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Hematological Alterations in an Eastern Sudanese Chronic Kidney Disease Patient Population

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Open Journal of Urology 2024年第6期14卷 359-367页

作者： Mohammed Omer Abaker Gibreel Sundus Kamal ibrahim Wijdan Abdel Aziz Hassan Manar yahia Mahjoub Leyla Mohammed Kheir Hamid Hibatellah Majzoub Abbas Nuha Fouzi Mohammed Secretariat of Academic Affairs Port Sudan Ahlia University Port Sudan Sudan Department of Hematology and Immunohematology College of Graduate Studies Port Sudan Ahlia University Port Sudan Sudan

Background: Chronic Kidney Disease (CKD), associated with a slow and progressive loss of kidney function over a period of several years, is an important clinical disaster with an increasing rate of morbidity and mortality especially in the least developed countries. Many hematological parameters are thought to alter dramatically during the course of the disease. These include white blood cells, red blood cells, and platelets. Methods: We tried, retrospectively, to evaluate the peripheral blood hematological alterations in a group of patients undergoing hemodialysis in an eastern Sudan dialysis center to add local medical information. Results: Anemia (Low hemoglobin and hematocrit) was detected in 94% of the patients’ group. Mean Erythrocyte count (3.32vs.4.76 (×109/L)), Hemoglobin concentration (9.4vs.13 (g/dl)), Hematocrit (28.7vs.38.7 (L/L)) and platelet count (296 vs. 238 (×109/L)) were significantly lower in the patients’ group than in the control group (P-values Conclusion: Five out of eight studied parameters (Red cell count, hemoglobin, hematocrit, mean cell hemoglobin concentration, and platelets count) have shown a significant alteration in CKD patients. As the complete blood count (CBC) test is the most utilized test in clinical laboratory practice, these alterations may be considered as early indicators for CKD. Furthermore, all patients with CKD must be routinely checked for these alterations.

关键词： Chronic Kidney Disease Chronic Renal Failure Hematological Alterations CBC Eastern Sudan Hemodialysis

New Decision-Making Technique Based on Hurwicz Criteria for Fuzzy Ranking

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Computers, Materials & Continua 2022年第12期73卷 4595-4609页

作者： Deepak Sukheja Javaid Ahmad Shah G.Madhu K.Sandeep Kautish Fahad A.Alghamdi ibrahim.S.yahia El-Sayed M.El-Kenawy Ali Wagdy Mohamed Department of Computer Science and Engineering VNR Vignana Jyothi Institute of Engineering and TechnologyHyderabadIndia Department of Mathematics Dr.APJ Abdul Kalam University Indore(M.P)India Department of Information Technology VNR Vignana Jyothi Institute of Engineering and TechnologyHyderabadIndia LBEF Campus Kathmandu44600Nepal Department of Management Information Systems College of Applied Studies and Community ServiceImam Abdulrahman Bin Faisal UniversityDammamSaudi Arabia Laboratory of Nano-Smart Materials for Science and Technology(LNSMST) Department of PhysicsFaculty of ScienceKing Khalid UniversityP.O.Box 9004Abha 61413Saudi Arabia Research Center for Advanced Materials Science(RCAMS) King Khalid UniversityP.O.Box 9004Abha 61413Saudi Arabia Nanoscience Laboratory for Environmental and Biomedical Applications(NLEBA) Semiconductor Lab.Department of PhysicsFaculty of EducationAin Shams UniversityRoxyCairo 11757Egypt Department of Communications and Electronics Delta Higher Institute of Engineering and TechnologyMansoura35111Egypt Faculty of Artificial Intelligence Delta University for Science and TechnologyMansoura35712Egypt Operations Research Department Faculty of Graduate Studies for Statistical ResearchCairo UniversityGiza12613Egypt Department of Mathematics and Actuarial Science School of Sciences Engineering The American University in CairoEgypt

Efficient decision-making remains an open challenge in the research community,and many researchers are working to improve accuracy through the use of various computational *** this case,the fuzzification and defuzzification processes can be very *** is an effective process to get a single number from the output of a fuzzy *** defuzzification as a center point of this research paper,to analyze and understand the effect of different types of vehicles according to their *** this paper,the multi-criteria decision-making(MCDM)process under uncertainty and defuzzification is discussed by using the center of the area(COA)or ***,to find the best solution,Hurwicz criteria are used on the defuzzified ***-making technique is proposed using Hurwicz criteria for triangular and trapezoidal fuzzy *** proposed technique considers all types of decision makers’perspectives such as optimistic,neutral,and pessimistic which is crucial in solving decisionmaking problems.A simple case study is used to demonstrate and discuss the Centroid Method and Hurwicz Criteria for measuring risk attitudes among *** significance of the proposed defuzzification method is demonstrated by comparing it to previous defuzzification procedures with its application.

关键词： Defuzzification decision-making fuzzy numbers Hurwicz multicriteria decision-making ranking order

The Frequency of the v-AKT Murine Thymoma Viral Oncogene Homologue 1 Gene Amplification among Sudanese Women with Ovarian Cancer: A Cross-Sectional Study

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Open Journal of Genetics 2023年第2期13卷 75-82页

作者： Rawia Eljaili Elmassry Aisha Osman Mohammed Amina ibrahim Badawy Rasha Saad Abdalhamid Huda Abdalla Eltahir Safa Abass Mohammed Hammad yahia Abdou Adil Abdelrahim Yousif Zubaida Abohumeda Adam Nazik Elmalaika Husaim College of Health Sciences and Nursing Al-Rayan Colleges Al Madinah Al Munawwarah Kingdom of Saudi Arabia Faculty of Medical Laboratory Sciences Alzaiem Alazhari University Khartoum Sudan College of Applied Medical Sciences King Khalid University Abha Kingdom of Saudi Arabia Faculty of Medicine Omdurman Islamic University Khartoum Sudan

Background: Protein kinase B (AKT/PKB) family is frequently amplified in ovarian cancer (OC). To the greatest of our knowledge, there is a lack of published reports about the amplification of the genes belonging to the AKT family among Sudanese women with OC. The present study was conducted to detect the AKT1 gene amplification and its association with tumour types, grades, and ages among Sudanese women with OC, bearing in mind the ethnic variation. Methods: This institution-based study included 79 cases of women diagnosed with ovarian cancer (OC) at Omdurman Maternity Hospital in the period 2013-2018. Formalin-fixed, paraffin-embedded (FFPE) tissue sections were used to extract RNA. AKT1 gene amplification was assessed using quantitative real-time PCR. Results: The mean age (±SD) of included women was 49.29 (±13.612). The amplification of AKT1 gene was observed in 18/79 (22.8%) of OC women, with a high frequency in women with undifferentiated 1/2 (50%), clear cell 2/6 (33.3%), mucinous 3/11 (27.3%), endometrioid 3/17 (17.6%), and serous carcinomas 5/30 OC (16.7%). High frequency was seen in women with low (26.3%;n = 10/28) rather than in higher (19.5%;n = 8/33) grade carcinoma, and in older (25.8%;n = 8/23) rather than younger (18.2%;n = 2/9) women. No significant association between AKT1 gene amplification and tumour types, grades, and ages of women was observed (Fisher’s Exact test: p = 0.405, 0.593 and 0.851, respectively). Conclusion: AKT1 gene amplification arises in around one-fifth of Sudanese women with ovarian cancer (OC). It is seen more in undifferentiated, clear cell, and mucinous tumours types, and more frequently in low tumour grade and older women, but not to a statistically significant level. These outcomes sustenance previous studies suggesting that activated AKT genes have a vital role in OC progression and may offer a plan for targeted therapy and prognostic evaluation.

关键词： AKT1 Gene Amplification Ovarian Cancer Cross-Sectional Study Quantitative Real-Time PCR Sudan

Assessment of undergraduate students’ tooth preparation for full veneer cast restorations

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Open Journal of Stomatology 2014年第2期4卷 43-48页

作者： Nuha El-Mubarak Neamat Abu-Bakr Osama Omer yahia ibrahim Department of Oral Rehabilitation Faculty of Dentistry University of Khartoum Khartoum Sudan Department of Restorative Dentistry and Periodontology Dublin Dental School and Hospital Dublin Ireland

Purpose: To evaluate tooth preparation for full veneer cast restorations performed by final year dental students in Sudan. Materials and Methods: 117 stone dies from two different dental institutions were collected and evaluated. Polyvinylsilioxane impression material was used to produce two impressive replicas of which one was sectioned in faciolingual plane and the other in mesiodistal plane. Occlusal clearance was measured using a digital caliper. Amount of axial preparation was also measured. Impression silhouettes that were produced using an overhead projector were used to measure convergence angle. Working casts were examined for smoothness and evenness of the preparations, existence or absence of additional features of retention and the finishing line were evaluated for its position and continuity. All obtained data were statistically analyzed by using T-test, ANO-VA, and Pearson Chi square tests. P-values ≤ 0.05 were considered as statistically significant. Results: Average taper of the examined preparations was 39.98?, with 44.1? in the faciolingual, and 35.8? in the mesiodistal dimensions. Preparations for full coverage restorations were over prepared. 38.5% of the total number of preparations were found to have finishing lines in the sub and supra gingival positions. 19.66% were unable to maintain continuity of the finishing line all around the preparation. All preparations were generally smooth with no sharp angles, and 1.7% of the preparations had additional retentive features. Conclusion: Within the limitations of this study, it could be concluded that the convergence angle and finishing line preparations were less than adequate in a sizeable proportion of the preparations examined.

关键词： Fixed Prosthodontics Tooth Preparation Finish Lines ImpressionsFixed Prosthodontics Impressions

Regular and Irregular Sampling Linear Transforms in Series of Shift-Invariant Spaces

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Journal of Mathematics and System Science 2020年第1期10卷 22-27页

作者： Adam Zakria Ahmed yahia ibrahim Elkhalil Hosam Alfadel Department of Mathematics Jouf University College of Sciences and ArtsKingdom of Saudi Arabia Department of Mathematics Faculty of ScienceUniversity of KordofanSudan Department of Mathematics Faculty of ScienceShendi UniversitySudan

In this article we show that there exists an analogue of the Fourier duality technique in the setting a series of shift-invariant ***,every a series shift-invariant spaceΣ^𝑛𝑖=1𝑉𝜙𝑖𝑖with a stable generator^𝑛𝑖=1𝜙𝑖is the range space of a bounded one-to-one linear operator𝑇𝑇between𝐿𝐿2(0,1)and𝐿𝐿2(R).We show regular and irregular sampling formulas inΣ𝑛𝑛𝑖𝑖=1𝑉𝑉𝜙𝜙𝑖𝑖are obtained by transforming.

关键词： Shift-invariant spaces sampling expansions zak transform

Ulcerated Lesion in Buccal Mucosa in a Patient with Paracoccidioidomycosis——Case Report

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Journal of Biosciences and Medicines 2017年第10期5卷 44-50页

作者： Giovanna Lima Vaz Livia Cristina de Melo Pino Aline Gabriela Santos Costa ibrahim yahia El Somailli Joao Roberto Resende Fernandes Elayne Christina Meireles Martins Daniel Cohen Goldemberg Aline Hellen da Silva Camacho Rhanna Neves Cirqueira Daniel Almeida da Costa College of Medicine of Valenca—FAA/Cesva ValencaBrazil National Cancer Institute—INCA Rio de JaneiroBrazil Centro Universitario de Belo Horizonte-UNIBH Belo HorizonteBrazil

Paracoccidioidomycosis is the most prevalent systemic mycosis in Latin America. It is a fungal infection caused by the dimorphic fungus Paracoccidioides brasiliensis. This microorganism can penetrate the human body through direct contact and can cause intense lymphadenopathy, ulcerated lesions in the oral cavity and in the skin among other alterations. In this study, we report a case of paracoccidioidomycosis with unusual clinical presentation, as it manifested in the female sex and although it did not present any relevant complaints of respiratory focus, it presented a single ulcerated lesion in the buccal mucosa. A biopsy of the lesion and a mycological examination revealed Paracoccidioidesbrasiliensis infection.

关键词： Paracoccidioidomycosis Paracoccidioides brasiliensis Endemic Mycosis