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Design of adiabatic two's complement multiplier-accumulator based on CTGAL

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第2期10卷 172-178页

作者： Peng-jun WANG Jian xu Shi-yan YING Institute of Circuits and Systems Ningbo University Ningbo 315211 China College of Information Engineering Zhej iang University of Technology Hangzhou 310014 China

We propose a new design scheme for a Booth encoder based on clocked transmission gate adiabatic logic(CTGAL). In the new design the structural complexity of the Booth encoder is reduced while the speed of the multiplier is improved. The adiabatic two's complement multiplier-accumulator(MAC) is furthermore a design based on the CTGAL. The computer simulation results indicate that the designed circuit has the correct logic function and remarkably less energy consumption compared to that of the MAC based on complementary metal oxide semiconductor(CMOS) logic.

关键词： CTGAL circuit Adiabatic circuit Booth arithmetic Multiplier Two's complement MAC

Peering into the Milky Way by FAST:Ⅲ.Magnetic fields in the Galactic halo and farther spiral arms revealed by the Faraday effect of faint pulsars

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Science China(Physics,Mechanics & Astronomy) 2022年第12期65卷 39-54页

作者： jun xu JinLin Han PengFei Wang Yi yan National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Astronomy University of Chinese Academy of SciencesBeijing 100049China

The Five-hundred-meter Aperture Spherical radio Telescope(FAST)is the most sensitive radio telescope for pulsar *** make polarimetric measurements of a large number of faint and distant pulsars using the *** present the new measurements of Faraday rotation for 134 faint pulsars in the Galactic *** improvements are also made for some basic pulsar parameters for 15 of *** analyse the newly determined rotation measures(RMs)for the Galactic magnetic fields by using these 134 halo pulsars,together with previously available RMs for pulsars and extragalactic radio sources and also the newly determined RMs for another 311 faint pulsars which are either newly discovered in the project of the Galactic Plane Pulsar Snapshot(GPPS)survey or previously known pulsars without *** RM tomographic analysis in the first Galactic quadrant gives roughly the same field strength of around 2μG for the large-scale toroidal halo magnetic *** scale height of the halo magnetic fields is found to be at least 2.7±0.3 *** RM differentiation of a large number of pulsars in the Galactic disk in the Galactic longitude range of 26°

关键词： magnetic fields interstellar medium pulsars

Phase Separation and Transport Behavior in La_(0.67-x)Sm_xSr_(0.33)MnO_3 System

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Chemical Research in Chinese Universities 2005年第6期21卷 707-713页

作者： LIU Ning yan Guo-qing xu Su-jun Department of Physics Suzhou College Suzhou 23400 P. R. China Structure Research Laboratory Science and Technology University of China Hefei 230026 P. R. China

The magnetic behavior and the transport behavior of La0.67-x Smx Sr0.33 MnO3 （x = 0. 00, 0. 10, 0. 20, 0. 30, 0. 40, 0. 50 and 0. 60 ） systems were studied through measuring the M-T curves, electron spin resonance （ ESR ） curves and ρ-T curves. The samples exhibit a long-range ferromagnetic order when x = 0. 00, 0. 10, a cluster-spin glass state when x = 0. 20 and 0. 30, and an anti-ferromagnetic state at low temperatures when x = 0. 40, 0. 50 and 0. 60. The samples of x = 0. 30 and 0.40 show phase separation at temperatures above Te. The transport behavior of the sample of x = 0. 60 becomes abnormal when the doping is high, and an insulator-metal transition occurs near To and then a metal-insulator transition occurs, which rarely appears in an ABO3 structure. It is concluded that the magnetic and electric behavior changes of the systems depend on the extra magnetism and lattice distortion effect induced by Sm doping.

关键词： Magnetic structure Phase separation Transport behavior Colossal magnetoresistance effect

计算机视觉技术赋能大学英语课堂展示中的学习投入研究

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新疆师范大学学报（哲学社会科学版） 2025年第2期46卷 144-151页

作者：谭苏燕王晋军广州大学外国语学院广东广州510010

学习投入是预测学习者学习效果的重要指标,学术界对其与课堂展示间的相关性研究鲜有涉猎。文本以某综合性大学303名非英语专业本科生为研究对象,采用人工智能与计算机视觉技术模型YOLOv7对大学英语课堂中的课堂展示实录进行学习投入多... 详细信息

学习投入是预测学习者学习效果的重要指标,学术界对其与课堂展示间的相关性研究鲜有涉猎。文本以某综合性大学303名非英语专业本科生为研究对象,采用人工智能与计算机视觉技术模型YOLOv7对大学英语课堂中的课堂展示实录进行学习投入多模态数据分析,并辅以问卷调查,形成双向印证。研究发现,学生课堂展示中的行为投入、认知投入和情感投入值均等于或高于3.78,投入结果均值达4.01,说明学生在课堂展示中的学习投入情况良好。此外,不同时段课堂展示对学生行为投入的影响显著,学生专注度及参与度在课堂前10分钟的课堂展示中效果最佳。文本为课堂展示的有效性提供了智能化、多模态、多维度的实证支持,为课堂教学的数智技术应用提供了新视角。

关键词：大学英语课堂展示学习投入计算机视觉技术展示时段

姜黄素对百草枯中毒大鼠肺组织胶原面积及TNF-α、IL-6、NE表达的影响

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中华急诊医学杂志 2017年第11期26卷 1252-1256页

作者：陈红纲杨蓉佳唐艳许筠冯友繁刘世杰张世魁候丽君甘肃省人民医院急诊科兰州730000 兰州市第二人民医院急诊科兰州730046

目的观察姜黄素对百草枯中毒大鼠肺组织胶原面积及TNF-α、IL-6、NE表达的影响，以探讨姜黄素治疗百草枯中毒的可能机制。方法SPF级Wistar大鼠108只，随机（随机数字法）分为空白对照组（B组）、百草枯染毒组（PQ组）、姜黄素治疗组（P... 详细信息

目的观察姜黄素对百草枯中毒大鼠肺组织胶原面积及TNF-α、IL-6、NE表达的影响，以探讨姜黄素治疗百草枯中毒的可能机制。方法SPF级Wistar大鼠108只，随机（随机数字法）分为空白对照组（B组）、百草枯染毒组（PQ组）、姜黄素治疗组（PC组），PQ组及PC组给予百草枯（50 mg/ kg）（北京华都生物科技）一次性灌胃染毒复制中毒模型，同时空白对照组给予等量生理盐水灌胃；灌胃30 min后，PC组给予姜黄素（sigma公司）200 mg/kg一次性腹腔注射，B组、PQ组注射等体积生理盐水，常规饲养。于3 d、7 d、14 d，行HE染色、Masson染色观察肺组织病理形态学、胶原纤维的分布及变化，酶联免疫吸附法检测血清肿瘤坏死因子（TNF-α）、白介素（IL-6）含量，免疫组织化学法观察肺组织中性粒细胞弹性蛋白酶（NE）的表达及变化。结果与B组比较，PQ组各时间点肺组织均有不同程度的肺泡炎，以7 d时最为严重；肺组织弥漫性纤维化，大量胶原纤维沉积，14 d胶原纤维沉积最严重；NE表达明显增强，14 d最明显。血清TNF-α、IL-6含量亦显著升高（P＜0.05，P＜0.01）；与PQ组比较，PC组各时间点肺泡炎及肺纤维化程度均有明显减轻，NE表达明显减弱，TNF-α、IL-6含量亦显著降低（P＜0.05）。结论抑制炎症因子及NE的表达，降低大鼠的肺泡炎和肺纤维化程度，可能是姜黄素治疗百草枯中毒肺的作用机制之一。

关键词：百草枯姜黄素病理形态胶原面积肿瘤坏死因子白介素-6 中性粒细胞弹性蛋白酶

Itch perception is reflected by neuronal ignition in the primary somatosensory cortex

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National Science Review 2022年第6期9卷 90-99页

作者： Xiao-jun Chen yan-He Liu Ning-Long xu yan-Gang Sun Institute of Neuroscience State Key Laboratory of Neuroscience Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of Sciences University of Chinese Academy of Sciences Shanghai Center for Brain Science and Brain-Inspired Intelligence Technology

Multiple cortical areas including the primary somatosensory cortex(S1) are activated during itch signal processing, yet cortical representation of itch perception remains unknown. Using novel miniature two-photon microscopic imaging in free-moving mice, we investigated the coding of itch perception in *** found that pharmacological inactivation of S1 abolished itch-induced scratching behavior, and the itch-induced scratching behavior could be well predicted by the activity of a fraction of layer 2/3 pyramidal neurons, suggesting that a subpopulation of S1 pyramidal neurons encoded itch perception, as indicated by immediate subsequent scratching behaviors. With a newly established optogenetics-based paradigm that allows precisely controlled pruritic stimulation, we found that a small fraction of S1 neurons exhibited an ignition-like pattern at the detection threshold of itch perception. Our study revealed the neural mechanism underlying itch perceptual coding in S1, thus paving the way for the study of cortical representation of itch perception at the single-neuron level in freely moving animals.

关键词： itch perception primary somatosensory cortex miniature two-photon microscopic imaging

广东省就业流动人口代谢综合征患病率及影响因素研究

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华南预防医学 2016年第6期42卷 501-509页

作者：许燕君许晓君刘涛夏亮宋秀玲周少恩徐浩锋杨翌广东药科大学公共卫生学院广东广州510310 广东省疾病预防控制中心广东省疾病预防控制中心广东省公共卫生研究院

目的分析广东省18—59岁就业流动人口代谢综合征（MS）的流行情况及影响因素，为采取相应的干预措施提供依据。方法2012年采用分层多阶段整群抽样方法抽取广东省18-59岁就业流动人12作为研究对象，采用面对面方式进行问卷调查、体格检... 详细信息

目的分析广东省18—59岁就业流动人口代谢综合征（MS）的流行情况及影响因素，为采取相应的干预措施提供依据。方法2012年采用分层多阶段整群抽样方法抽取广东省18-59岁就业流动人12作为研究对象，采用面对面方式进行问卷调查、体格检查以及采集血样，调查内容包括基本信息、吸烟、饮酒、饮食、身体活动状况、身高、体重、腰围、血压、血糖、血脂以及健康状况等。采用2005国际糖尿病联合会（IDF2005）诊断标准对MS进行诊断。利用R软件，采用混合线性模型对MS影响因素进行分析。结果本研究共调查18-59岁就业流动人口1753人，其中男性932人（占53．17％），女性821人（占46．83％）；城市893人（占50．9％），农村860人（占49．1％）。MS总患病率为11．2％，女性患病率（13．0％）高于男性（9．7％），城市患病率（13．4％）高于农村（9．O％），差异均有统计学意义（P〈0．05或P〈0．01）。随着年龄增加，MS患病率随之增加（P〈0．01）。多因素分析结果显示，与不吸烟者相比，戒烟者、吸烟1—9、10—19、≥20支／d者MS患病风险升高，其OR值分别为2．5（1．5—4．3）、3．0（1．9-4．8）、1．9（1．1-3．2）和1．8（1．1—2．9）；与不饮酒相比，饮酒〈1、1—2、〉2坎／周者患病风险升高，其OR值分别为4．4（3．3—6．0）、3．0（1．9-4．9）和3．1（2．0-4．9）；与工作时间≤8h者相比，工作时间9—10和〉10h者Ms患病风险升高，其OR值分别为8．7（3．2—23．7）和4．5（1．6-12．3）；与无中度运动者相比，有中度运动者Ms患病风险降低，其OR=0．7（O．5—0．9）；与睡眠时间〈7h者相比，睡眠时间≥8h者MS患病风险降低，其OR=0．6（0．4-0．9）；与生活或工作压力大／非常大者相比，生活或工作压力一般者MS患病风险降低，其OR值分别为0．7（0．6—1．O）和0．7（0．5-0．9），而生活或工作压力不大／没有者MS患病风险升高，其OR值分别为1．9（1．4-2．6）和1．9（1．3—2．6）。结论广东省就业流动人口MS患病率处于较高水平，可能影响MS患病率的可改变危险因素有吸烟、饮酒、工作强度、运动不足、睡眠不足和压力等，建议采取相应的干预措施降低就业流动人口的MS患病率。

关键词：流动人口代谢综合征流行病学因素分析统计学

A new cyclostellettamine from sponge Amphimedon compressa

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Chinese Chemical Letters 2007年第8期18卷 947-950页

作者： Nian jun xu xue Sun Xiao jun yan Key Laboratory of Marine Biotechnology Faculty of Life Science and Biotechnology Ningbo University Ningbo 315211 China

A new compound, 8,8＇-dienecyclostellettamine, was isolated from the marine sponge Amphimedon compressa. Its structure was elucidated by spectroscopic methods including 1D and 2D NMR, UV, IR, ESI-MS, MALDI-MS techniques. It is probably an important precursor of the manzamine alkoids, and also showed vigorous antibacterial activities.

关键词： Amphimedon compressa Antibacterial 8,8'-Dienecyclostellettamine

Deciphering fungal metabolon coupling tandem inverse-electrondemand Diels-Alder reaction and semipinacol rearrangement for the biosynthesis of spiro polycyclic alkaloids

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Science China Chemistry 2025年第01期 288-296页

作者： Shuai Liu Wen-Qiang xu Ying-Tong Di Man-Cheng Tang Ding-Kang Chen Ming-Ming Cao Yao-Wen Chang Hong-Yu Tang Chun-Mao Yuan jun-Bo yang Zhi-Li Zuo Han Guo Zi-Fei xu Ying Zeng Yun-Dong Wu Xiao-Jiang Hao Key Laboratory of Phytochemistry and Natural Medicines (Chinese Academy of Sciences) Kunming Institute of Botany Chinese Academy of Sciences University of Chinese Academy of Sciences Lab of Computational Chemistry and Drug Design State Key Laboratory of Chemical Oncogenomics Peking University Shenzhen Graduate School Shenzhen Bay Laboratory State Key Laboratory of Microbial Metabolism School of Life Sciences & Biotechnology Shanghai Jiao Tong University State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical University Molecular Biology Experimental Center Germplasm Bank of Wild Species in Southwest China Kunming Institute of Botany Chinese Academy of Sciences Yunnan Key Laboratory for Wild Plant Resources Kunming Institute of Botany Chinese Academy of Sciences Research Unit of Chemical Biology of Natural Anti-Virus Products Chinese Academy of Medical Sciences

In the intricate process of natural product biosynthesis, a metabolon can enhance metabolic flux by associating sequential enzymes. A fungal metabolon, comprising of flavin-dependent monooxygenase Spe F and P450 monooxygenase Spe G, is identified in the biosynthesis of spiro polycyclic alkaloids(+)-notoamide B and its diastereomer(+)-versicolamide B. Using notoamide E as a substance, Spe F/Spe G metabolon can control the stereoselectivity of its 2,3-epoxidation, followed by hydrogen atom ion at C-17 to generate reactive epoxide tau-m A with dienyl iminium unit. Subsequently,(+)-notoamide B and(+)-versicolamide B are produced via tandem nonenzymatic inverse-electron-demand Diels-Alder reaction and semipinacol rearrangement. This provides the first example of metabolon in the biosynthesis of spiro-prenylated indole alkaloids.

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