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完善经济适用房政策的思考

西安航空技术高等专科学校学报 2007年第6期25卷 38-40页

作者：严碧峰西安航空技术高等专科学校招生就业指导中心陕西西安710077

经济适用房政策,是我国现阶段用来解决中低收入群体住房问题的有效措施。通过对经济适用房政策存在问题的分析,对如何完善经济适用房政策,解决中低收入群体的住房问题提出了界定购房对象、政策补贴、拓展二手房市场等建议。

关键词：经济适用房二手房中低收入群体住房政策个人信用制度

缺血性脑卒中患者血清胱抑素C与颈动脉粥样硬化间关系的研究进展

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中国动脉硬化杂志 2016年第9期24卷 969-972页

作者：刘琰凤吐尔逊.沙比尔努尔比亚.吾买尔新疆医科大学第一附属医院神经内科新疆乌鲁木齐市830054

胱抑素C作为一种半胱氨酸蛋白酶抑制剂,是反映肾功能受损的指标。目前,有研究认为胱抑素C可能是动脉粥样硬化形成的危险因素,在血管损害中发挥着重要作用,与缺血性脑卒中患者颈动脉粥样硬化的发生、发展以及疾病的预后具有一定的相关性... 详细信息

胱抑素C作为一种半胱氨酸蛋白酶抑制剂,是反映肾功能受损的指标。目前,有研究认为胱抑素C可能是动脉粥样硬化形成的危险因素,在血管损害中发挥着重要作用,与缺血性脑卒中患者颈动脉粥样硬化的发生、发展以及疾病的预后具有一定的相关性。本文就近年对缺血性脑卒中患者胱抑素C与颈动脉粥样硬化的相关性研究作一综述。

关键词：胱抑素C 颈动脉粥样硬化缺血性脑卒中

Hypoxia-preconditioned bone marrow-derived mesenchymal stem cells protect neurons from cardiac arrest-induced pyroptosis

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Neural Regeneration Research 2025年第4期20卷 1103-1123页

作者： Xiahong Tang Nan Zheng Qingming Lin yan You Zheng Gong yangping Zhuang Jiali Wu Yu Wang Hanlin Huang Jun Ke feng Chen Shengli Clinical Medical College of Fujian Medical University Fujian Medical UniversityFuzhouFujian ProvinceChina Department of Emergency Fujian Provincial HospitalFuzhouFujian ProvinceChina Fujian Provincial Key Laboratory of Emergency Medicine FuzhouFujian ProvinceChina The Second Department of Intensive Care Unit Fujian Provincial Hospital South BranchFuzhouFujian ProvinceChina

Cardiac arrest can lead to severe neurological impairment as a result of inflammation,mitochondrial dysfunction,and post-cardiopulmonary resuscitation neurological *** preconditioning has been shown to improve migration and survival of bone marrow–derived mesenchymal stem cells and reduce pyroptosis after cardiac arrest,but the specific mechanisms by which hypoxia-preconditioned bone marrow–derived mesenchymal stem cells protect against brain injury after cardiac arrest are *** this end,we established an in vitro co-culture model of bone marrow–derived mesenchymal stem cells and oxygen–glucose deprived primary neurons and found that hypoxic preconditioning enhanced the protective effect of bone marrow stromal stem cells against neuronal pyroptosis,possibly through inhibition of the MAPK and nuclear factor κB ***,we transplanted hypoxia-preconditioned bone marrow–derived mesenchymal stem cells into the lateral ventricle after the return of spontaneous circulation in an 8-minute cardiac arrest rat model induced by *** results showed that hypoxia-preconditioned bone marrow–derived mesenchymal stem cells significantly reduced cardiac arrest–induced neuronal pyroptosis,oxidative stress,and mitochondrial damage,whereas knockdown of the liver isoform of phosphofructokinase in bone marrow–derived mesenchymal stem cells inhibited these *** conclude,hypoxia-preconditioned bone marrow–derived mesenchymal stem cells offer a promising therapeutic approach for neuronal injury following cardiac arrest,and their beneficial effects are potentially associated with increased expression of the liver isoform of phosphofructokinase following hypoxic preconditioning.

关键词： bone marrow–derived mesenchymal stem cells cardiac arrest cardiac resuscitation hypoxic preconditioning liver isoform of phosphofructokinase mitochondria neuroinflammation oxidative stress pyroptosis reactive oxygen species

植入式导管药盒系统在肝癌介入治疗中的应用价值(附229例对比分析)

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实用放射学杂志 2001年第2期17卷 122-124页

作者：赵玉锋王瑞燕冯乃华毕宝林杨效经李云生淄博54862部队医院肿瘤科!山东淄博255020 解放军106医院内四科解放军89医院放射科淄博市第三人民医院外科

目的 :研究植入式导管药盒系统 (PCS)在肝癌介入治疗中的应用价值。方法 :2 2 9例介入治疗的原发性肝癌病例按不同介入治疗方法分为TACE组、PCS组和TAI组。对三组疗效和方法进行了对比分析。结果 :PCS组缓解率虽然与TAI组无显著差异 ,但... 详细信息

目的 :研究植入式导管药盒系统 (PCS)在肝癌介入治疗中的应用价值。方法 :2 2 9例介入治疗的原发性肝癌病例按不同介入治疗方法分为TACE组、PCS组和TAI组。对三组疗效和方法进行了对比分析。结果 :PCS组缓解率虽然与TAI组无显著差异 ,但 1,2年生存率却明显高于TAI组。但随着时间推移 ,生存率下降显著 ,与TAI的差异逐渐缩小 ,3年生存率两组已无明显差异 ,而TACE与上述两组的差异却越来越明显。结论 :PCS在不能栓塞的肝癌介入治疗中有较好的应用价值。髂外动脉穿刺植入药盒优于股动脉及锁骨下动脉法

关键词：肝肿瘤介入治疗植入药盒

Disinfection byproduct precursor removal by enhanced coagulation and their distribution in chemical fractions

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Journal of Environmental Sciences 2013年第11期25卷 2207-2213页

作者： yanmei Zhao feng Xiao Dongsheng Wang Mingquan yan Zhe bi Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Department of Environmental Engineering Peking University

Raw water from the Songhua River was treated by four types of coagulants, ferric chloride （FeC13）, aluminum sulfate （A12（504）3）, polyaluminum chloride （PACl） and composite polyaluminum （HPAC）, in order to remove dissolved organic matter （DOM）. Considering the disinfection byproduct （DBP） precursor treatability, DOM was divided into five chemical fractions based on resin adsorption. Trihalomethane formation potential （THMFP） and haloacetic acid formation potential （HAAFP） were measured for each fraction. The results showed that hydrophobic acids （HoA）, hydrophilic matter （HIM） and hydrophobic neutral （HoN） were the dominant fractions. Although both HoN and HoA were the main THM precursors, the contribution for THMFP changed after coagulation. Additionally, HoA and HiM were the main HAA precursors, while the contribution of HoN to HAAFP significantly increased after coagulation. HoM was more easily removed than HiM, no matter which coagulant was used, especially under enhanced coagulation conditions. DOC removal was highest for enhanced coagulation using FeCl3 while DBPFP was lowest using PAC1. This could indicate that not all DOC fractions contained the precursors of DBPs. Reduction of THMFP and HAAFP by PAC1 under enhanced coagulation could reach 51% and 59% respectively.

关键词： trihalomethanes haloacetic acids dissolved organic matter chemical fractionation enhanced coagulation

Modulation of tumor microenvironment by metal-organic-framework-derived nanoenzyme for enhancing nucleus-targeted photodynamic therapy

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Nano Research 2020年第6期13卷 1527-1535页

作者： Xuemei Zeng Shuangqian yan Peng Chen Wei Du bi-feng Liu The Key Laboratory for biomedical Photonics of MOE at Wuhan National Laboratory for Optoelectronics-Hubei bioinformatics&Molecular Imaging Key Laboratory Systems Biology ThemeDepartment of Biomedical EngineeringCollege of Life Science and TechnologyHuazhong University of Science and TechnologyWuhan430074China

Photodynamic therapy(PDT)is a promising strategy for tumor ***,its therapeutic efficacy is compromised by the unsatisfactory cytotoxicity to specific subcellular organelles and insidious tumor microenvironment properties like hypoxia and high glutathione ***,we fabricated a novel nanoenzyme that derived from metal-organic framework(MOF)with intrinsic catalase-like activities to decompose H2O2 to O2 and simultaneous glutathione consumption for enhancing PDT *** obtained Mn3O4 nanoparticle shows a larger pore size and surface area compared to native MOF particles,which can be used to load high dose *** decorated with AS1411 aptamer and polyethylene glycol(PEG),the obtained Mn3O4-PEG@C&A particle exhibits excellent stability and cell nucleus targeting ***,Mn3O4-PEG@C&A particle inhibited the tumor growth in the mouse model with high efficacy without any *** is the first report that applied MOF-derived nanoparticle to nucleus-targeted *** may provide a new approach for designing functional nanoenzyme to subcellular organelles-targeted tumor modulation.

关键词： nanoenzyme metal-organic framework catalase-like activity GSH consumption photodynamic therapy

Spatiotemporal characteristics and influencing factors of vegetation water use efficiency on the Tibetan Plateau in 2001–2020

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Journal of Geographical Sciences 2025年第1期 39-64页

作者： HE Chenyang WANG yanjiao yan feng LU Qi School of Ecological and Environmental Science East China Normal University Institute of Ecological Conservation and Restoration Chinese Academy of Forestry National Climate Center China Meteorological Administration

Water use efficiency （WUE）,as a pivotal indicator of the coupling degree within the carbon–water cycle of ecosystems,holds considerable importance in assessment of the carbon–water balance within terrestrial ***,in the context of global warming,WUE evolution and its primary drivers on the Tibetan Plateau remain *** study employed the ensemble empirical mode decomposition method and the random forest algorithm to decipher the nonlinear trends and drivers of WUE on the Tibetan Plateau in 2001–*** indicated an annual mean WUE of 0.8088 gC/mm·m2across the plateau,with a spatial gradient reflecting decrease from the southeast toward the *** manifesting monotonous trends of increase or decrease in WUE accounted for 23.64%and 9.69%of the total,***,66.67%of the region exhibited trend reversals,i.e.,39.94%of the area of the Tibetan Plateau showed transition from a trend of increase to a trend of decrease,and 26.73%of the area demonstrated a shift from a trend of decrease to a trend of *** factors accounted for 70.79%of the variability in *** leaf area index and temperature served as the major driving forces of WUE variation.

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A Spatiotemporal Causality Based Governance Framework for Noisy Urban Sensory Data

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Journal of Computer Science & Technology 2020年第5期35卷 1084-1098页

作者： bi-Ying yan Chao yang Pan Deng Qiao Sun feng Chen yang Yu Institute of Software Chinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China School of Mathematical Sciences.Peking University Beijing 100871China Peng Cheng Laboratory Shenzhen 518052China Research Institute for Frontier Science Beihang UniversityBeijing 100191China Guiyang Academy of Information Technology Guiyang 550081China Guiyang Municipal Commission of Transport Guiyang 550003China

Urban sensing is one of the fundamental building blocks of urban *** uses various types of sensors deployed in different geospatial locations to continuously and cooperatively monitor the natural and cultural environment in urban ***,issues such as uneven distribution,low sampling rate and high failure ratio of sensors often make their readings less *** paper provides an innovative framework to detect the noise data as well as to repair them from a spatial-temporal causality perspective rather than to deal with them *** can be achieved by connecting data through monitored objects,using the Skip-gram model to estimate spatial correlation and long shortterm memory to estimate temporal *** framework consists of three major modules:1)a space embedded bidirectional Long Short-Term Memory(biLSTM)-based sequence labeling module to detect the noise data and the latent missing data;2)a space embedded biLSTM-based sequence predicting module calculating the value of the missing data;3)an object characteristics fusion repairing module to correct the spatial and temporal dislocation sensory *** approach is evaluated with real-world data collected by over 3000 electronic traffic bayonet devices in a citywide scale of a medium-sized city in China,and the result is superior to those of several referenced *** a 12.9%improvement,in data accuracy over the raw data,the proposed framework plays a significant,role in various real-world use cases in urban governance,such as criminal investigation,traffic violation monitoring,and equipment maintenance.

关键词： trajectory data recurrent neural network spatiotemporal(ST)big data urban computing

Hydrothermal in situ Ligand Synthesis from 1,10-Phenanthroline-5,6-dione and Characterization of 1D Coordination Polymers [Co(bpdc)(H_2O)_3]·H_2O and [Cu(bpy)V_2O_6]

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Chemical Research in Chinese Universities 2007年第3期23卷 250-253页

作者： WANG Xiu-li bi yan-feng LIN Hong-yan LIU Guo-cheng Faculty of Chemistry and Chemical Engineering Bohai University Jinzhou 121000 P. R. China

Hydrothermal treatment of MCl2 （ M = Co or Cu ） , NH4 VO3, and 1,10-phenanthroline-5,6-dione （pdon） resulted in the formation of a duplex coordination polymer [ Co （ bpdc ）（ H2O ） 3 ] · H2O （ bpdc = 2,2＇-bipyridine-3,3＇-dicarboxylate） and a chain-like coordination polymer [ Cu （bpy） V2O6 ] （ bpy = 2,2＇-bipyridine ）. X-ray single-crystal structural analysis shows that under hydrothermal conditions and in the presence of different transition metals, the organic reagent pdon was transformed in situ into bpdc and bpy, respectively. Mechanism of the in situ ligand synthesis reaction has been discussed.

关键词： Hydrothermal synthesis In situ Ligand synthesis Coordination polymer Mechanism