 不详

OBJECTIVES To evaluate the predictive value of fasting plasma glucose(FPG)for in-hospital mortality in patients with acute myocardial infarction(AMI)with different glucose metabolism *** We selected 5,308 participants with AMI from the prospective,nationwide,multicenter CAMI registry,of which 2,081 were diabetic and 3,227 were *** were divided into high FPG and low FPG groups according to the optim-al cutoff values of FPG to predict in-hospital mortality for diabetic and nondiabetic cohorts,*** primary endpoint was in-hospital *** Overall,94 diabetic patients(4.5%)and 131 nondiabetic patients(4.1%)died during hospitalization,and the optimal FPG thresholds for predicting in-hospital death of the two cohorts were 13.2 mmol/L and 6.4 mmol/L,*** with individuals who had low FPG,those with high FPG were significantly associated with higher in-hospital mortality in diabet-ic cohort(10.1%vs.2.8%;odds ratio[OR]=3.862,95%confidence interval[CI]:2.542-5.869)and nondiabetic cohort(7.4%vs.1.7%;HR=4.542,95%CI:3.041-6.782).After adjusting the potential confounders,this significant association was not ***-more,FPG as a continuous variable was positively associated with in-hospital mortality in single-variable and multivariable models regardless of diabetic *** FPG to the original model showed a significant improvement in C-statistic and net reclassification in diabetic and nondiabetic *** This large-scale registry indicated that there is a strong positive association between FPG and in-hospital mor-tality in AMI patients with and without *** might be useful to stratify patients with AMI.

关键词： patients fasting infarction

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Year aridity index patterns in northwest China and the relationship to summer North Atlantic sea surface temperature

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Acta Oceanologica Sinica 2008年第3期27卷 161-171页

作者： yan yan zhao Xinyi ZHOU Liping College of Urban and Environmental Sciences Laboratory for Earth Surface Processes of Ministry of Education Peking University Beijing 100871 China

Aim to linking the variability of drought in northwest China to the oceanic influence of North Atlantic SSTs at the background of global warming and at the regional climate change shifting stages, year aridity index variations in northwest China and summer North Atlantic sea surface temperature （SST） variations are examined for the 44 a period of 1961-2004 using singular value decomposition （SVD） analysis. Results show that the SST anomalies （SSTA）in the North Atlantic in summer reflected three basic models. The first SVD mode of SST pattern shows a dipole - like variation with the positive center located at southwest and negative center at northeast of extratropical North Atlantic. And it strongly relates to the positive trend in AI variation in northwest China. The second coupled modes display the coherent positive anomalies in extratropical North Atlantic SST and the marked opposite trend of AI variability between north and south of Xinjiang. In addition, the lag correlation analysis of the first mode of SSTA and geopotential heights at 500 hPa variations also shows that the indication of the former influencing the latter configuration, which result in higher air temperature and less precipitation when the SSTA in the North Atlantic Ocean in summer motivated Eurasian circulation of EA pattern, further to influence the wet - dry variations in northwest China by the ocean-to - atmosphere forcing.

关键词： aridity index SSTA teleconnection patterns SVD

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Influence of Y^(3+),Bi^(3+) Content on Photoluminescence of YVO_4∶Dy^(3+) Phosphor Induced by Ultraviolet Excitation

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光谱学与光谱分析 2011年第8期31卷 2053-2057页

作者： HE Yu-yang zhao Mai-qun SONG yan-yan zhao Gao-yang LI Feng The Faculty of Material Science and Engineering Xi＇an University of Technology Xi＇an 710048 China

YxVO4∶0.01Dy3+ and Y0.99-xVO4∶0.01Dy3+,xBi3+ phosphors were synthesized by chemical co-precipitation *** crystal structure,micromorphology and photoluminescence(PL) properties were investigated by X-ray diffraction(XRD),scan electron microscopy(SEM) and ***4∶0.01Dy3+ and Y0.99-xVO4∶0.01Dy3+,xBi3+ phosphors have a broad excitation band from about 250 to 350 nm including a strongest peak at about 310 *** its excitation,the emission spectra exhibits two sharp peaks,one of which centered at about 483 nm for 4F9/2→6H15/2 transition of Dy3+ and the other at about 574 nm due to the 4F9/2→6H13/2 transition of Dy3+.For YxVO4∶0.01Dy3+(x=0.94,0.97,0.99,1.01,1.03) phosphor,with increasing value of x,the body color of phosphor changes from yellow to white and the strongest peak in the excitation spectra shifts a little to shorter *** is detrimental to luminous intensity when Y3+ content deviates stoichiometric *** Y0.99-xVO4∶0.01Dy3+,xBi3+(x=0.01,0.05,0.1,0.15,0.2,0.25) phosphor,the samples have extraneous bismuth vanadium oxide phase except for the major tetragonal zircon structure when x≥*** increasing value of x,the band edge in the excitation spectra shifts to longer wavelength,the excitation intensity and luminous intensity increase early and decrease *** the value of x is 0.01,the intensities increase *** addition,the influence of Y3+ or Bi3+ on the color temperature of emission and micromorphology of YVO4∶Dy3+ is slight.

关键词： YVO4∶Dy3+ Phosphor Body color Photoluminescence Color temperature

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Quantitative estimation of the impact of precipita- tion and human activities on runoff change of the Huangfuchuan River Basin

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Journal of Geographical Sciences 2012年第5期22卷 906-918页

作者： WANG Suiji yan Yunxia yan Ming zhao Xiaokun Key Laboratory of Water Cycle and Related Land Surface Processes Institute of Geographic Sciences andNatural Resources Research CAS Beijing 100101 China

The runoff of some rivers in the world especially in the arid and semi-arid areas has decreased remarkably with global or regional climate change and enhanced human activities. The runoff decrease in the arid and semi-arid areas of northern China has brought severe problems in livelihoods and ecology. To reveal the variation characteristics, trends of runoff and their influencing factors have been important scientific issues for drainage basin man- agement. The objective of this study was to analyze the variation trends of the runoff and quantitatively assess the contributions of precipitation and human activities to the runoff change in the Huangfuchuan River Basin based on the measured data in 1960-2008. Two inflection points （turning years） of 1979 and 1998 for the accumulative runoff change, and one inflection point of 1979 for the accumulative precipitation change were identified using the methods of accumulative anomaly analysis. The linear relationships between year and ac- cumulative runoff in 1960-1979, 1980-1997 and 1998-2008 and between year and accu- mulative precipitation in 1960-1979 and 1980-2008 were fitted. A new method of slope change ratio of accumulative quantity （SCRAQ） was put forward and used in this study to calculate the contributions of different factors to the runoff change. Taking 1960-1979 as the base period, the contribution rate of the precipitation and human activities to the decreased runoff was 36.43% and 63.57% in 1980-1997, and 16.81% and 83.19% in 1998-2008, re- spectively. The results will play an important role in the drainage basin management. More- over, the new method of SCRAQ can be applied in the quantitative evaluation of runoff change and impacts by different factors in the river basin of arid and semi-arid areas.

关键词： runoff precipitation variation trend human activities contribution rate Huangfuchuan River Basin

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ANALYTICAL STUDY ON FLOW PROCESS OF FLOATING-OIL RECOVERY DEVICE FROM OIL-CONTAMINATED SEAWATER BY MHD METHOD

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Journal of Hydrodynamics 2007年第2期19卷 195-200页

作者： ZHANG Guo-yan PENG yan zhao Ling-zhi LI Ran SHA Ci-wen Institute of Electrical Engineering Chinese Academy of Sciences Beijing 100080 China

A new method of recovering maritime oil-spill based on electromagnetic force, the so-called MHD oil-spill recovery method was proposed in the IEECAS. The operating process of MHD channel was described in this article. Numerical study was carried out using a two-dimensional water-air two-phase model and the VOF method. The agreement between the numerical and the experimental results was reached.

关键词： numerical simulation water-air two phaseflow VOF method MHD

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SOX7 is involved in aspirin-mediated growth inhibition of human colorectal cancer cells

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World Journal of Gastroenterology 2011年第44期17卷 4922-4927页

作者： Xin Zhou Shu-yan Huang Jing-Xin Feng yan-yan Gao Li zhao Jun Lu Bai-Qu Huang Yu Zhang The Institute of Genetics and Cytology School of Life Science Northeast Normal University Changchun 130024 Jilin Province China

AIM:To confirm the role of sex-determining region Y-box 7(Sox7) in aspirin-mediated growth inhibition of COX-independent human colorectal cancer ***:The cell survival percentage was examined by MTT(Moto-nuclear cell direc cytotoxicity) ***7 expression was assessed by using reverse transcription-polymerase chain reaction and Western ***203580 was used to inhibit the p38MAPK signal ***7 promoter activity was detected by Luciferase reporter ***:SOX7 was upregulated by aspirin and was involved in aspirin-mediated growth inhibition of SW480 human colorectal cancer *** p38MAPK pathway played a role in aspirin-induced SOX7 expression,during which the AP1 transcription factors c-Jun and c-Fos upregulated SOX7 promoter ***:SOX7 is upregulated by aspirin and is involved in aspirin-mediated growth inhibition of human colorectal cancer SW480 cells.

关键词： SOX7 Aspirin p38MAPK Colorectal cancer SB203580

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UniBind:a novel artificial intelligence-based prediction model for SARS-CoV-2 infectivity and variant evolution

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Signal Transduction and Targeted Therapy 2024年第1期9卷 14-15页

作者： Qihong yan Jincun zhao State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory DiseaseGuangzhou Institute of Respiratory Healththe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhouChina

In a recent study published in Nature Medicine,Wang et *** an excellent framework called UniBind based on artificial intelligence(AI),which enables accurately predicting infectivity of SARS-CoV-2 variants and evolutionary trends of future viral variants.1 This computational method holds the possibility to not only serve as a valuable early-warning tool for monitoring potential pathogenic SARS-CoV-2 variants but also facilitate fundamental research on protein-protein interactions(PPIs).

关键词： artificial Bind prediction

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Effect of electroacupuncture at Sibai on the gastric myoelectric acitivities of denervated rats

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World Journal of Gastroenterology 2006年第36期12卷 5897-5901页

作者： Xiao-Rong Chang Jie yan yan-Ling zhao Jiang-Shang Li Jian-Hua Liu Jun-Feng He College of Acupuncture and Massage Hunan University of Traditional Chinese Medicine Changsha 410007 Hunan Province China

AIM： To explore the mechanism of the exciting effects of electro-acupuncture （EA） at Sibai on the gastric myoelectric activities. METHODS： A total of 32 rats were randomly divided into four groups. Through intraperitoneal injection with atropine （the anti-cholinergic agent by blockade of muscarinic receptors）, hexarnethonium （automatic nerve ganglion-blocking agent） and reserpine （anti-adrenergic agent by depleting the adrenergic nerve terminal of its norepinephrine store）, effects of EA at Sibai on the gastric myoelectric activities of the denervated rats were observed. RESULTS： After intraperitoneal injection of atropine and hexamethonium, the average amplitude and ratio of period to time in the phase of high activity of gastric myoelectric slow wave, and the average numbers of the peaks of gastric myoelectric fast wave were significantly decreased （P 〈 0.01, P 〈 0.05, P 〈 0.01）, while after intraperitoneal injection of reserpine, the aforementioned three parameters were increased （P 〈 0.01, P 〈 0.05, P 〈 0.01）. EA at Sibai point partially relieved the inhibitory effect of atropine and hexamethonium on the gastric myoelectric activities in the rats （P 〈 0.05 or P 〉 0.05）. CONCLUSION： Cholinergic and adrenergic nervous systems and autonomic nerve ganglion participate in the peripheral passage of the controlling effects of EA at Foot yangming Channel on gastrointestinal tract.

关键词： Electro-acupuncture Rats Sibai Nerve block Gastric myoelectric activities

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Research of vitamin E succinate combined with paclitaxel on the apoptosis of Her-2 over-expressing breast cancer cells

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The Chinese-German Journal of Clinical Oncology 2011年第11期10卷 662-665页

作者： Li Li Tingting yan yan zhao Qiuying Jiang Department of Oncology The Second Affiliated Hospital Harbin Medical University Harbin 150086 China

Objective： The aim of this study was to detect apoptosis rates of Her-2 overexpression breast cancer cells, which were administrated with vitamin E succinate （VES） combined with paclitaxel at different dosages, or administrated alone; to discuss the mechanism of their actions. Methods： Using immunohistochemical method to detect Her-2 expression of MDA- MB-453 cells. Using TUNEL assay to detect apoptosis rates of MDA-MB-453 ceils, with the concentrations at 10, 20 mg/L of VES and 50, 100 nmol/L of paclitaxel, and also combined together for 24 or 48 h. Then compared apoptosis action of various combinations. Results： The expression rate of 95% Her-2 was interval （63.32%, 69.60%）; VES and paclitaxel both induced apoptosis of MDA-MB-453 cells, and it is dose to time dependence. It was strongest in apoptosis at 10 mg/L VES and 100 nmol/L paclitaxel in MDA-MB-453 cells 48 h later. Conclusion： VES and paclitaxel both induced apoptosis of MDA-MB-453 cells. It is stronger when the two drugs are administrated together. The mechanism is probably related to reduction of bcl-2 expression, so as to be more sensitive to paclitaxel. Synergistic effect is also possible for the two drugs influence tumor cells in different growing phases.

关键词： vitmian E succinate (VES) paclitaxel breast cancer Her-2 apoptosis

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Proactive Resilience Enhancement of Power Systems with Link Transmission Model-based Dynamic Traffic Assignment Among Electric Vehicles

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CSEE Journal of Power and Energy Systems 2024年第3期10卷 1320-1330页

作者： Haoyuan yan Tianyang zhao Zhanglei Guan Energy Electricity Research Center Jinan UniversityGuangzhou 510632China Energy Research Institute Nanyang Technological UniversitySingapore IEEE

The rapid development of electric vehicles(EVs)is strengthening the bi-directional interactions between electric power networks(EPNs)and transportation networks(TNs)while providing opportunities to enhance the resilience of power systems towards extreme *** quantify the temporal and spatial flexibility of EVs for charging and discharging,a novel dynamic traffic assignment(DTA)problem is *** DTA problem is based on a link transmission model(LTM)with extended charging links,depicting the interaction between EVs and power *** models the charging rates as continuous variables by an energy boundary *** consider the evacuation requirements of TNs and the uncertainties of traffic conditions,the DTA problem is extended to a two-stage distributionally robust *** is further incorporated into a two-stage distributionally robust unit commitment problem to balance the enhancement of EPNs and the performance of *** problem is reformulated into a mixed-integer linear programming problem and solved by off-the-shelf commercial *** studies are performed on two test *** effectiveness is verified by the numerical results,e.g.,reducing the load shedding amount without increasing the unmet traffic demand.

关键词： Coupled transportation and power network link transmission model resilience enhancement

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