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Parameters of ocular fundus on spectral-domain optical coherence tomography for glaucoma diagnosis

International Journal of Ophthalmology(English edition) 2017年第6期10卷 982-991页

作者： Yu-lin Tao Li-Ming Tao Zheng-Xuan Jiang He-Ting Liu Kun Liang Mo-Han Li Xuan-Sheng Zhu yan-lin ren Bing-Jie Cui Department of Ophthalmology the First People＇s Hospital of Jiujiang City Jiujiang 332000 Jiangxi Province China Department of Ophthalmology the Second Affiliated Hospital of Anhui Medical University Hefei 230000 Anhui Province China 3Department of Ophthalmology the Fuyang Affiliated Hospital of Anhui Medical University Fuyang 236000 Anhui Province China

In this review, we summarize the progression of several parameters assessed by spectral-domain optical coherence tomography （SD-OCT） in recent years for the detection of glaucoma. Monitoring the progression of defects in the retinal nerve fiber layer （RNFL） thickness is essential. Imaging and analysis of retinal ganglion cells （RGCs） and inner plexiform layer （IPL）, respectively, have been of great importance. Optic nerve head （ONH） topography obtained from 3D SD-OCT images is another crucial step. Other important assessments involve locating the Bruch＇s membrane opening （BMO）, estimating the optic disc size and rim area, and measuring the lamina cribrosa displacement. Still other parameters found in the past three years for glaucoma diagnosis comprise central retinal artery resistive index, optic disc perfusion in optical coherence tomography angiography （OCTA） study, peripapillary choroidal thickness, and choroidal area in SD-OCT. Recently, several more ocular fundus parameters have been found, and compared with the earlier parameters to judge the accuracy of diagnosis. While a few of these parameters have been widely used in clinical practice, a fair number are still in the experimental stage.

关键词： glaucoma progression retinal nerve fiberlayer ganglion cells macular thickness optic nerve head lamina cribrosa optical coherence tomography

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Relations Between Red Edge Characteristics and Agronomic Parameters of Crops

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Pedosphere 2004年第4期14卷 467-474页

作者： TANGyan-lin WANGren-Chao HUANGJing-Feng InstituteofAgricultureRemoteSensingandInformationSystemApplication ZhejiangUniversityHangzhou310029

The hyperspectral reflectance of the canopy and the leaves on the main stemfor six varieties, two each of rice corn, and cotton crops, were measured at different growth stageswith an ASD FieldSpec Pro FR^(TM) to analyze red edge characteristics forleaf area indices (LAI),aboveground biomass, as well as the chlorophyll, carotenoid, and nitrogen content, emphasizingcomparative differences on the red edge parameters. The results showed a 'double peak' phenomenonfor the red edge of the canopy spectra but not for the leaves. There were 'increase' and 'decrease'change rules for the red edge position, lambda_r, the red edge slope, D lambda_r, and the red edgearea, S_r, of the canopy spectra for all 3 crops with a 'blue shift' for lambda_r of the leafspectra for all 3 crops as the development stages progressed. For rice, corn, and cotton the LAI andfresh leaf mass had highly significant correlations (P < 0.01) to the red edge parameters lambda_r,D lambda_r, and S_r of their canopy spectra. Additionally, for all crops the chlorophyll-a,chlorophyll-b, total chlorophyll, and carotenoid content of the leaves all had highly significant (P< 0.01) correlations to their lambda_r. For rice, the nitrogen content of the leaves in g kg^(-1)and phytomassfor a unit area of land in g m^(-2) also had a highly significant (P < 0.01)correlation to lambda_r, D lambda_r lambda_r, and S_r of the canopy spectra.

关键词： agronomic parameter crop red edge parameter correlation analysis

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Detection of EEG signals in normal and epileptic seizures with multiscale multifractal analysis approach via weighted horizontal visibility graph

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Chinese Physics B 2023年第11期32卷 401-407页

作者：马璐任彦霖何爱军程德强杨小冬 School of Information and Control Engineering China University of Mining and TechnologyXuzhou 221116China Suzhou Vocational and Technical College Suzhou 234000China School of Computer Science and Technology China University of Mining and TechnologyXuzhou 221116China School of Electronic Science and Engineering Nanjing UniversityNanjing 210023China

Electroencephalogram(EEG) signals contain important information about the regulation of brain system. Thus, automatic detection of epilepsy by analyzing the characteristics obtained from EEG signals has important research implications in the field of clinical medicine. In this paper, the horizontal visibility graph(HVG) algorithm is used to map multifractal EEG signals into complex networks. Then, we study the structure of the networks and explore the nonlinear dynamics properties of the EEG signals inherited from these networks. In order to better describe complex brain behaviors, we use the angle between two connected nodes as the edge weight of the network and construct the weighted horizontal visibility graph(WHVG). In our studies, fractality and multifractality of WHVG are innovatively used to analyze the structure of related networks. However, these methods only analyze the reconstructed dynamical system in general characterizations,they are not sufficient to describe the complex behavior and cannot provide a comprehensive picture of the system. To this effect, we propose an improved multiscale multifractal analysis(MMA) for network, which extends the description of the network dynamics features by focusing on the relationship between the multifractality and the measured scale-free ***, neural networks are applied to train the above-mentioned parameters for the classification and identification of three kinds of EEG signals, i.e., health, interictal phase, and ictal phase. By evaluating our experimental results, the classification accuracy is 99.0%, reflecting the effectiveness of the WHVG algorithm in extracting the potential dynamic characteristics of EEG signals.

关键词： epilepsy EEG signal horizontal visibility graph complex network

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Jiao-tai-wan Up-regulates Hypothalamic and Peripheral Circadian Clock Gene Cryptochrome and Activates PI3K/AKT Signaling in Partially Sleep-deprived Rats

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Current Medical Science 2018年第4期38卷 704-713页

作者： Wen-ya HUANG Xin ZOU Fu-er LU Hao SU Chu ZHANG yan-lin ren Ke FANG Li-jun XU Kai- fu WANG Qing-jie CHEN Hui DONG Institute of Integrated Traditional Chinese and Western Medicine Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China Department of Biochemistry and Molecular Biology Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China

This study aims to explore the effect and mechanism of Jiao-tai-wan （JTW） on systemic and tissue-specific inflammation and insulin resistance in obesity-resistant （OR） rats with chronic partial sleep deprivation （PSD）. OR rats with PSD were orally given JTW and Estazolam for 4 weeks. The amount of food intake and metabolic parameters such as body weight increase rate, fasting plasma glucose （FPG）, fasting insulin （FINS）, homeostasis model assessment-insulin resistance （HOMA-IR） and plasma inflammatory markers were measured. The expression levels of circadian proteins cryptochrome 1 （Cryl） and cryptochrome 2 （Cry2） in hypothalamus, adipose and liver tissues were also determined. Meanwhile, the mRNA expression of inflammatory markers, activity of nuclear factor kappa B （NF-κB） p65 protein, as well as the expression levels of insulin signaling pathway proteins in hypothalamus, adipose and liver tissues were measured. Additionally, cyclic adenosine 3＇, 5＇-monophosphate （cAMP） and activity of vasodilator-stimulated phosphoprotein （VASP） in hypothalamus tissue were measured. JTW significantly decreased the body weight increase rate and food intake, ameliorated systemic inflammation and insulin resistance. JTW effectively ameliorated inflammation and increased PI3K/AKT signaling activation in hypothalamus, adipose and liver. Interestingly, all these changes were associated with the up-regulation of circadian gene Cryl and Cry2 protein expression. We also found that in hypothalamus tissue of PSD rats, down-regulation of Cryl and Cry2 activated cAMP/PKA signaling and then led to inflammation, while JTW inhibited this signaling. These results suggested that JTW has the beneficial effect on ameliorating inflammation and insulin resistance in partially sleep-deprived rats by up-regulating Cry expression.

关键词： Jiao-tai-wan PI3K/AKT signaling cryptochrome sleep deprivation inflammation insulin resistance

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Martensite Transformation and Its Control in DP,TRIP and TWIP Steels

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Journal of Iron and Steel Research International 2011年第S1期18卷 200-207页

作者： LI lin 1,GAO Yi 2,SHI Wen 1,LIU ren-dong 2,HE yan-lin 1,FU ren-yu 1,ZHANG Mei 1,WANG Hua 1 (1.School of Materials Science and Engineering,Shanghai University,Shanghai 200072,China 2.Ansteel Company,Anshan 114001 China Corresponding Author:School of Materials Science and Engineering,Shanghai University,P.O.Box 15,149 yanchang Road,Shanghai 200072,China) Shanghai Univ Sch Mat Sci & Engn Shanghai 200072 Peoples R China Ansteel Co Anshan 114001 Peoples R China

Designing of alloy concept and process for DP,TRIP and TWIP steels stressing at martensite transformation are *** DP steel,austenite volume percent and its carbon content at different intercritical temperatures are calculated as well as the tensile strength of the steel,which meet well with the experimental *** condition for dissolution of carbide is discussed by experiments and predicted by kinetic *** sample TRIP steels are prepared and their concentration profiles are calculated showing different diffusion characteristics of *** also shows carbon enrichment is successful in this stage through the quick diffusion of carbon from ferrite to *** order to maintain the austenite stability or to prevent precipitation of cementite,minimum cooling rate from the intercritical zone to over aging stage is obtained through kinetic *** transformation is estimated,which indicates the carbon rerichment from ferrite of bainite structure to austenite in this stage is also *** HCP martensite transformation and the strain induced martensite transformation in TWIP steel is *** between transformation and mechanical properties in the steel is also mentioned.

关键词： martensite transformation DP TRIP and TWIP steels thermal HCP martensite transformation

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肾癌组织Notch 1、HIF-1α的表达及其与肿瘤临床分期的相关性

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第二军医大学学报 2009年第8期30卷 970-971页

作者：闫润林王林辉孙颖浩第二军医大学长海医院泌尿外科上海200433

目的:探讨肾癌组织Notch1、HIF-1α的表达及意义。方法:应用组织芯片、免疫组化染色法比较肾癌(n=60)及正常肾组织(n=30)中Notch1、HIF-1α蛋白的表达差异,分析二者表达与肿瘤临床分期的相关性。结果:肾癌组织Notch1、HIF-1α阳性表达... 详细信息

目的:探讨肾癌组织Notch1、HIF-1α的表达及意义。方法:应用组织芯片、免疫组化染色法比较肾癌(n=60)及正常肾组织(n=30)中Notch1、HIF-1α蛋白的表达差异,分析二者表达与肿瘤临床分期的相关性。结果:肾癌组织Notch1、HIF-1α阳性表达率高于正常肾组织(40.0%vs13.3%,58.3%vs0%,P<0.05);TNM分期Ⅲ～Ⅳ期肾癌组织Notch1、HIF-1α阳性表达率高于Ⅰ～Ⅱ期(27.5%vs65.0%,45.0%vs85.0%,P<0.05)。结论:肾癌组织中Notch1、HIF-1α表达均高于正常肾组织,且与肿瘤临床分期有关,二者对判断临床预后可能具有一定价值。

关键词：肾肿瘤 Notch 1 HIF-1α 肿瘤分期

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Gradient‑Layered MXene/Hollow Lignin Nanospheres Architecture Design for Flexible and Stretchable Supercapacitors

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Nano-Micro Letters 2025年第2期17卷 447-462页

作者： Haonan Zhang Cheng Hao Tongtong Fu Dian Yu Jane Howe Kaiwen Chen Ning yan Hao ren Huamin Zhai Jiangsu Provincial Key Lab of Sustainable Pulp and Paper Technology and Biomass Materials NanJing Forestry UniversityNanjing 210037People’s Republic of China Department of Chemical Engineering and Applied Chemistry University of Toronto200 College StreetTorontoON M5S 3E5Canada Department of Materials Science and Engineering University of Toronto184 College StreetTorontoON M5S 3E4Canada College of Materials Science and Engineering Nanjing Forestry UniversityNanjing 210037People’s Republic of China

With the rapid development of flexible wearable electronics,the demand for stretchable energy storage devices has *** this work,a novel gradient-layered architecture was design based on single-pore hollow lignin nanospheres(HLNPs)-intercalated two-dimensional transition metal carbide(Ti_(3)C_(2)T_(x) MXene)for fabricating highly stretchable and durable *** depositing and inserting HLNPs in the MXene layers with a bottom-up decreasing gradient,a multilayered porous MXene structure with smooth ion channels was constructed by reducing the overstacking of MXene ***,the micro-chamber architecture of thin-walled lignin nanospheres effectively extended the contact area between lignin and MXene to improve ion and electron accessibility,thus better utilizing the pseudocapacitive property of *** these strategies effectively enhanced the capacitive performance of the *** addition,HLNPs,which acted as a protective phase for MXene layer,enhanced mechanical properties of the wrinkled stretchable electrodes by releasing stress through slip and deformation during the stretch-release cycling and greatly improved the structural integrity and capacitive stability of the *** electrodes and symmetric flexible all-solid-state supercapacitors capable of enduring 600%uniaxial tensile strain were developed with high specific capacitances of 1273 mF cm^(−2)(241 F g^(−1))and 514 mF cm^(−2)(95 F g^(−1)),***,their capacitances were well preserved after 1000 times of 600%stretch-release *** study showcased new possibilities of incorporating biobased lignin nanospheres in energy storage devices to fabricate stretchable devices leveraging synergies among various two-dimensional nanomaterials.

关键词： Hollow lignin nanospheres MXene Gradient-layered architecture Wrinkled electrodes Stretchable supercapacitors

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A basic study on wafer subsurface damage at multi-wire saw

A basic study on wafer subsurface damage at multi-wire saw

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第14届全国晶体生长与材料学术会议

作者： LI yan-lin , ren Bing-yan , yanG Jian-kun (School of Material Science and Engineering, Hebei University of Technology, Tianjin 300130, China )

Wiresaw is widely known as the technology at present, capable of meeting both semiconductor and photovoltaic (PV) industry’s requirements for producing wafers from large diameter ingots and very thin

关键词： Wire saw Wafer slicing subsurface damage

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探讨围产期乙型肝炎病毒的垂直传播及预防策略

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生殖与避孕 2010年第1期30卷 67-71页

作者：任雁林陈书玲河北北方学院附属第一医院妇产科张家口075000

世界上约20亿人血清学检查证实是HBV的感染者，其中3．5亿人属于慢性HBV感染，每年至少有100万感染者死于肝硬化或肝癌。中国是HBV感染高流行区，全球33％感染者在中国，约有7．5亿人被HBV感染，其中1．2-1．3亿人长期携带HBV。据中国... 详细信息

世界上约20亿人血清学检查证实是HBV的感染者，其中3．5亿人属于慢性HBV感染，每年至少有100万感染者死于肝硬化或肝癌。中国是HBV感染高流行区，全球33％感染者在中国，约有7．5亿人被HBV感染，其中1．2-1．3亿人长期携带HBV。据中国疾病预防控制中心统计，

关键词：乙型肝炎病毒(HBV) 垂直传播预防策略

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Carotid intima-media thickness and stiffness in T2DM and IGT patients

Carotid intima-media thickness and stiffness in T2DM and IGT...

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第二届长三角超声医学论坛暨2009年浙江省超声医学学术年会

作者： Department of Ultrasonography,Ruijin Hospital,Shanghai Jiaotong University Medical School Shanghai 200025,China yan-ping LIU Yin ZHU yan-yan lin Xin-ping ren Wei-wei ZHAN

Background Diabetes and impaired glucose tolerance(IGT) are associated with higher cardiovascular mortality. Objective To investigate carotid intima-media thickness(IMT) and quantitative carotid stiffness (QCS) index ...

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