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Effects of intensive psychological intervention on treatment compliance,psychological status,and quality of life of patients with epilepsy

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World Journal of Psychiatry 2024年第5期14卷 670-677页

作者： Su-Hua Zhang Jie-Hua Wang Hong-Yu Liu Yue-xia Zhang ya-Ling Lin bi-Yu Wu Department of Neurology Quanzhou First HospitalQuanzhou 362000Fujian ProvinceChina Department of Nursing Quanzhou First HospitalQuanzhou 362000Fujian ProvinceChina

BACKgROUND Epilepsy is a nervous system disease characterized by recurrent attacks,a long disease course,and an unfavorable *** is associated with an enduring therapeutic process,and finding a cure has been *** with epilepsy are predisposed to adverse moods,such as resistance,anxiety,nervousness,and anxiety,which compromise treatment compliance and overall *** To explored the influence of intensive psychological intervention on treatment compliance,psychological status,and quality of life(QOL)of patients with *** The clinical data of 105 patients with epilepsy admitted between December 2019 and July 2023 were retrospectively analyzed,including those of 50 patients who underwent routine intervention(control group)and 55 who underwent intensive psychological intervention(research group).Treatment compliance,psychological status based on the Self-Rating Anxiety Scale(SAS)and Depression Scale Self-Rating Depression Scale(SDS)scores,hope level assessed using the Herth Hope Scale(HHS),psychological resilience evaluated using the Psychological Resilience Scale,and QOL determined using the QOL in Epilepsy-31 Inventory(QOLIE-31)were comparatively *** Treatment compliance in the research group was 85.5%,which is significantly better than the 68.0%of the control *** notable intergroup differences in preinterventional SAS and SDS scores were identified(P>0.05);however,after the intervention,the SAS and SDS scores decreased significantly in the two groups,especially in the research group(Pgroups also exhibited no significant differences in preinterventional HHS,Connor-Davidson Resilience Scale(CD-RISC),and QOLIE-31 scores(P>0.05).After 6 months of intervention,the research group showed evidently higher HHS,CD-RISC,tenacity,optimism,strength,and QOLIE-31 scores(Pgical intervention enhances treatment compliance,psychological status,and QOL of patients with epilepsy.

关键词： Intensive psychological intervention Epilepsy Treatment compliance Psychological status Quality of life

Alcohol solvent effect on the self-assembly behaviors of lignin oligomers

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green Energy & Environment 2024年第4期9卷 597-603页

作者： ya Ma Zhicheng Jiang yafei Luo Xingjie guo Xudong Liu Yiping Luo bi Shi College of biomass Science and Engineering Sichuan UniversityChengdu610065China National Engineering Research Center of Clean Technology in Leather Industry Sichuan UniversityChengdu610065China College of Pharmacy(International Academy of Targeted Therapeutics and Innovation) Chongqing University of Arts and SciencesChongqing402160China State Key Laboratory of Utilization of Woody Oil Resource Hunan Academy of ForestryChangsha410004China CAS Key Laboratory of Environmental and Applied Microbiology Environmental Microbiology Key Laboratory of Sichuan ProvinceChengdu Institute of BiologyChinese Academy of SciencesChengdu610041China

The interactions between lignin oligomers and solvents determine the behaviors of lignin oligomers self-assembling into uniform lignin nanoparticles(LNPs).Herein,several alcohol solvents,which readily interact with the lignin oligomers,were adopted to study their effects during solvent shifting process for LNPs’*** lignin oligomers with widely distributed molecular weight and abundant guaiacyl units were extracted from wood waste(mainly consists of pine wood),exerting outstanding self-assembly *** and spherical LNPs were generated in H_(2)O-n-propanol cosolvent,whereas irregular LNPs were obtained in H_(2)O-methanol *** unsatisfactory self-assembly performance of the lignin oligomers in H_(2)O-methanol cosolvent could be attributed to two *** one hand,for the initial dissolution state,the distinguishing Hansen solubility parameter and polarity between methanol solvent and lignin oligomers resulted in the poor dispersion of the lignin *** the other hand,strong hydrogen bonds between methanol solvent and lignin oligomers during solvent shifting process,hindered the interactions among the lignin oligomers for self-assembly.

关键词： Lignin oligomers Alcohol solvent Self-assembly LNPs Solvent effects

Enhancing reversible hydrogen storage performance of 2LiBH_(4)–MgH_(2)via in-situ building heterogeneous nucleation sites

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Rare Metals 2024年第9期43卷 4367-4376页

作者： Wei Chen ya-Hui Sun Tian Xu Xue-bin Yu guang-Lin xia Department of Materials Science Fudan UniversityShanghai 200433China

2LiBH_(4)-MgH_(2)composite is one of the most attractive reactive hydride composites with a theoretic hydrogen capacity of 10.8 wt%.However,the large nucleation restriction of MgB_(2)during the second step of dehydrogenation results in sluggish hydrogen storage kinetics and high operating temperature,which hinders its practical application as on-board hydrogen storage ***,Al3Ti doped Al nanoparticles(AT NPs)are prepared by a facile chemical reduction reaction to improve the hydrogen storage performance of 2LiBH_(4)-MgH_(2)*** the initial H_(2)desorption process,MgAlB_(4)and TiB_(2)that have identical crystal structure and low d-value mismatch with MgB_(2)resulting from the reaction between AT NPs and 2LiBH_(4)-MgH_(2)composite serve as effective nucleation sites for the formation of MgB_(2).As a result,the apparent activation energy of the two-step H_(2)desorption of AT NPs doped 2LiBH_(4)-MgH_(2)composite are notably decreased to(110.0±5.9)and(119.6±1.4)kJ·mol^(-1),which is 55.5 and 33.5 kJ·mol^(-1)lower than that of the undoped *** importantly,a reversible hydrogen storage capacity of 9.2 wt%after 10cycles of H_(2)desorption and adsorption could be achieved,corresponding to a capacity retention rate of 99%.The building of reactive bimetallic catalyst towards in situ formation of heterogeneous nucleation sites provides a new strategy for improving the hydrogen storage performance of reactive hydride composites.

关键词： Reversible hydrogen storage Reactive hydride composites Catalytic effects Heterogeneous nucleation

A critical review on direct catalytic hydrogasification of coal into CH_(4):catalysis process configurations,evaluations,and prospects

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International Journal of Coal Science & Technology 2024年第3期11卷 51-85页

作者： Shuai yan Jun Feng Shenfu Yuan Zihong xia Fengshuang Han Xuan Qu Jicheng bi School of Materials and Chemical Engineering Ningbo University of TechnologyNingbo315211ZhejiangChina Zhejiang Institute of Tianjin University Ningbo315201ZhejiangChina State Key Laboratory of Coal Conversion Institute of Coal ChemistryChinese Academy of SciencesTaiyuan030001China School of Chemical Science and Engineering Key Laboratory of Medicinal Chemistry for Natural ResourceMinistry of EducationNational Center for Experimental Chemistry and Chemical Engineering Education DemonstrationYunnan Provincial Key Laboratory of Carbon Neutral and Green Low-Carbon TechnologyYunnan UniversityKunming650091China Department of Energy and Chemical Engineering East China University of Science and TechnologyShanghai200237China

Coal catalytic hydrogasification(CCHg)is a straightforward approach for producing CH_(4),which shows advantages over the mature coal-to-CH_(4) technologies from the perspectives of CH_(4) yield,thermal efficiency,and CO_(2) *** core of CCHg is to make carbon in coal convert into CH_(4) efficiently with a *** the past decades,intensive research has been devoted to catalytic hydrogasification of model carbon(pitch coke,activated carbon,coal char).However,the chemical process of CCHg is still not well understood because the coal structure is more complicated,and CCHg is a combination of coal catalytic hydropyrolysis and coal char catalytic *** review seeks to shed light on the catalytic process of raw coal during *** configuration of suitable catalysts,operating conditions,and feedstocks for tailoring CH_(4) formation were identified,and the underlying mechanisms were *** on these results,the CCHg process was evaluated,emphasizing pollutant emissions,energy efficiency,and reactor ***,the opportunities and strategic approaches for CCHg under the restraint of carbon neutrality were highlighted by considering the penetration of“green”H2,biomass,and CO_(2) into *** investigations from our laboratories demonstrated that the integrated CCHg and biomass/CO_(2) hydrogenation process could perform as an emerging pathway for boosting CH_(4) production by consuming fewer fossil fuels,fulfilling the context of green *** work not only provides systematic knowledge of CCHg but also helps to guide the efficient hydrogenation of other carbonaceous resources such as biomass,CO_(2),and coal-derived wastes.

关键词： Coal gasification Catalytic hydrogasification Methane Pressurized fluidized bed

Nicotinamide adenine dinucleotide phosphate oxidase in pancreatic diseases:Mechanisms and future perspectives

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World Journal of gastroenterology 2024年第5期30卷 429-439页

作者： ya-Wei bi Long-Song Li Nan Ru Bo Zhang xiao Lei Department of gastroenterology The First Medical Center of Chinese PLA General HospitalBeijing 100853China Department of Radiation Oncology Chinese PLA General HospitalBeijing 100853China

Pancreatitis and pancreatic cancer(PC)stand as the most worrisome ailments affecting the *** have dedicated efforts to unraveling the mechanisms underlying these diseases,yet their true nature continues to elude their *** this realm,oxidative stress is often believed to play a causal and contributory role in the development of pancreatitis and *** accumulation of reactive oxygen species(ROS)can cause oxidative stress,and the key enzyme responsible for inducing ROS production in cells is nicotinamide adenine dinucleotide phosphate hydrogen oxides(NOX).NOX contribute to pancreatic fibrosis and inflammation by generating ROS that injure acinar cells,activate pancreatic stellate cells,and mediate macrophage *** ROS production occurs during malignant transformation and pancreatic carcinogenesis,creating an oxidative microenvironment that can cause abnormal apoptosis,epithelial to mesenchymal transition and genomic ***,understanding the role of NOX in pancreatic diseases contributes to a more in-depth exploration of the exact pathogenesis of these *** this review,we aim to summarize the potential roles of NOX and its mechanism in pancreatic disorders,aiming to provide novel insights into understanding the mechanisms underlying these diseases.

关键词： Nicotinamide adenine dinucleotide phosphate hydrogen oxides Pancreatitis Pancreatic cancer Reactive oxygen species Mechanism

Pleomorphic rhabdomyosarcoma of the vagina: A case report

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World Journal of Clinical Cases 2024年第14期12卷 2396-2403页

作者： Pan Xu Shan-Shan Ling E Hu bi-xia Yi Department of gynecology The Affiliated Jinhua Hospital of Wenzhou Medical UniversityJinhua 321000Zhejiang ProvinceChina Zhejiang University School of Medicine Hangzhou 310006Zhejiang ProvinceChina

BACKgROUND Rhabdomyosarcoma(RMS)of the vagina in postmenopausal women is an extre-mely rare malignant tumor that was originally described as a unique group of soft tissue sarcomas originating from primitive mesenchymal *** was first re-ported in postmenopausal women in 1970,and fewer than 50 postmenopausal patients have been reported to *** SUMMARY A 68-year-old multiparous female was admitted to the hospital on October 11,2023,with the chief complaint of a mass causing vaginal prolapse with incomplete urination that had persisted for 4 *** vaginal mass was approximately the size of a pigeon egg;after lying down,the vaginal mass *** resection was performed,and vaginal pleomorphic RMS was diagnosed based on pathology and immunohistochemical staining *** patient is currently undergoing *** present study also reviewed the clinical,histolo-gical,and immunohistochemical features and latest treatment recommendations for vaginal *** abnormal vaginal mass should be promptly investigated through pelvic examination and appropriate *** current initial treat-ment for vaginal RMS is biopsy and primary *** When surgery is planned for vaginal RMS,an organ-preserving approach should be considered.

关键词： Rhabdomyosarcoma Vagina Postmenopausal woman Pleomorphic Case report

Low Concentration of Wenyang Tonglin Decoction Promotes Conjugation and Transfer of Drug-Resistant Plasmids among Heterologous Strains

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Chinese Journal of Integrative Medicine 2024年第8期30卷 721-728页

作者： WANg bi-yan BU Hong-shi xia Li-bo JIANg xiang-yu TONg yan-qing Department of Traditional Chinese Medicine Changchun University of Traditional Chinese MedicineChangchun130000China

Objective To investigate the effect of low concentration of Wenyang Tonglin Decoction(WTD)on the binding conditions of R45 plasmid conjugative transfer under liquid phase conjugation and its *** Escherichia coli CP9(R45)and Staphylococcus aureus RN450RF were cultured in medium containing WTD,and their minimum inhibitory concentration(MIC)values were *** promoter fusion technology,*** CP9(R45)containing a promoter fusion was obtained.β-galactosidase activity of TrfAp and TrbBp was tested,and the mRNA expression of regulatory factors(TrbA,KorA,and KorB)was detected by real-time fluorescent quantitative polymerase chain *** The MIC of *** CP9(R45)was 400 g/L and that of *** RN450RF was 200 g/*** the drug concentration in the culture medium was 200 g/L,the highest number of conjugants was(3.47±0.20)×10^(7) CFU/mL At 90 h of conjugation,the maximum number of conjugants was(1.15±0.06)×10^(8) CFU/mL When the initial bacterial concentration was 10^(8) CFU/mL,the maximum number of conjugants was(3.47±0.20)×10^(7) CFU/*** the drug concentration was 200 g/L,theβ-galactosidase activity of TrfAp and TrbBp significantly increased;the relative quantification of TrbA,KorA and KorB were significantly *** Low concentration of WTD promoted the development of bacterial resistance by affecting promoters and inhibiting the expression of regulatory factors.

关键词： urinary tract infection Chinese medicine drug-resistant plasmid heterozygous strains conjugation transfer

Association between heat and upper urinary tract stones morbidity and medical costs: A study in the subtropical humid climate zone

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Advances in Climate Change Research 2024年第4期15卷 717-724页

作者： Chen-Lu yaNg Jun-Zhe BAO Peng bi ya-Dong ZHANg Chao-Ming TAN Kai CHEN College of Public Health Zhengzhou UniversityZhengzhou 450001China School of Public Health The University of AdelaideAdelaide 5000Australia Department of Andrology The First Affliated Hospital of Sun Yat-sen UniversityGuangzhou 510080China Nanjing Social Insurance Management Center Nanjing 210008China Department of Environmental Health Sciences Yale UniversityNew Haven 06520USA yale Center on Climate Change and Health Yale UniversityNew Haven 06520USA

Urolithiasis is a heat-specific *** heat-related urolithiasis susceptibility subtypes,economic burden,and modifying factors could assist governments in targeting interventions to reduce the heat-related health risks of urolithiasis *** collected data on 23,492 patients with upper urinary tract stones(main subtypes of urolithiasis)from 2013 to 2017 in Nanjing,*** adopted generalized additive quasi-Poisson models to examine the associations between daily mean temperatures and morbidity of upper urinary tract stones,while generalized additive gaussian models were used to explore the relationships between temperatures and log-transformed medical *** examined the modification effects of disease subtypes(kidney and ureteral calculus),sex,and age through stratified analyses and the modif-cation effects of other meteorological factors by introducing interaction terms in the *** found that short-term summer heat exposure has a statistically significant effect on ureteral calculus morbidity but not on kidney calculus *** ureter calculus,a 1℃ temperature increase was associated with a 4.36%(95%confidence interval[CI]:1.94%,6.83%)increase in daily hospitalization and a 5.44%(95%CI:2.71%,8.25%)increase in daily medical *** attributable fraction associated with heat(greater than the median value of daily mean temperature,26.8℃)was 7.85%(95%empirical confidence interval[eCI]:3.64%,11.44%)for hospitalization and 9.36%(95%eCI:4.91%,13.14%)for medical *** effects of heat on ureter calculus morbidity were significantly higher among the males and those with high sunshine duration than females and those with low sunshine ***-term summer heat exposure was associated with increased morbidity and medical costs of ureteral *** government organizations should take effective intervention measures,including community health education,to reduce the health hazards and economic losses caused by heat.

关键词： Heat Upper urinary tract stones Economic burden Modification effects

Unlocking the potential:How acupuncture reshapes the liver-centered lipid metabolism pattern to fight obesity

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Journal of Integrative Medicine 2024年第5期22卷 523-532页

作者： Shu-rui yang Li Chen Dan Luo ya-yuan Wang Feng-xia Liang College of Acupuncture and Orthopedics Hubei University of Chinese MedicineWuhan 430061Hubei ProvinceChina Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion Wuhan 430061Hubei ProvinceChina Hubei Shizhen Laboratory Wuhan 430060Hubei ProvinceChina Hubei International Science and Technology Cooperation Base of Preventive Treatment by Acupuncture and Moxibustion Wuhan 430061Hubei ProvinceChina Acupuncture and Moxibustion Department Affiliated Hospital of Hubei University of Chinese Medicine(Hubei Provincial Hospital of Traditional Chinese Medicine)Wuhan 430060Hubei ProvinceChina

Obesity,a widespread global health issue,is frequently linked to disrupted lipid metabolism,resulting in excessive accumulation of adipose tissue and associated health ***,a traditional Chinese medical modality,has exhibited potential as a viable intervention for addressing *** underlying mechanism proposed involves the stimulation of specific acupoints to exert a regulatory influence on hepatic *** liver has a central role in lipid metabolism,including processes such as lipid synthesis,storage and *** is believed to enhance the liver’s efficiency in processing lipids,thereby reducing lipid accumulation and improving metabolic *** indicates that acupuncture can influence the expression of certain genes and proteins involved in lipid metabolism in the *** includes upregulating genes that promote lipid breakdown and oxidation,and downregulating those involved in lipid ***,acupuncture has been shown to improve insulin sensitivity,which is crucial for the regulation of lipid ***,the potential anti-inflammatory effects of acupuncture may play a significant role in its efficacy for the treatment of *** presence of chronic inflammation has been strongly associated with metabolic disorders such as *** its ability to mitigate inflammation,acupuncture can potentially aid in the restoration of lipid metabolism and the reduction of body ***,the amelioration of hepatic oxidative stress represents another mechanism by which acupuncture may contribute to the reduction of lipid ***,the liver,being the primary site of lipid metabolism,maintains communication with various organs including the brain,adipose tissue,skeletal muscle and *** perspective opens new avenues for the treatment of obesity,emphasizing the importance of holistic approaches in managing complex metabolic disorders.

关键词： Acupuncture Obesity Liver-centered lipid metabolism pattern