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Magnetic resonance imaging combined with serum endolipin and galactagoglobin-3 to diagnose cerebral infarction in the elderly with diabetes mellitus

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World Journal of Diabetes 2024年第7期15卷 1509-1517页

作者： yan-hui zhang Dong Liang Magnetic Resonance Imaging Room Tianjin Huanhu HospitalTianjin 300350China Department of Endocrinology Tianjin First Central HospitalTianjin 300190China

BACKGROUND Magnetic resonance imaging(MRI)combined with serum endothelin and galactagoglobin-3(Gal-3)can improve the clinical diagnosis of diabetes mellitus complicated with cerebral *** To analyze the clinical value of MRI combined with serum endolipin and Gal-3 for the diagnosis of cerebral infarction in the elderly with diabetes *** One hundred and fifty patients with acute cerebral infarction hospitalized between January 2021 and December 2023 were divided into two groups according to comorbid diabetes mellitus,including 62 and 88 cases in the diabetic and nondiabetic cerebral infarction *** samples were collected to detect the expression of serum endolipoxins,and Gal-3,and cranial MRI was performed at *** between the two groups were compared to analyze the diagnostic value of these *** Serum endolipin and Gal-3 expression were higher in the diabetic cerebral infarction group(P<0.05).The arterial wall area,vessel area,normalized wall index,and lumen stenosis rate were higher in the diabetic cerebral infarction group,while the rate of arterial lumen moderate and severe stenosis was 48.39% higher(36.36%,P<0.05).The percentage of large(29.03%)and multiple infarcts(33.87%)in the diabetic cerebral infarction group was higher(13.64% and 20.45%),and the incidence rate of lacunar infarcts was lower(37.10%vs 65.91%)(P<0.05).The total incidence of arterial plaque in patients in the diabetic cerebral infarction group was 96.77% higher(69.32%),while the incidence of necrotic lipid core plaque was 58.06%higher(26.14%)(P<0.05).Receiver operating characteristic curve analysis was performed to assess the diagnosis utility of these *** in combination with serum endoglin and Gal-3 had the highest area under the curve,the Yoden index,sensitivity and specificity(P<0.05).CONCLUSION The expression of serum endolipin and Gal-3 in elderly patients with diabetes mellitus with cerebral infarction showed an eleva

关键词： Endolipin Galectin-3 Magnetic resonance imaging Elderly Diabetes mellitus Cerebral infarction

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Mossbauer spectroscopy studies on the particle size distribution effect of Fe–B–P amorphous alloy on the microwave absorption properties

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Nuclear Science and Techniques 2020年第3期31卷 10-19页

作者： Yu-Hua Lv yan-hui zhang Jian zhang Bin Li School of Materials Science and Engineering Key Laboratory for Anisotropy and Texture of MaterialsMinistry of EducationNortheastern UniversityShenyang 110819China State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819China Institute of Advanced Magnetic Materials Hangzhou Dianzi UniversityHangzhou 310012China School of Life Sciences Huzhou UniversityHuzhou 313000China

An Fe-based nanocrystalline alloy powder is important for application in microwave absorption,and the particle size has a critical impact on the electromagnetic microwave ***,it is necessary to study further the effects of the particle size on such parameters and improve the microwave absorption performance of Febased nanocrystalline *** this study,Fe-B-P particles were prepared through a synthetic approach consisting of an aqueous chemical reduction and a ball milling *** investigated the effects of ball milling on the microstructure and electromagnetic properties of Fe-B-P *** experimental results indicate that the Fe-B-P particles synthesized through an aqueous chemical reduction are amorphous ***-B-P particles with an original particle size of 200-1200 nm can be milled into an irregular shape with the size reduced to\500 nm after 0.5 h of ball milling,and subsequently,the particles become smaller with increases in the milling time,with traces of Fe2O3 generated on the particle *** results of the Mo¨ssbauer spectra show that a portion of the small particles demonstrate a superparamagnetic *** volume proportions of the superparamagnetic component increase from 13.1 to 15.8%as the treatment time *** measured the permittivity and permeability spectra of Fe-B-P particles within the frequency range of 2-18 *** reflection loss(RL)is-10 dB for an absorber thickness of 1.7-5.0 *** RL is-20 dB for an absorber thickness of 1.9-2.7 *** microwave absorption properties of samples with the same thickness are improved with an increase in the treatment time and are shifted to a higher frequency,which will broaden the bandwidth of the absorption as well.

关键词： Fe-B-P particles Mossbauer spectroscopy Microwave absorber properties

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A new access scheme in OFDMA systems

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The Journal of China Universities of Posts and Telecommunications 2006年第3期13卷 29-33页

作者： GU Xueolin yan Wei TIAN hui zhang Ping Wireless Technology Innovation (WTI) Institute Beijing University of Postsand Telecommunications Beijing 100876 China

This article presents a dynamic random access scheme for orthogonal frequency division multiple access （OFDMA） systems. The key features of the proposed scheme are it is a combination of both the distributed and the centralized schemes, it can accommodate several delay sensitivity classes, and it can adjust the number of random access channels in a media access control （MAC） frame and the access probability according to the outcome of Mobile Terminals access attempts in previous MAC frames. For floating populated packet-based networks, the proposed scheme possibly leads to high average user satisfaction.

关键词： random access scheme RACH OFDMA dynamicaccess probability

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Electrochemical Performance of Solid Polymer Electrolyte PEO_(20)-LiTf-Urea_(1.5)

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Chemical Research in Chinese Universities 2011年第3期27卷 478-481页

作者： zhang Ding yan hui zhang Huan Q1 Lu Beijing National Laboratory for Molecular Sciences Institute of Applied Chemistry College of Chemistry and Molecular Engineering Peking University Beijing 100871 P~ R. China

A new solid polymer electrolyte PEO20-LiTf-Urea1.5 was prepared by solution casting technique. The energy of frontier orbitals for the components of the electrolyte was predicted by quantum chemistry calculations, and TG stability and electrochemical features were measured. Urea exhibited a lower HOMO energy than PEO, implying its enhanced stability against electrochemical oxidation. Experimentally addition of urea increases the ionic conductivity, which guarantees conductivity requirement for lithium ion batteries. It also results in significant improved electrochemical stability with good thermal stability. Favorable lithium stripping/plating performance is yielded, and it confirms the good stability of the solid electrolyte interphase for the PEO20-LiTf-Urea1.5 system.

关键词： Solid polymer electrolyte Urea Solution-casting technique

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Crack analysis in Ti-6Al-4V alloy produced by selective laser melting

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Tungsten 2021年第3期3卷 361-367页

作者： hui-yan zhang yan-hui Liu Zhi-Wei Li An-hui Xiong Ke Li Jia-Yun Fu School of Materials Engineering Shanghai University of Engineering ScienceShanghai 201620China

Quality and property control have become one of the critical problems for the metallic parts produced by selective laser *** this paper,the crack spontaneously formed in the Ti-6 Al-4 V alloy by selecting laser melting is *** crack is C-shape without branching in macro *** micro view,the crack originates from and propagates toward the selective laser melting(SLM)processing *** crack surface topography shows that the crack is typical dimple cleavage.A few heads of martensiticα’laths appear at the bottom of the *** the secondary crack nucleates and grows up near by the martensiticα’laths.A lot of spatters and cavities formed at the top surface of the SLM body and the residual stress accumulated in the SLM body is up to 640 MPa,which confirms that the SLM processing defects and the residual stress induced the origination and propagation of the *** research results indicate that preventing spatter and controlling residual stress are important to SLM processing.

关键词： Selecting laser melting Ti-6Al-4V Crack Processing defect Residual stress

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Charge doping effect on σ-π conjugated copolymers

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Science China Chemistry 2011年第6期54卷 975-984页

作者： yanG LuQing SHANG yan zhang hui SUN Miao LIU Bo zhang GuiLing Key Laboratory of Green Chemical Technology of College of Heilongjiang Province College of Chemical and Environmental Engineering Harbin University of Science and Technology Harbin 150080 China

The charge-doping effect on the geometric and the electronic structures of organosilicon oligomers nSix(C=C)+y has been studied using density functional theory. Charge-doping can significantly lower the excitation energies. Interchain hole hopping mainly occurs between the π-conjugated units. A doped nSix(C=C)+y oligomer can undergo a structural rearrangement. The simulated UV/vis absorption peak of the rearranged structure is located at higher energy than the non-rearranged one. The hole transfer rate is significantly decreased if a doped molecule undergoes a rearrangement. These results offer a basis to explain previously observed experimental phenomena.

关键词： organosilicon oligomers theoretical calculation charge-doping

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Influence of pH on short-cut denitrifying phosphorus removal

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Water Science and Engineering 2018年第1期11卷 17-22页

作者： Wei Li hui-yan zhang hui-zhi Sun Fei Zeng Yu-nan Gao Lei Zhu School of Municipal and Environmental Engineering Shenyang Jianzhu UniversityShenyang 110168China Shenyang Academy of Environmental Sciences Shenyang 110167China

Through a series of experiments using denitrifying phosphorus-accumulating sludge in sequencing batch reactors （SBRs）, the variations of the intracellular polymers during the anaerobic phosphorus release process at different pH values were compared, the probable reasons for different performances of phosphorus removal were examined, and system operations in a typical cycle were investigated. The results show that the phosphorus removal rate was positively correlated with pH values in a range of 6.5-8.5. When the pH value was 8.0, the anaerobic phosphorus release rate and anoxic phosphorus uptake rate of the activated sludge were 20.95 mg/（g, h） and 23.29 mg/（g, h）, respectively; the mass fraction of poly-13-hydroxybutyrate （PHB） increased to 62.87 mg/g under anaerobic conditions; the mass fraction of polyphosphate was 92.67 mg/g under anoxic conditions; and the effluent concentration of total phosphorus （TP） was 1.47 mg/L. With the increase of pH, the mass fraction of acetic acid and PHB also increased, and the absorption rate of acetic acid was equal to the disintegration rate of polyphosphate. When the pH value was above 8.0, biological phosphorus removal was achieved by chemical phosphorus precipitation, and the phosphorus removal rate decreased.

关键词： Denitrifying phosphorus removal pH Removal rate PHB

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Serum lipids and other risk factors for diabetic retinopathy in Chinese type 2 diabetic patients

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第5期14卷 392-399页

作者： hui-yan zhang Jian-yong WANG Gui-shuang YING Li-ping SHEN Zhe zhang Hangzhou Vocational & Technical College Department of Ophthalmology the First Affiliated HospitalSchool of MedicineZhejiang University Center for Preventive Ophthalmology and Biostatistics Department of OphthalmologyPerelman School of MedicineUniversity of Pennsylvania Department of Endocrinology the First Affiliated HospitalSchool of MedicineZhejiang University

Objective: To investigate the association of serum lipids and other risk factors with diabetic retinopathy (DR) in Chinese type 2 diabetic patients. Methods: Five hundred and twenty-three type 2 diabetic patients underwent ophthalmic examination by experienced retinal specialists to assess their DR. Serum lipids, including triglycerides, total cholesterol, high density lipoprotein cholesterol (HDLC), and low density lipoprotein cholesterol (LDLC), were measured using Roche automated clinical chemistry analyzers. The concentration of very low density lipoprotein cholesterol (VLDLC) was calculated based on total cholesterol, HDLC and LDLC. Hyperlipidemia was defined as a total cholesterol concentration of 6.2 mmol/L or higher or the use of lipid-lowering medications. The association of risk factors with any DR or proliferative diabetic retinopathy (PDR) was assessed using the odds ratio (OR) and its 95% confidence interval (CI), calculated from logistic regression models. Results: In multivariate logistic regression models, hyperlipidemia (OR=2.39, 95% CI: 1.02-5.66), higher VLDLC (OR=1.59, 95% CI: 1.14-2.23), and higher triglyceride (OR=1.18, 95% CI: 1.03-1.37) were associated with increased risk of DR. A longer diabetic duration was associated with increased risk of DR (P<0.0001) and PDR (P=0.002) in a dose-response manner. Higher systolic blood pressure (P=0.02) and higher serum creatinine (P=0.01) were independently associated with increased risk of DR, and female gender was associated with increased risk of PDR (P=0.03). Conclusions: Among Chinese type 2 diabetic patients, hyperlipidemia, higher VLDLC, and higher triglyceride were independently associated with increased risk of DR, suggesting control of serum lipids may decrease the risk of DR.

关键词： Diabetic retinopathy Serum lipids Risk factors

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Potential Anti-cancer Activity of Furanodiene

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Chinese Journal of Cancer Research 2009年第2期21卷 154-158页

作者： Zhen-zhen Ba yan-ping Zheng hui zhang Xiu-yan Sun Dong-hai Lin School of Pharmaceutical Science Yantai University Yantai 264005 China

Objective： To study the isolated from the essential oil VIVO anti-tumor activities of furanodiene of the rhizome of Curcuma wenyujin （C15H200）, a primary sesquiterpene compound YH Chen et C. Ling（Wen Ezhu）, in vitro and in Methods： In vitro MTT assay was used to further study the effects of time and dosage on anti-proliferation of furanodiene against the sensitive Hela, Hep-2, HL-60, U251 cells, based on the cytotoxic effects of furanodiene on 12 human malignant tumor cell lines with the essential oil of Wen Ezhn as control., and the half-inhibitory concentration （IC50） was observed. In vivo uterine cervix （U14） tumor cell was selected and the conventional assay method of anti-tumor activity was employed. Furanodiene liposome was administered intraperitoneally, and tumor-inhibitory rate, thymus and spleen indexes were observed. Results： The inhibitive effects on cell proliferation were shown in all of the twelve cell lines and the cytotoxic effects of furanodiene against Hela, Hep-2, HL-60, U251 cells were observed after 12 h of administration, the effect could last for at least 48 h in a dose dependent manner, and the IC50 values were 0.6, 1.7, 1.8, 7.0μg/ml, respectively. Furanodiene was also found to show inhibitive effects on the proliferation of uterine cervix （U14） tumor induced in mice. The tumor inhibition rates were 36.09% （40 mg/kg）, 41.55% （60 mg/kg）, 58.29% （80 mg/kg）, respectively. Conclusion： Furanodiene is one of primary anti-cancer active components in the essential oil of Wen Ezhu, and also a very effective agent against uterine cervix cancer, and has protection effect on the immune function.

关键词： Essential oil of Wen Ezhu Furanodiene Anti-cancer Uterine cervix cancer

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Geochronological and geochemical constraints on the petrogenesis and geodynamic process of Hemler,Vlinder,and Il'ichev seamount lavas in NW Pacific

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Science China Earth Sciences 2024年第6期67卷 1856-1871页

作者： Xun WEI yan zhang Xuefa SHI hui zhang Key Laboratory of Marine Geology and Metallogeny First Institute of OceanographyMinistry of Natural ResourcesQingdao 266061China Laboratory for Marine Geology Qingdao Marine Science and Technology CenterQingdao 266237China Shandong Key Laboratory of Deep Sea Mineral Resources Development(Preparatory) Qingdao 266061China

Oceanic intraplate volcanoes with linear age progressions are usually accepted to be derived from melting of an upwelling mantle *** seamount groups in NW Pacific,however,show complex age-distance relationships that are difficult to explain using the classic“mantle plume hypothesis”,and thus their origins are *** this study,we present ^(40)Ar-^(39)Ar age,geochemical,and Sr-Nd-Pb-Hf isotopic data of lavas from Hemler,Vlinder,and Il’ichev seamounts in NW Pacific,to elucidate their petrogenesis and geodynamic *** lavas from Hemler,Vlinder,and Il’ichev seamounts are classified as alkali basalt,basanite/nephelinite,and *** with Mg O>8 wt.%exhibit high contents of CaO,FeO^(T),and TiO_(2),similar to the composition of melts formed from reaction between carbonated eclogite-derived melts and fertile *** lavas have elevated Zr/Hf ratios(40.6-45.2)and negative Zr and Hf anomalies,indicating the presence of a carbonate component in the mantle *** are enriched in incompatible trace elements and have enriched mantle 1(EM1)-like SrNd-Pb-Hf isotopic *** isotopic compositions of Vlinder,Il’ichev basanite,and Hemler lavas in this study are similar to the Rarotonga *** occurring at the same seamount,the Il’ichev alkali basalts display more depleted SrNd-Hf isotopic compositions compared to Il’ichev *** to plate tectonic reconstruction results,the ages of Hemler(100.1 Ma),Vlinder pre-(100.2 Ma)and post-shield(87.5 Ma),and Il’ichev(56.4 Ma)lavas clearly deviate from the Macdonald,Arago,Rarotonga,and Samoa hotspot tracks,indicating that they cannot directly originate from mantle *** propose that in the mid-Cretaceous,when the Pacific plate passed over Rarotonga hotspot,melting of Rarotonga plume formed the Vlinder(main-shield stage),Pako,and Ioah *** Rarotonga(and possibly Samoa)plume materials would have been dispersed into the surrounding asthenosphere by mantle conve

关键词： Mantle plume Magellan seamount trail Carbonated mantle component Hotspot Lithosphere extension

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