检索结果-南通市图书馆

Chinese Chemical Letters 2024年第2期35卷 455-459页

作者： linlin Zhang Jianjun liao yakun li Wei Sun Chengjun Ge Key Laboratory of Agro-Forestry Environmental Processes and Ecological Regulation of Hainan Province School of Ecology and EnvironmentHainan UniversityHaikou 570228China Shandong Ocean Chemical Industry Scientific Research Institute Weifang 262737China

Establishing an effective charge transfer mechanism in carbon nitride(g-C_(3)N_(4))to enhance its photocatalytic activity remains a limiting ***,the combination design of a single Cu atom with hollow g-C_(3)N_(4)nanospheres(Cu-N_(3)structure)has been proven to offer significant opportunities for this crucial ***,this structure endows two pathways for charge transfer in the reaction,namely,the N atoms in the three-dimensional planar structure are only bonded with a single Cu atom,and charge transfer occurs between the plane and the layered structure due to the bending of the interlayered g-C_(3)N_(4)hollow ***,Cu-N_(3)and hollow nanosphere structures have been certified to greatly enhance the efficiency of photogenerated carrier separation and transfer between the layers and planes by ultrafast spectral *** a result,this catalyst possesses unparalleled photocatalytic ***,the hydrogen production rate up to 2040μmol h^(−1) g^(−1),which is 51 times that of pure C_(3)N_(4)under visible light *** photocatalytic degradation performance of tetracycline and oxidation performance of benzene is also expressed,with a degradation rate of 100%,a conversion of 97.3%and a selectivity of 99.9%.This work focuses on the structure-activity relationship to provide the possibilities for the development of potential photocatalytic materials.

关键词： g-C_(3)N_(4) Cu single atom Hollow nanospheres Charge transfer pathways Photocatalytic hydrogen production

Constructing built-in electric field in graphitic carbon nitride hollow nanospheres by co-doping and modified in-situ Ni_(2)P for broad spectrum photocatalytic activity

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2021年第31期90卷 143-149页

作者： linlin Zhang Wenxing Peng yakun li Rui Qin Dong Yue Chengjun Ge Jianjun liao ey Laboratory of Agro-Forestry Environmental Processes and Ecological Regulation of Hainan Province School of Ecological and Environmental SciencesHainan UniversityHaikou 570228China Shandong Ocean Chemical Industry Scientiﬁc Research Institute Weifang 262737China School of Materials Science and Engineering Hainan UniversityHaikou 570228China

The construction of built-in electric field is generally considered as an effective strategy to enhance photocatalytic performance due to its significant role in charge ***,a built-in electric field within g-C_(3)N_4 hollow nanospheres co-doped with sulfur and oxygen and modified in-situ Ni_(2)P is ***_(2)P/SO-HC_(3)N_4 exhibits significantly enhanced board spectrum photocatalytic properties for hydrogen precipitation(5.21 mmol h^(-1)g^(-1))and photocatalytic Cr(VI)reduction without the use of noble *** also achieves high photocatalytic sterilization activity and remarkable stability when used to completely inactivate ***(10~7)in 60 min under Vis-NIR light *** enhanced performance is attributed to the formation of a curved hollow sphere structure,which promotes the electron transfer between the inner and outer *** addition,co-doping inhibits the recombination of photogenerated carriers,and the built-in electric field recombined with Ni_(2)facilitates the electron transfer between the composite *** design strategy demonstrates an original method of devising multifunctional photocatalysts with enhanced activity and stability.

关键词： Photocatalysis Ni_(2)P g-C_(3)N_4 Hollow nanospheres Pt-free cocatalysts

Long-range Pt-Ni dual sites boost hydrogen evolution through optimizing the adsorption configuration

在线全文

学校读者我要写书评

暂无评论

Nano Research 2024年第5期17卷 3700-3706页

作者： Cong liu Pengfang Zhang Bing liu Qian Meng Xuzhao Yang yakun li Jingli Han Yao Wang Henan Province Engineering Research Center of Catalysis and Separation of Cyclohexanol College of Materials and Chemical EngineeringZhengzhou University of Light IndustryZhengzhou 450001China Shandong Provincial Key Laboratory of Chemical Energy Storage and Novel Cell Technology Liaocheng UniversityLiaocheng 252000China Key Laboratory of Synthetic and Biological Colloids Ministry of EducationSchool of Chemical and Material EngineeringInternational Joint Research Center for Photoresponsive Molecules and MaterialsJiangnan UniversityWuxi 214122China

Elaborated design of catalytic systems with a specifically tailored site distance to match the intermediates could substantially improve reaction kinetics and boost catalytic activity under unfavorable reaction *** the lower energy barriers of water splitting upon the synergy of dual sites,constructing synergistic Pt-M(M:transition metal)dual sites is an effective way to boost Pt with highly catalytic hydrogen evolution reaction(HER)*** unconventional“Ni(OH)_(2)-coated high-index Pt facets”was constructed to obtain long-range Pt-Ni dual sites,in which Ni composition as a water dissociation synergistic site can protect Pt from electrolyte corrosion and ensure efficient proton donation to Pt *** obtained long-range Pt-Ni dual sites present 3.84 mA·cm^(-1) of current density,which is 7.5 times specific activity higher than that of commercial Pt/C towards alkaline *** enhanced HER performance is attributed to synergistic catalysis on Pt-Ni dual sites accompanied by unconventional electron *** work illustrates a new strategy to construct the long-range dual sites by unconventional strategy for fundamental electrocatalytic study of alkaline HER.

关键词： long-range Pt-Ni dual sites electron transfer hydrogen evolution reaction sites synergy

An Integrated Research Framework for Effect of EWOM

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Systems Science and Information 2017年第4期8卷 343-355页

作者： Jie li Wenyi XUE Fang YANG yakun li School of Economics and Management Hebei University of TechnologyTianjin 300400China

With the development of the electronic commerce, the electronic word-of-mouth(e WOM)has become important reference information for consumer shopping. EWOM has attracted considerable interest from researchers in the past decade. In this paper, a research review is conducted and an integrated framework is proposed on the effect of e WOM. The effect of e WOM are influenced by its characteristics, communicators, and other factors. The characteristics of e WOM include the source,the volume and the valence. The communicators of e WOM refer to the sender, the receiver and the relationship between them. In addition, dispersion and consistency, persistence and observability,anonymity and deception, and community engagement are related factors for the effect of e WOM.

关键词： e-commerce word-of-mouth eWOM literature review research framework

Insertion sequence transposition activates antimycobacteriophage immunity through an Isr2-silenced lipid metabolism gene island

在线全文

学校读者我要写书评

暂无评论

mlife 2024年第1期3卷 87-100页

作者： yakun li Yuyun Wei Xiao Guo Xiaohui li lining Lu lihua Hu Zheng-Guo He State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources Guangxi Research Center for Microbial and Enzyme Engineering TechnologyCollege of Life Scienceand TechnologyGuangxi UniversityNanningChina

Insertion sequences(ISs)exist widely in bacterial genomes,but their roles in the evolution of bacterial antiphage defense remain to be ***,we report that,under the pressure of phage infection,the IS1o96 transposition of Mycobacterium smegmatis into the Isr2 gene can occur at high frequencies,which endows the mutant mycobacterium with a broad-spectrum antiphage ***2 functions as a negative regulator and directly silences expression of a gene island composed of 11 lipid metabolism-related *** complete or partial loss of the gene island leads to a significant decrease of bacteriophage adsorption to the mycobacterium,thus defending against phage ***,a phage that has evolved mutations in two tail-filament genes can re-escape from the Isr2 inactivation-triggered host *** study uncovered a new signaling pathway for activating antimycobacteriophage immunity by Is transposition and provided insight into the natural evolution of bacterial antiphage defense.

关键词： antiphage defense bacteriophage gene island insertion sequence mycobacteria

Decreased levels of phosphorylated synuclein in plasma are correlated with poststroke cognitive impairment

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2598-2610页

作者： Yi Wang Yuning li yakun Gu Wei Ma Yuying Guan Mengyuan Guo Qianqian Shao Xunming Ji Jia liu Department of Clinical Laboratory Beijing Bo’ai HospitalChina Rehabilitation Research CenterCapital Medical UniversityBeijingChina Beijing Institute of Brain Disorders Laboratory of Brain DisordersMinistry of Science and TechnologyCollaborative Innovation Center for Brain DisordersBeijing Advanced Innovation Center for Big Data-based Precision MedicineCapital Medical UniversityBeijingChina Department of Neurosurgery Xuanwu HospitalCapital Medical UniversityBeijingChina

Poststro ke cognitive impairment is a major secondary effect of ischemic stroke in many patients;however,few options are available for the early diagnosis and treatment of this *** aims of this study were to(1)determine the specific relationship between hypoxic andα-synuclein during the occur of poststroke cognitive impairment and(2)assess whether the serum phosphorylatedα-synuclein level can be used as a biomarker for poststro ke cognitive *** found that the phosphorylatedα-synuclein level was significantly increased and showed pathological aggregation around the cerebral infa rct area in a mouse model of ischemic *** addition,neuronalα-synuclein phosphorylation and aggregation were observed in the brain tissue of mice subjected to chronic hypoxia,suggesting that hypoxia is the underlying cause ofα-synuclein-mediated pathology in the brains of mice with ischemic *** phosphorylatedα-synuclein levels in patients with ischemic stroke were significantly lower than those in healt hy subjects,and were positively correlated with cognition levels in patients with ischemic ***,a decrease in serum high-density lipoprotein levels in stroke patie nts was significantly correlated with a decrease in phosphorylatedα-synuclein *** ischemic stroke mice did not show significant cognitive impairment or disrupted lipid metabolism 14 days after injury,some of them exhibited decreased cognitive function and reduced phosphorylatedα-synuclein *** together,our results suggest that serum phosphorylatedα-synuclein is a potential biomarker for poststroke cognitive impairment.

关键词： biomarker high-density lipoprotein ischemic stroke phosphorylatedα-synuclein poststroke cognitive impairment

非小细胞肺癌患者外周血中EGFR基因突变与埃克替尼治疗效果的相关性

在线全文

学校读者我要写书评

暂无评论

药物评价研究 2019年第5期42卷 949-951,955页

作者：李雅昆洛阳市第三人民医院呼吸内科河南洛阳471000

目的探讨非小细胞肺癌(NSCLC)患者外周血液中表皮生长因子受体(EGFR)基因突变与埃克替尼治疗效果的相关性。方法选取洛阳市第三人民医院自2014年2月—2018年2月收治的101例NSCLC患者作为实验对象,采用RT-PCR技术检测外周血液中EGFR基因... 详细信息

目的探讨非小细胞肺癌(NSCLC)患者外周血液中表皮生长因子受体(EGFR)基因突变与埃克替尼治疗效果的相关性。方法选取洛阳市第三人民医院自2014年2月—2018年2月收治的101例NSCLC患者作为实验对象,采用RT-PCR技术检测外周血液中EGFR基因突变情况,依据测定结果分为基因突变组和野生型组,均采用埃克替尼治疗分析其治疗效果;选取同期做健康体检的患者50例作为对照组,比较NSCLC患者与健康人外周血液中EGFR突变差异。结果 50例健康人外周血液检测EGFR基因突变率为0,NSCLC患者中EGFR基因突变率为41.58%(42例),EGFR野生型组患者31.68%(32例),EGFR基因未突变者27例。基因突变组患者疾病控制率为85.71%,治疗有效率为64.29%;野生型组疾病控制率为59.38%,总有效率仅为12.5%,数据差异有统计学意义(P<0.05)。随访6个月内两组患者生存率差异无统计学意义,随访1、2年间EGFR基因突变组的生存率均远高于野生型组,数据差异有统计学意义(P<0.05)。结论 NSCLC患者外周血中EGFR基因突变患者行埃克替尼治疗效果更高,因此在晚期的NSCLC患者治疗中可以通过测定是否EGFR基因突变来指导靶向药物治疗。

关键词：非小细胞肺癌表皮生长因子受体基因突变靶向治疗药物埃克替尼

康艾注射液联合盐酸埃克替尼片治疗晚期非小细胞肺癌的疗效观察

在线全文

学校读者我要写书评

暂无评论

药物评价研究 2019年第4期42卷 709-711,729页

作者：李雅昆洛阳市第三人民医院呼吸内科河南洛阳471000

目的探讨康艾注射液联合盐酸埃克替尼片治疗晚期非小细胞肺癌的临床疗效。方法选取2013年5月—2018年5月在洛阳市第三人民医院就诊的82例晚期非小细胞肺癌患者,随机分为观察组(n=41)和对照组(n=41)。对照组给予患者口服盐酸埃克替尼片,3... 详细信息

目的探讨康艾注射液联合盐酸埃克替尼片治疗晚期非小细胞肺癌的临床疗效。方法选取2013年5月—2018年5月在洛阳市第三人民医院就诊的82例晚期非小细胞肺癌患者,随机分为观察组(n=41)和对照组(n=41)。对照组给予患者口服盐酸埃克替尼片,3次/d,125 mg/次。观察组在对照组基础上给予康艾注射液40 mL,1次/d。两组均治疗1个月。对比两组治疗效果、生活质量和毒副作用发生率。结果与对照组治疗总有效率12.20%和病情控制率48.78%比较,观察组治疗总有效率31.71%和病情控制率85.37%均显著升高(P<0.05)。两组呼吸困难、便秘、食欲缺乏发生率,角色功能、认知功能、社会功能评分及毒副作用(肝功能异常和腹泻)发生率比较,差异均无统计学意义。观察组疲倦、疼痛和皮疹发生率均显著低于对照组(P<0.05);躯体功能、情绪功能评分均显著高于对照组(P<0.05)。结论康艾注射液联合盐酸埃克替尼片治疗晚期非小细胞肺癌疗效显著,且安全性良好,值得临床推广。

关键词：非小细胞肺癌康艾注射液盐酸埃克替尼

在线全文

学校读者我要写书评

暂无评论

电动拖拉机电子液压动力系统的设计与分析

农机化研究 2024年第5期46卷 251-256页

作者：李亚昆郑州工业应用技术学院郑州451100

电子液压技术已经成为目前工业发展、机械制造、国防科技中的不可缺少的核心技术,近年来已经逐步应用到农业机械生产制造中。拖拉机作为农业机械中的重要农机具,提高拖拉机的田间工作性能是提高各类农业生产的重要基础条件。为此,基于... 详细信息

电子液压技术已经成为目前工业发展、机械制造、国防科技中的不可缺少的核心技术,近年来已经逐步应用到农业机械生产制造中。拖拉机作为农业机械中的重要农机具,提高拖拉机的田间工作性能是提高各类农业生产的重要基础条件。为此,基于电子液压技术,研制一种农用拖拉机电子液压动力传动系统(MEH-PS),并根据拖拉机的实际工作要求选择了动力和传动部件,基于拖拉机仿真和试验模型分析了动力传动系统的速度特性、扭矩特性、功率分配特性和效率特性,以验证其在特定工况下的工作性能。仿真结果表明:基于电子液压动力系统下的拖拉机的加速性能得到改善,速度范围更广,动力元件和液压元件均满足要求,且HMT在较宽的速度范围内保持平均效率86%以上。系统试验结果表明:动力总成系统的无级调速特性和效率特性与仿真结果基本一致,可以满足农用拖拉机的工作性能与生产需求。

关键词：拖拉机电子液压系统设计仿真分析

维普期刊数据库博看期刊

膜式人工肺中空纤维膜材料的改善及发展新方向

在线全文

学校读者我要写书评

暂无评论

中国组织工程研究 2022年第16期26卷 2608-2612页

作者：李雅坤黑飞龙中国医学科学院阜外医院体外循环科北京市100037

背景:随着各种优质膜材料的相继出现,选择适宜的膜材料已成为人工肺技术开展的关键。通过物理或化学方法对膜材料表面进行改性处理以制备具有优良血液相容性和高气体交换率等优异性能的复合膜,是当下研究的热点问题。目的:从人工肺的发... 详细信息

背景:随着各种优质膜材料的相继出现,选择适宜的膜材料已成为人工肺技术开展的关键。通过物理或化学方法对膜材料表面进行改性处理以制备具有优良血液相容性和高气体交换率等优异性能的复合膜,是当下研究的热点问题。目的:从人工肺的发展过程出发,介绍目前常用的膜材料,并对当下提高膜材料血液相容性的研究成果进行综述,对未来改善膜式人工肺中空纤维膜材料的新方向提出展望。方法:检索Pub Med数据库、CNKI和万方数据库中已发表的与人工肺膜材料有关的文献,并对其进行阅读和筛选。英文检索词为"artificial lung;membrane artificial lung;oxygenator;hollow fiber membrane;polymer;blood compatibility";中文检索词为"人工肺;膜式人工肺;氧合器;中空纤维膜;高分子材料;血液相容性"。结果与结论:近年来,各类可以改善血液相容性的分子不断被研究者用来对膜式人工肺膜材料表面进行改性,肝素、亲水性分子(如聚乙二醇)、两性分子(如磷酰胆碱)等改性膜材料的研究相对比较成熟,已在临床得到广泛应用,其他改良措施(例如表面内皮化、NO释放中空纤维)也逐渐发展起来。然而,目前提高膜材料气体交换能力的研究较少,尤其是在氧合性能方面仍有继续完善优化的空间。未来人工肺膜材料的研究会朝着两个方向发展:一是开发混合型膜材料表面改性涂层,结合各类材料优势达到血液相容性最大化的目的;二是可以通过改善血流动力学、改进制膜工艺、物理或化学改性等方法提高膜材料的气体交换氧合性能及避免发生血浆渗漏。

关键词：人工肺膜式人工肺氧合器中空纤维膜高分子材料血液相容性