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Identifying key bird species and geographical hotspots of avian influenza A(H7N9)virus in China

Infectious Diseases of Poverty 2018年第1期7卷 1019-1029页

作者： Benyun Shi Xiao-ming Zhan Jin-Xin Zheng Hongjun Qiu Dan Liang yan-ming ye Guo-Jing yang yang Liu Jiming Liu School of Cyberspace Hangzhou Dianzi UniversityHangzhou 310018People’s Republic of China School of Computer Science and Technology Hangzhou Dianzi UniversityHangzhou 310018People’s Republic of China Jiangsu Institute of Parasitic Diseases Wuxi 214064People’s Republic of China Department of Epidemiology and Public Healthy Swiss Tropical and Public Health InstituteBaselSwitzerland University of Basel BaselSwitzerland State Key Laboratory of Biocontrol Department of Ecology and School of Life SciencesSun Yat-Sen UniversityGuangzhou 510275People’s Republic of China Department of Computer Science Hong Kong Baptist UniversityKowloon TongHong KongPeople’s Republic of China

Background:In China since the first human infection of avian influenza A(H7N9)virus was identified in 2013,it has caused serious public health concerns due to its wide spread and high mortality *** shows that bird migration plays an essential role in global spread of avian influenza ***,in this paper,we aim to identify key bird species and geographical hotspots that are relevant to the transmission of avian influenza A(H7N9)virus in ***:We first conducted phylogenetic analysis on 626 viral sequences of avian influenza A(H7N9)virus isolated in chicken,which were collected from the Global Initiative on Sharing All Influenza Data(GISAID),to reveal geographical spread and molecular evolution of the virus in ***,we adopted the cross correlation function(CCF)to explore the relationship between the identified influenza A(H7N9)cases and the spatiotemporal distribution of migratory ***,the spatiotemporal distribution of bird species was generated based on bird observation data collected from China Bird Reports,which consists of 157272 observation records about 1145 bird ***,we employed a kernel density estimator to identify geographical hotspots of bird habitat/stopover that are relevant to the influenza A(H7N9)***:Phylogenetic analysis reveals the evolutionary and geographical patterns of influenza A(H7N9)infections,where cases in the same or nearby municipality/provinces are clustered together with small evolutionary ***,three epidemic waves in chicken along the East Asian-Australasian flyway in China are distinguished from the phylogenetic *** CCF analysis identifies possible migratory bird species that are relevant to the influenza A(H7N9)infections in Shanghai,Jiangsu,Zhejiang,Fujian,Jiangxi,and Guangdong in China,where the six municipality/provinces account for 91.2%of the total number of isolated H7N9 cases in chicken in *** on the spatial distribution of identi

关键词： Avian influenza virus Bird migration Geographical hotspots Phylogenetic analysis Cross correlation function

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用于眼科学的新型激光装置

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激光与红外 1986年第6期 49-51页

作者： yan-ming ye

激光装置的结构与性能装置根据以下考虑设计:1)当用于多种眼病疗法所需较低脉冲能量时,最好具有短脉冲激光;2)用于视觉治疗的激光波长是在450～600nm附近;3)为了治疗安全起见,必需防止任何不正常的激光触发脉冲。为了满足这些要求,设计... 详细信息

激光装置的结构与性能装置根据以下考虑设计:1)当用于多种眼病疗法所需较低脉冲能量时,最好具有短脉冲激光;2)用于视觉治疗的激光波长是在450～600nm附近;3)为了治疗安全起见,必需防止任何不正常的激光触发脉冲。为了满足这些要求,设计了一种组合装置,把由闪光灯泵浦以590nm波长工作的染料激光器与光耦合系统及电路系统组合起来

关键词：虹膜切开术外科闪光灯泵浦虹膜基质染料激光器液体激光器

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MoS_(2)Lubricate‑Toughened MXene/ANF Composites for Multifunctional Electromagnetic Interference Shielding

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Nano-Micro Letters 2025年第2期17卷 358-371页

作者： Jiaen Wang Wei ming Longfu Chen Tianliang Song Moxi yele Hao Zhang Long yang Gegen Sarula Benliang Liang Luting yan Guangsheng Wang School of Physical Science and Engineering Beijing Jiaotong UniversityBeijing 100044People’s Republic of China Key Laboratory of Bio‑Inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191People’s Republic of China

The design and fabrication of high toughness electromagnetic interference(EMI)shielding composite films with diminished reflection are an imperative task to solve electromagnetic pollution *** MXene/ANF(aramid nanofibers)–MoS_(2)composite films with nacre-like layered structure here are fabricated after the introduction of MoS_(2)into binary MXene/ANF composite *** introduction of MoS_(2)fulfills an impressive“kill three birds with one stone”improvement effect:lubrication toughening mechanical performance,reduction in secondary reflection pollution of electromagnetic wave,and improvement in the performance of photothermal *** the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 50:50),the strain to failure and tensile strength increase from 22.1±1.7%and 105.7±6.4 MPa and to 25.8±0.7%and 167.3±9.1 MPa,*** toughness elevates from 13.0±4.1 to 26.3±0.8 MJ m^(−3)(~102.3%)*** the reflection shielding effectiveness(SE_(R))of MXene/ANF(mass ratio of 50:50)decreases~10.8%.EMI shielding effectiveness(EMI SE)elevates to 41.0 dB(8.2–12.4 GHz);After the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 60:40),the strain to failure increases from 18.3±1.9%to 28.1±0.7%(~53.5%),the SE_(R)decreases~22.2%,and the corresponding EMI SE is 43.9 *** MoS_(2)also leads to a more efficient photothermal conversion performance(~45 to~55℃).Additionally,MXene/ANF–MoS_(2)composite films exhibit excellent electric heating performance,quick temperature elevation(15 s),excellent cycle stability(2,2.5,and 3 V),and long-term stability(2520 s).Combining with excellent mechanical performance with high MXene content,electric heating performance,and photothermal conversion performance,EMI shielding ternary MXene/ANF–MoS_(2)composite films could be applied in many industrial *** work broadens how to achieve a balance between mechanical properties and versatility of composites in the case of high-function fillers.

关键词： MXene-MoS_(2) Lubrication toughening EMI shielding Photothermal conversion Electric heating performance

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聚(左旋乳酸-己内酯)/明胶静电纺丝支架对大鼠骨髓来源内皮祖细胞成血管分化的影响

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上海交通大学学报（医学版） 2018年第5期38卷 499-504页

作者：张夏郑雷蕾刘艳明叶何昊珏胡赟重庆医科大学附属口腔医院口腔疾病与生物医学重庆市重点实验室重庆市高校市级口腔生物医学工程重点实验室重庆401147

目的·探讨聚(左旋乳酸-己内酯)[poly(L-lactic acid caprolactone),PLCL]/明胶静电纺丝支架对内皮祖细胞(endothelial progenitor cells,EPCs)成血管分化的影响。方法·分离大鼠EPCs后进行培养、鉴定。制作PLCL/明胶静电纺丝支架,进行... 详细信息

目的·探讨聚(左旋乳酸-己内酯)[poly(L-lactic acid caprolactone),PLCL]/明胶静电纺丝支架对内皮祖细胞(endothelial progenitor cells,EPCs)成血管分化的影响。方法·分离大鼠EPCs后进行培养、鉴定。制作PLCL/明胶静电纺丝支架,进行扫描电子显微镜及水接触角测试。EPCs种植于PLCL/明胶静电纺丝支架上,CCK8法检测细胞增殖。采用RT-PCR检测成血管相关基因血管内皮生长因子(vascular endothelial growth factor,Vegf)、激酶插入区受体(kinases insert region receptor,Kdr)表达,Western blotting技术检测VEGF蛋白表达。结果·密度梯度离心配合差速贴壁法可有效分离EPCs,PLCL/明胶静电纺丝纳米纤维高密度多孔,亲水性能有利于细胞黏附,EPCs在支架上生长良好。PLCL/明胶组Vegf及Kdr基因的表达较对照组显著增加(P=0.000),VEGF蛋白表达也显著增强(P=0.000)。结论·PLCL/明胶是组织工程理想支架,且对EPCs成血管分化有促进作用。

关键词：聚(左旋乳酸-己内酯) 内皮祖细胞分离培养生物学鉴定静电纺丝成血管

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Risk analysis of gastrointestinal bleeding in hospital patients with acute myocardial infarction undergoing primary PCI

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Journal of Geriatric Cardiology 2023年第5期20卷 386-390页

作者： yan-yan JIN ming ye Hai GAO Center for Coronary Artery Disease Division of CardiologyBeijing Anzhen HospitalCapital Medical UniversityBeijingChina

Dual antiplatelet therapy with aspirin and a P2Y12 inhibitor is the cornerstone of acute myocardial infarction(AMI)management,both invasive and conservative.[1,2]This dual strategy improved ischemic outcomes but was offset by an increased bleeding *** prognostic importance of bleeding events has been well established over the past decades,as several studies have shown a strong association between bleeding and mortality.[3]The CRUSADE score is superior to other scores in predicting in-hospital major bleeding *** this regard,in its non-ST elevation acute coronary syndromes(NSTE-ACS)guidelines,the European Society of Cardiology(ESC)stated that the CRUSADE score could be considered for bleeding risk quantification of coronary angiography in NSTE-ACS patients(class IIb,level B evidence).[4]However,the most common site of spontaneous.

关键词： bleeding acute patients

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Mediating role of health literacy in the relationship between social isolation and psychological distress among pre-frail older adults

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World Journal of Psychiatry 2025年第1期15卷 137-144页

作者： Juan Fang Li-Hui Li ming-Qian He Yue Ji Dong-yan Lu Li-Bing Zhang Jin-Lan Yao School of Medicine Huzhou UniversityHuzhou 313000Zhejiang ProvinceChina

BACKGROUND Frailty has become a significant public health *** recent increase in the number of frail older adults has led to increased attention being paid to psycho-logical care services in *** social isolation of pre-frail older adults can impact their psychological *** To explore the mediating effect of health literacy between social isolation and psychological distress among communitydwelling older adults with *** This descriptive cross-sectional study was conducted with 254 pre-frail older individuals aged 60 years and *** isolation,health literacy,and psycholo-gical distress were comprehensively measured using the Lubben Social Network Scale-6,12-item Short-Form Health Literacy Questionnaire,and the Kessler Psy-chological Distress *** were evaluated using the SPSS 27.0 package program and the PROCESS macro *** statistical analyses,correlation analyses,and bootstrap mediation tests were used to assess associations between the *** The results showed that social isolation had an effect on health literacy among pre-frail older adults(β=0.240,P<0.001),social isolation impact on psycho-logical distress pre-frail older adults(β=-0.415,P<0.001);health literacy was identified effect on psychological distress among pre-frail older persons(β=-0.307,P<0.001).Health literacy partially mediated the relationship between social isolation and psychological distress among community-dwelling older adults with pre-frailty,with a mediation effect of-0.074,accounting for 17.83%of the total effect.

关键词： Frail Ageing Psychological distress Health literacy Social isolation

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Color Image Super-Resolution and Enhancement with Inter-Channel Details at Trivial Cost

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Journal of Computer Science & Technology 2020年第4期35卷 889-899页

作者： Chuang-ye Zhang yan Niu Tie-Ru Wu Xi-ming Li College of Computer Science and Technology Jilin UniversityChangchun 130012China Key Laboratory of Symbolic Computer and Knowledge Engineering of Ministry of Education Jilin University Changchun 130012China School of Mathematics Jilin UniversityChangchun 130012China

Image super-resolution is essential for a variety of applications such as medical imaging,surveillance imaging,and satellite imaging,among ***,the most popular color image super-resolution is performed in each color channel *** this paper,we show that the super-resolution quality can be further enhanced by exploiting the cross-channel *** by the High-Quality Linear Interpolation(HQLI)demosaicking algorithm by Malvar et al.,we design an image super-resolution scheme that integrates intra-channel interpolation with cross-channel details by isotropic linear *** its simplicity,our super-resolution method achieves the accuracy comparable with the existing fastest state-of-the-art super-resolution algorithm at 20 times faster *** is well applicable to applications that adopt traditional interpolations,for improved visual quality at trivial computation *** comparative study verifies the effectiveness and efficiency of the proposed super-resolution algorithm.

关键词： image super-resolution isotropic linear interpolation inter-channel detail enhancement low cost

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Chondroitinase ABC combined with Schwann cell transplantation enhances restoration of neural connection and functional recovery following acute and chronic spinal cord injury

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Neural Regeneration Research 2025年第5期20卷 1467-1482页

作者： Wenrui Qu Xiangbing Wu Wei Wu Ying Wang yan Sun Lingxiao Deng Melissa Walker Chen Chen Heqiao Dai Qi Han Ying Ding Yongzhi Xia George Smith Rui Li Nai-Kui Liu Xiao-ming Xu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteDepartment of Neurological SurgeryIndiana University School of MedicineIndianapolisINUSA Department of Hand Surgery the Second Hospital of Jilin UniversityChangchunJilin ProvinceChina Shriners Hospitals Pediatric Research Center Temple University School of MedicinePhiladelphiaPAUSA Department of Anatomy&Cell Biology Indiana University School of MedicineIndianapolisINUSA

Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties.A the Food and Drug Administration-approved Phase I clinical trial has been conducted to evaluate the safety of transplanted human autologous Schwann cells to treat patients with spinal cord injury.A major challenge for Schwann cell transplantation is that grafted Schwann cells are confined within the lesion cavity,and they do not migrate into the host environment due to the inhibitory barrier formed by injury-induced glial scar,thus limiting axonal reentry into the host spinal *** we introduce a combinatorial strategy by suppressing the inhibitory extracellular environment with injection of lentivirus-mediated transfection of chondroitinase ABC gene at the rostral and caudal borders of the lesion site and simultaneously leveraging the repair capacity of transplanted Schwann cells in adult rats following a mid-thoracic contusive spinal cord *** report that when the glial scar was degraded by chondroitinase ABC at the rostral and caudal lesion borders,Schwann cells migrated for considerable distances in both rostral and caudal *** Schwann cell migration led to enhanced axonal regrowth,including the serotonergic and dopaminergic axons originating from supraspinal regions,and promoted recovery of locomotor and urinary bladder ***,the Schwann cell survival and axonal regrowth persisted up to 6 months after the injury,even when treatment was delayed for 3 months to mimic chronic spinal cord *** findings collectively show promising evidence for a combinatorial strategy with chondroitinase ABC and Schwann cells in promoting remodeling and recovery of function following spinal cord injury.

关键词： axonal regrowth bladder function chondroitinase ABC functional recovery glial scar lentivirus migration Schwann cell spinal cord injury transplantation

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Scene text removal via cascaded text stroke detection and erasing

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Computational Visual Media 2022年第2期8卷 273-287页

作者： Xuewei Bian Chaoqun Wang Weize Quan Juntao ye Xiaopeng Zhang Dong-ming yan National Laboratory of Pattern Recognition Institute of AutomationBeijing 100049China School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100084China

Recent learning-based approaches show promising performance improvement for the scene text removal task but usually leave several remnants of text and provide visually unpleasant *** this work,a novel end-to-end framework is proposed based on accurate text stroke ***,the text removal problem is decoupled into text stroke detection and stroke removal;we design separate networks to solve these two subproblems,the latter being a generative *** two networks are combined as a processing unit,which is cascaded to obtain our final model for text *** results demonstrate that the proposed method substantially outperforms the state-of-the-art for locating and erasing scene text.A new large-scale real-world dataset with 12,120 images has been constructed and is being made available to facilitate research,as current publicly available datasets are mainly synthetic so cannot properly measure the performance of different methods.

关键词： scene text removal text stroke detection generative adversarial networks cascaded network design real-world dataset

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Effects of Prior Corrosion with and Without Stress on the Mechanical Properties of 7475-T761 Aluminum Alloy

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Acta Metallurgica Sinica(English Letters) 2015年第5期28卷 608-613页

作者： Zuo-yan ye Dao-Xin Liu Meng Yuan Xiao-ming Zhang Zhi yang ming-Xia Lei Corrosion and Protection Research Laboratory Northwestern Polytechnical University Aviation Industry Corporation of China the First Aircraft Institute

The effect of prior corrosion on the mechanical properties of 7475-T761 aluminum alloy was investigated by immersion test, stress corrosion test, cathode charge method and electrochemical polarization test. Results show that prior corrosion in the solution with 3 wt% NaC1 and 0.5 wt% H202 leads to mechanical properties deterioration of 7475-T761 aluminum alloy. Moreover, the elongation decreases significantly. This is mainly attributed to electrochemical corrosion and hydrogen embrittlement, in which corrosion plays a major role. Tensile stress promotes the degradation of the mechanical properties by accelerating the pitting corrosion and hydrogen embrittlement.

关键词： Prior corrosion Corrosion with stress 7475 aluminum alloy Mechanical properties Hydrogen embrittlement

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