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Early Goal Directed Sedation, a bridge to better clinical outcomes

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Chinese Medical Journal 2014年第10期127卷 1969-1972页

作者： yahya Shehabi Univ New S Wales Sch Clin Randwick NSW 2301 Australia Monash Univ Fac Med Nursing & Hlth Sci Melbourne Vic 3004 Australia Prince Wales Hosp Randwick NSW 2031 Australia

Critical care has become a central part of modern medicine and an integral essential to improve the outcomes in acute *** increasing complexity of surgical procedures,severity of co-morbid diseases,life expectancy and societal expectation is likely to escalate the burden and the global need for critical care *** millions of patients are ventilated worldwide every year,projections suggest that the number of ventilated patients is expected to rise by 31% over the following decade.1

关键词： sedation early goal directed sedation ventilation critically ill dexmedetomidine

Adjuvant activity of Pasteurella multocida A strain,Pasteurella multocida B strain and Salmonella typhimurium bacterial DNA on cellular and humoral immunity responses against Pasteurella multocida specific strain infections in Balb/c mice

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Asian Pacific Journal of Tropical Medicine 2018年第5期11卷 336-341页

作者： Maryam Homayoon yahya Tahamtan Mohammad Kargar Seyed Mohammad Hossein Hosseini Abbas Akhavan Sepahy Department of Biology Science and Research BranchIslamic Azad University Department of Microbiology Shiraz BranchRazi Vaccine and Serum Research InstituteAgriculture ResearchEducation and Extension Organization Department of Microbiology Jahrom Branch Islamic Azad University Department of Microbiology Tehran North BranchIslamic Azad University

Objective: To evaluate the effects of Pasteurella multocida(P. multocida) vaccines on the expression and release of antibodies, interleukin(IL)-6 and IL-12 by serum. Methods: Balb/c mice were immunized with two formalin and iron inactivated vaccine doses within 2 weeks. The vaccines were adjuvant with P. multocida A strain, P. multocida B strain and Salmonella typhimurium bacterial DNA(AbDNA, BbDNA and SbDNA for short, respectively). The animals were challenged 4 weeks after immunization. Blood of mice was collected to detect the change of specific antibody, IL-6, and IL-12 using ELISA. Results: The specific antibody and interleukins in the immunized group increased significantly compared to the control mice after vaccination and challenge(P<0.05). The highest release of these cytokines was obtained by *** inactivated with iron and adjuvant with AbDNA at a concentration of 25 μg/mL. The antibody titer peak was 0.447 in mice vaccinated with iron-killed whole-cell antigen adjunct with AbDNA. The time-courses of release showed that bacterial DNA was able to stimulate IL-6 and IL-12 production more than alum(P<0.05). Conclusions: Our findings introduce that bacterial DNA is capable of releasing an immunological response with several *** indicate that bacterial DNA entrapped with killed P. multocida antigen is a new and effective adjuvant to enhance specific immunity and resistance of animal against the infectious pathogen, which could simplify the development of highly promising strong adjuvant.

关键词： Pasteurella multocida Bacterial DNA Adjuvant activity Vaccine Immunity Balb/c mice

Natural variants and editing events provide insights into routes for spike architecture modification in common wheat

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The Crop Journal 2023年第1期11卷 148-156页

作者： Min Fan Xiaoyu Zhang Ragupathi Nagarajan Wenxuan Zhai yahya Rauf Haiyan Jia Zhengqiang Ma Liuling Yan Crop Genomics and Bioinformatics Center and National Key Laboratory of Crop Genetics and Germplasm Enhancement Nanjing Agricultural UniversityJiangsuNanjing 210095JiangsuChina Department of Plant and Soil Sciences Oklahoma State UniversityStillwaterOK 74078USA

Spike architecture is an indicative trait of grain yield in common wheat(Triticum aestivum).A segregating population was generated for mapping genes contributing to spike morphometric traits by crossing the two common wheat cultivars'CItr 17600'with branching spikes and'Yangmai 18'with normal spikes.A major quantitative trait locus for spike length was mapped to the Q5A region of chromosome ***18 carried a Q5Ab allele for short spikes,which harbored one SNP in the last intron,and a 1-bp InDel in the 720-bp fragment from the start codon,compared to Q5Aa in Chinese *** 17600 harbored a q5Ab allele for long spikes,which has a 6-bp deletion compared to the reported q5Aa allele that was involved in the binding site of microRNA 172(miR172).This 6-bp deletion in immediately upstream of this binding site was involved in changes of four amino *** natural q5A allele appeared to be rare in common wheat but frequent in tetraploid *** accessions with branching *** CRISPR/Cas9 technology was used to edit the upstream region involving in the miR172 binding site in Yangmai 18 and identified two independent editing events,one with a 1-bp insertion in Q5A and the other with a 2-bp deletion in Q5D,resulting in several shapes of spikes in the transgenic *** addition to the effects of natural q5A allele and the edited Q5A genes,this study indicated the regeneratability and transformability of Yangmai 18 as an elite ***,this study provides insight into future modification and engineering of spike architecture in common wheat.

关键词： Q gene Spike shape miR172 Gene editing Wheat

Arterial complication of irreversible electroporation procedure for locally advanced pancreatic cancer

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World Journal of Gastrointestinal Oncology 2016年第10期8卷 751-756页

作者： yahya Ekici Tugan Tezcaner Hüseyin Onur Aydin Fatih Boyvat G?khan Moray Department of General Surgery Medical Faculty of Baskent University Department of Radiology Medical Faculty of Baskent University

Irreversible electroporation(IRE) is a non-thermal ablation technique used especially in locally advanced pancreatic carcinomas that are considered surgically *** present the first case of acute superior mesenteric artery(SMA) occlusion secondary to pancreatic IRE procedure that has not been reported before in the literature.A 66-year-old man underwent neoadjuvant chemoradiotherapy for locally advanced pancreatic ductal *** procedure was applied to the patient during laparotomy under general *** finishing the procedure,an acute intestinal ischemia was detected.A conventional vascular angiography was performed and a metallic stent was successfully placed to the SMA and blood flow was *** is important to be careful in such cases of tumor involvement of SMA when evaluating for IRE procedure of pancreatic tumor.

关键词： Irreversible electroporation Mesenteric artery occlusion Locally advanced pancreatic cancer Superior mesenteric artery

Isolation and identification of desert habituated arbuscular mycorrhizal fungi newly reported from the Arabian Peninsula

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Journal of Arid Land 2014年第4期6卷 488-497页

作者： Sarah SYMANCZIK Janusz BLASZKOWSKI Sally KOEGEL Thomas BOLLER Andres WIEMKEN Mohamed N AL-yahya'EI Zurich Basel Plant Science Center Institute of BotanyUniversity of Basel Department of Plant Protection West Pomeranian University of Technology Soil and Water Research Center. Ministry of Agriculture and Fisheries Department of Aridland Agriculture College of Food and AgricultureUnited Arab Emirates University

Arbuscular mycorrhizal fungi（AMF） are known to facilitate the growth and vigour of many plants, particularly in arid ecosystems. In a survey of AMF in a date palm plantation and two natural sites of a desert in Oman, we generated many single spore-derived cultures of AMF. We identified a number of these isolates based on spore morphotyping and molecular phylogenetic analysis using the sequence of the LSU-rDNA. Here, we presented the characteristics of four species of AMF recovered, namely Claroideoglomus drummondii, Diversispora aurantia, Diversispora spurca and Funneliformis africanum. The four species have been described previously, but for the Arabian Peninsula they are reported here for the first time. Our endeavor of isolation and characterization of some AMF habituated to arid sites of Arabia represents a first step towards application for environmental conservation and sustainable agriculture in this region.

关键词： arbuscular mycorrhizal fungi biotechnology isolation characterization desert ecosystem Arabian Peninsula Oman

Toward Optimal Cost-Energy Management Green Framework for Sustainable Future Wireless Networks

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Computers, Materials & Continua 2021年第7期68卷 1321-1339页

作者： Mohammed H.Alsharif Abu Jahid Mahmoud A.Albreem Peerapong Uthansakul Jamel Nebhen Khalid yahya Department of Electrical Engineering College of Electronics and Information EngineeringSejong UniversitySeoul05006Korea Department of Electrical and Computer Engineering University of OttawaOttawaK1N 6N5ONCanada Department of Electronics and Communications Engineering A’Sharqiyah UniversityIbra400Oman School of Telecommunication Engineering Suranaree University of TechnologyNakhon RatchasimaThailand College of Computer Engineering and Sciences Prince Sattam bin Abdulaziz UniversityAlkharj11942Saudi Arabia Department of Mechatronics Faculty of Engineering and ArchitectureIstanbul Gelisim UniversityIstanbul34310Turkey

The design of green cellular networking according to the trafc arrivals has the capability to reduce the overall energy consumption to a cluster in a cost-effective *** cell zooming approach has appealed much attention that adaptively ofoads the BS load demands adjusting the transmit power based on the trafc intensity and green energy ***,the researchers are focused on implementing renewable energy resources,which are considered the most attractive practices in designing energy-efcient wireless networks over the long term in a cost-efcient way in the existing *** utilization of available solar can be adapted to acquire cost-effective and reliable power supply to the BSs,especially that sunlight is free,available everywhere,and a good alternative energy option for the remote ***,planning a photovoltaic scheme necessitates viability assessment to avoid poor power supply,particularly for ***,cellular operators need to consider both technical and economic factors before the implementation of solar-powered *** paper proposed the usercentric cell zooming policy of solar-powered cellular base stations taking into account the optimal technical criteria obtained by the HOMER software *** results have shown that the proposed system can provide operational expenditure(OPEX)savings of up to 47%.In addition,the efcient allocation of resource blocks(RBs)under the cell zooming technique attain remarkable energy-saving performance yielding up to 27%.

关键词： Wireless networks beyond 5G green communications sustainability OPEX communication systems

Design of binder jet additive manufactured co-continuous ceramic-reinforced metal matrix composites

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Journal of Materials Science & Technology 2020年第14期47卷 81-90页

作者： Pablo D.Enrique Ehsan Marzbanrad yahya Mahmoodkhani Ali Keshavarzkermani Hashem Al Momani Ehsan Toyserkani Norman Y.Zhou University of Waterloo 200 University Ave WWaterlooOntarioN2L 3G1Canada

Ceramic-reinforced metal matrix composites(MMCs)display beneficial properties owing to their combination of ceramic and metal ***,the properties are highly dependent on the reinforcing phase composition,volume fraction and *** fiber or network reinforcement morphologies are difficult and expensive to manufacture,and the often-used discontinuous particle or whisker reinforcement morphologies result in less effective ***,we demonstrate the formation of a co-continuous ceramic-reinforced metal matrix composite using solid-state *** jet additive manufacturing(BJAM)was used to print a nickel superalloy part followed by post-processing via reactive sintering to form a continuous carbide reinforcing phase at the particle *** kinetics of reinforcement formation are investigated in order to develop a relationship between reactive sintering time,temperature and powder composition on the reinforcing phase thickness and volume *** evaluate performance,the wear resistance of the reinforced BJAM alloy 625 MMC was compared to unreinforced BJAM alloy 625,demonstrating a 64%decrease in the specific wear rate under abrasive wear conditions.

关键词： Binder jetting Reactive sintering Metal matrix composite Co-continuous composite Wear resistance

A Smart Heart Disease Diagnostic System Using Deep Vanilla LSTM

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Computers, Materials & Continua 2023年第10期77卷 1251-1279页

作者： Maryam Bukhari Sadaf Yasmin Sheneela Naz Mehr yahya Durrani Mubashir Javaid Jihoon Moon Seungmin Rho Department of Computer Science COMSATS University IslamabadAttock CampusAttockPakistan Department of Computer Science COMSATS University IslamabadIslamabadPakistan Department of Computer Science UET TaxilaTaxilaPakistan Department of AI and Big Data Soonchunhyang UniversityAsanKorea Department of Industrial Security Chung-Ang UniversitySeoul06974Korea

Effective smart healthcare frameworks contain novel and emerging solutions for remote disease diagnostics,which aid in the prevention of several diseases including heart-related *** this context,regular monitoring of cardiac patients through smart healthcare systems based on Electrocardiogram(ECG)signals has the potential to save many *** existing studies,several heart disease diagnostic systems are proposed by employing different state-of-the-art methods,however,improving such methods is always an intriguing area of ***,in this research,a smart healthcare system is proposed for the diagnosis of heart disease using ECG *** proposed framework extracts both linear and time-series information on the ECG signals and fuses them into a single framework *** linear characteristics of ECG signals are extracted by convolution layers followed by Gaussian Error Linear Units(GeLu)and time series characteristics of ECG beats are extracted by Vanilla Long Short-Term Memory Networks(LSTM).Following on,the feature reduction of linear information is done with the help of ID Generalized Gated Pooling(GGP).In addition,data misbalancing issues are also addressed with the help of the Synthetic Minority Oversampling Technique(SMOTE).The performance assessment of the proposed model is done over the two publicly available datasets named MIT-BIH arrhythmia database(MITDB)and PTB Diagnostic ECG database(PTBDB).The proposed framework achieves an average accuracy performance of 99.14%along with a 95%recall value.

关键词： Smart systems deep learning ECG signals heart disease concurrent learning LSTM generalized gated pooling

Security Requirement Management for Cloud-Assisted and Internet of Things—Enabled Smart City

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Computers, Materials & Continua 2021年第4期67卷 625-639页

作者： Muhammad Usman Tariq Muhammad Babar Mian Ahmad Jan Akmal Saeed Khattak Mohammad Dahman Alshehri Abid yahya Abu Dhabi School of Management Abu Dhabi6844United Arab Emirates Department of Computing and Technology Iqra UniversityIslamabad44000Pakistan Institute of Research and Development Duy Tan UniversityDa Nang550000Vietnam The Faculty of Information Technology Duy Tan UniversityDa Nang550000Vietnam Department of Computer Sciences Abdul Wali Khan UniversityMardan23200Pakistan Department of Computer Sciences Quaid-i-Azam UniversityIslamabad44000Pakistan Department of Computer Science College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia Botswana International University of Science and Technology Palapye016Botswana

The world is rapidly changing with the advance of information *** expansion of the Internet of Things(IoT)is a huge step in the development of the smart *** IoT consists of connected devices that transfer *** IoT architecture permits on-demand services to a public pool of *** computing plays a vital role in developing IoT-enabled smart *** integration of cloud computing enhances the offering of distributed resources in the smart *** management of security requirements of cloud-assisted IoT systems can bring about risks to availability,security,performance,condentiality,and *** key reason for cloud-and IoT-enabled smart city application failure is improper security practices at the early stages of *** article proposes a framework to collect security requirements during the initial development phase of cloud-assisted IoT-enabled smart city *** three-layered architecture includes privacy preserved stakeholder analysis(PPSA),security requirement modeling and validation(SRMV),and secure cloud-assistance(SCA).A case study highlights the applicability and effectiveness of the proposed framework.A hybrid survey enables the identication and evaluation of signicant challenges.

关键词： Security privacy smart city Internet of Things cloud computing