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Journal of Geriatric Cardiology 2024年第1期21卷 34-43页

作者： Yong-Gang SUI Cheng yanG Chang-Dong GUAN yan-lu xu Na-Qiong WU Wei-Xian yanG Yong-Jian WU Ke-Fei DOU Yue-Jin yanG Shu-Bin QIAO Wei YU Bo xu Sheng-Xian TU Jie QIAN Department of Cardiology Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Catheterization Laboratories Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Biomedical Instrument Institute School of Biomedical EngineeringShanghai Jiao Tong UniversityShanghaiChina National Clinical Research Center for Cardiovascular Diseases BeijingChina

BACKGROUND The recently introduced ultrasonic flow ratio(UFR),is a novel fast computational method to derive fractional flow reserve(FFR)from intravascular ultrasound(IVUS)*** the present study,we evaluate the diagnostic performance of UFR in patients with intermediate left main(LM)*** This is a prospective,single center study enrolling consecutive patients with presence of intermediated LM lesions(diameter stenosis of 30%-80%by visual estimation)underwent IVUS and FFR *** independent core laboratory assessed offline UFR and IVUS-derived minimal lumen area(MLA)in a blinded *** Both UFR and FFR were successfully achieved in 41 LM patients(mean age,62.0±9.9 years,46.3%diabetes).An acceptable correlation between UFR and FFR was identified(r=0.688,Plute numerical difference of 0.03(standard difference:0.01).The area under the curve(AUC)in diagnosis of physiologically significant coronary stenosis for UFR was 0.94(95%CI:0.87-1.01),which was significantly higher than angiographic identified stenosis>50%(AUC=0.66,Pluation of intermediate LM stenosis.

关键词： stenosis flow fractional

Random gradient-free method for online distributed optimization with strongly pseudoconvex cost functions

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Control Theory and Technology 2024年第1期22卷 14-24页

作者： Xiaoxi yan Cheng Li Kaihong lu Hang xu School of Electrical and Information Engineering Jiangsu UniversityZhenjiang212013JiangsuChina College of Electrical Engineering and Automation Shandong University of Science and TechnologyQingdao266590ShandongChina

This paper focuses on the online distributed optimization problem based on multi-agent systems. In this problem, each agent can only access its own cost function and a convex set, and can only exchange local state information with its current neighbors through a time-varying digraph. In addition, the agents do not have access to the information about the current cost functions until decisions are made. Different from most existing works on online distributed optimization, here we consider the case where the cost functions are strongly pseudoconvex and real gradients of the cost functions are not available. To handle this problem, a random gradient-free online distributed algorithm involving the multi-point gradient estimator is proposed. Of particular interest is that under the proposed algorithm, each agent only uses the estimation information of gradients instead of the real gradient information to make decisions. The dynamic regret is employed to measure the proposed algorithm. We prove that if the cumulative deviation of the minimizer sequence grows within a certain rate, then the expectation of dynamic regret increases sublinearly. Finally, a simulation example is given to corroborate the validity of our results.

关键词： Multi-agent system Online distributed optimization Pseudoconvex optimization Random gradient-free method

Metasurface-based computational imaging:a review

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Advanced Photonics 2024年第1期6卷 43-63页

作者： xuemei Hu Weizhu xu Qingbin Fan Tao Yue Feng yan yanqing lu Ting xu Nanjing University Collaborative Innovation Center of Advanced MicrostructuresNational Laboratory of Solid-State MicrostructuresNanjingChina Nanjing University School of Electronic Sciences and EngineeringNanjingChina Nanjing University College of Engineering and Applied SciencesJiangsu Key Laboratory of Artificial Functional MaterialsNanjingChina

Metasurface-based imaging has attracted considerable attention owing to its compactness,multifunctionality,and subwavelength coding *** the integration of computational imaging techniques,researchers have actively explored the extended capabilities of metasurfaces,enabling a wide range of imaging *** present an overview of the recent progress in metasurface-based imaging techniques,focusing on the perspective of computational ***,we categorize and review existing metasurface-based imaging into three main groups,including(i)conventional metasurface design employing canonical methods,(ii)computation introduced independently in either the imaging process or postprocessing,and(iii)an end-to-end computation-optimized imaging system based upon *** highlight the advantages and challenges associated with each computational metasurface-based imaging technique and discuss the potential and future prospects of the computational boosted metaimager.

关键词： metasurface computational imaging inverse problem algorithm

Reducing Subspaces of Toeplitz Operators Induced by a Class of Non-analytic Monomials over the Unit Ball

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Acta Mathematica Sinica,English Series 2024年第7期40卷 1767-1777页

作者： yan Yue SHI Bo ZHANG xu TANG Yu Feng lu School of Mathematical Sciences Ocean University of ChinaQingdao 266100P.R.China School of Mathematics and Information Sciences Yantai UniversityYantai 264005P.R.China School of Mathematical Sciences Space Engineering UniversityBeijing 101416P.R.China School of Mathematical Sciences Dalian University of TechnologyDalian 116024P.R.China

In this paper,we describe the minimal reducing subspaces of Toeplitz operators induced by non-analytic monomials on the weighted Bergman spaces and Dirichlet spaces over the unit ball B_(2).It is proved that each minimal reducing subspace M is finite dimensional,and if dim M≥3,then M is induced by a ***,the structure of commutant algebra v(T_(w)N_(z)N):={M^(*)_(w)NM_(z)N,M^(*)_(z)NM_(w)N}′is determined by N and the two dimensional minimal reducing subspaces of(T_(w)N_(z)*** also give some interesting examples.

关键词： Reducing subspace operator-weighted shifts Toeplitz operator von Neumann algebra

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Tailoring electron vortex beams with customizable intensity patterns by electron diffraction holography

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Opto-Electronic Advances 2024年第2期7卷 14-21页

作者： Pengcheng Huo Ruixuan Yu Mingze Liu Hui Zhang yan-qing lu Ting xu National Laboratory of Solid-State Microstructures and Collaborative Innovation Center of Advanced Microstructures Nanjing UniversityNanjing 210093China College of Engineering and Applied Sciences Key Laboratory of Intelligent Optical Sensing and Manipulation and Jiangsu Key Laboratory of Artificial Functional MaterialsNanjing UniversityNanjing 210093China

An electron vortex beam(EVB) carrying orbital angular momentum(OAM) plays a key role in a series of fundamental scientific researches, such as chiral energy-loss spectroscopy and magnetic dichroism spectroscopy. So far, almost all the experimentally created EVBs manifest isotropic doughnut intensity patterns. Here, based on the correlation between local divergence angle of electron beam and phase gradient along azimuthal direction, we show that free electrons can be tailored to EVBs with customizable intensity patterns independent of the carried OAM. As proof-of-concept, by using computer generated hologram and designing phase masks to shape the incident free electrons in the transmission electron microscope, three structured EVBs carrying identical OAM are tailored to exhibit completely different intensity patterns. Furthermore, through the modal decomposition, we quantitatively investigate their OAM spectral distributions and reveal that structured EVBs present a superposition of a series of different eigenstates induced by the locally varied geometries. These results not only generalize the concept of EVB, but also demonstrate an extra highly controllable degree of freedom for electron beam manipulation in addition to OAM.

关键词： electron vortex beam orbital angular momentum diffraction holography

Identifying the geographical origin and processing technology of Moyao(Myrrh) on the basis of near-infrared spectroscopy combined with chemometrics

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Journal of Traditional Chinese Medicine 2024年第3期44卷 505-514页

作者： xu Ningning yan Ganming xu Fengjie DENG Linfeng QIAO Xinjiang lu Changzheng CHENG Shaomin TCM Diagnosis Institute College of Traditional Chinese MedicineJiangxi University of Chinese Medicine TCM Processing Institute Pharmaceutical CollegeJiangxi University of Chinese medicine School of Electronic Information and Artificial Intelligence Shaanxi University of Science and Technology Jiangzhong Pharmaceutical Co. Ltd. Jiangxi Guhan Refined Chinese Herbal Pieces Co. Ltd.

OBJECTIVE: To evaluate the quality of Moyao(Myrrh) in the identification of the geographical origin and processing of the products. METHODS: Raw Moyao(Myrrh) and two kinds of Moyao(Myrrh) processed with vinegar from three countries were identified using near-infrared(NIR) spectroscopy combined with chemometric techniques. Principal component analysis(PCA) was used to reduce the dimensionality of the data and visualize the clustering of samples from different categories. A classical chemometric algorithm(PLS-DA) and two machine learning algorithms [K-nearest neighbor(KNN) and support vector machine] were used to conduct a classification analysis of the near-infrared spectra of the Moyao(Myrrh) samples, and their discriminative performance was evaluated. RESULTS: Based on the accuracy, precision, recall rate, and F1 value in each model, the results showed that the classical chemometric algorithm and the machine learning algorithm obtained positive results. In all of the chemometric analyses, the NIR spectrum of Moyao(Myrrh) preprocessed by standard normal variation or Multivariate scattering correction combined with KNN achieved the highest accuracy in identifying the geographical origins, and the accuracy of identifying the processing technology established by the KNN method after first-order derivative pretreatment was the best. The best accuracy of geographical origin discrimination and processing technology discrimination were 0.9853 and 0.9706 respectively. CONCluSIONS: NIR spectroscopy combined with chemometric technology can be an important tool for tracking the origin and processing technology of Moyao(Myrrh) and can also provide a reference for evaluations of its quality and the clinical use.

关键词： Moyao () geographical origin near-infrared spectroscopy processing technology

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Application of organic manure as a potential strategy to alleviate the limitation of microbial resources in soybean rhizospheric and bulk soils

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Journal of Integrative Agriculture 2024年第6期23卷 2065-2082页

作者： Zhimin Wu Xiaozeng Han xu Chen Xinchun lu Jun yan Wei Wang Wenxiu Zou Lei yan School of Resources and Environment Northeast Agricultural UniversityHarbin 150030China Key Laboratory of Mollisols Agroecology Northeast Institute of Geography and AgroecologyChinese Academy of SciencesHarbin 150081China Heilongjiang Academy of Agricultural Sciences Harbin 150086China

The development and vigor of soil microorganisms in terrestrial ecosystems are frequently constrained by the limited availability of essential elements such as carbon(C),nitrogen(N),and phosphorus(P).In this study,we investigated the impact of long-term application of varying levels of organic manure,low(7.5 Mg ha^(−1)yr^(−1)),moderate(15.0 Mg ha^(−1)yr^(−1)),and high(22.5 Mg ha^(−1)yr^(−1)),on the stoichiometry of enzymes and the structures of the microbial communities in soybean rhizospheric and bulk *** main goal of this research was to examine how soil microbial resource limitations in the rhizosphere respond to different long-term fertilization *** soil enzymatic activities were quantified,and the structure of the microbial community was assessed by analyzing phospholipid fatty acid *** compared to the bulk soil,the rhizospheric soil had significant increases in microbial biomass carbon(MBC),nitrogen(MBN),and phosphorus(MBP),with MBC increasing by 54.19 to 72.86%,MBN by 47.30 to 48.17%,and MBP by 17.37 to 208.47%.Compared with the unfertilized control(CK),the total microbial biomasses of the rhizospheric(increased by 22.80 to 90.82%)and bulk soils(increased by 10.57 to 60.54%)both exhibited increases with the application of organic manure,and the rhizospheric biomass was higher than that of bulk *** with bulk soil,the activities of C-,N-and P-acquiring enzymes of rhizospheric soil increased by 22.49,14.88,and 29.45%under high levels of organic manure,*** of vector length,vector angle,and scatter plots revealed that both rhizospheric and bulk soils exhibited limitations in terms of both carbon(C)and phosphorus(P)*** results of partial least-squares path modelling indicated that the rhizospheric soil exhibited a more pronounced response to the rate of manure application than the bulk *** varying reactions of rhizospheric and bulk soils to the extended application of organic manure underscore

关键词： enzymatic stoichiometry rhizosphere phospholipid fatty acids soybean organic manure

Insights into the kinetics–morphology relationship of 1-, 2-, and 3D TiNb_(2)O_(7) anodes for Li-ion storage

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Nano Research 2024年第4期17卷 2770-2780页

作者： Wenlei xu Yaolin xu Veronika Grzimek Andrea Martin Thorsten Schultz Patrícia ARusso yan lu Norbert Koch Nicola Pinna Department of Chemistry IRIS Adlershof and the Center for the Science of Materials BerlinHumboldt-Universität zu BerlinBrook-Taylor-Str.212489 BerlinGermany Department of Electrochemical Energy Storage Helmholtz-Zentrum Berlin für Materialien und EnergieHahn-Meitner-Platz 114109 BerlinGermany Institut für Physik and IRIS Adlershof Humboldt-Universität zu BerlinBrook-Taylor-Str.212489 BerlinGermany Joint Research Group of Molecular Systems Helmholtz-Zentrum Berlin für Materialien und Energie12489 BerlinGermany

Understanding the influence of electrode material’s morphology on electrochemical behavior is of great significance for the development of rechargeable batteries,however,such studies are often limited by the inability to precisely control the morphology of electrode ***,nanostructured titanium niobium oxides(TiNb_(2)O_(7))with three different morphologies(one-dimensional(1D),two-dimensional(2D),and three-dimensional(3D))were synthesized via a facile microwave-assisted solvothermal *** influence of the morphological dimension of TiNb_(2)O_(7) as electrode material on the electrochemical performance in Li-ion batteries(LIBs)and the underlying correlation with the electrochemical kinetics were studied in detail.2D TiNb_(2)O_(7)(TNO-2D)shows a superior rate capability and cycling stability,associated with improved kinetics for charge transfer and Li-ion diffusion,compared to the 1D and 3D *** X-ray diffraction measurements reveal the structural stability and crystallographic evolution of TNO-2D upon lithiation and delithiation and correlate the Li-ion diffusion kinetics with the lattice evolution during battery charge and ***,carbon-coated TNO-2D achieves enhanced rate capability(205 mAh·g^(-1) at 50 C)and long-term cycling stability(87%after 1000 cycles at 5 C).This work provides insights into the rational morphology design of electrode materials for accelerated charge transfer and enhanced fast-charging capability,pushing forward the development of electrode materials for high-power rechargeable batteries in future energy storage.

关键词： morphological dimension electrochemical kinetics lithium-ion batteries TiNb_(2)O_(7) structural evolution

Revealing the role of honokiol in human glioma cells by RNA-seq analysis

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BIOCELL 2024年第6期48卷 945-958页

作者： YUNBAO GUO xu LIU QI xu XIAOTONG ZHOU JIAWEI LIU yanyan xu yan lu HAIyan LIU The Department of Neurosurgery First Hospital of Jilin UniversityChangchun130021China The Department of Anatomy College of Basic Medical SciencesJilin UniversityChangchun130021China The Third College of Clinical Medicine Jilin UniversityChangchun130021China

Background:Glioma is a kind of tumor that easily deteriorates and originates from glial cells in nerve *** is a bisphenol compound that is an essential monomeric compound extracted from the roots and bark of Magnoliaceae *** also has anti-infection,antitumor,and immunomodulatory *** this study,we found that honokiol induces cell apoptosis in the human glioma cell lines U87-MG and ***,the mechanism through which honokiol regulates glioma cell apoptosis is still ***:We performed RNA-seq analysis of U251-MG cells treated with honokiol and control ***-protein interaction(PPI)network analysis was performed,and the 10 top hub unigenes were examined via real-time quantitative ***,MAPK signaling and ferroptosis were detected via western ***:332 differentially expressed genes(DEGs)were found,comprising 163 increased and 169 decreased *** of the DEGs revealed that various biological processes were enriched,including‘response to hypoxia’,‘cerebellum development cellular response to hypoxia,’‘iron ion binding,’‘oxygen transporter activity,’‘oxygen binding,’‘ferric iron binding,’and‘structural constituent of cytoskeleton.’Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis revealed that the DEGs were enriched in the following pathways:‘mitogen-activated protein kinases(MAPK)’,‘Hypoxia-inducible factor 1(HIF-1)’,‘ferroptosis,’‘Peroxisome proliferator-activated receptor(PPAR),’‘Phosphatidylinositol-4,5-bisphosphate 3-kinase(PI3K)-protein kinase B(Akt),’and‘phagosome.’Among these pathways,the MAPK signaling pathway and ferroptosis were veriﬁ***:This study revealed the potential mechanism by which honokiol induces apoptosis and provided a comprehensive analysis of DEGs in honokiol-treated U251-MG cells and the associated signaling *** data could lead to new ideas for future research and therapy for patients with glioma.

关键词： Human glioma Honokiol RNA-seq Apoptosis Ferroptosis MAPK

Design of Robust Var Reserve Contract for Enhancing Reactive Power Ancillary Service Market Efficiency

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CSEE Journal of Power and Energy Systems 2024年第2期10卷 767-771页

作者： Yunyang Zou yan xu School of Electrical and Electronic Engineering Nanyang Technological UniversitySingapore 639798Singapore

In a deregulated Var market, market power issue is more serious than in an energy market since reactive power cannot be transmitted over long distances. This letter designs a multi-timescale Var market framework, where market power that may arise in the hourly-ahead Var support service market due to system configuration deficiency and market structure flaws can be eliminated by day-ahead contract-based Var reserve service market. Settlement of day-ahead Var reserve contract is formulated as a two-stage robust optimization (TSRO) model considering worst case of uncertainty realization and potential market power that may arise in hourly-ahead market. TSRO with integer recourses is then solved by a new column and constraint generation algorithm. Results show a robust Var reserve contract can fully eliminate market power, and prevent suppliers from manipulating market prices.

关键词： Market efficiency market power reactive power ancillary service two-stage robust optimization Var reserve