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ERAS理念下机器人辅助非体外循环冠状动脉旁路移植术精准护理模式的应用效果

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机器人外科学杂志（中英文） 2024年第3期5卷 406-411页

作者：武鑫闫杰立邢台市人民医院心脏外科河北邢台054000

目的:探究基于加速康复外科(ERAS)理念下机器人辅助非体外循环冠状动脉旁路移植术精准护理模式的应用效果。方法:选取2021年7月—2023年8月在邢台市人民医院心脏外科接受机器人辅助非体外循环冠状动脉旁路移植术的70例患者。采用随机数... 详细信息

目的:探究基于加速康复外科(ERAS)理念下机器人辅助非体外循环冠状动脉旁路移植术精准护理模式的应用效果。方法:选取2021年7月—2023年8月在邢台市人民医院心脏外科接受机器人辅助非体外循环冠状动脉旁路移植术的70例患者。采用随机数字表法将其分为研究组(n=35,精准护理)和对照组(n=35,常规护理)。观察和比较两组患者的禁饮、禁食情况、拔管时间、术后恢复情况、心理状态、不良心血管事件发生情况和护理满意度。结果:研究组在术前禁食、禁饮时间、气管插管、尿管、纵隔引流管、心包积液引流管、胸管拔管时间、首次进水时间、进食时间、排便时间、下床时间、心率恢复正常时间、住院时间、导管引流量、SAS评分、SDS评分及术后不良心血管事件发生率等方面均优于对照组(P<0.05);研究组的6MWD长于对照组(P<0.05);研究组护理总满意度明显高于对照组(P<0.05)。结论:与传统护理干预模式相比,基于ERAS理念指导下的精准护理模式在机器人辅助非体外循环冠状动脉旁路移植术中有利于促进患者快速康复,在有效控制不良心血管事件的同时,还能够提升护理满意度,值得临床应用和推广。

关键词：加速康复外科机器人辅助手术非体外循环冠状动脉旁路移植术精准护理

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CYP1A1,GSTs and mEH polymorphisms and susceptibility to esophageal carcinoma:Study of population from a high-incidence area in north China

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World Journal of Gastroenterology 2003年第7期9卷 1394-1397页

作者： Jian-XiangZhou yan-jieli Ji-XueLi Li-DongWang ShuZheng BinLiu LaboratoryforCancerResearch CollegeofMedicineZhengzhouUniversityZhengzhou450052HenanProvinceChina CancerInstitute ZhejiangUniversityHangzhou310009ZhejiangProvinceChinaandLaboratoryforCancerResearchCollegeofMedicineZhengzhouUniversityZhengzhou450052HenanProvinceChina CancerInstitute ZhejiangUniversityHangzhou310009ZhejiangProvinceChina DepartmentofGastroenterology TongrenHospitalCapitalMedicalUniversityBeijing100013China

AIM: To characterize cytochrome P4501A1 (CYPIA1), glutathione S-transferases (GSTs) and microsomal epoxide hydrolase (mEH) polymorphisms in Chinese esophageal cancer patients. METHODS: Multiplex polymerase chain reaction (PCR) and PCR based restriction fragment length polymorphisms (PCRRFLP) were used to detect polymorphism changes of CYP,GSTs and mEH on esophageal cancerous and precancerous lesions as well as in case control group. All the examination samples were obtained from Linzhou (formerly Linxian), Henan Province, the highest incidence area for esophageal. RESULTS: The frequency of CYP1A1 3'' polymorphism in case control group (26/38, 68 %) was significantly higher than in esophageal squamous cell carcinoma^roup (ESCC) (29/62, 47 %) (P<0.05). A significant difference in the incidence of mEH slow allele variant was observed between case control group (15/38, 39 %) and esophageal dysplasiagroup (22/32, 69 %) or ESCC group (39/62, 63 %) (P<0.05). However, no significant difference was observed among different groups in the polymorphisms of CYPIA1 exon 7, GSTM1, GSTT1, GSTP1 and mEH fast allele. CONCLUSION: The present results suggest that CYPIA1 3'' polymorphism may be one of the promising protectivef actors and its wild gene type may be an indicator for higher susceptibility to esophageal cancer, mEH slow allele variant,associated with the progression of esophageal precancerous lesions, may conthbute to the high susceptibility to esophageal carcinoma.

关键词： CYPIA1 GSTs mEH 基因多态性食道癌聚合酶链反应

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我国环境养生旅游发展探讨

安徽农业科学 2011年第1期39卷 377-379页

作者：颜节礼江南大学商学院江苏无锡214122

介绍了环境养生旅游的概念、资源条件,并针对我国环境养生旅游发展状况展开分析,提出已取得的成就和存在问题,最终提出解决方案。

关键词：中国环境养生旅游发展探讨

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苏南国家级非物质文化遗产文化旅游开发潜力研究

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地域研究与开发 2013年第5期32卷 157-162页

作者：吴媛媛颜节礼江南大学商学院工商管理系江苏无锡214122

以苏州、无锡、常州、镇江、南京的3批国家级非物质文化遗产为研究对象,构建针对非遗文化旅游开发潜力的三级指标评价体系,通过专家评估法与层次分析法测算指标权重,对各评价因子进行模糊打分得到各市的综合评价结果。五市的非物质文化... 详细信息

以苏州、无锡、常州、镇江、南京的3批国家级非物质文化遗产为研究对象,构建针对非遗文化旅游开发潜力的三级指标评价体系,通过专家评估法与层次分析法测算指标权重,对各评价因子进行模糊打分得到各市的综合评价结果。五市的非物质文化遗产的文化旅游潜力集中于Ⅱ、Ⅲ等级,总体品位突出,开发潜力大。南京的民俗类、苏州传统美术与表演艺术类优势明显,无锡、常州、镇江三市整体相对薄弱。除少数项目与旅游有较好的结合,大多项目囿于专业市场,但有较大的文化旅游开发空间。最后结合具体项目分类别提出非遗文化旅游的开发策略。

关键词：非物质文化遗产文化旅游层次分析法开发潜力苏南

Standford B型主动脉夹层患者的围术期护理对策分析

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中国卫生标准管理 2020年第24期11卷 162-164页

作者：闫杰立河北省邢台市人民医院心脏外科河北邢台054000

目的探讨主动脉腔内覆膜支架治疗Standford B型主动脉夹层患者的围术期护理对策。方法将医院于2018年10月—2019年10月收治的100例Standford B型主动脉夹层患者作为研究对象,随机进行分组,其中对照组与研究组各50例。两组患者均接受主... 详细信息

目的探讨主动脉腔内覆膜支架治疗Standford B型主动脉夹层患者的围术期护理对策。方法将医院于2018年10月—2019年10月收治的100例Standford B型主动脉夹层患者作为研究对象,随机进行分组,其中对照组与研究组各50例。两组患者均接受主动脉腔内覆膜支架治疗,在此基础上,对照组患者实施常规护理对策,研究组患者实施围术期全程护理对策。比较两组患者的疼痛评分、并发症发生率。结果护理后,研究组的疼痛评分(4.61±0.90)分明显低于对照组(5.37±0.98)分,研究组的的并发症发生率(4.00%)明显低于对照组(16.00%),比较有统计学意义(P<0.05)。结论实施围术期全程护理对策有助于提高Standford B型主动脉夹层患者行主动脉腔内覆膜支架治疗的效果,改善患者的疼痛感,降低了并发症发生率,具有临床应用价值。

关键词：主动脉腔内覆膜支架 Standford B型主动脉夹层患者围术期护理疼痛评分并发症

Statistical inference methods and applications of outcome-dependent sampling designs under generalized linear models

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Science China Mathematics 2017年第7期60卷 1219-1238页

作者： yan Shu DING jieli LIU yanyan School of Mathematics and Statistics Wuhan University Wuhan 430072 China

A cost-effective sampling design is desirable in large cohort studies with a limited budget due to the high cost of measurements of primary exposure *** outcome-dependent sampling(ODS) designs enrich the observed sample by oversampling the regions of the underlying population that convey the most information about the exposure-response *** generalized linear models(GLMs) are widely used in many fields,however,much less developments have been done with the GLMs for data from the ODS *** study how to fit the GLMs to data obtained by the original ODS design and the two-phase ODS design,*** asymptotic properties of the proposed estimators are derived.A series of simulations are conducted to assess the finite-sample performance of the proposed *** to a Wilms tumor study and an air quality study demonstrate the practicability of the proposed methods.

关键词： biased-sampling two-phase design generalized linear models empirical likelihood

Associations of sleeping patterns and isotemporal substitution of other behavior with the prevalence of CKD in Chinese adults

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Frontiers of Medicine 2024年第2期18卷 303-314页

作者： Yi Ding Xiaoli Xu Zhuojun Xin Qiuyu Cao Jiaojiao Huang Xianglin Wu yanan Huo Qin Wan Yingfen Qin Ruying Hu Lixin Shi Qing Su Xuefeng Yu Li yan Guijun Qin Xulei Tang Gang Chen Min Xu Tiange Wang Zhiyun Zhao Zhengnan Gao Guixia Wang Feixia Shen Zuojie Luo Li Chen Qiang Li Zhen Ye Yinfei Zhang Chao Liu Youmin Wang Tao yang Huacong Deng Lulu Chen Tianshu Zeng Jiajun Zhao Yiming Mu Shengli Wu Yuhong Chen jieli Lu Weiqing Wang Guang Ning Yu Xu Yufang Bi Mian Li Department of Endocrine and Metabolic Diseases Shanghai Institute of Endocrine and Metabolic DiseasesRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai200025China Shanghai National Clinical Research Center for Metabolic Diseases Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of ChinaShanghai Key Laboratory for Endocrine TumorState Key Laboratory of Medical GenomicsRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai200025China Jiangxi Provincial People’s Hospital Affiliated to Nanchang UniversityNanchang330000China Department of Endocrinology The Affiliated Hospital of Southwest Medical UniversityLuzhou646000China Department of Endocrinology The First Affiliated Hospital of Guangxi Medical UniversityNanning530000China Zhejiang Provincial Center for Disease Control and Prevention Hangzhou310000China Department of Endocrinology Affiliated Hospital of Guiyang Medical UniversityGuiyang550000China Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai200000China Tongji Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan430000China Sun Yat-sen Memorial Hospital Sun Yat-sen UniversityGuangzhou510000China Department of Endocrinology The First Affiliated Hospital of Zhengzhou UniversityZhengzhou450000China Department of Endocrinology The First Hospital of Lanzhou UniversityLanzhou730000China Fujian Provincial Hospital Fujian Medical UniversityFuzhou350000China Dalian Municipal Central Hospital Affiliated of Dalian Medical UniversityDalian116000China Department of Endocrinology The First Hospital of Jilin UniversityChangchun130000China Department of Endocrinology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou325000China Qilu Hospital of Shandong University Jinan250000China Department of Endocrinology The Second Affiliated Hospital of Harbin Medical UniversityHarbin150000China Department of Endocrinology Cen

Studies have found a U-shaped relationship between sleep duration and chronic kidney disease(CKD)risk,but limited research evaluated the association of reallocating excessive sleep to other behavior with *** included 104538 participants from the nationwide cohort of the Risk Evaluation of Cancers in Chinese Diabetic Individuals:A Longitudinal Study,with self-reported time of daily-life *** isotemporal substitution models,we found that substituting 1 h of sleeping with sitting,walking,or moderate-to-vigorous physical activity was associated with a lower CKD ***-time physical activity displacement was associated with a greater prevalence reduction than occupational physical activity in working *** stratified analysis,a lower CKD prevalence related to substitution toward physical activity was found in long *** pronounced correlations were observed in long sleepers with diabetes than in those with prediabetes,and they benefited from other behavior substitutions toward a more active *** U-shaped association between sleep duration and CKD prevalence implied the potential effects of insufficient and excessive sleep on the kidneys,in which the pernicious link with oversleep could be reversed by time reallocation to physical *** divergence in the predicted effect on CKD following time reallocation to behavior of different domains and intensities and in subpopulations with diverse metabolic statuses underlined the importance of optimizing sleeping patterns and adjusting integral behavioral composition.

关键词： sleep physical activity chronic kidney disease isotemporal substitution behavioral pattern

广西南宁一次“龙舟水”暴雨空报事件对流生消成因分析

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气象 2024年第8期50卷 941-952页

作者：周琰翟丽萍张丁丁樊盛黄卓帆李渝平李紫甜潘杰丽黄增俊南宁市气象局南宁530029 广西壮族自治区气象台南宁530022 广西南宁市邕宁区气象局邕宁530200

2022年6月13日,广西出现大范围暴雨过程,而南宁市区一带暴雨空报;雷达回波在南宁市区北侧衰减、东侧强度维持、南侧新生发展,过程演变复杂。文章采用常规观测资料及ERA5再分析资料,对此次过程中对流生消演变成因进行分析。结果表明:此... 详细信息

2022年6月13日,广西出现大范围暴雨过程,而南宁市区一带暴雨空报;雷达回波在南宁市区北侧衰减、东侧强度维持、南侧新生发展,过程演变复杂。文章采用常规观测资料及ERA5再分析资料,对此次过程中对流生消演变成因进行分析。结果表明:此次过程为典型广西前汛期强降雨环流形势及环境背景;然而受天气尺度冷平流及风暴冷池共同影响,冷空气快速移过南宁市区,北侧风暴出流边界远离母体,风暴前侧低层水汽输送偏东,热力、动力条件均较差,导致回波衰减消散;南宁市区东侧风暴在推进过程中出流边界紧贴母体,风暴前侧低层维持西南急流,沿出流边界不断有对流触发,风暴得以加强或维持;南侧低层高温高湿环境形成,有利于对流有效位能重建或增强。最后建立了此次过程对流生消演变机理概念模型,并通过分析冷池、出流边界、环境条件等要素演变,可对短时临近预报进行补充订正。

关键词：暴雨空报对流生消冷平流冷池出流边界

CDCA3基因表达对膀胱癌患者临床病理和预后的影响

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华南国防医学杂志 2018年第3期32卷 157-160页

作者：何恒晶李洁莉晏鑫李晓凤李胜周强徐畅武汉大学中南医院生物样本库湖北武汉430071 武汉大学中南医院泌尿外科湖北武汉430071 四川大学华西医院中国循证医学中心

目的研究细胞分裂周期相关因子3(cell division cycle associated protein 3,CDCA3)基因表达对膀胱癌患者临床病理特征和预后的影响。方法从基因表达综合数据库(gene expression omnibus,GEO)下载膀胱癌样本表达谱资料GSE13507及其对应... 详细信息

目的研究细胞分裂周期相关因子3(cell division cycle associated protein 3,CDCA3)基因表达对膀胱癌患者临床病理特征和预后的影响。方法从基因表达综合数据库(gene expression omnibus,GEO)下载膀胱癌样本表达谱资料GSE13507及其对应的临床信息。采用t检验明确CDCA3在膀胱癌组织和正常组织中的表达差异,χ2检验分析CDCA3基因表达与膀胱癌患者临床病理特征的相关性,Log-rank法进行生存分析比较;并利用基因集富集分析(gene set enrichment analysis,GSEA)方法,预测膀胱癌细胞受CDCA3调控的相关通路。结果 CDCA3在膀胱癌细胞中高表达;在癌细胞的肌层浸润性、T分期、N分期及肿瘤分级方面,CDCA3高表达的膀胱癌患者明显较低表达患者严重;CDCA3高表达患者的肿瘤特异性生存期及总生存期显著低于低表达患者。GSEA结果表明,CDCA3可能通过调节精子发生、G2M检查点、mTOR信号通路、E2F信号通路、MYC信号通路、未折叠蛋白反应、胆固醇平衡、糖酵解反应、细胞的有丝分裂纺锤体等对膀胱癌的发生发展产生影响。结论 CDCA3可能成为潜在的判断膀胱癌患者预后的标志物和治疗肿瘤的靶点。

关键词：细胞分裂周期相关因子3 膀胱癌细胞病理预后