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World Journal of Gastroenterology 2024年第9期30卷 1143-1153页

作者： Shan-Shan Wang Meng-Yao Ji Xu Huang yan-xia li Shi-Jie Yu Yu Zhao Lei Shen Department of Gastroenterology Renmin Hospital of Wuhan UniversityWuhan 430000Hubei provinceChina

BACKGROUND Endoscopic full-thickness resection(EFTR)of gastric submucosal tumors(SMTs)is safe and effective;however,postoperative wound management is equally *** on suturing following EFTR for large(≥3 cm)SMTs is scarce and *** To evaluate the efficacy and clinical value of double-nylon purse-string suture in closing postoperative wounds following EFTR of large(≥3 cm)*** We retrospectively analyzed the data of 85 patients with gastric SMTs in the fundus of the stomach or in the lesser curvature of the gastric body whose wounds were treated with double-nylon purse-string sutures after successful tumor resection at the Endoscopy Center of Renmin Hospital of Wuhan *** operative,postoperative,and follow-up conditions of the patients were *** All tumors were completely resected using EFTR.36(42.35%)patients had tumors located in the fundus of the stomach,and 49(57.65%)had tumors located in the body of the *** patients underwent suturing with double-nylon sutures after EFTR without laparoscopic assistance or further surgical *** fever and stomach pain were reported in 13(15.29%)and 14(16.47%)patients,*** serious adverse events occurred during the intraoperative or postoperative periods.A postoperative review of all patients revealed no residual or recurrent *** Double-nylon purse-string sutures can be used to successfully close wounds that cannot be completely closed with a single nylon suture,especially for large(≥3 cm)EFTR wounds in SMTs.

关键词： Endoscopic full-thickness resection Purse-string suture Postoperative wounds Submucosal tumors

Empirical likelihood Method for Quantiles with Response Data Missing at Random

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Acta Mathematicae Applicatae Sinica 2012年第2期28卷 265-274页

作者： xia-yan li Jun-qing YUAN Department of Statistics and Finance University of Science and Technology of China Hefei 230026 China School of Science Zhejiang University of Technology Hangzhou 310023 China

Empirical likelihood is a nonparametric method for constructing confidence intervals and tests, notably in enabling the shape of a confidence region determined by the sample data. This paper presents a new version of the empirical likelihood method for quantiles under kernel regression imputation to adapt missing response data. It eliminates the need to solve nonlinear equations, and it is essy to apply. We also consider exponential empirical likelihood as an alternative method. Numerical results are presented to compare our method with others.

关键词： confidence interval empirical likelihood quantile missing response regression imputation

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Pulmonary Langerhans cell histiocytosis and multiple system involvement:A case report

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World Journal of Clinical Cases 2021年第35期9卷 11029-11035页

作者： lin Luo yan-xia li Department of Critical Care Medicine The Second Hospital of Dalian Medical UniversityDalian 116023Liaoning ProvinceChina Department of Respiratory and Critical Care Medicine Institute of Respiratory DiseasesThe First Affiliated Hospital of Dalian Medical UniversityDalian 116011Liaoning ProvinceChina

BACKGROUND Pulmonary Langerhans cell histiocytosis(PLCH)is a relatively rare type of lung disease,common in middle-aged smoking *** is characterized by proliferation and infiltration of Langerhans cells,and the formation of multiple parabronchial mesenchymal nodules in lung tissue,and may lead to organ *** are no typical symptoms and signs,and it is easily misdiagnosed or missed,and therefore deserves clinical attention and further *** SUMMARY We describe the case of a nonsmoking 46-year-old man with PLCH diagnosed based on clinical manifestations of fever and dry cough,with a history of hypothyroidism and diabetes insipidus for 9 *** tomography(CT)-and CT-guided puncture examinations revealed no abnormalities,and he ultimately underwent thoracoscopic biopsy to confirm the *** pathological diagnosis was *** function was maintained by *** magnetic resonance imaging showed that the pituitary stalk had become *** LCH often involves multiple ***,the pathogenesis is not clear,clinical manifestations lack specificity,and diagnosis requires special *** of PLCH can significantly benefit from comprehensive multidisciplinary analysis.

关键词： Pulmonary Langerhans cell histiocytosis Multiple systems Hypothyroidism Diabetes insipidus Case report

Strong Convergence Theorems of Viscosity Approximation for Accretive Operators

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Journal of Mathematical Research and Exposition 2008年第3期28卷 579-588页

作者： yan li xia ZHOU Hai Yun Department of Mathematics North China Electric Power University Hebei 071003 China

Let E be a real Banach space and let A be an m-accretive operator with a zero. Define a sequence {x_n} as follows:x_n+1=α_nf(x_n)+(1-α_n)J_r_n x_n,where {α_n},{r_n} are sequences satisfying certain conditions,and J_r denotes the resolvent(I+rA)^(-1)for r>*** convergence of the algorithm {x_n} is obtained provided that E either has a weakly continuous duality map or is uniformly smooth.

关键词： fixed point nonexpansive mapping m-accretive operator viscosity approximation weakly continuous duality map uniformly smooth Banach space.

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Two methods of lung biopsy for histological confirmation of acute fibrinous and organizing pneumonia:A case report

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World Journal of Clinical Cases 2022年第36期10卷 13381-13387页

作者： Wen-Juan liu Shuang Zhou yan-xia li Department of Respiratory and Critical Care Medicine Institute of Respiratory DiseasesThe First Affiliated Hospital of Dalian Medical UniversityDalian 116011Liaoning ProvinceChina Department of Internal Medicine Dalian Medical UniversityDalian 116044Liaoning ProvinceChina

BACKGROUND Acute fibrinous and organizing pneumonia(AFOP)is a rare,noninfective lung disease,histologically characterized by a patchy distribution of intra-alveolar fibrin“balls”and organizing *** clinical manifestations of AFOP are *** depends on *** lung biopsy is optimal for tissue sampling to diagnose ***,many patients have no tolerance to the operation,including mentally and *** is still no standard therapy for AFOP and the methods remain ***,further clinical attention and discussion are *** SUMMARY A 53-year-old woman presented with fever,cough and dyspnea for 15 *** therapy was *** computed tomography showed bilateral patchy consolidation,especially in the lower *** performed both ultrasound-guided transbronchial lung biopsy and ultrasound-guided percutaneous fine needle puncture at different lung lesion *** samples supported the diagnosis of *** patient had a good clinical course after treatment with methylprednisolone,and no side effects of *** Percutaneous needle biopsy combined with transbronchial lung biopsies may be a good choice in the absence of surgical *** alone is effective in the treatment of idiopathic AFOP.

关键词： Acute fibrinous and organizing pneumonia Fibrin balls Percutaneous needle biopsy Transbronchial lung biopsies Methylprednisolone Case report

Envafolimab combined with chemotherapy in the treatment of combined small cell lung cancer: A case report

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World Journal of Clinical Cases 2023年第5期11卷 1115-1121页

作者： Mei-Hong liu yan-xia li Zhuo liu Department of Pulmonary and Critical Care Medicine First Affiliated Hospital of Dalian Medical UniversityDalian 116011Liaoning ProvinceChina

BACKGROUND Combined small cell lung cancer(C-SCLC) is a special subtype of small cell lung cancer that is relatively rare, aggressive, and prone to early metastasis and has a poor prognosis. Currently, there are limited studies on C-SCLC, and there is no uniform standard treatment, especially for extensive C-SCLC, which still faces great challenges. In recent years, the development and progress of immunotherapy have provided more possibilities for the treatment of C-SCLC. We used immunotherapy combined with first-line chemotherapy to treat extensive-stage C-SCLC to explore its antitumor activity and *** SUMMARY We report a case of C-SCLC that presented early with adrenal, rib, and mediastinal lymph node metastases. The patient received carboplatin and etoposide with concurrent initiation of envafolimab. After 6 cycles of chemotherapy, the lung lesion was significantly reduced, and the comprehensive efficacy evaluation showed a partial response. No serious drug-related adverse events occurred during the treatment, and the drug regimen was well *** Envafolimab combined with carboplatin and etoposide in the treatment of extensive-stage C-SCLC has preliminary antitumor activity and good safety and tolerability.

关键词： Combined small cell lung cancer Envafolimab Carboplatin Etoposide Prognosis Case report

屈光性弱视及近视高眼压患者视网膜神经纤维层厚度相关性分析

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中国斜视与小儿眼科杂志 2024年第2期32卷 32+55-57页

作者：任璐潘丹闫利霞林有志任艳竹开封市中心医院开封市眼病医院眼科

目的探讨屈光性弱视及近视高眼压患者视网膜神经纤维层厚度相关性分析。方法选取2021年1月至2022年6月收治的50例屈光性弱视患者分为A组、75例近视患者分为B组及30例屈光性弱视合并近视高眼压的患者分为C组。采用Stratus OCT3000成像... 详细信息

目的探讨屈光性弱视及近视高眼压患者视网膜神经纤维层厚度相关性分析。方法选取2021年1月至2022年6月收治的50例屈光性弱视患者分为A组、75例近视患者分为B组及30例屈光性弱视合并近视高眼压的患者分为C组。采用Stratus OCT3000成像仪进行RNFL厚度检测。结果与A组及近视高眼压组比较,C组患者的RNFL厚度更低(P<0.05)。结论屈光性弱视及近视高眼压患者视网膜神经纤维层厚度变薄,并与眼压及黄斑外环区视网膜厚度相关,通过检测指标水平可为疾病的早期诊断提供帮助。

关键词：屈光性弱视近视高眼压视网膜神经纤维层厚度

Paracentral acute middle maculopathy secondary to high intraocular pressure: a case report

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International Journal of Ophthalmology(English edition) 2022年第10期15卷 1723-1725页

作者： Jia li yan-xia li Jing Zhao Ya-Juan Zheng Department of Ophthalmology the Second Hospital of Jilin UniversityJilin UniversityChangchun 130041Jilin ProvinceChina

Dear Editor,Paracentral acute middle maculopathy(PAMM), defined as an optical coherence tomography(OCT) finding characterized by a band-like, hyperreflective lesion at the level of the inner nuclear layer(INL), is the result of impaired flow in the deep and intermediate retinal capillary plexuses[1]. It has been demonstrated that PAMM was related to various retinal vascular disorders, including central retinal vein occlusion。

关键词： capillary finding inner

Vedolizumab-associated diffuse interstitial lung disease in patients with ulcerative colitis:A case report

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World Journal of Clinical Cases 2022年第5期10卷 1716-1722页

作者： Jie Zhang Mei-Hong liu Xue Gao Chang Dong yan-xia li Department of Pulmonary and Critical Care Medicine First Affiliated Hospital of Dalian Medical UniversityDalian 116011Liaoning ProvinceChina Department of Pathology First Affiliated Hospital of Dalian Medical UniversityDalian 116011Liaoning ProvinceChina

BACKGROUND Vedolizumab,a newer class of integrin antagonist biological agents,has been applied to treat patients with moderate-to-severe Crohn’s disease(CD)and ulcerative colitis(UC),especially for patients who are refractory to traditional therapies and tumor necrosis factor ***,some rare but lifethreatening adverse effects warrant *** describe the first fatal case of vedolizumab-associated severe diffuse interstitial lung disease in *** SUMMARY We present a case of new-onset diffuse parenchymal lung disease developing under treatment with vedolizumab in a patient with *** two doses of vedolizumab,he developed persistent fever and progressively worsening *** workups,including bronchoalveolar lavage,transbronchial lung biopsy and metagenomic next-generation sequencing,identified no infectious causes,and other potential causes(such as tumors and cardiogenic pulmonary edema)were also *** a result,a diagnosis of vedolizumabrelated interstitial lung disease was ***,although corticosteroids and empiric antibiotics were administered,the patient eventually died of respiratory *** Vedolizumab-related interstitial lung disease in patients with UC is rare but potentially *** and pulmonologists should be aware of vedolizumab-related adverse drug reactions.

关键词： Vedolizumab Adverse effects Ulcerative colitis Inflammatory bowel disease Interstitial lung disease Case report

Historical records and the sources of polycyclic aromatic hydrocarbons in the East China Sea

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China Geology 2018年第4期1卷 505-511页

作者： xiao-yong Duan yan-xia li xian-guo li Ping Yin Key Laboratory of Marine Hydrocarbon Resources and Environmental Geology Ministry of Land and ResourcesQingdao Institute of Marine GeologyQingdao 266071China Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and TechnologyQingdao 266071China Key Laboratory of Marine Chemistry Theory and Technology Ocean University of ChinaQingdao 266100China Qingdao National Laboratory for Marine Science and Technology Qingdao 266235China

The coastal cities are the most advanced regions in *** the past few decades,the environment changed very significantly due to large scale human activities in the coastal *** aromatic hydrocarbons (PAHs)in three dated sediment cores from the west coast of the Yellow Sea (core A01),the yangtze River estuary (YRE;core A02)and the Oujiang River estuary (ORE;core A03)were analyzed to reconstruct the environmental evolutionary process of the east China coastal region over the past century. In the three cores,PAHs concentrations were increased *** concentrations of PAHs were measured in core A02 than in cores A01 and *** vertical variation of PAHs in the YRE Was dominated by the petrogenic *** records of PAHs in the ORE were controlled by pyrolytic *** on the west coast of the Yellow Sea were contributed by the two sources.

关键词： Polycyclic aromatic hydrocarbons East China Sea Coastal sediment Source Depositional record

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