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Journal of Traditional Chinese Medicine 2024年第1期44卷 222-223页

作者： XING Yunqi LI Junxiang yuan yali MAO Tangyou Gastroenterology Department Dongfang HospitalBeijing University of Chinese MedicineBeijing 100078China Department of Hepatology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 201203China

To the Editors:We read with great interest the study recently published by Sun et al 1 entitled“Electroacupuncture at Tianshu(ST25)and Zusanli(ST36)alleviates stress-induced irritable bowel syndrome in mice by modulating gut microbiota and corticotropin-releasing factor”in which the microbial details of electroacupuncture(EA)-induced protection in irritable bowel syndrome(IBS)were investigated.

关键词： releasing treatment details

Cetus: an efficient symmetric searchable encryption against file-injection attack with SGX

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Science China(Information Sciences) 2021年第8期64卷 195-212页

作者： Yanyu HUANG Siyi LV Zheli LIU Xiangfu SONG Jin LI yali yuan Changyu Dong College of Cyber Science and the College of Computer Science Tianjin Key Laboratory of Network and Data Security TechnologyNankai University School of Computer Science and Technology Shandong University School of Computer Science Guangzhou University Department of Computer Science University of G?ttingen School of Computing Newcastle University

Symmetric searchable encryption(SSE) allows the users to store and query their private data in the encrypted database. Many SSE schemes for different scenarios have been proposed in the past few years, however, most of these schemes still face more or fewer security issues. Using these security leakages,many attacks against the SSE scheme have been proposed, and especially the non-adaptive file injection attack is the most serious. Non-adaptive file injection attack(NAFA) can effectively recover some extremely important private information such as keyword plaintext. As of now, there is no scheme that can effectively defend against such attacks. We first propose the new security attribute called toward privacy to resist nonadaptive file injection attacks. We then present an efficient SSE construction called Cetus to achieve toward privacy. By setting up a buffer and designing the efficient oblivious reading algorithm based on software guard extensions(SGX), we propose the efficient one-time oblivious writing mechanism. Oblivious writing protects the update pattern and allows search operations to be performed directly on the data. The experiment results show that Cetus achieves O(aw) search time and O(1) update communication. The practical search time, communication, and computation overheads incurred by Cetus are lower than those of state-of-the-art.

关键词： searchable encryption SGX technique file injection attack forward/toward privacy cloud databases

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A Function-Aware Mimic Defense Theory and Its Practice

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China Communications 2024年第8期21卷 192-210页

作者： He Jiajun yuan yali Liang Sichu Fu Jiale Zhu Hongyu Cheng Guang School of Mathematics Southeast UniversityNanjing 211189China School of Cyber Science and Engineering Southeast UniversityNanjing 211189China School of Artificial Intelligence Southeast UniversityNanjing 211189China State Key Laboratory for Novel Software Technology Nanjing UniversityNanjing 210093China

In recent years,network attacks have been characterized by diversification and scale,which indicates a requirement for defense strategies to sacrifice generalizability for higher *** the latest theoretical achievement in active defense,mimic defense demonstrates high robustness against complex *** study proposes a Function-aware,Bayesian adjudication,and Adaptive updating Mimic Defense(FBAMD)theory for addressing the current problems of existing work including limited ability to resist unknown threats,imprecise heterogeneous metrics,and over-reliance on relatively-correct *** incorporates three critical ***,the common features of executors’vulnerabilities are obtained from the perspective of the functional implementation(i.e,input-output relationships extraction).Secondly,a new adjudication mechanism considering Bayes’theory is proposed by leveraging the advantages of both current results and historical ***,posterior confidence can be updated regularly with prior adjudication information,which provides mimic system *** experimental analysis shows that FBAMD exhibits the best performance in the face of different types of attacks compared to the state-of-the-art over real-world *** study presents a promising step toward the theo-retical innovation of mimic defense.

关键词： Bayesian theory confidence functional implementation mimic defense

Implementation of a Comprehensive Information Management Platform for Public Security Based on Java Technology

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计算机科学与技术汇刊（中英文版） 2023年第1期10卷 11-16页

作者： Jin Xue yali yuan Hebei North University ZhangjiakouHebei075000China

Due to the rapid development of electronic information technology,the development of Internet technology and system software development technology has become more and more ***,along with the development of public security,there are more and more provisions for standard administrative department management system,improving office efficiency and enhancing decision ***,it is of great practical value to design and complete a comprehensive public security business information *** on java technology,this paper designs and builds a comprehensive information management platform for public security through the analysis of comprehensive public security business,and also gets good feedback during the actual test,which confirms the feasibility of the system.

关键词： Public Security Comprehensive Business Information System Java Workflow Web Information Security

Electrochemical immunosensor for detecting the spore wall protein of Nosema bombycis based on the amplification of hemin/G-quadruplex DNAzyme concatamers functionalized Pt@Pd nanowires

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Electrochemical immunosensor for detecting the spore wall pr...

第十二届家（柞）蚕遗传育种暨良种繁育学术研讨会

作者：王琴 Yue Song Yaqin Chai Guoqing Pan Tian Li yali yuan 袁若 State Key Laboratory of Silkworm Genome Biology Key Laboratory of Luminescent and Real-Time Analytical Chemistry Ministry of Education College of Chemistry and Chemical Engineering Southwest University

In this work, an ultrasensitive electrochemical immunosensor for detecting the Pebrine disease related spore wall protein of Nosema bombycis(SWP N.b) was fabricated based on the amplification of hemin/G-quadruplex functionalized Pt@Pd nanowires(Pt@PdNWs). The synthesized Pt@Pd NWs possessed large surface area, which could effectively improve the immobilization amount of hemin/G-quadruplex DNAzyme concatamers produced via hybridization chain reaction(HCR). In the presence of SWP N.b, the hemin/G-quadruplex labeled Pt@PdNWs bioconjugations was captured on electrode surface and thus obtained electrochemical signal. After the addition of NADH into the electrolytic cell, hemin/G-quadruplex firstly acted as an NADH oxidase to locally produce HO in the presence of dissolved O. Then, the generated HO would be quickly reduced via hemin/G-quadruplex as a horseradish peroxidase mimicking(HRP-mimicking) DNAzyme, which finally promoted the self-redox reaction of hemin/G-quadruplex and a greatly enhanced electrochemical signal was obtained. Furthermore, Pt@Pd NWs with excellent electrocatalytic performance could also amplify electrochemical signal. With these amplification factors, the electrochemical immunosensor exhibited a wide linear range from 0.001 ng m L-1 to 100 ng m L-1 with a detection limit(LOD) of 0.24 pg m L-1, providing a new promise for the diagnosis of Pebrine disease.

关键词： Pebrine disease Electrochemical immunosensor Electrocatalytic Hemin/G-quadruplex Pt@Pb nanowires Nosema bombycis

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关于完善我国财政转移支付的探讨

特区经济 2008年第5期 78-80页

作者：袁亚丽上海海事大学经济管理学院上海200135

有关实证研究表明,我国财政转移支付可以通过均衡地方政府财力缩小地区差距。然而,不断加大力度的财政转移支付功效尚嫌不足,还存在一些亟待解决的问题。完善我国财政转移支付可采取的措施包括:明确各级政府的事权与财权;健全有关法律... 详细信息

有关实证研究表明,我国财政转移支付可以通过均衡地方政府财力缩小地区差距。然而,不断加大力度的财政转移支付功效尚嫌不足,还存在一些亟待解决的问题。完善我国财政转移支付可采取的措施包括:明确各级政府的事权与财权;健全有关法律法规体系和监督机制;进一步扩大转移支付规模,优化转移支付结构;统一转移支付分配标准,推广因素法;规范专项转移支付管理方式;切实推进省对下转移支付改革。

关键词：地区差距转移支付财力性转移支付专项转移支付因素法

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生物活性小分子过亚硝酸根

化学通报 1999年第2期 37-40页

作者：廖力夫袁亚莉邓健衡阳医学院化学教研室

过亚硝酸根可产生于生物系统，是一种强氧化剂、过氧化引发剂和硝化剂，可与多种生物物质反应，在许多生物过程中都起着重要作用。

关键词：过亚硝酸根生物活性生命科学

突发事件下城市群内旅客城际出行方式选择行为

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清华大学学报（自然科学版） 2022年第7期62卷 1142-1150页

作者：原雅丽杨小宝李虹慧四兵锋北京交通大学综合交通运输大数据应用技术交通运输行业重点实验室北京100044 交通运输部路网监测与应急处置中心北京100029

以城市群内旅客城际出行为研究对象,分析心理潜变量、城市群属性和突发事件等因素对城际出行方式选择行为的影响。基于京津冀旅客城市群内部城际出行问卷调查数据,构建突发事件下考虑心理潜变量的综合选择(integrated choice and latent... 详细信息

以城市群内旅客城际出行为研究对象,分析心理潜变量、城市群属性和突发事件等因素对城际出行方式选择行为的影响。基于京津冀旅客城市群内部城际出行问卷调查数据,构建突发事件下考虑心理潜变量的综合选择(integrated choice and latent variable,ICLV)模型进行实证分析。结果表明:考虑便捷性和乘车体验潜变量的混合选择模型对居民城际出行行为的拟合优度更高;城市群属性方面,起讫点城市类型、出行距离和起讫点间铁路车次数量对出行方式选择有显著影响;突发事件方面,雾霾天气下选择铁路出行的概率提高25.69%,雨天选择小汽车出行的概率提高31.63%,雪天选择小汽车出行的概率相对降低,发生阻断事件时选择小汽车出行的概率升高。研究结果有助于深入理解城市群内城际出行方式选择行为,为突发事件下城际出行需求的差异化出行诱导和需求管控提供科学依据。

关键词：城市群出行方式选择综合选择模型城际出行潜变量突发事件

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感染性疾病mNGS检测结果解读的应用

中华预防医学杂志 2023年第7期57卷 1124-1130页

作者：蒋析文梁志坤曾莉袁亚丽卫生部医药生物工程技术研究中心、临床医学分子诊断国家地方联合工程实验室广州510665

由于技术的快速发展和成本的大幅降低,宏基因组下一代测序(metagenomic next-generation sequencing,mNGS)的应用正在从研究转向临床实验室。尽管许多研究和病例报告已经证实mNGS在改进传染病的预防、诊断、治疗和追踪方面取得了成功,... 详细信息

由于技术的快速发展和成本的大幅降低,宏基因组下一代测序(metagenomic next-generation sequencing,mNGS)的应用正在从研究转向临床实验室。尽管许多研究和病例报告已经证实mNGS在改进传染病的预防、诊断、治疗和追踪方面取得了成功,但仍有一些障碍必须克服。mNGS的结果会展示样本中的全部可能病原体,然而面对着数千种会感染人类的微生物,如何准确判读其中关键致病病原体是具有挑战性的。迄今为止,在临床实践中,mNGS的解读标准也尚未统一。本文就mNGS在不同系统中病原体感染的结果解读,mNGS结果的临床解读和应用规则,以及mNGS解读在病原体诊断中面临的挑战进行阐述。

关键词：宏基因组感染性疾病结果解读

碳点荧光传感器:碳点合成、发光调控及信号构建

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分析试验室 2022年第12期41卷 1473-1484页

作者：秦雪非颜文菊周雪英袁亚利桂林理工大学化学与生物工程学院桂林541004

碳点作为一种新型的荧光纳米材料,有突出的低毒性和生物相容性,在环境及生命分析领域有巨大的应用前景。与传统的有机荧光分子相比,碳点具有良好的抗光漂白能力,其较大的斯托克斯位移可以减少背景干扰,是构建荧光传感器的首选材料之一... 详细信息

碳点作为一种新型的荧光纳米材料,有突出的低毒性和生物相容性,在环境及生命分析领域有巨大的应用前景。与传统的有机荧光分子相比,碳点具有良好的抗光漂白能力,其较大的斯托克斯位移可以减少背景干扰,是构建荧光传感器的首选材料之一。本文对荧光碳点的合成进行了概述,从合成的角度探讨了碳点的发光调控机制,将影响碳点发光的因素归纳为温度、溶剂、碳前体和掺杂原子4个方面。结合碳点荧光发生变化的机理,对现有的碳点荧光传感信号构建方法进行了总结,并对碳点的进一步应用和研究提出了展望。

关键词：碳点荧光分析传感信号