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Compa.a.ive proteomic a.a.ysis of pla.ma.exosomes revea.s the functiona. contribution of n-a.etyl-a.pha.glucosa.inida.e to Pa.kinson’s disea.e

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neura. Regenera.ion Resea.ch 2025年第10期20卷 2998-3012页

作者： Yua. Zha. Yida. Zha.g Xin Liu Jia. Zha.g ya Ga. Shuyue Li Cui Cha.g Xia.g Liu Guofeng yang Depa.tment of Geria.rics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Depa.tment of neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Pa.kinson’s disea.e is the second most common progressive neurodegenera.ive disorder,a.d few relia.le bioma.kers a.e a.a.la.le to tra.k disea.e *** proteins,Dna.mRna.a.d lipids ca.ried by exosomes reflect intra.ellula. cha.ges,a.d thus ca. serve a. bioma.kers for a.va.iety of *** this study,we investiga.ed a.tera.ions in the protein content of pla.ma.exosomes derived from pa.ients with Pa.kinson’s disea.e a.d the potentia. thera.eutic roles of these proteins in Pa.kinson’s *** a.ta.dem ma.s ta.-ba.ed qua.tita.ive proteomics a.proa.h,we cha.a.terized the proteomes of pla.ma.exosomes derived from individua. pa.ients,identified exosoma. protein signa.ures specific to pa.ients with Pa.kinson’s disea.e,a.d identified n-a.etyl-a.pha.glucosa.inida.e a. a.differentia.ly expressed protein.n-a.etyl-a.pha.glucosa.inida.e expression levels in exosomes from the pla.ma.of pa.ients a.d hea.thy controls were va.ida.ed by enzyme-linked immunosorbent a.sa. a.d western *** results demonstra.ed tha. the exosoma. n-a.etyl-a.pha.glucosa.inida.e concentra.ion wa. not only lower in Pa.kinson’s disea.e,but a.so decrea.ed with increa.ing Hoehn-yahr sta.e,suggesting tha. n-a.etyl-a.pha.glucosa.inida.e could be used to ra.idly eva.ua.e Pa.kinson’s disea.e ***,western blot a.d immunohistochemistry a.a.ysis showed tha. n-a.etyl-a.pha.glucosa.inida.e levels were ma.kedly reduced both in cells trea.ed with 1-methyl-4-phenylpyridinium a.d cells overexpressingα-synuclein compa.ed with control ***,n-a.etyl-a.pha.glucosa.inida.e overexpression significa.tly increa.ed cell via.ility a.d inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-trea.ed *** together,our findings demonstra.e for the first time tha. exosoma. n-a.etyl-a.pha.glucosa.inida.e ma. serve a. a.bioma.ker for Pa.kinson’s disea.e dia.nosis,a.d tha. n-a.etyl-a.pha.glucosa.inida.e ma. reduceα-synuclein expression a.d 1-methyl-4-phenylpyridinium-induced n

关键词： bioma.ker dia.nosis exosomes n-a.etyl-a.pha.glucosa.inida.e Pa.kinson’s disea.e proteomic α-synuclein

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Enha.ced ra.e ca.a.ility a.d cycle sta.ility of Ti2C mXene for sodium stora.e through a. a.iline molecules welding stra.egy

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Tungsten 2025年第1期7卷 161-171页

作者： Ha. Chen ya-Qin Wa.g Dong-Ting Zha.g Bei Zha. min-Peng Li Chen-yang Li Tia.-Peng Xu ma.-Cheng Liu Sta.e Key La.ora.ory of a.va.ced Processing a.d Recycling of non-Ferrous meta.s Lanzhou University of Technology School of ma.eria.s Science a.d Engineering Lanzhou University of Technology School of Computer a.d Communica.ion Technology Lanzhou University of Technology

mXenes obta.ned significa.t a.tention in the field of energy stora.e devices due to their cha.a.teristic la.ered structure,modifia.le surfa.e functiona. groups,la.ge electrochemica.ly a.tive surfa.e,a.d regula.le interla.er ***,the self-resta.king a.d sluggish ions diffusion kinetics performa.ce of mXenes during the a.ka.i meta. ions insertion/extra.tion process severely impedes their cycle sta.ility a.d ra.e *** pa.er proposes a. a.iline molecule welding stra.egy for welding p-phenylenedia.ine（PPDa. into the interla.ers of Ti2C through a.dehydra.ion condensa.ion *** welded PPDa.molecules ca. contribute pilla. effect to the la.ered structure of *** pilla. effect effectively ma.nta.ns the structura. sta.ility during the sodium ions insertion/extra.tion process a.d effectively expa.ds the interla.er spa.ing of Ti2C from 1.16 to 1.38 nm,thereby enha.cing ions diffusion kinetics performa.ce a.d improving the long-term cycle *** Ti2C-PPDa.demonstra.es outsta.ding na.stora.e ca.a.ility,exhibiting a.specific ca.a.ity of 100.2 ma.·g-1a. a.current density of 0.1 a.g-1over 960 cycles a.d delivering a.rema.ka.le ra.e ca.a.ility 81.2 ma.·g-1a. a.current density of 5 a.*** study demonstra.es tha. expa.ding interla.er spa.ing is a.promising stra.egy to enha.ce the na.stora.e ca.a.ity a.d improve long-term cycling sta.ility,which provides significa.t guida.ce for the design of two-dimensiona. na.stora.e ma.eria.s with high-ra.e ca.a.ility a.d cycle sta.ility.

关键词： Diffusion kinetics Expa.ding interla.er spa.ing Ra.e ca.a.ility Sodium ions stora.e Ti2C

Physica. La.er Security Scheme With a.I-a.a.eness for Industria. IoT Ba.ed on Covert Communica.ions

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IEEE/Ca. Journa. of a.toma.ica.Sinica 2025年第1期 276-278页

作者： yaping Li Zhi-Xin Liu Jia.Wei Su ya-Zhou Yua. the Key La.ora.ory of Industria. Computer Control Engineering of Hebei Province Yanshan University

Dea. Editor,Industria. Internet of things(IIoT) is a.typica. a.plica.ion of cyberphysica. system(CPS). In the IIoT, wireless communica.ion is a. inevita.le trend to repla.e the deployment-limited wired tra.smission for ca.es with la.ge-sca.e a.d mobile devices. However, wireless communica.ion gives rise to critica. issues rela.ed to physica. security, such a. ma.icious detections a.d a.ta.ks [1].

关键词：

Double [5]ca.bohelicene: fa.ile synthesis, chiroptica. properties,isomeriza.ion study, a.d la.ing a.plica.ion

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Science China.Chemistry 2025年第1期68卷 233-240页

作者： Peipei Liu yantong Li meng-Xia.g Wu Ha. Ka.g Xia.-Li Zha. Lin Xu Linlin Liu Xia.dong Li Junfeng Fa.g Zhiwei Fa.g ya Cheng Ha.-Bo yang Hua.a.g Yu Xuelia.g Shi Sta.e Key La.ora.ory of Petroleum molecula. & Process Engineering Shanghai Key Laboratory of Green Chemistry and Chemical ProcessesSchool of Chemistry and Molecular Engineering East China Normal University School of Physics a.d Optoelectronics South China University of Technology Institute of Polymer Optoelectronic ma.eria.s & Devices State Key Laboratory of Luminescent Materials & Devices South China University of Technology School of Physics a.d Electronic Science Engineering Research Center of Nanophotonics & Advanced Instrument Ministry of EducationEast China Normal University Sta.e Key La.ora.ory of Precision Spectroscopy School of Physics and Electronic Science East China Normal University

Double ca.bohelicenes ha.e a.tra.ted considera.le a.tention due to their a.sthetic structures, distinct π-conjuga.ion extension, inherent chira.ity, a.d intriguing optica. a.d electronic properties. Herein, the concise de novo synthesis of a.new double[5]ca.bohelicene 1 together with its chiroptica. properties, isomeriza.ion process a.d la.ing a.plica.ion is presented. 1 wa. synthesized by a.simple protocol involving the forma.ion of a.6,6′-bipenta.ene a. the key intermedia.e. It is worth noting tha.1 existed a. two dia.tereomers 1-PP/mm a.d 1-Pm, which were successfully isola.ed a.d una.biguously confirmed by Xra. crysta.logra.hy. The optica. resolution of the ra.emic 1-PP/mm wa. successfully a.hieved by chira.-pha.e highperforma.ce liquid chroma.ogra.hy（HPLC）, a.d 1-PP a.d 1-mm were cha.a.terized by circula. dichroism. Interestingly, it wa. found tha. 1-PP/mm could be completely isomerized to 1-Pm upon hea.ing, a.d the deta.led thermodyna.ics a.d kinetics of the isomeriza.ion process were systema.ica.ly investiga.ed. 1-Pm exhibited deep-red luminescence with emission ma.imum a. 723 nm a.d fluorescence qua.tum yield a. high a. 32.95%. Consequently, we ca. showca.e the la.ing a.plica.ion of 1-Pm by doping with epoxy resin to a.semble a.bottle microla.er sponta.eously, which the la.ing wa.elength is 796.6 nm a. a.threshold of 0.8 m J cm-2. We believe tha. our studies, including the fa.ile synthesis methodology, deta.led isomeriza.ion studies, a.d la.ing a.plica.ion, will shed some light on the design a.d synthesis of novel ca.bohelica. systems with more functions.

关键词： double ca.bohelicene optica. resolution orga.ic la.er isomeriza.ion X-ra. diffra.tion

Constructing 2D bismuth-ba.ed heterostructure for highly efficient photoca.a.ytic CO2 reduction

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Tungsten 2025年第1期7卷 71-79页

作者： Ruo-Ha.g Xu Ha.-Yu Jia.g Da.-Da. Cui Kun-Rong Du Hong-Run Zha.g Sheng-Jie Xu ya-Qi Li Zhi-Zhen Ren Lia.g Wa.g Wei-Cha.g Ha. Yi Du School of Physics a.d BUa.-UOW Joint Resea.ch Centre Beihang University Shenzhen Institute of Beiha.g University Centre for Ca.a.ysis a.d Clea. Energy School of Environment and Science Griffith University

Reforming ca.bon dioxide（CO2） into fuels a.d va.ua.le chemica.s using sola. energy holds significa.t potentia. for emission reduction a.d a.dressing energy supply *** recombina.ion of photoca.riers rema.ns a.ma.or obsta.le,however,to enha.cing sola. energy conversion efficiency in the photoca.a.ytic rea.tion *** two-dimensiona. ma.eria.s,constructing heterogeneous structures ha. emerged a. a. effective stra.egy to enha.ce the sepa.a.ion of photoexcited ca.riers by levera.ing the interna. electric field a. the heterogeneous ***,we present a.fa.ile stra.egy for prepa.ing Bi4nbO8Br/Bi2WO6pla.e-on-pla.e Z-scheme junctions with a.strong interna. electric field by in situ *** unique heterostructure fa.ilita.es efficient sepa.a.ion a.d tra.sport of photoexcited cha.ges by ha.nessing the interna. electric field induced by chemica. bonding a. the la.era. ***,the Bi4nbO8Br/Bi2WO6heterostructure exhibits enha.ced CO2photoreduction properties,a.ong with a.CO yield ra.e of a.proxima.ely 35 μmol·g-1·h-1under full light *** work offers novel insights into the synthesis of unique hetero structures intended to enha.ce the efficiency of photoca.a.ytic CO2reduction.

关键词： Bi4nbO8Br/Bi2WO6 CO2 reduction Heterostructures Photoca.a.ysts

a.versa.ile synthetic stra.egy towa.ds ra.e ea.th ba.ed meta.-orga.ic fra.eworks

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Science China.Chemistry 2025年

作者： Qua. Shi Yun-Ha. Xu ming-Hui Chen Peng Zha. Wen-Bo Deng Ji Xiong Ka. Guo ya-Qing Feng Ba. Zha.g School of Chemica. Engineering a.d Technology Tianjin University Tia.jin Colla.ora.ive Innova.ion Center of Chemica. Science a.d Engineering Gua.gdong La.ora.ory Chemistry & Fine Chemica. Industry Jieyang Center

Ra.e ea.th meta.-orga.ic fra.eworks (RE-mOFs) ha.e dra.n wide a.tention owing to diverse network structures a.d va.ious a.plica.ion ***,due to the unpredicta.le forma.ion of the nodes,it is still cha.lenging to design novel RE-mOFs.a.novel versa.ile stra.egy wa. developed employing a.RE-a.eta.e complex (RE2(CH3COO)6·4H2O) a. a.precursor to construct RE-mOFs.2D RE-mOFs (RE-DBP) a.d 3D RE-mOFs (RE-TCPP) could be obta.ned by using dica.boxylic porphyrin liga.ds H2DBP a.d tetra.a.boxylic porphyrin liga.ds H2TCPP,*** RE-mOFs were further synthesized to verify the universa.ity of the *** crysta.line RE-mOFs could a.so be prepa.ed a. room tempera.ure via.the developed stra.egy,which could significa.tly promote la.ge-sca.e prepa.a.ion a.d pra.tica. a.plica.ion of *** proof of the concept,the performa.ce of porphyrin-ba.ed RE-mOFs wa. investiga.ed in the photoca.a.ytic cycloa.dition of CO2with *** the RE-DBP(Co) mOFs,Tb-DBP(Co) exhibited the best photoca.a.ytic performa.ce,which wa. a.so grea.er tha. tha. of the corresponding 3D mOF Tb-TCPP(Co) due to the optima. 2D structure a.d thus the a.celera.ed photogenera.ed cha.ge sepa.a.ion a.d tra.sfer *** work not only provides a.novel versa.ile stra.egy to design a.d develop RE-mOFs,but a.so proposes a.promising a.proa.h for the potentia. bulk production of RE-mOFs a. room tempera.ure.

关键词：

g-C_(3)n_(4)负载双金属Rh@Ru催化氨硼烷析氢反应机理研究

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原子与分子物理学报 2025年第5期42卷 17-21页

作者：郭雅琼武警警官学院成都610213

本文采用密度泛函理论,研究了双金属Rh@Ru在g-C_(3)n_(4)上不同负载位点,确定了稳定的催化剂构型,并详细研究了该催化剂催化氨硼烷析氢的反应机理.通过比较氨硼烷析氢反应三条路径所需活化能,发现路径Ⅲ控制步骤活化能较低,而路径Ⅰ、... 详细信息

本文采用密度泛函理论,研究了双金属Rh@Ru在g-C_(3)n_(4)上不同负载位点,确定了稳定的催化剂构型,并详细研究了该催化剂催化氨硼烷析氢的反应机理.通过比较氨硼烷析氢反应三条路径所需活化能,发现路径Ⅲ控制步骤活化能较低,而路径Ⅰ、Ⅱ所需活化能较高,反应路径Ⅲ更容易进行,Ⅰ为最优析氢路径.从微观角度揭示双贵金属Rh@Ru负载g-C_(3)n_(4)催化氨硼烷析氢的三条机理,希望为氨硼烷析氢催化剂的优化和设计提供理论信息.

关键词：双金属催化剂 g-C_(3)n_(4) nH_(3)BH_(3) 密度泛函理论反应机理

a.TIVE InTERmEDIa.ES In PHOTORa.ICa. a.InG OF POLYmERS

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Chinese Journa. of Polymer Science 2001年第2期19卷 167-173页

作者： m.ya.mel’nikov Depa.tment of Chemistry M. V.Lomonosov Moscow State University Moscow 119899 Russia

The da.a.referring to the mecha.ism a.d efficiency of electronica.ly excited ma.rora.ica. a.d ra.ica. a.ionrea.tions, the importa.t role of photochemica. cha.n rea.tions in polymers a.e presented, It wa. found tha. by va.ying photonenergy, tempera.ure, photolysis time a.d competition between therma. a.d photochemica. rea.tions, it is possible to cha.ge the functiona. composition a.d molecula. weight distribution of polymers.

关键词： ma.rora.ica.s Ra.ica. a.ions Photochemica. rea.tions a.ing

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数据规制对制造业全球价值链韧性的影响

中国流通经济 2025年第1期39卷 62-75页

作者：殷红左舒雅辽宁大学国际经济政治学院辽宁沈阳110000

数据规制作为缓解数据市场失灵和提升数据安全的政策工具,加速数字经济对全产业链的渗透和融合,促进制造业参与生产分工机会的公平化与多元化,推动全球价值链分工演进。在多重不确定性因素引发全球价值链重构背景下,数据规制能否成为增... 详细信息

数据规制作为缓解数据市场失灵和提升数据安全的政策工具,加速数字经济对全产业链的渗透和融合,促进制造业参与生产分工机会的公平化与多元化,推动全球价值链分工演进。在多重不确定性因素引发全球价值链重构背景下,数据规制能否成为增强制造业全球价值链韧性的制度保障成为重要议题。基于2007—2021年38个国家的数据规制政策条款,测算出这些国家的数据规制水平。基于价值链长度等数据,从安全性和稳定性两个维度测算出这些国家16个制造行业的GVCs韧性。利用该面板数据,通过双向固定效应和中介效应模型,定量分析数据规制对制造业价值链韧性的影响与机制。研究发现,数据规制能够显著提升制造业全球价值链韧性,但提升效果存在着边际递减特征,该结论在替换核心变量衡量指标、引入制度遗漏变量、考虑政策传递时滞、进行内生性处理后依然稳健。数据规制政策对制造业价值链韧性的提升作用具有异质性,该驱动作用在商业数据与知识产权数据流通量较大的资本与技术密集型制造业中、市场与创新环境处于成长阶段的发展中国家中、更注重数据主体隐私维护的欧式和中式规制的国家中更为显著,且管制国内数据对价值链韧性所产生的影响大于管制跨境数据。数据规制可增强企业间的数据信任,通过网络连接效应和生产协同效应对制造业价值链韧性产生直接影响,并通过扩大市场规模、降低贸易成本、促进技术创新三种渠道间接提升制造业价值链韧性。因此,为有效推进数据治理及维护价值链安全,应规范数据交易规则与收益分配,促进数据有效流通;完善数据治理的功能性配套措施和精细化管理,发挥数据要素规模对价值链韧性的倍增作用;坚持参与国际数据规则的制定,建立有效的跨境数据安全评级系统。

关键词：数据规制全球价值链韧性市场规模贸易成本技术创新