检索结果-南通市图书馆

Comparative Evaluation of Antitumor Chinese Patent Medicine Injections Based on Evidence-Based Medicine and Markov Model

引用

World Journal of Traditional Chinese Medicine 2024年第2期10卷 220-229页

作者： Jing yang yan-peng wang Wen-Gong Yu Yu-Yao Guan Prince Emmanuel Opoku Amponsah Xian-Shuai Tang Ying-Zi Sun Lei Zheng School of Medicine and Pharmacy Ocean University of ChinaQingdaoChina Department of Pharmacy Shandong Medical CollegeJinanChina Department of Pharmacy Cheeloo College of MedicineShandong Provincial Third HospitalShandong UniversityJinanChina Biomedical Engineering Graduate School University of ArizonaTucsonAZUSA

Objective: The objective of this study was to explore the safety, efficacy, economy, and other aspects of frequently-used antitumor Chinese patent medicine injections through a comprehensive evaluation of evidence-based medical research to provide scientific information and decision-making basis for drug selection, rational drug use, public awareness of safe drug use, and medical insurance. Materials and Methods: The names of five frequently used antitumor Chinese patent medicine injections were used as search terms, including the compound Sophora flavescens injection, Kangai injection, Aidi injection, Kanglaite injection, and Brucea javanica oil emulsion injection. Relevant evidence-based medical research was extracted from the databases. A descriptive evaluation was conducted, and the Markov model was used for the cost-benefit analysis. Finally, the above injections are ranked by comprehensive scores using the multi-criteria decision analysis and Delphi method. Results: The five injections had their own advantages in enhancing the effectiveness of anti-tumor treatments, improving the quality of life for cancer patients, and reducing the incidence of adverse reactions. From the perspective of economy and other attributes, compound S. flavescens was superior to B. javanica oil, Aidi, Kangai, and Kanglaite. After a comprehensive evaluation of the above five injections, the compound S. flavescens injection received the highest score. Conclusions: Compound S. flavescens, Kangai, Aidi, B. javanica oil, and Kanglaite have their own advantages in effectiveness and no significant difference in safety. Compound S. flavescens injection has the highest comprehensive score. Clinical attention should be paid to monitoring the initial stage of medication and special groups.

关键词： Anti-tumor Chinese patent medicine comprehensive evaluation medication safety pharmacoeconomics rational drug use

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Hydrogen embrittlement of X80 pipeline steel in H2S environment: Effect of hydrogen charging time, hydrogen-trapped state and hydrogen charging–releasing–recharging cycles

引用

International Journal of Minerals,Metallurgy and Materials 2020年第1期27卷 63-73页

作者： peng-peng Bai Jie Zhou Bing-wei Luo Shu-qi Zheng peng-yan wang Yu Tian State Key Laboratory of Heavy Oil Processing China University of PetroleumBeijing 102249China State Key Laboratory of Tribology Department of Mechanical EngineeringTsinghua UniversityBeijing 100084China JAC Volkswagen Automotive Co. Ltd.Hefei 230601China SINOPEC Tenth Construction Company Ltd.Qingdao 266555China

This study investigated the susceptibility of X80 pipeline steel to hydrogen embrittlement given different hydrogen pre-charging times and hydrogen charging–releasing–recharging cycles in H2S *** fracture strain of the steel samples decreased with increasing hydrogen pre-charging time;this steel degradation could almost be recovered after diffusible hydrogen was removed when the hydrogen pre-charging time was<8 ***,unrecoverable degeneration occurred when the hydrogen pre-charging time extended to 16–30 ***,nanovoid formation meant that the hydrogen damage to the steel under intermittent hydrogen pre-charging–releasing–recharging conditions was more serious than that under continuous hydrogen pre-charging *** study illustrated that the mechanical degradation of steel is inevitable in an H2S environment even if diffusible hydrogen is removed or visible hydrogen-induced cracking is ***,the steel samples showed premature fractures and exhibited a hydrogen fatigue effect because the repeated entry and release of diffusible hydrogen promoted the formation of vacancies that aggregated into *** results provide valuable information on the mechanical degradation of steel in an H2S environment,regarding the change rules of steel mechanical properties under different hydrogen pre-charging times and hydrogen charging–releasing–recharging cycles.

关键词： high-strength steel hydrogen embrittlement corrosion hydrogen diffusion

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of extrusion ratio on the microstructure and texture evolution of AZ31 magnesium alloy by the staggered extrusion(SE)

引用

Journal of Magnesium and Alloys 2020年第4期8卷 1304-1313页

作者： yan-peng wang Feng Li Ye wang Xue-wen Li Wen-win Fang School of Materials Science and Engineering Harbin University of Science and TechnologyNo.4Lin Yuan StreetXiang FangHarbinHeilongjiang 150040China Key Laboratory of Advanced Manufacturing and Intelligent Technology Ministry of EducationHarbin University of Science and TechnologyHarbin 150080China

There are many problems with the conventional processes of magnesium alloy bending products,such as long processes and difficulty in controlling the product *** paper provides a staggered extrusion(SE)process to solve the above manufacturing *** effects of different extrusion ratios(λ)on the AZ31 magnesium alloy bending products prepared by the SE process was investigated in this *** results show that the bending radii of the AZ31 Mg bending products increase with the increase ofλat the same staggered distance(h=16 mm).When A is in creased from 11.11 to 44.44,the average bending radius of bending products is decreased from 14.7 mm to 9 mm,and the average grain size is decreased by 59.43%.After the SE process,the extruded fiber texture of the AZ31 Mg bending products is obvious,and the deformed texture is a mixed texture of{0001}(10-10)deformation texture and{10-11}(11-20)recrystallization *** results of XRD and EBSD showed that pyramidal slip is an important mode of crystal slip systems in AZ31 magnesium alloys during the SE *** provided a scientific basis for forming AZ31 Mg alloy bending products with excellent microstructure by the SE process.

关键词： Magnesium alloy Staggered extrusion(SE) Bending behavior Texture Slip

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Converting LiNO_(3)additive to single nitrogenous component Li_(2)N_(2)O_(2)SEI layer on Li metal anode in carbonate-based electrolyte

引用

Chinese Chemical Letters 2024年第9期35卷 452-457页

作者： Kunyao peng Xianbin wang Xingbin yan Department of Materials Science and Engineering Sun Yat-sen UniversityGuangzhou 510275China State Key Laboratory of Optoelectronic Materials and Technologies Guangzhou 510275China

With the increasing demand for high energy density energy storage device,Li metal has received intensive attention for its ultrahigh capacity and the lowest redox ***_(3)is widely used as electrolyte additive for ether electrolyte,which can improve the cycle performance of Li metal *** to ethers,carbonates are more suitable for Li metal batteries with high voltage cathode because they have a wider electrochemical ***,LiNO_(3)performs poor solubility in carbonate electrolyte,restricting its application in high voltage Li ***,we presented a facile method to introduce abundant LiNO_(3)additive to carbonate electrolyte system by introducing LiNO_(3)-PAN es as the interlayer of the ***_(3)-PAN es is in sufficient contact with the electrolyte so that it can continuously releases LiNO_(3)to assist the formation of Li_(2)N_(2)O_(2)-rich single nitrogenous component SEI layer on Li *** the help of LiNO_(3)-PAN es,Li metal anode shows excellent cycle stability even at a high current density of 4mA/cm^(2),so that the cycle performance of the full cells was significantly improved,whether in the anode-free Cu||LFP cell or the Li||NCM622 cell.

关键词： Li metal anode Electrolyte additive Lithium nitrate Solid electrolyte interphase Carbonate electrolyte

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Numerical Investigation of the Angle of Attack Effect on Cloud Cavitation Flow around a Clark-Y Hydrofoil

引用

Computer Modeling in Engineering & Sciences 2024年第6期139卷 2947-2964页

作者： Di peng Guoqing Chen Jiale yan Shiping wang College of Engineering Peking UniversityBeijing100871China College of Shipbuilding Engineering Harbin Engineering UniversityHarbin150001China

Cavitation is a prevalent phenomenon within the domain of ship and ocean engineering,predominantly occurring in the tail flow fields of high-speed rotating propellers and on the surfaces of high-speed underwater *** re-entrant jet and compression wave resulting from the collapse of cavity vapour are pivotal factors contributing to cavity ***,these phenomena significantly modulate the evolution of cavitation *** this paper,numerical investigations into cloud cavitation over a Clark-Y hydrofoil were conducted,utilizing the Large Eddy Simulation(LES)turbulence model and the Volume of Fluid(VOF)method within the OpenFOAM *** analysis of results obtained at different angles of attack is undertaken.A discernible augmentation in cavity thickness is observed concomitant with the escalation in attack angle,alongside a progressive intensification in pressure at the leading edge of the hydrofoil,contributing to the suction *** results can serve as a fundamental point of reference for gaining a deeper comprehension of cloud cavitation dynamics.

关键词： Cloud cavitation re-entrant jet compression wave clark-Y hydrofoil

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Old canalicular laceration repair:a retrospective study of the curative effects and prognostic factors

引用

International Journal of Ophthalmology(English edition) 2017年第6期10卷 902-907页

作者： Fang Bai Hai Tao yan Zhang peng wang Cui Han Yi-Fei Huang Ye Tao The Lacrimal Center of Ophthalmology Armed Police General Hospital of China Beijing 100039 China

AIM： To investigate the epidemiology and surgical outcomes of old canalicular laceration and analyze the variables impacting on the prognosis of reparation. METHODS： A retrospective review of all old canalicular laceration repairs from Jan. 1, 2008 to Dec. 30, 2015 was performed. Analyzed data included demographics, mechanisms of injury, the time from injury to repair, causes for delayed repair, old associated injuries, the types of surgery, and the effects of repair using canaliculus anastomosis combined with bicanalicular stent intubation. RESULTS： Totally 148 patients with old canalicular laceration received surgical repair and were enrolled. The mean age at presentation was 32.52 years old （ranged from 3 to 63 years old）. The 110 patients （74.32%） were male and 127 patients （85.81%） were adults （__.18 years old）. The old upper, lower, and bicanalicular lacerations were found in 5 （3.38%）, 39 （26.35%）, and 104 patients （70.27%）, respectively. The mechanism of old injury was primarily due to motor vehicle accidents （n=53, 35.81%）. The mean time from injury to repair was 43.61mo （ranged from 1 to 360mo）. Associated old ocular and orbit injuries were found in 65 patients （43.92%）, and chronic dacryocystitis in 18 patients （12.16%）. The main cause of delayed repair was that doctors or patients didn＇t pay attention to the canalicular laceration because of the concurrent severe injuries （n=71, 47.97%）. Totally 136 patients （91.89%） with old canalicular laceration underwent canaliculus anastomosis combined with bicanalicular stent intubation. In all of them, 20 patients （13.51%） were combined with dacryocystorhinostomy. In these cases, 132 patients （97.06%） attained anatomic success, 121 patients （88.97%）reported no epiphora （functional success）, 11 patients （8.09%） reported significant epiphora anesis （functional improvement）, and 4 （2.94%） reported no significant anesis （functional failure）. Rates of anatomic success and functional success were significantly correla

关键词： old canalicular laceration canalicular repair bicanalicular stent

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Thermal and mechanical behavior of casting copper alloy wheel during wheel and belt continuous casting process

引用

China Foundry 2024年第1期21卷 82-90页

作者： Kun Gao yan peng School of Mechanical Engineering Yanshan UniversityQinhuangdao 066004HebeiChina

To investigate the thermal and mechanical behavior of casting wheel,a two-dimensional thermoelastic-plastic finite element model was used to predict the temperature,stress and distortion distribution of the casting wheel during the wheel and belt continuous casting *** effects of grinding thickness and casting speed on the thermal and mechanical behaviors of the center of the hot face of the casting wheel were discussed in *** each rotation,the casting wheel passes through four different spray *** results show that the temperature distribution of the casting wheel in different spray zones is similar,the temperature of the hot face is the highest and the temperature reaches the peak in the spray zoneⅢ.The stress and distortion depend on the temperature distribution,and the maximum stress and distortion of the hot face are 358.2 MPa and 1.82 mm,*** temperature at the center of the hot face decreases with increasing grinding thickness and increases with increasing casting speed.

关键词： casting wheel finite element model grinding thickness casting speed hot face spray zones

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Numerical simulation of fluid flow and free surface fluctuations during wheel and belt casting process

引用

Journal of Iron and Steel Research International 2024年第5期31卷 1117-1126页

作者： Kun Gao yan peng National Engineering Research Center for Equipment and Technology of Cold Strip Rolling Yanshan UniversityQinhuangdao066004HebeiChina

The unstable fluid flow and severe free surface fluctuations in the wheel and belt caster can affect the quality of the cast *** lower level height tends to entrap inclusions in the molten *** the other hand,the higher level height makes the production process more dangerous due to the overflow of high temperature fluid from the mold.A computational model of the molten metal pouring process was *** transient fluid flow and free surface fluctuations behavior were calculated using the three-dimensional large eddy simulation model and the volume of fluid *** results show that the flow velocity of the main jet gradually decreases under the influence of the low kinetic energy fluid in the *** is an obvious oscillation in the tail of the jet,while the flow field is asymmetric in *** jet is closer to the inside radius side due to the Coanda effect,and there is a recirculation zone on the inside radius and the outside radius respectively,according to the 10 s time-averaged *** with the industrial observation and simulation results,the shape of the free surface is a wave that varies with *** addition,the free surface height is lowest and the flow velocity is highest in the region near the jet.

关键词： Fluid flow Free surface Wheel and belt caster Large eddy simulation Volume of fluid method

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oleanolic acid and ursolic acid inhibit proliferation in transformed rat hepatic oval cells

引用

World Journal of Gastroenterology 2014年第5期20卷 1348-1356页

作者： Yu-Ying Han Xiao-Wei Xue Zheng-Ming Shi peng-yan wang Xin-Rui Wu Xue-Jiang wang Department of Medical Genetics Capital Medical University Department of Pathology and Physiology Capital Medical University Department of Surgery Beijing Jishuitan Hospital

AIM: To investigate H2O2-induced promotion proliferation and malignant transformation in WB-F344 cells and anti-tumor effects of ursolic acid (UA) and oleanolic acid (OA).

关键词： Oxidative stress Hepatocarcinogenesis Malignant transformation Oleanolic acid Ursolic acid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Automatic Miscalibration Detection and Correction of LiDAR and Camera Using Motion Cues

引用

Chinese Journal of Mechanical Engineering 2024年第2期37卷 318-329页

作者： Pai peng Dawei Pi Guodong Yin yan wang Liwei Xu Jiwei Feng School of Mechanical Engineering Southeast UniversityNanjing 211102China School of Mechanical Engineering Nanjing University of Science and TechnologyNanjing 210014China School of Mechanical and Aerospace Engineering Nanyang Technological UniversitySingaporeSingapore

This paper aims to develop an automatic miscalibration detection and correction framework to maintain accurate calibration of LiDAR and camera for autonomous vehicle after the sensor ***,a monitoring algorithm that can continuously detect the miscalibration in each frame is designed,leveraging the rotational motion each individual sensor ***,as sensor drift occurs,the projection constraints between visual feature points and LiDAR 3-D points are used to compute the scaled camera motion,which is further utilized to align the drifted LiDAR scan with the camera ***,the proposed method is sufficiently compared with two representative approaches in the online experiments with varying levels of random drift,then the method is further extended to the offline calibration experiment and is demonstrated by a comparison with two existing benchmark methods.

关键词： Autonomous vehicle LiDAR and camera Miscalibration detection and correction Sensor drift

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：