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新型风味素对养殖脊尾白虾海鲜风味的影响

水产学报 2005年第4期29卷 507-511页

作者：徐年军严小军徐继林徐善良宁波大学海洋生物工程重点实验室宁波大学海洋生物工程重点实验室浙江宁波315211

运用感官分析和GC/MS技术研究了两种新型海洋风味素对养殖脊尾白虾的感官特征和海鲜风味的影响,以及在暂养过程中的吸收规律。在脊尾白虾室内暂养的饲料中添加从海藻中提取的两种新型风味素DBP和TBP,经过一段时间的暂养后分别测定其体... 详细信息

运用感官分析和GC/MS技术研究了两种新型海洋风味素对养殖脊尾白虾的感官特征和海鲜风味的影响,以及在暂养过程中的吸收规律。在脊尾白虾室内暂养的饲料中添加从海藻中提取的两种新型风味素DBP和TBP,经过一段时间的暂养后分别测定其体内的风味素含量,并进行感官分析,对各个实验组的明度、色调、香味、风味、异味、滋味、味觉、弹性和嫩度等感官指标进行分析比较、打分,并对虾的色泽、嗅觉、味觉、触觉等感官特征进行整体的描述与评价。结果表明:脊尾白虾能通过饲料添加的途径吸收一定浓度的风味素,两种风味素在脊尾白虾体内的累积能力各不相同。在实验条件下,脊尾白虾肉中风味素TBP的最大累积量为754.5ng·g-1,而对DBP的最大累积量为172.2ng·g-1。感官分析表明,通过在暂养过程中添加适量的风味素TBP可提高脊尾白虾的总体口感和海鲜风味。在脊尾白虾肉中的TBP含量在162.6～451.8ng·g-1时,脊尾白虾具有最好的口感和海鲜味。

关键词：脊尾白虾风味素感官分析

海产品中溴酚类海洋风味素的气相色谱-质谱联用分析

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水产学报 2004年第1期28卷 100-105页

作者：徐继林严小军徐年军沈佳沈丽君宁波大学海洋生物工程重点实验室宁波大学海洋生物工程重点实验室浙江宁波 315211

建立了海产品中的溴酚类海洋风味素的毛细管气相色谱-质谱联用检测法。样品中溴酚类化合物在挥发油测定器中用乙酸乙酯通过循环蒸馏萃取,浓缩后用电子轰击源在特征离子碎片扫描检测模式下进行检测。结果表明,5种溴酚类化合物在SBP-50柱... 详细信息

建立了海产品中的溴酚类海洋风味素的毛细管气相色谱-质谱联用检测法。样品中溴酚类化合物在挥发油测定器中用乙酸乙酯通过循环蒸馏萃取,浓缩后用电子轰击源在特征离子碎片扫描检测模式下进行检测。结果表明,5种溴酚类化合物在SBP-50柱上得到良好的分离,色谱出峰尖锐,没有杂峰干扰。本方法在2.5～40 mg·L-1浓度范围内线性关系良好,最低检测限低于1ng·mL-1。当向25.00g样品中添加溴苯酚各2.0μg时,平均回收率分别达到90.45％（2-BP）、60.49％（4-BP）、85.79％（2,4-DBP）、84.98％（2,6-DBP）、90.80％（2,4,6-TBP）,标准相对偏差为1.37％～4.16％。对市场上销售的几种海洋经济动物测定,溴酚类风味素含量在5.40～31.38 ng·g-1范围内,而所测得的淡水青虾中溴酚类风味素含量只有0.18 ng·g-1。

关键词：海产品溴酚风味素气相色谱质谱联用

Pathogenesis, diagnosis, and treatment of epilepsy: electromagnetic stimulation-mediated neuromodulation therapy and new technologies

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Neural Regeneration Research 2025年第4期20卷 917-935页

作者： Dian Jiao Lai xu Zhen Gu Hua yan Dingding Shen Xiaosong Gu Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Key Laboratory of Advanced Drug Delivery Systems of Zhejiang Province College of Pharmaceutical SciencesZhejiang UniversityHangzhouZhejiang ProvinceChina Affiliated Hospital of Nantong University NantongJiangsu ProvinceChina

Epilepsy is a severe,relapsing,and multifactorial neurological *** regarding the accurate diagnosis,prognosis,and in-depth pathogenesis are crucial for the precise and effective treatment of *** pathogenesis of epilepsy is complex and involves alterations in variables such as gene expression,protein expression,ion channel activity,energy metabolites,and gut microbiota *** results are lacking for conventional treatments for *** resection of lesions,drug therapy,and non-drug interventions are mainly used in clinical practice to treat pain associated with ***-pharmacological treatments,such as a ketogenic diet,gene therapy for nerve regeneration,and neural regulation,are currently areas of research *** review provides a comprehensive overview of the pathogenesis,diagnostic methods,and treatments of *** also elaborates on the theoretical basis,treatment modes,and effects of invasive nerve stimulation in neurotherapy,including percutaneous vagus nerve stimulation,deep brain electrical stimulation,repetitive nerve electrical stimulation,in addition to non-invasive transcranial magnetic stimulation and transcranial direct current *** studies have shown that electromagnetic stimulation-mediated neuromodulation therapy can markedly improve neurological function and reduce the frequency of epileptic ***,many new technologies for the diagnosis and treatment of epilepsy are being ***,current research is mainly focused on analyzing patients’clinical manifestations and exploring relevant diagnostic and treatment methods to study the pathogenesis at a molecular level,which has led to a lack of consensus regarding the mechanisms related to the disease.

关键词： diagnosis drug treatment electroencephalography epilepsy monitoring epilepsy nerve regeneration neurostimulation non-drug interventions pathogenesis prediction

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在校大学生孝道观的分析与研究

新余学院学报 2017年第2期22卷 131-133页

作者：张岩徐俊安徽农业大学人文社会科学学院安徽合肥230036

通过对合肥市两所大学214名在校大学生发放《在校大学生对孝道的认识》自制问卷进行调查,采用统计描述方法对相关变量进行分析。选取主要个体特征变量进行卡方检验来检测不同群体之间的差异性。调查结果显示,女生比男生更愿意留在父母身... 详细信息

通过对合肥市两所大学214名在校大学生发放《在校大学生对孝道的认识》自制问卷进行调查,采用统计描述方法对相关变量进行分析。选取主要个体特征变量进行卡方检验来检测不同群体之间的差异性。调查结果显示,女生比男生更愿意留在父母身边,独生子比非独生子对父母的依赖性更强,城市大学生和农村大学生都认为孝敬父母时,精神层面要高于物质层面。对策和建议:加深大学生对传统文化的认知程度,加强对大学生的孝道教育,引导大学生树立正确的孝道观,完善自我,提高素质,更新观念,孝敬父母。

关键词：大学生孝道观问题建议

Non-coding RNAs in acute ischemic stroke:from brain to periphery

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Neural Regeneration Research 2025年第1期20卷 116-129页

作者： Shuo Li Zhaohan xu Shiyao Zhang Huiling Sun Xiaodan Qin Lin Zhu Teng Jiang junshan Zhou Fuling yan Qiwen Deng Department of Neurology Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina Department of Neurology Zhongda HospitalSchool of MedicineSoutheast UniversityNanjingJiangsu ProvinceChina General Clinical Research Center Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina

Acute ischemic stroke is a clinical emergency and a condition with high morbidity,mortality,and *** predictive,diagnostic,and prognostic biomarkers and effective therapeutic targets for acute ischemic stroke remain *** innovations in high-throughput gene sequencing analysis,many aberrantly expressed non-coding RNAs(ncRNAs)in the brain and peripheral blood after acute ischemic stroke have been found in clinical samples and experimental *** expressed ncRNAs in the post-stroke brain were demonstrated to play vital roles in pathological processes,leading to neuroprotection or deterioration,thus ncRNAs can serve as therapeutic targets in acute ischemic ***,distinctly expressed ncRNAs in the peripheral blood can be used as biomarkers for acute ischemic stroke prediction,diagnosis,and *** particular,ncRNAs in peripheral immune cells were recently shown to be involved in the peripheral and brain immune response after acute ischemic *** this review,we consolidate the latest progress of research into the roles of ncRNAs(microRNAs,long ncRNAs,and circular RNAs)in the pathological processes of acute ischemic stroke–induced brain damage,as well as the potential of these ncRNAs to act as biomarkers for acute ischemic stroke prediction,diagnosis,and *** from this review will provide novel ideas for the clinical application of ncRNAs in acute ischemic stroke.

关键词： acute ischemic stroke apoptosis blood–brain barrier damage circular RNAs excitatory toxicity long non-coding RNAs microRNAs neuroinflammation non-coding RNAs oxidative stress

Recombinant chitinase-3-like protein 1 alleviates learning and memory impairments via M2 microglia polarization in postoperative cognitive dysfunction mice

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Neural Regeneration Research 2025年第9期20卷 2727-2736页

作者： Yujia Liu xue Han yan Su Yiming Zhou Minhui xu Jiyan xu Zhengliang Ma Xiaoping Gu Tianjiao Xia Department of Anesthesiology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina Medical School Nanjing UniversityNanjingJiangsu ProvinceChina Jiangsu Key Laboratory of Molecular Medicine Nanjing UniversityNanjingJiangsu ProvinceChina State Key Laboratory of Pharmaceutical Biotechnology Nanjing UniversityNanjingJiangsu ProvinceChina Department of Anesthesiology Zhongshan HospitalFudan UniversityShanghaiChina

Postoperative cognitive dysfunction is a seve re complication of the central nervous system that occurs after anesthesia and surgery,and has received attention for its high incidence and effect on the quality of life of *** date,there are no viable treatment options for postoperative cognitive *** identification of postoperative cognitive dysfunction hub genes could provide new research directions and therapeutic targets for future *** identify the signaling mechanisms contributing to postoperative cognitive dysfunction,we first conducted Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses of the Gene Expression Omnibus GSE95426 dataset,which consists of mRNAs and long non-coding RNAs differentially expressed in mouse hippocampus3 days after tibial *** dataset was enriched in genes associated with the biological process"regulation of immune cells,"of which Chill was identified as a hub ***,we investigated the contribution of chitinase-3-like protein 1 protein expression changes to postoperative cognitive dysfunction in the mouse model of tibial fractu re *** were intraperitoneally injected with vehicle or recombinant chitinase-3-like protein 124 hours post-surgery,and the injection groups were compared with untreated control mice for learning and memory capacities using the Y-maze and fear conditioning *** addition,protein expression levels of proinflammatory factors(interleukin-1βand inducible nitric oxide synthase),M2-type macrophage markers(CD206 and arginase-1),and cognition-related proteins(brain-derived neurotropic factor and phosphorylated NMDA receptor subunit NR2B)were measured in hippocampus by western *** with recombinant chitinase-3-like protein 1 prevented surgery-induced cognitive impairment,downregulated interleukin-1βand nducible nitric oxide synthase expression,and upregulated CD206,arginase-1,pNR2B,and brain-derived neurotropic factor expr

关键词： Chil1 hippocampus learning and memory M2 microglia neuroinflammation postoperative cognitive dysfunction(POCD) recombinant CHI3L1

Establishing a new testing protocol of the electrochemical stability window for electric double-layer capacitors

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Science China Chemistry 2025年第01期 217-225页

作者： Ruilin Hou Xiaoxi Zhao Tingting Liang Qingyun Dou Shan xu Xingbin yan School of Materials Science and Engineering Sun Yat-sen University Laboratory of Clean Energy Chemistry and Materials Lanzhou Institute of Chemical Physics Chinese Academy of Sciences College of Engineering and Applied Sciences Nanjing University Center of Industrial Analysis and Testing Guangdong Academy of Science

The electrochemical stability window(ESW) is crucial for determining the energy density of electric double-layer capacitors(EDLCs). However, current ESW testing protocols of EDLCs are strongly affected by artificial factors, thereby leading to unreliable result. To solve this problem, we first identify the key shortcomings of the traditional protocols by analyzing their test principles. Subsequently, taking an aqueous carbon-based EDLC as an example, we design a side reaction descriptor to represent the response difference in the charging capacitance to side reactions between the cyclic voltammetry and galvanostatic chargedischarge methods. With the aid of this descriptor, we propose a new ESW testing protocol, which is not only able to completely avoid the adverse influence of subjective factors but also fully consider the operating condition limitations. The protocol can be extended from the single electrode to the full device. This work proposes a more rigorous definition of ESW and provides a reliable protocol for evaluating the ESW of EDLCs.

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织物结构对其干热传递性能的影响

苏州丝绸工学院学报 1990年第3期10卷 50-59页

作者：陈雁续骏苏州丝绸工学院纺织品设计教研室苏州丝绸工学院丝绸85(1)班

本文在分析了织物传热机理的基础上,探讨了有关组织结构的参数对织物传热的影响以及能反映这些参数影响作用的综合评价指标.并以七种涤纶织物为试样,进行有关结构参数和传热性能的测试与分析,为建立织物结构与传热极能的关系进行了初步... 详细信息

本文在分析了织物传热机理的基础上,探讨了有关组织结构的参数对织物传热的影响以及能反映这些参数影响作用的综合评价指标.并以七种涤纶织物为试样,进行有关结构参数和传热性能的测试与分析,为建立织物结构与传热极能的关系进行了初步的工作.

关键词：织物结构织物性能热传递

常规超声与超声弹性成像联合诊断乳腺BI-RADS 4级肿块的价值

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中国现代医学杂志 2015年第22期25卷 86-88页

作者：许东峰何燕许君燕朱帆周凤洁江苏南京中医药大学附属昆山市中医医院超声科江苏昆山215300

目的探讨常规超声与超声弹性成像联合诊断乳腺BI-RADS 4级乳腺肿块的价值。方法回顾分析104例106个BI-RADS 4级乳腺肿块的常规超声和超声弹性成像检查结果,以及常规超声与超声弹性成像联合诊断检查结果,结果与手术病理对照。结果常规超... 详细信息

目的探讨常规超声与超声弹性成像联合诊断乳腺BI-RADS 4级乳腺肿块的价值。方法回顾分析104例106个BI-RADS 4级乳腺肿块的常规超声和超声弹性成像检查结果,以及常规超声与超声弹性成像联合诊断检查结果,结果与手术病理对照。结果常规超声与超声弹性成像联合诊断BI-RADS 4级乳腺肿块,诊断价值优于单独应用常规超声与超声弹性成像,差异有统计学意义(P<0.05)。结论常规超声结合超声弹性成像有助于提高常规超声诊断乳腺BI-RADS 4级肿块鉴别诊断能力。

关键词：超声弹性成像乳腺肿瘤