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The development of graphene-based devices for cell biology research

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Frontiers of Materials Science 2014年第2期8卷 107-122页

作者： Zhi-qin yan Wei ZHANG School of Mechanical Jinzhong University Yuci Jinzhong 030600 China CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety National Center for Nanoscience and Technology 11 Beiyitiao 7hongguancun Beijing 100190 China

Graphene has emerged as a new carbon nanoform with great potential in many applications due to its exceptional physical and chemical properties. Especially, graphene and its derivatives are also gaining a lot of interest in the biomedical field as new components for biosensors, tissue engineering, and drug delivery. This review presents unique properties of graphene, the bio-effects of graphene and its derivatives, especially their interactions with cells and the development of graphene-based biosensors and nanomedicines for cancer diagnosis and treatment.

关键词： graphene graphene oxide (GO) cell sensor cancer

单片机的16×16动态扫描LED点阵模块设计

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福建电脑 2025年第1期41卷 37-40页

作者：张海勇秦艳武汉东湖学院电子信息工程学院武汉430212 武汉光迅科技股份有限公司模块开发部武汉430205

为实现静态字符和滚动字符的显示,本文设计了一个16×16单色点阵显示模块。采用4片8×8单色点阵模块构成16×16点阵模块,并使用Altium Designer进行电路原理图和印刷电路板的整体设计。控制系统基于51单片机最小系统,显示程序在Keil C5... 详细信息

为实现静态字符和滚动字符的显示,本文设计了一个16×16单色点阵显示模块。采用4片8×8单色点阵模块构成16×16点阵模块,并使用Altium Designer进行电路原理图和印刷电路板的整体设计。控制系统基于51单片机最小系统,显示程序在Keil C51环境中编写,芯片选用74HC595和74HC138。该模块设计整体工作量较小,设计过程有益于锻炼实际动手能力以及提高分析问题和解决问题的能力。

关键词：点阵模块电路设计显示程序硬件驱动

Effect of small peptide(P-15) on HJMSCs adhesion to hydroxyap-atite

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Science China(Physics,Mechanics & Astronomy) 2016年第2期59卷 102-107,109-112页

作者： Wei Cheng Xin Tong qin Gang Hu Yong Bin Mou Hai yan qin Nanjing Stomatological Hospital Medical School of Nanjing University Central Laboratory of Stomatology Nanjing Stomatological Hospital

P-15, a synthetic peptide of 15-amino acids, has been tested in clinical trials to enhance cell adhesion and promote osseointe-gration. This feature of P-15 has also inspired the development of designing new bone substitute materials. Despite the increasing applications of P-15 in bone graft alternatives, few studies focus on the mechanism of cell adhesion promoted by P-15 and the mechanical property changes of the cells interacting with P-15. In this article, we used atomic force microscope(AFM) based single cell indentation force spectroscopy to study the impact of P-15 on the stiffness and the adhesion ability of human jaw bone mesenchymal stem cells(HJMSCs) to hydroxyapatite(HA). We found that the stiffness of HJMSCs increases as the concentration of P-15 grows in short culture intervals and that the adhesion forces between HJMSCs and HA particles in both the presence and absence of P-15 are all around 30 p N. Moreover, by calculating the binding energy of HJMSCs to HA particles mixed with and without P-15, we proved that P-15 could increase the adhesion energy by nearly four times. Scanning electron microscope(SEM) was also exploited to study the morphology of HJMSCs cultured in the presence and absence of P-15 on HA disc surface for a short term. Apparent morphological differences were observed between the cells cultured with and without P-15. These results explain the probable underlying adhesion mechanism of HJMSC promoted by P-15 and can serve as the bases for the design of bone graft substitute materials.

关键词： atomic force microscopy (AFM) cell stiffness force spectroscopy

Exact Solutions of a Generalized Multi-Fractional Nonlinear Diffusion Equation in Radical Symmetry

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Communications in Theoretical Physics 2009年第11期52卷 857-861页

作者： LIU yan-qin MA Jun-Hai School of Management Tianjin University Tianjin 300072 China Department of Mathematics Dezhou University Dezhou 253023 China

This paper is devoted to investigating exact solutions of a generalized fractional nonlinear anomalousdiffusion equation in radical *** presence of external force and absorption is also *** firstinvestigate the nonlinear anomalous diffusion equations with one-fractional derivative and then multi-fractional *** situations,we obtain the corresponding exact solutions,and the solutions found here can have a compact behavioror a long tailed behavior.

关键词： fractional derivative multi-fractional diffusion equation anomalous diffusion equation

Primal-dual Interior-point Algorithms for Second-order Cone Optimization Based on a New Parametric Kernel Function

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Acta Mathematica Sinica,English Series 2007年第11期23卷 2027-2042页

作者： yan qin BAI Guo Qiang WANG Department of Mathematics College of Sciences Shanghai University Shanghai 200444 P. R. China College of Vocational Technology Shanghai University of Engineering Science Shanghai 200437 P. R. China

A class of polynomial primal-dual interior-point algorithms for second-order cone optimization based on a new parametric kernel function, with parameters p and q, is presented. Its growth term is between linear and quadratic. Some new tools for the analysis of the algorithms are proposed. The complexity bounds of O（√Nlog N log N/ε） for large-update methods and O（√Nlog N/ε） for smallupdate methods match the best known complexity bounds obtained for these methods. Numerical tests demonstrate the behavior of the algorithms for different results of the parameters p and q.

关键词： second-order cone optimization linear optimization interior-point methods large- and small-update methods polynomial-time complexity

Ionic Liquids-Assisted Highly Luminescent Copper Nanoclusters with Triangle Supramolecular Nanostructures

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Chinese Journal of Chemistry 2021年第7期39卷 1867-1870页

作者： Bingyan Han qin yan Ze Xin Qifang yan Jingmei Jiang State Key Laboratory of Fine Chemicals Dalian University of TechnologyDalianLiaoning116023 China School of Chemical Engineering Dalian University of TechnologyPanjinLiaoning124221 China

Main observation and conclusion A novel and facile approach towards highly luminescent CuNCs@MMI(2-mercapto-1-methylimidazole)has been developed within 30 s with the assistance of ionic liquids(ILs)-[Bmim]BF_(4).FT-IR... 详细信息

关键词： Nanostructures Ionic liquids Aggregation Surface analysis [Bmim]BF_(4)

Spatiotemporal variation of surface albedo and its influencing factors in northern Xinjiang, China

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Journal of Arid Land 2023年第11期15卷 1315-1339页

作者： YUAN Shuai LIU Yongqiang qin yan ZHANG Kun College of Geography and Remote Sensing Sciences Xinjiang UniversityUrumqi 830046China Xinjiang Key Laboratory of Oasis Ecology Xinjiang UniversityUrumqi 830046China

Surface albedo is a quantitative indicator for land surface processes and climate modeling,and plays an important role in surface radiation balance and climate *** this study,by means of the MCD43A3 surface albedo product developed on the basis of Moderate Resolution Imaging Spectroradiometer(MODIS),we analyzed the spatiotemporal variation,persistence status,land cover type differences,and annual and seasonal differences of surface albedo,as well as the relationship between surface albedo and various influencing factors(including Normalized Difference Snow Index(NDSI),precipitation,Normalized Difference Vegetation Index(NDVI),land surface temperature,soil moisture,air temperature,and digital elevation model(DEM))in the north of Xinjiang Uygur Autonomous Region(northern Xinjiang)of Northwest China from 2010 to 2020 based on the unary linear regression,Hurst index,and Pearson's correlation coefficient *** with the random forest(RF)model and geographical detector(Geodetector),the importance of the above-mentioned influencing factors as well as their interactions on surface albedo were quantitatively *** results showed that the seasonal average surface albedo in northern Xinjiang was the highest in winter and the lowest in *** annual average surface albedo from 2010 to 2020 was high in the west and north and low in the east and south,showing a weak decreasing trend and a small and stable overall *** cover types had a significant impact on the variation of surface *** annual average surface albedo in most regions of northern Xinjiang was positively correlated with NDSI and precipitation,and negatively correlated with NDVI,land surface temperature,soil moisture,and air *** addition,the correlations between surface albedo and various influencing factors showed significant differences for different land cover types and in different *** be specific,NDSI had the largest influence on surface albedo,follow

关键词： surface albedo MCD43A3 Hurst index random forest(RF)model geographical detector(Geodetector) Normalized Difference Snow Index(NDSI) northern Xinjiang

Family-Society: The Dual Identity of Chinese Women

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学术界 2020年第5期 210-217页

作者： Liu Ning qin yan School of Marxism Northwestern Polytechnical University Xi’an Shaanxi 710129

The analysis of the historical and theoretical origins of the dual identity of Chinese women based on the Marxist view of family-society enables a more scientific and reasonable explanation to the unity of history and logic of Chinese women’s dual *** the guidance of the Marxist concept of family-society,Chinese women will achieve development in both family space and social space;meanwhile,Chinese women in the dual identity development carry the home-state emotion different from that of western women’s;cultivating women’s awareness of family identity is of great significance to the construction of family style or national style in the new era of socialism with Chinese characteristics.

关键词： Chinese women Marxist view of family-society dual identity of family-society family space social space Interpretation of Marxist view of family-society

Parametric Research of Experiments on a Carangiform Robotic Fish

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Journal of Bionic Engineering 2008年第2期5卷 95-101页

作者： qin yan Zhen Han Shi-wu Zhang Jie yang Department of Precision Machinery and Precision Instrumentation University of Science and Technology of China Hefei 230026 P R. China

In this paper, a carangiform robotic fish with 4-DoF （degree of freedom） tail has been developed. The robotic fish has capability of swimming under two modes that are radio control and autonomous swimming. Experiments were conducted to investigate the influences of characteristic parameters including the frequency, the amplitude, the wave length, the phase difference and the coefficient on forward velocity. The experimental results shown that the swimming performance of the robotic fish is affected mostly by the characteristic parameters observed.

关键词： biomimetic robotic fish experimental parameter matrix undulation equation body length velocity