检索结果-南通市图书馆

Drug-coated balloons for treating de novo lesions in large coronary vessels:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2023年第20期11卷 4920-4925页

作者： Zhi-Qiang Zhang Yi-Ran Qin Man Yin Xue-Heng Chen Lei Chen wen-yan liang Xi-Qing Wei Jining Key Laboratory for Diagnosis and Treatment of Cardiovascular Diseases Jining Medical UniversityAffiliated Hospital of Jining Medical UniversityJining 272000Shandong ProvinceChina Cheeloo College of Medicine Shandong UniversityJinan 250000Shandong ProvinceChina Jining Medical University Affiliated Hospital of Jining Medical UniversityJining 272000Shandong ProvinceChina

BACKGROUND Percutaneous transluminal coronary angioplasty,while an effective intervention,can frequently lead to acute occlusion with severe *** clinical trials have demonstrated the efficacy of drug-coated balloons(DCB)in treating acute coronary artery occlusion and in preventing restenosis,there has been limited exploration on the use of DCB in treating de novo lesions in large ***,DCB are only recommended for patients with small vessel lesions and in-stent restenosis lesions,those at high risk of bleeding,and other special groups of *** SUMMARY This report presents a case of successful drug-coated balloon treatment of de novo lesions in large coronary ***,the patient demonstrated favorable recovery,with subsequent examination results revealing no significant differences from the previous *** The successful treatment of the patient in our case highlights the potential of DCB in the treatment of de novo lesions in large coronary vessels.

关键词： Drug-coated balloons De novo lesions Large coronary vessels Coronary artery disease Percutaneous coronary intervention Case report

Joint Design of ISAC Waveform Under PAPR Constraints

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Communications 2024年第7期21卷 186-211页

作者： Chen Yating wen Cai Huang yan liang Le Li Jie Zhang Hui Hong Wei State Key Lab of Millimeter Waves Southeast UniversityNanjing 211100China School of Information Science and Technology Northwest UniversityXi’an 710127China National Mobile Communications Research Laboratory Nanjing 211100China College of Electronic and Information Engineering Nanjing University of Aeronautics and AstronauticsNanjing 211100China

In this paper,we formulate the precoding problem of integrated sensing and communication(ISAC)waveform as a non-convex quadratically constrained quadratic programming(QCQP),in which the weighted sum of communication multi-user interference(MUI)and the gap between dual-use waveform and ideal radar waveform is minimized with peak-toaverage power ratio(PAPR)*** propose an efficient algorithm based on alternating direction method of multipliers(ADMM),which is able to decouple multiple variables and provide a closed-form solution for each *** addition,to improve the sensing performance in both spatial and temporal domains,we propose a new criteria to design the ideal radar waveform,in which the beam pattern is made similar to the ideal one and the integrated sidelobe level of the ambiguity function in each target direction is minimized in the region of *** limited memory Broyden-Fletcher-Goldfarb-Shanno(LBFGS)algorithm is applied to the design of the ideal radar waveform which works as a reference in the design of the dual-function *** results indicate that the designed dual-function waveform is capable of offering good communication quality of service(QoS)and sensing performance.

关键词： ambiguity function integrated sensing and communication MIMO OFDM PAPR waveform design

Distributed user pairing and effective computation offloading in aerial edge networks

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2024年第4期37卷 378-390页

作者： Wei liang Shuhui wen Lixin LI Jingjing CUI School of Electronics and Information Northwestern Polytechnical UniversityXi’an CN710072China The State Key Laboratory of Integrated Services Networks Xidian UniversityXi’an CN710126China School of Electronics and Computer Science University of SouthamptonSouthampton SO167NSUK

Future Sixth-Generation (6G) mobile communication networks extremely require the global connectivity and the ground Base Stations (BSs) are difficult to develop in some specific areas,such as mountainous ***,the aerial networks are the key framework for the future communications,in which the aerial vehicle could act as the access ***,Mobile Edge Computing (MEC) is also essential to enhance the data processing capabilities of aerial *** this paper,we study a comprehensive communication-computation resource management problem for jointly optimizing user pairing,power and time allocation in the MEC aided Cognitive Radio (CR) aerial networks,namely CR-MEC aerial ***,this multilevel optimization problem could be decomposed into the user pairing and power allocation as well as time allocation *** the conceived CR-MEC aerial networks,we propose a User Pairing and Computation Offloading Management Algorithm (UPCOMA) based on three-sided matching theory,aiming to minimize the system’s energy *** the first step of UPCOMA,multiple Primary Users (PUs) and Cognitive Users (CUs) on the ground negotiate to each other with the suitable power allocation coefficients and construct the stable user ***,the stable user pairs would match to a high altitude platform who act as the base station,which is for appropriately allocating Transmission Time Slots (TSs) at the second step of ***,a hybrid offloading mode is proposed in our conceived networks in order to support ground users to offload their tasks adaptively according to their individual ***,the simulation results reveal that the relative performance of UPCOMA is close to that of the Brute-Force Search Algorithm (BFSA) with low ***,the hybrid offloading mode with less energy consumption supports much more ground user pairs to offload tasks compared to the binary mode.

关键词： Aerial edge computing Binary offloading Cognitive radio Hybrid offloading Resource management

All types of base conversions allowed by base editors

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2024年第2期67卷 431-433页

作者： Shun-Qing liang wen Xue RNA Therapeutics Institute UMass Chan Medical SchoolWorcester 01655USA Department of Molecular Cell and Cancer BiologyUMass Chan Medical SchoolWorcester 01655USA Department of Molecular Medicine UMass Chan Medical SchoolWorcester 01655USA Li Weibo Institute for Rare Diseases Research UMass Chan Medical SchoolWorcester 01655USA

Base editors(BEs) hold great promise as tools for introducing single-base-pair changes in both basic research and therapeutic applications(Rees and Liu,2018).Base editors are composed of a Cas9 nickase fused to a DNA-modifying enzyme,which chemically modifies nucleobases within a specific targeting window near the Cas9-binding site.

关键词： base bases allowed

Extending Structures for Gel'fand-Dorfman Bialgebras

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2024年第2期40卷 619-638页

作者： Jia Jia wen yan Yong HONG School of Mathematics Hangzhou Normal UniversityHangzhou 311121P.R.China

Gel'fand-Dorfman bialgebra,which is both a Lie algebra and a Novikov algebra with some compatibility condition,appeared in the study of Hamiltonian pairs in completely integrable *** also emerged in the description of a class special Lie conformal algebras called quadratic Lie conformal *** this paper,we investigate the extending structures problem for Gel'fand-Dorfman bialgebras,which is equivalent to some extending structures problem of quadratic Lie conformal ***,given a Gel'fand-Dorfman bialgebra(A,o,[.,.]),this problem is how to describe and classify all Gel'fand-Dorfman bialgebra structures on a vector space E(A⊂E)such that(A,o,[.,.])is a subalgebra of E up to an isomorphism whose restriction on A is the identity *** by the theories of extending structures for Lie algebras and Novikov algebras,we construct an object gH2(V,A)to answer the extending structures problem by introducing the notion of a unified product for Gel'fand-Dorfman bialgebras,where V is a complement of A in *** particular,we investigate the special case when dim(V)=1 in detail.

关键词： Gel'fand-Dorfman bialgebra Lie conformal algebra Extending structures problem Novikovalgebra

Resource allocation for D2D-assisted haptic communications

在线全文

学校读者我要写书评

暂无评论

Digital Communications and Networks 2024年第1期10卷 63-74页

作者： yan Wu Chao Yue yang yang liang Ao College of Telecommunication Engineering Army Engineering University of PLANanjing210000China

Haptic communications is recognized as a promising enabler of extensive services by enabling real-time haptic control and feedback in remote environments,e.g.,teleoperation and autonomous *** the strict transmission requirements on reliability and latency,Device-to-Device(D2D)communications is introduced to assist haptic *** particular,the teleoperators with poor channel quality are assisted by auxiliaries,and each auxiliary and its corresponding teleoperator constitute a D2D ***,the haptic interaction and the scarcity of radio resources pose severe challenges to the resource allocation,especially facing the sporadic packet ***,the contentionbased access scheme is applied to achieve low-latency transmission,where the resource scheduling latency is omitted and users can directly access available *** this context,we derive the reliability index of D2D pairs under the contention-based access scheme,i.e.,closed-loop packet error ***,the reliability performance is guaranteed by bidirectional power control,which aims to minimize the sum packet error probability of all D2D *** game theory is introduced to solve the problem with low ***,a distributed power control algorithm based on synchronous log-linear learning is proposed to converge to the optimal Nash *** results demonstrate the superiority of the proposed learning algorithm.

关键词： Haptic communications D2D Power control Contention-based access Potential game

Magnetic Fields Reduce Apoptosis by Suppressing Phase Separation of Tau-441

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research 2024年第1期2023卷 181-197页

作者： wen-Juan Lin wen-Pu Shi Wan-Yi Ge liang-liang Chen Wei-Hong Guo Peng Shang Da-Chuan Yin Key Laboratory for Space Bioscience and Biotechnology School of Life SciencesNorthwestern Polytechnical University127 Youyixi RoadXi'an 710072ShaanxiPR China

The biological effects of magnetic fields(MFs)have been a controversial ***,in recent years,there has been increasing evidence that MFs do affect biological ***,the physical mechanism remains ***,we show that MFs(16 T)reduce apoptosis in cell lines by inhibiting liquid–liquid phase separation(LLPS)of Tau-441,suggesting that the MF effect on LLPS may be one of the mechanisms for understanding the“mysterious”magnetobiological *** LLPS of Tau-441 occurred in the cytoplasm after induction with *** phase-separated droplets of Tau-441 recruited hexokinase(HK),resulting in a decrease in the amount of free HK in the *** cells,HK and Bax compete to bind to the voltage-dependent anion channel(VDAC I)on the mitochondrial membrane.A decrease in the number of free HK molecules increased the chance of Bax binding to VDAC I,leading to increased Bax-mediated *** the presence of a static MF,LLPS was marked inhibited and HK recruitment was reduced,resulting in an increased probability of HK binding to VDAC I and a decreased probability of Bax binding to VDAC I,thus reducing Bax-mediated *** findings revealed a new physical mechanism for understanding magnetobiological effects from the perspective of *** addition,these results show the potential applications of physical environments,such as MFs in this study,in the treatment of LLPS-related diseases.

关键词： inhibited Apoptosis finding

Preparation and characterization of pH-responsive metal-polyphenol structure coated nanoparticles

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2024年第3期13卷 1303-1310页

作者： Qile Xia yan liang Ailing Cao yan Cao Luyun Cai Key Laboratory of Post-Harvest Handling of Fruits Food Science InstituteZhejiang Academy of Agricultural SciencesHangzhou 310021China Ningbo Research Institute College of Biosystems Engineering and Food ScienceZhejiang UniversityNingbo 315100China School of Biological and Chemical Engineering Zhejiang Engineering Research Center for Intelligent Marine Ranch EquipmentNingboTech UniversityNingbo 315100China College of Food Science and Engineering Bohai UniversityJinzhou 121013China Hangzhou Customs District Hangzhou 310007China

In this paper,tannic acid(TA)and Fe~(3+)were added to form a layer of metal-polyphenol network structure on the surface of the nanoparticles which were fabricated by zein and carbon quantum dots(CQDs)encapsulating phlorotannins(PTN).pH-Responsive nanoparticles were prepared successfully(zein-PTN-CQDs-Fe-~Ⅲ).Further,the formation of composite nanoparticles was confirmed by a series of characterization *** zeta-potential and Fourier transform infrared spectroscopy data proved that electrostatic interaction and hydrogen bonding are dominant forces to form *** encapsulation efficiency(EE)revealed that metal-polyphenol network structure could improve the EE of *** analysis and differential scanning calorimetry experiment indicated the thermal stability of zein-PTN-CQDs-Fe~Ⅲnanoparticles increased because of metal-polyphenol network *** pH-responsive nanoparticles greatly increased the release rate of active substances and achieved targeted release.

关键词： Metal Phlorotannins Nanoparticles pH-Responsive Characterization

Effectiveness and tolerability of programmed cell death protein-1 inhibitor+chemotherapy compared to chemotherapy for upper gastrointestinal tract cancers

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2024年第4期16卷 1613-1625页

作者： Xiao-Min Zhang Ting yang Ying-Ying Xu Bao-Zhong Li Wei Shen wen-Qing Hu Cai-wen yan liang Zong Department of Central Laboratory Changzhi People’s HospitalThe Affiliated Hospital of Changzhi Medical CollegeChangzhi 046000Shanxi ProvinceChina Department of Gastrointestinal Surgery Yizheng People’s HospitalThe Affiliated Hospital of Yangzhou UniversityYangzhou 225000Jiangsu ProvinceChina Department of General Surgery Anyang Tumor HospitalAnyang 455000Henan ProvinceChina Department of General Surgery Wuxi People’s Hospital Affiliated to Nanjing Medical UniversityWuxi 214023Jiangsu ProvinceChina Department of Gastrointestinal Surgery Changzhi People’s HospitalThe Affiliated Hospital of Changzhi Medical CollegeChangzhi 046000Shanxi ProvinceChina Department of Gastroenterology Changzhi People’s HospitalThe Affiliated Hospital of Changzhi Medical CollegeChangzhi 046000Shanxi ProvinceChina

BACKGROUND The combination of programmed cell death protein-1(PD-1)inhibitor and che-motherapy is approved as a standard first-or second-line treatment in patients with advanced oesophageal or gastric ***,it is unclear whether this combination is superior to chemotherapy *** To assess the comparative effectiveness and tolerability of combining PD-1 inhibitors with chemotherapy vs chemotherapy alone in patients with advanced gastric cancer,gastroesophageal junction(GEJ)cancer,or oesophageal *** We searched the PubMed and Embase databases for studies that compared the efficacy and tolerance of PD-1 inhibitors in combination with chemotherapy vs chemotherapy alone in patients with advanced oesophageal or gastric *** employed either random or fixed models to analyze the outcomes of each clinical trial,en-compassing data on overall survival(OS),progression-free survival(PFS),objective response rate,and adverse events(AEs).RESULTS Nine phase 3 clinical trials(7016 advanced oesophageal and gastric cancer patients)met the inclusion *** meta-analysis demonstrated that the pooled PD-1 inhibitor+chemotherapy group had a significantly longer OS than the chemotherapy-alone group[hazard ratio(HR)=0.76,95%confidence interval(CI):0.71-0.81];the pooled PFS result was consistent with that of OS(HR=0.67,95%CI:0.61-0.74).The count of patients achieving an objective response in the PD-1 inhibitor+chemotherapy group surpassed that of the chemotherapy-alone group[odds ratio(OR)=1.86,95%CI:1.59-2.18].AE incidence was also higher in the combination-therapy group than in the chemotherapy-alone group,regardless of whether≥grade 3 only(OR=1.30,95%CI:1.07-1.57)or all AE grades(OR=1.88,95%CI:1.39-2.54)were *** performed a subgroup analysis based on the programmed death-ligand 1(PD-L1)combined positive score(CPS)and noted extended OS and PFS durations within the CPS≥1,CPS≥5,and CPS≥10 subgroups of the PD-1 inhibitor+chemotherapy ***

关键词： Programmed cell death protein-1 inhibitor Chemotherapy Oesophageal squamous cell carcinoma Gastric/gastroesophageal junction adenocarcinoma Overall survival Progression-free survival Objective response rate Adverse event