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SArS-CoV-2 in inflammatory bowel disease population:Antibodies,disease and correlation with therapy

World Journal of Gastrointestinal Endoscopy 2022年第3期14卷 153-162页

作者： Clara Benedetta Conti Elsa Mainardi Sara soro Sophie Testa Annalisa De Silvestri Andrea Drago Fabrizio Cereatti roberto Grassia Department of Gastroenterology and Digestive Endoscopy ASST CremonaCremona 26100Italy Department of Laboratory Medicine Haemostasis and Thrombosis CenterASST CremonaCremona 26100Italy Department of Clinic Epidemiology and Biometric Scientific DirectionFondazione IRCCS Policlinico San MatteoPavia 27100Italy

BACKGrOUnD Guidelines recommend to cease inflammatory bowel disease(IBD)biologic therapy during coronavirus disease 2019(COVID-19).AIM To investigate severe acute respiratory syndrome coronavirus 2(SArS-CoV-2)antibody positivity in an IBD cohort,COVID-19 disease severity and to evaluate the correlation with clinical/therapeutic *** Prospective observational cohort *** patients were tested for SArS-CoV-2 *** on COVID-19 disease,demographics/therapeutics and clinical features of the IBD population were ***≥7 was set for SArS-CoV-2 antibody *** swab was performed in cases of IgG *** between antibody positivity or COVID-19 symptoms and therapeutic/clinical data were *** In total,103 IBD patients were *** them,18.4%had IgG≥*** analysis of antibody positivity correlated only with IBD *** IgG≥7,the odds ratio was 1.44 and 0.16 for azathioprine and mesalazine,respectively,vs biologic drugs(P=0.0157 between them).COVID-19 related symptoms were reported in 63%of patients with IgG *** but one patient with COVID-19 symptoms did not require ceasing IBD treatment or hospitalization. IBDtreatment and body mass index correlated with COVID-19 disease development with *** IBD population does not have a higher risk of severe COVID-19. The relative risk of havingSArS-CoV-2 antibodies and symptoms was higher for patients taking azathioprine, then biologictherapy and lastly mesalazine. none of the patients under biologic therapy developed severeCOVID-19.

关键词： Inflammatory bowel disease SArS-CoV-2 COVID-19 Biologic treatment SArS-CoV-2 antibody Inflammatory bowel disease therapy

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俄罗斯东部中—新生代构造和矿床建造

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国外矿床地质 1995年第4期 41-42页

作者： soro.,AP 董建华

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Pancreatic Cancer: Epidemiological, Clinical and Therapeutic Aspects in Abidjan (Ivory Coast)

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Open Journal of Gastroenterology 2017年第8期7卷 223-229页

作者： Amadou Ouattara Siaka Kone Dramane soro Constant Assi Emile Allah-Kouadio rodrigue Irie Gohi Bi Fanoucoffi Denis Marie-Jeanne Lohoues-Kouacou Teaching Hospital Center of Cocody Abidjan C&ocirc te d’Ivoire

Aim: The aim was to study the epidemiological, clinical and therapeutic aspects of pancreatic cancers in Ivory Coast. Materials and methods: A retrospective multi-center and multidisciplinary study aimed at describing sixteen years and four months from January 1, 2000 to April 30, 2016 in several hospitals in the city of Abidjan taking charge of pancreatic cancers (hepato-gas troenterology services of the universities hospitals of Cocody and Yopougon), internal medicine departments of University Hospital of Treichville and Abidjan Military Hospital, the department of oncology of the university hospital center of Treichville, private clinics (DAnGA, PISAM and GMP), the COBA center in Treichville. The diagnosis of cancer was based on either histological criteria or a set of clinical and paraclinical arguments. Patients whose files did not include imaging were excluded from this study. The following parameters were collected: age, sex, reason for consultation, physical signs, personal and family antecedents, tumor characteristics, delay in diagnosis and the nature of the treatment administered. results: We have observed 150 cases of pancreatic cancer. The mean age of patients was 59.09 years with extremes ranging from 24 years to 88 years. Our study population consisted of 98 men and 52 women (sex ratio 1.88). risk factors were dominated by diabetes 20.7%. Epigastralgia is the main reason for consultation (48%). The tumor was localized at the cephalic level in 84.67%. In 13 cases the diagnosis was histological and was dominated by adenocarcinoma (100%). The majority of our patients was seen at an advanced stage of the disease: stage IV (74.56%). The average time to diagnosis was 2.76 months. Fourteen of our patients (9.33%) had benefited surgery. This was curative surgery in 35.71% (n = 5) and palliative in 64.29% (n = 9). Among those who benefited from this curative surgery, three died two months after surgery and two lost to follow-up. The majority (90.67%) of our pa

关键词： Pancreas Cancer Epidemiological Ivory Coast

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Endoscopic ultrasound diagnostic gain over computed tomography and magnetic resonance cholang-iopancreatography in defining etiology of idiopathic acute pancreatitis

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World Journal of Gastrointestinal Endoscopy 2022年第6期14卷 376-386页

作者： Stefano Mazza Biagio Elvo Clara Benedetta Conti Andrea Drago Maria Chiara Verga Sara soro Annalisa De Silvestri Fabrizio Cereatti roberto Grassia Gastroenterology and Digestive Endoscopy Unit ASST CremonaCremona 26100Italy Gastroenterology and Endoscopy Unit Federico Ⅱ UniversityNapoli 80131Italy Interventional Endoscopy Unit ASST MonzaMonza 20900Italy Biometry and Clinical Epidemiology Scientific DirectionIRCCS San Matteo Hospital FoundationPavia 27100Italy Department of Gastroenterology and Digestive Endoscopy Castelli HospitalAriccia(Rm)00040Italy

BACKGrOUnD About 10%-30%of acute pancreatitis remain idiopathic(IAP)even after clinical and imaging tests,including abdominal ultrasound(US),contrast-enhanced computed tomography(CECT)and magnetic resonance cholangiopancreatography(MrCP).This is a relevant issue,as up to 20%of patients with IAP have recurrent episodes and 26%of them develop chronic *** data are available on the role of EUS in clarifying the etiology of IAP after failure of one or more cross-sectional *** To evaluate the diagnostic gain after failure of one or more previous crosssectional *** We retrospectively collected data about consecutive patients with AP and at least one negative test between US,CECT and MrCP,who underwent linear EUS between January 2017 and December *** investigated the EUS diagnostic yield and the EUS diagnostic gain over different combinations of these crosssectional imaging techniques for the etiologic diagnosis of *** and frequency of EUS diagnosis were also analyzed,and EUS diagnosis was compared with the clinical *** EUS,patients were followed-up for a median of 31.5 mo to detect cases of pancreatitis *** We enrolled 81 patients(63%males,mean age 61±18,23%with previous cholecystectomy,17%with recurrent pancreatitis).Overall EUS diagnostic yield for AP etiological diagnosis was 79%(20%lithiasis,31%acute on chronic pancreatitis,14%pancreatic solid or cystic lesions,5%pancreas divisum,5%autoimmune pancreatitis,5%ductal abnormalities),while 21%remained ***,CECT and MrCP,taken alone or in combination,led to AP etiological diagnosis in 16(20%)patients;among the remaining 65 patients,49(75%)obtained a diagnosis at EUS,with an overall EUS diagnostic gain of 61%.Sixty-eight patients had negative US;among them,EUS allowed etiological diagnosis in 59(87%).Sixty-three patients had a negative CECT;among them,47(74%)obtained diagnosis with ***-four had a negative MrCP;among them,20(83%)had EUS diag

关键词： Endoscopic ultrasound Idiopathic acute pancreatitis Diagnostic gain Computed tomography Magnetic resonance cholangiopancreatography

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Mapping of Malaria risk related to Climatic and Environmental Factors by Multicriteria Analysis in the Marahouéregion of Côte d’Ivoire

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Journal of Geoscience and Environment Protection 2022年第6期10卷 234-252页

作者： Assikohon Pulchérie Gouzile Martial Bama Bi Yourou Guillaume Zamina Ellélé Aimé Yapi Gneneyougo Emile soro Bi Tie Albert Goula Tiembré Issiaka national Institute of Public Hygiene Abidjan C&#244 te d’Ivoire Félix Houphouë t Boigny University Abidjan C&#244 te d’Ivoire nangui-Abrogoua University Abidjan C&#244 te d’Ivoire

Malaria, a febrile human disease transmitted by female anopheles whose ecology is linked to water, is a major public health problem in Côte d’Ivoire, more precisely in the Marahoué region located in the southwest of the country. In order to effectively control this disease, it is necessary to understand the etiology and the diffusion pattern of the vectors. This justifies this study, which proposes to determine the areas at risk of malaria transmission in order to carry out an effective fight against this disease in this region of Côte d’Ivoire. To achieve this, a combined approach of geographic information systems and multicriteria analysis was adopted. The analysis reveals that the south and northwest of the Marahoué region present a high risk for malaria transmission. This risk is linked to indicators such as climatic factors that cover 48.36% of the study area, environmental factors such as vegetation cover (nDVI), soil moisture (nDWI), altitude, hydrography (water point) and population that covers 55.29% of the area and land use. Also, the results indicated that 50.70% of the region has favorable conditions for malaria transmission. Overall, climatic and environmental indicators are the risk factors associated with the resurgence of malaria.

关键词： Mapping Palustrum Multicriteria Analysis Marahoué Ivory Coast

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Incorporation of Crop residues into Soil: A Practice to Improve Soil Chemical Properties

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Agricultural Sciences 2020年第12期11卷 1186-1198页

作者： Sifolo S. Coulibaly Mamadou Touré Amoin E. Kouamé Ini C. Kambou Sientchon Y. soro Kadokan I. Yéo Sita Koné Department of Biological Sciences University Peleforo Gon Coulibaly of Korhogo Korhogo C&#244 te d’Ivoire Laboratory of Ecology and Sustainable Development University of Nangui Abrogoua Abidjan C&#244 te d’Ivoire

Crop residues have the potential to enhance soil fertility, but this is dependent on their biochemical properties. This study aimed to evaluate the chemical composition, and nutrients release patterns of selected crop residues (corn stalk, rice straw, millet straw and sorghum stalk). Thus, 20 g of each crop residue were put in litter bags and placed in a plastic pot containing 10 kg of soil with a moisture content of 40% - 60%. Five replications were considered per type of residue and some samples were taken every 4 weeks. results showed that crop residues got a pH varying between 5.09 and 6.5. The lowest C content (33.11%) and nitrogen (0.27%) were measured in sorghum stalk when the highest C content (47.6%) and nitrogen content (0.55%) were registered in corn stalk. The highest phosphorus content (0.58%) was got in corn stalk. Potassium content was higher in millet straw than in others. The highest calcium content (0.37%) and magnesium (0.29%) were found in rice straw. There was an increase of soil chemical composition after crop residues burial. Significant increase in carbon, nitrogen, and phosphorus content was noted in soil at week 4 with the highest at week 16. At the end of the experiment, the highest C content (53.1%) and the highest nitrogen content (0.88%) in the soil were observed after burial of rice straw. The highest phosphorus content (0.82%) registered in the soil was got with millet straw. nutrient release efficiency of crop residues occurred in the following order: rice straw > millet straw > sorghum stalk > corn stalk. This study has demonstrated that rice straw and millet straw released nutrients faster and this is beneficial for early planted crops, while sorghum stalk and corn stalk released nutrients slowly which is appropriate for long-term availability of plant nutrients.

关键词： Crop residues Burial nutrient release

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Duodenal Metastases of Malignant Melanoma: One Case report

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Open Journal of Gastroenterology 2015年第8期5卷 111-114页

作者： soro Dramane Ouattara Amadou Okon Anassi Jean Baptiste Koné Siaka Assi Constant Allah-Kouadio Emile n’dah K. Justin ndjitoyap ndam Antonin Wilson Diallo Djeinabou Lohoues-Kouacou Marie Jeanne d’Arc Camara Benoit Mathieu Service d’Hépato-Gastroentérologie CHU Cocody Abidjan Cote d’Ivoire Service d’Hépato-Gastroentérologie CHU Bouaké Bouaké Cote d’Ivoire Service d’Anatomie Pathologique CHU Cocody Abidjan Cote d’Ivoire

The duodenal metastases of a malignant melanoma are rare. We report a case at a 86-year-old, hypertense patient, without tumoral history, who was hospitalized in our department for a change of the general state and an anaemia ferriprive without found home (foyer) of display. In the clinical examination, we had found anemia syndrome, nodules under cutaneous about 2 cm in diameter at the level of the thorax, of the belly, the members and of the lower lip partners in a painless left adenopathy axillary about 3 cm in diameter and an absence of méléna in the rectal touch. The gastroscopy had highlighted polypoides ulcéro-bourgeonnantes hurts with a blackish pigmentation by places at the level of the bulb and of the second duodenum. In the histology of biopsie fragments, we noted a fuso-cellular proliferation and epithelioid with deposits of melanin. The positivity of antibodies anti-protein S100 and anti HMB45 in the immunohistochemical study allowed confirming the diagnosis. The gastroduodenal hurts, persons suffering from a liver complaint and lungworts in the scanner testify of a terminal metastatic scattering. The death arose two months later, in a picture of circulatory collapse further to a high digestive bleeding of big abundance.

关键词： Duodenal Metastases Malignant Melanoma

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Effect of alcohol consumption on liver stiffness measured by transient elastography

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World Journal of Gastroenterology 2013年第4期19卷 516-522页

作者： Edouard Bardou-Jacquet Ludivine Legros Draman soro Marianne Latournerie Anne Guillygomarc'h Caroline Le Lan Pierre Brissot Dominique Guyader romain Moirand Hepatology and Addictology Department University Hospital PontchaillouF35000 RennesFrance Institut national de la Santé et de la recherche Médicale U991 Institut Fédératif de Recherche 140University of Rennes 1F35000 RennesFrance

AIM:To determine the evolution of transient elastography(TE) in patients with alcoholic liver disease according to alcohol cessation or ***:We retrospectively selected in our local database all patients who had two TE between June 2005 and november 2010 with chronic alcohol excessive consumption and excluded those with associated cause of liver *** was performed at least one week apart by senior *** examinations with less than ten successful measures or with an interquartile range above 30% were *** retrospectively reviewed file of all patients to include only patient followed up by trained addictologist and for which definite information on alcohol consumption was *** biological parameters [aspartate amino transferase(AST),alanine amino transferase and gamma-glutamyl transpeptidase(GGT)] within 4 wk of initial and final TE were *** fibrosis score according to initial and final TE were determined with available cut-off for alcoholic liver disease and hepatitis *** and final putative fibrosis score were compared according to alcohol consumption during ***:During the study period 572 patients had TE examination for alcoholic liver disease and 79 of them had at least two ***-seven patients met our criteria with a median follow-up of 32.5 *** the end of the study,13(35%) were abstinent,and 24(65%) *** patients had liver biopsy during *** decreased significantly during follow-up in 85% of abstinent patients [median(range):-4.9(-6.1,-1.9)],leading to a modification of the putative fibrosis stage in 28%-71% of patient according to different cut-off *** relapsers TE increased in 45% and decreased in 54% of *** was no statistical difference between initial and final TE in *** the overall population,using 22.6 kPa as cut-off for cirrhosis,4 patients had cirrhosis at initial TE and 3 patients had cirrhosis at final ***

关键词： Alcohol Transient elastography Cirrhosis Fibrosis Liver biopsy Liver stiffness

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Screening for Hepatitis B and C in Occupational Settings: Cross-Sectional Study about 4268 Corporates Agents in Cote d’Ivoire

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Open Journal of Gastroenterology 2017年第3期7卷 89-95页

作者： Constant Assi Amadou Ouattara Siaka Kone Dramane soro Emile Allah-Kouadio Claude Ghislain Kouakou nigué Luc Benoit-Mathieu Camara Marie-Jeanne Lohoues-Kouacou Teaching Hospital Center of Cocody Abidjan Cote d’Ivoire

Aim: To screen hepatitis B and C in occupational setting. Methods: Cross-sectional study multicenter in 16 enterprises (one occupational exposure;5602 agents). Screening was preceded by information, sensibilisation and informed consenting physician labor, labor union and agents. Hepatitis B surface antigen (HBsAg) and antibodies anti-hepatitis C (Elisa, third generation) were tested in all. For those with HBsAg positive, this test was completed by IgM and IgG, anti HBc, HBeAg, antibodies anti HBe, transaminases and HBB DnA;for those with positive anti-VHC antibodies, test was completed by transaminases and VHC’s rnA. results: rate of participation was 76.2% (4268/5602 labors). HBsAg or hepatitis C antibodies were positives in 425 (9.9%) of cases (HBsAg positive: 8.48%;Hepatitis C Antibodies positives: 1.50%;both: 0.05%). In HBsAg positive, viral replication and cytolysis were seen respectively in 2.5 % and 18.2%. According with transaminases, serologic markers and viral load, immunotolerance, inactive and immuno active phase were suspected in 0.56%, 80.9% and 1.6% of cases. In hepatitis C antibodies positives persons, any had viral replication but cytolysis was observed in 33.3% (n = 21). HBsAg was significantively (p r in exposed occupational enterprise versus non-occupational setting (14.4% vs 7.8%). They were no differences (p = 0.71) about hepatitis C antibodies in the two setting (1.8% vs 1.7%). Conclusion: Prevalence of HBsAg and hepatitis C antibodies was high in occupational setting in hepatitis endemic country. It’s important to screen all of person in these setting with no consideration with blood exposed or not exposed enterprise.

关键词： Hepatitis B and C Screening Occupational Setting Blood Exposed Enterprise

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recent Traumatic Dislocations of the Shoulder in Adults: Epidemiological, Therapeutic and Evolutionary Aspects

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Open Journal of Orthopedics 2023年第7期13卷 267-274页

作者： Inza Bamba Achié Jean-régis Akobe Kouamé Jean-Eric Kouassi Serge Amos Ekra Aya natacha Adélaide Kouassi Sédi Louess De randolphe Akpro Ibrahim Soumahoro Zolopégué Marcel soro Gbale Yannick Ble Koffi Léopold Krah Michel Kodo Traumatology and Orthopaedic Surgery Department of The University Hospital of Bouaké Alassane Ouattara University Bouaké C&ocircte d’Ivoire General Surgery Department of The University Hospital of Bouaké Alassane Ouattara University Bouaké C&ocircte d’Ivoire

Introduction: Shoulder dislocations represent about 50% of all joint dislocations. The objective was to describe the epidemiological, therapeutic and evolutionary aspects of traumatic shoulder dislocations in Bouaké. Methods: This retrospective and descriptive study was conducted between January 2017 and December 2019. It concerned patients over 15 years of age with a recent traumatic shoulder dislocation treated and followed in the department. The variables studied were epidemiological, therapeutic and evolutionary. The severity of the trauma was assessed according to the Injury Severity Score (ISS). Functional outcome was assessed according to the Constant score. results: There were 49 patients (49 dislocations) out of 22,569 patients. The prevalence was 0.2%. The mean age was 32 years (17 - 62). There were 38 men (77.5%). The sex ratio was 3.4. Students predominated (n = 10;20.4%). The etiology was dominated by road traffic accidents (n = 19;38.8%). Anterior dislocation was the most common (n = 45;92%). The ISS score was minor (n = 46;93.8%). The mean time to reduction was 7 hours (4 - 16). Orthopaedic reduction using the Kocher technique predominated (n = 44;89.8%). The mean duration of external rotation immobilisation of the shoulder was 23 days (16 - 45). recurrence occurred in 8 patients (21.6%). The functional outcome at a mean Constant follow-up of 15 months (8 - 20) was satisfactory (n = 44;89.8%). Conclusion: Traumatic dislocation of the shoulder represented 0.2%. Treatment was mainly orthopaedic. recurrence was rare.

关键词： Adult Shoulder Anterior Dislocation Traumatic Orthopaedic Treatment

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