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Acta Metallurgica Sinica(English Letters) 1998年第6期11卷 477-484页

作者： Q.Gao Y.X.Zhao L.X.cai Southwest Jiaotong Univ Chengdu China

Based on the test results obtained from the single-step test and the incremental-step test at room temperature and 240℃, a probabilistic assessment of temperature effects on the cyclic stress-strum response and the fatigue life of 1Cr18Ni9Ti steel weld metal is performed. In orber to assess the temperature effect on cyclic stress amplitude where there is a scatter of the material cyclic constitution, a probabilistic assessment approach on the basis of probabilistic modified Ramberg-Osgood relations is *** investigation shows that the cyclic stress amplitude and the scatter of cyclic stress amplitude data are decreased at 240℃. Similarly, from the consideration of the fatigue life scatter a probabilistic assessment of temperature effect on the fatigue life is suggested on the basis of probabilistic Langer S-N relations. The investigation shows that the crack initiation life is increased and the scatter of crack initiation life data is decreased at 240℃.

关键词： 1Cr_(18)Ni_9Ti stainless steel weld metal low cycle fatigue temperature effect probabilistic assessment

A Correction and Comments on“Multi-Scale Deep Neural Network(MscaleDNN)for Solving Poisson-Boltzmann Equation in Complex ***,28(5):1970–2001,2020”

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Communications in Computational Physics 2023年第5期33卷 1509-1513页

作者： Lulu Zhang Wei cai Zhi-Qin John Xu Institute of Natural Sciences and School of Mathematical Sciences Shanghai Jiao Tong UniversityShanghai200240China Department of Mathematics Southern Methodist UniversityDallasTX 75275USA

This note provides a correction of a missing weight constant in the MscaleDNN formula and some comments on the performance of the corrected algorithm.

关键词： Multi-scale DNN PDE solver deep learning

Sorafenib after resection improves the outcome of BCLC stage C hepatocellular carcinoma

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World Journal of Gastroenterology 2016年第15期22卷 4034-4040页

作者： Jiang Li Yu Hou Xiao-Bei cai Bin Liu Department of Hepatobiliary Surgery The First Affiliated Hospital of Kunming Medical University Kunming 650032 Yunnan Province China Department of Oncology Radiotherapy The Third Affiliated Hospital of Kunming Medical University Tumor Hospital of Yunnan province Kunming 650181 Yunnan Province China

AIM: To evaluate whether sorafenib use after resection impacts tumor relapse and survival in Barcelona Clinic Liver Cancer(BCLC) stage C hepatocellular carcinoma(HCC).METHODS: This retrospective study enrolled 36 male BCLC stage C HCC patients with portal vein thrombus and Child-Pugh class A liver function. Twentyfour patients received only surgical resection(SR), and 12 patients received oral sorafenib within 30 d after surgery. The primary outcomes were time to progression(TTP)(the time from surgical resection until HCC recurrence or extrahepatic metastases) and overall survival(OS). The secondary outcome was the rate of postoperative recurrence or metastasis. TTP and OS were analyzed using Kaplan Meier ***: There were no significant differences between the two groups in the serum levels of alpha-fetoprotein, copies of hepatitis B virus-DNA, preoperative laboratory results, degree of hepatic fibrosis, types of portal vein tumor thrombus, number of satellite lesions, tumor diameter, pathological results, volume of blood loss, volume of blood transfusion, or surgery time(all P > 0.05). Patients in the SR + sorafenib group had a significantly longer TTP(29 mo vs 22 mo, P = 0.041) and a significantly longer medianOS(37 mo vs 30 mo, P = 0.01) compared to patients in the SR group. The SR group had 18 cases(75%) of recurrence/metastasis while the SR + sorafenib group had six cases(50%) of recurrence/metastasis. A total of 19 patients died after surgery(five in the SR + sorafenib group and 14 in the SR group). The most common sorafenib-related adverse events were skin reactions, diarrhea, and hypertension, all of which were resolved with ***: Sorafenib after SR was well-tolerated. Patients who received sorafenib after SR had better outcomes compared to patients who received only SR.

关键词： Hepatocellular carcinoma Survival Hepatic resection Sorafenib Recurrence

白鲜不同生育时期营养元素积累规律及分配特征

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东北林业大学学报 2025年第1期53卷 35-42页

作者：邵财孙海关一鸣金桥王秋霞张亚玉中国农业科学院特产研究所长春130112 成都大学

以3年生白鲜(Dictamnus dasycarpus)为研究对象,通过测定白鲜不同生育时期根、茎、叶的干质量及营养元素含量,分析白鲜不同生育时期营养元素积累规律及分配特征,为白鲜科学精准施肥提供理论依据。结果表明:白鲜在生长过程中,不同营养元... 详细信息

以3年生白鲜(Dictamnus dasycarpus)为研究对象,通过测定白鲜不同生育时期根、茎、叶的干质量及营养元素含量,分析白鲜不同生育时期营养元素积累规律及分配特征,为白鲜科学精准施肥提供理论依据。结果表明:白鲜在生长过程中,不同营养元素的积累量由大到小的顺序为氮(N)、钙(Ca)、磷(P)、钾(K)、镁(Mg)、铁(Fe)、锰(Mn)、锌(Zn)、铜(Cu);在生长初期,N、P、K质量分数相对较高,植物对N、P、K元素的需求较大;出苗期至花蕾期,白鲜根中N、P、K的积累量分配比例明显降低,茎叶中积累量分配比例明显增加;从果前期开始,白鲜茎叶中Ca、Mg质量分数和积累量显著增加,在茎叶中分配比例相对较高;果前期和果中期茎叶中Fe、Mn质量分数显著增加,Fe、Mn元素积累量在果中期相对较高,茎叶中分配比例有所增加;根中Zn质量分数从果前期至果中期显著增加,整株积累量显著增大,果中期在根中分配比例达到最大,白鲜茎叶中Cu、Zn质量分数在花蕾期相对较高,在茎叶中的分配比例达到最大。因此,白鲜出苗期至花蕾期需要补充大量元素(N、P、K)及微量元素(Cu、Zn),果前期至果熟期需要补充中量元素(Ca、Mg)和微量元素(Fe、Mn、Zn)。

关键词：白鲜营养元素积累分配合理施肥

Expert consensus on interventional therapy for traumatic splenic bleeding

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Journal of Interventional Medicine 2020年第3期3卷 109-117页

作者： Huangxing cai lingyun Zhang Hua Xiang Department of Interventional Vascular Surgery Hunan Provincial People's HospitalChangshaHunan Province410005China

This study aims to introduce the diagnosis and treatment processes of traumatic splenic bleeding and explain its emergency,medical,interventional,and surgical ***,this study aims to summarize the indications and contr... 详细信息

关键词： Consensus Interventional therapy Traumatic Splenic bleeding

Cuproptosis:lipoylated TCA cycle proteins-mediated novel cell death pathway

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Signal Transduction and Targeted Therapy 2022年第6期7卷 1872-1874页

作者： Su-Ran Li Lin-Lin Bu Lulu cai The State Key Laboratory Breeding Base of Basic Science of Stomatology(Hubei-MOST)&Key Laboratory of Oral Biomedicine Ministry of Education School and Hospital of StomatologyWuhan UniversityWuhan 430072China Department of Oral Maxillofacial Head Neck Oncology School and Hospital of StomatologyWuhan UniversityWuhanHubei 430079China Department of Pharmacy Personalized Drug Therapy Key Laboratory of Sichuan ProvinceSichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengdu 610072China

In a recent study published in Science,Tsvetkov et *** a light on a new form of cell death,copper-dependent cell death(termed cuproptosis).They defined“cuproptosis”as a nonapoptotic cell death *** have demonstrated that copper directly binds to lipoylated components of the tricarboxylic acid(TCA)*** aggregation of these copper-bound,lipoylated mitochondrial proteins and subsequent Fe-S cluster protein loss triggered proteotoxic stress and a distinct form of cell death.

关键词： death copper aggregation

Superconductivity of Pb films studied with superconducting Pb tips

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Science China(Physics,Mechanics & Astronomy) 2019年第1期62卷 99-102页

作者： FangLiang cai PengJu Li Kun Xie Rui Tang ShengYong Qin CAS Key Laboratory of Strongly-Coupled Quantum Matter Physics and Department of Physics University of Science and Technology of China International Center for Quantum Design Hefei National Laboratory for Physical Sciences at Microscale and Synergetic Innovation Center of Quantum Information and Quantum Physics University of Science and Technology of China

Studying the superconductivity of materials using scanning tunneling microscopy (STM)remains a challenge to this day .In this regard,the stability of the tunneling junction is a critical factor,together with the spectroscopy resolution. Using a superconducting tip is an effective way to increase the resolution of the obtained tunneling spectra .For example,Pan et *** that the use of superconducting Nb tips resulted in extremely high resolution scanning tunneling spectroscopy (STS).Furthermore,Nb tips have been successfully applied to several systems to acquire improved resolutions .

关键词： Studying Superconductivity films

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非均匀强激光场下正负电子对的产生

原子与分子物理学报 2025年第2期42卷 117-123页

作者：落彩青任云亮吾拉依木江·司提瓦力地新疆大学物理科学与技术学院乌鲁木齐830046

随着强激光技术领域的不断突破,使得能量转化成物质的施温格过程的实验指日可待.在这样的背景下,在接近实际强激光的模型中理论研究施温格效应至关重要.本文采用量子场论模拟方法在非均匀电场中研究施温格效应的空间特性.首先,发现在能... 详细信息

随着强激光技术领域的不断突破,使得能量转化成物质的施温格过程的实验指日可待.在这样的背景下,在接近实际强激光的模型中理论研究施温格效应至关重要.本文采用量子场论模拟方法在非均匀电场中研究施温格效应的空间特性.首先,发现在能量保持不变的情况下电场的空间尺度显著影响正负电子对的产生率、动量和空间分布.正负电子对的动量和空间分布显示,当电场的空间尺度增大时,因为电场强度变小,所以产生的正负电子对无法及时被分开,抑制正负电子对的产生.最后,用连续性方程研究正负电子对的产生位置分布,发现正负电子对的产生位置分布与电场强度分布是对应的,电子和正电子的产生位置分离一个康普顿波长.此研究结果展示了施温格效应的空间特性,同时解释了弱电场下施温格效应的抑制机制.这些结论在人们常采用的均匀电场近似研究中无法得到.我们的研究对检测施温格实验中的正负电子对具有重要的指导意义.

关键词：强激光施温格效应量子场论模拟方法非均匀电场空间分布

Bifurcation and catastrophe of seepage flow system in broken rock

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Mining Science and Technology 2009年第1期19卷 1-7页

作者： MIAO Xie-xing LI Shun-cai CHEN Zhan-qing School of Sciences China University of Mining ＆ Technology Xuzhou Jiangsu 221008 China School of Mechanical and Electrical Engineering Xuzhou Normal University Xuzhou Jiangsu 221116 China

The study of dynamical behavior of water or gas flows in broken rock is a basic research topic among a series of key projects about stability control of the surrounding rocks in mines and the prevention of some disasters such as water inrush or gas outburst and the protection of the groundwater resource. It is of great theoretical and engineering importance in respect of promo- tion of security in mine production and sustainable development of the coal industry. According to the non-Darcy property of seepage flow in broken rock dynamic equations of non-Darcy and non-steady flows in broken rock are established. By dimensionless transformation, the solution diagram of steady-states satisfying the given boundary conditions is obtained. By numerical analysis of low relaxation iteration, the dynamic responses corresponding to the different flow parameters have been obtained. The stability analysis of the steady-states indicate that a saddle-node bifurcaton exists in the seepage flow system of broken rock. Consequently, using catastrophe theory, the fold catastrophe model of seepage flow instability has been obtained. As a result, the bifurcation curves of the seepage flow systems with different control parameters are presented and the standard potential function is also given with respect to the generalized state variable for the fold catastrophe of a dynamic system of seepage flow in broken rock.

关键词： broken rock non-Darcy flow stability saddle-node bifurcation fold catastrophe

Analysis of functional hub genes indicates DLGAP5 is linked to lung adenocarcinoma prognosis

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BIOCELL 2023年第11期47卷 2453-2469页

作者： HAOSHENG ZHENG RUIJUN LIN WEIJIE cai YUZHEN ZHENG XINGPING yanG ZUI LIU FEI QIN YONGJIE cai XIANYU QIN HONGYING LIAO Department of Thoracic Surgery Thoracic Cancer CenterThe Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhou510655China Department of Thoracic Surgery The First Affiliated Hospital of Shantou University Medical CollegeShantou515041China Department of Microbiology Zhongshan School of MedicineKey Laboratory for Tropical Diseases Control of the Ministry of EducationSun Yat-sen UniversityGuangzhouChina

Introduction:The difficulty in treating lung adenocarcinoma(LUAD)is caused by a shortage of knowledge about the biological mechanisms and a lack of treatment ***:The aim of this study was to identify a valuable molecular target for the treatment of ***:Using multiple databases,we screened for hub genes in LUAD using Cytoscape and explored the expression and prognosis of DLG associated protein 5(DLGAP5)in *** investigated the genetic variation,functional enrichment,and epigenetic activity of ***,we evaluated the relationship between the tumor microenvironment(TME)and ***:Our study identified 10 hub genes in LUAD:CDC45,KIAA0101,DLGAP5,CDT1,NCAPG,CCNB1,CDCA5,CDC20,KIF11,and *** discovered that DLGAP5 was overexpressed and associated with poor prognosis in ***5 exhibited an overall genetic variation frequency of 2%,and its DNA promoter was hypomethylated in LUAD(p<0.05).The expression of DLGAP5 in LUAD showed a positive correlation with the majority of N6-methyladenosine(m6A)-methylation ***,DLGAP5 was primarily associated with the cell cycle in ***,there was a significant favorable association between DLGAP5 and CD274,CTLA4,HAVCR2,and LAG3 in ***:DLGAP5 may be a therapeutic target for LUAD,as it affects cancer cells proliferation and development through the regulation of cell-cycle checkpoints and modulation of immune cell infiltration and immune checkpoints in the TME.

关键词： DLGAP5 Lung adenocarcinoma Prognosis Tumor microenvironment Hub genes