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Biomedical and Environmental Sciences 2021年第7期34卷 540-551页

作者： JIA Rong CHEN ya Xiong DU ya Rong HU Bu Rong Key Laboratory of Space radiobiology of Gansu Province&CAS Key Laboratory of Heavy Ion radiation Biology and Medicine Institute of Modern PhysicsChinese Academy of SciencesLanzhou 730000GansuChina School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100039China Department of radiation Medicine School of Public Health and ManagementWenzhou Medical UniversityWenzhou 325035ZhejiangChina

Objective To obtain precise data on the changes in the levels of 29 cytokines in mice after high or low linear energy transfer(LET)irradiation and to develop an accurate model of radiation exposure based on the cytokine levels after *** Plasma samples harvested from mice at different time points after carbon-ion or X-ray irradiation were analyzed using meso-scale discovery(MSD),a high-throughput and sensitive electrochemiluminescence measurement *** estimation equations were set up using multiple linear regression *** The relative levels of IL-6 at 1 h,IL-5 and IL-6 at 24 h,and IL-5,IL-6 and IL-15 at 7 d after irradiation with two intensities increased *** minimum measured levels of IL-5,IL-6 and IL-15 were up to 4.0076 pg/mL,16.4538 pg/mL and 0.4150 pg/mL,*** addition,dose estimation models were established and *** The MSD assay can provide more accurate data regarding the changes in the levels of the cytokines IL-5,IL-6 and *** cytokines could meet the essential criteria for radiosensitive biomarkers and can be used as radiation *** prediction models can conveniently and accurately estimate the exposure dose in irradiated organism.

关键词： MSD assay Low or high LET irradiation Mouse plasma Cytokines Dose estimation model

Seasonal freezing-thawing process and hydrothermal characteristics of soil on the Loess Plateau, China

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Journal of Mountain Science 2021年第11期18卷 3082-3098页

作者： CHOU ya-ling WANG Li-jie Key Laboratory of Disaster Prevention and Mitigation in Civil Engineering of Lanzhou University of Technology Lanzhou 730050China

In seasonally frozen soil regions,freezing-thawing action and hydrothermal effect have strong influence on physical and mechanical behavior of shallow soil.A field experiment on the Loess Plateau in Northwest China was carried out to analyze the freezing-thawing process and hydrothermal characteristics of shallow soil considering the climate *** results show that the maximum seasonal freezing depth under bare ground surface in this area is from 20 cm to 50 *** ground temperature shows a similar changing trend with air temperature,but it has lagged behind the air temperature,and the ground temperature amplitude exponentially decreases with the increase of soil *** seasonally frozen soil has experienced four typical stages:unfrozen period,alternate freezing period,freezing period and alternate thawing *** freezing-thawing process is characterized by unidirectional freezing and bidirectional *** water content of shallow soil is significantly affected by air temperature,evaporation and precipitation,and the soil water content shows a"low-high-low"changing trend with the increase of *** soil temperature and water content interact with each other,and are often *** variation trend of soil moisture with time is consistent with the change trend of the ground temperature with time in each soil layer,andthe degree of consistency is higher in the near surface soil than that in the lower ***,the spatial-temporal characteristics of soil moisture and temperature is that the volumetric water content and ground temperatureof near surface soil have strong variability,and the range valueKa and coefficient of variation Cvof soil water content and ground temperaturein different seasons show a decreasing trend with the increase of depth.

关键词： Seasonally frozen soil Freezing-thawing process Hydrothermal characteristics Loess Plateau

Assessing the Fishery Resource Status of China’s Coastal Waters Using Surplus Production Models

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Journal of Ocean University of China 2021年第5期20卷 1236-1244页

作者： ZHANG Qingqing LIU Qun HAN ya’nan College of Fisheries Ocean University of ChinaQingdao 266003China

Surplus production models(SPMs)are among the simplest and most widely used fishery stock assessment *** catch-effort data analysis(CEDA)and a surplus production model incorporating covariates(ASPIC)are softwares for analyzing fishery catch and fishing effort data using nonequilibrium *** China Fishery Statistical Yearbook,annual fishery production and fishing effort data of the Yellow Sea,Bohai Sea,East China Sea,and South China Sea have been published from 1979 till *** its catch and fishing effort data from 1980 to 2018,we apply the CEDA and ASPIC to evaluate fishery resources in Chinese coastal *** results show that the total maximum sustainable yield(MSY)estimate of the four China seas is 10.05-10.83 million tons,approximately equal to the marine fishery catch(10.44 million tons)reported in *** can be concluded that China’s coastal fishery resources are currently fully exploited and must be protected with a precautionary *** softwares produced similar results;however,the CEDA had a much higher R2 value(above 0.9)than ASPIC(about 0.2),indicating that CEDA can better fit the data and therefore is more suitable for analyzing the fishery resources in the coastal waters of China.

关键词： Chinese coastal waters fishery resources surplus production models(SPMs) catch-effort data analysis(CEDA) a surplus production model incorporating covariates(ASPIC) China Fishery Statistical Yearbook

Numerical solutions of 2-D steady compressible natural convection using high-order flux reconstruction

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Acta Mechanica Sinica 2019年第2期35卷 401-410页

作者： yaojie Yu Feng Liu Tingbo Zhou Chao Gao ya Liu National Key Laboratory of Aerodynamic Design and Research Northwestern Polytechnical UniversityXi’an 710072 China Department of Mechanical and Aerospace Engineering University of California Irvine Irvine CA 92697 USA Facility Design and Instrumentation Institute China Aerodynamics Research and Development CenterMianyang 621000 China

Low Mach number flows are common and typical in industrial applications. When simulating these flows, performance of traditional compressible flow solvers can deteriorate in terms of both efficiency and accuracy. In this paper, a new high-order numerical method for two-dimensional(2-D)state low Mach number flows is proposed by combining flux reconstruction(FR)and preconditioning. Firstly, a Couette flow problem is used to assess the efficiency and accuracy of preconditioned FR. It is found that the FR scheme with preconditioning is much more efficient than the original FR scheme. Meanwhile,this improvement still preserves the numerical accuracy. Using this new method and without the Boussinesq assumption,classic natural convection is directly simulated for cases of small and large temperature differences. For the small temperature difference, a p and h refinement study is conducted to verify the grid convergence and accuracy. Then, the influence of the rayleigh number (ra) is analyzed. By comparing with the reference results, the numerical results of preconditioned FR is very close to that calculated by incompressible solvers. Furthermore, a large temperature difference test case is calculated and analyzed, indicating this method is not limited by the Boussinesq assumption and is also applicable to heat convection with large temperature differences.

关键词： Flux reconstruction Preconditioning method Low Mach flows Natural convection

Mechanical Properties and Retained Austenite Transformation Mechanism of TRIP-Aided Polygonal Ferrite Matrix Seamless Steel Tube

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Journal of Iron and Steel Research International 2011年第8期18卷 73-78页

作者： ZHANG Ming-ya ZHU Fu-xian ZHENG Dong-sheng State Key Laboratory of Rolling and Automation Northeastern University Shenyang 110819 Liaoning China

Through the comparison of microstructure for polygonal ferrite （PF） matrix transformation induced plasticity （TRIP） seamless steel tube at different positions before and after tensile rupture, the transformation behavior of retained austenite （ra） was studied. The results showed that there were no yield points in tensile process and the splendid elongation and tensile strength were contributed by the uniform ferrite/bainite grains and the transformation of ra. The stability of ra was to some extent in inverse proportion with the ability of transformation induced plas ticity. The coarse retained austenite located in ferrite and ferrite/bainite laths were all transformed into martensite during the tensile process.

关键词： TRIP steel retained austenite austempering heat treatment

Complex spherical-wave elastic inversion using amplitude and phase reflection information

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Petroleum Science 2022年第3期19卷 1065-1084页

作者： Guang-Sen Cheng Xing-yao Yin Zhao-Yun Zong ya-Ming yang School of Geosciences China University of Petroleum(East China)QingdaoShandong 266580China Pilot National Laboratory for Marine Science and Technology(Qingdao) QingdaoShandong 266580China Shandong Provincial Key Laboratory of Deep Oil and Gas QingdaoShandong 266580China

Unlike the real-valued plane wave reflection coefficient(PRC)at the pre-critical incident angles,the frequency-and depth-dependent spherical-wave reflection coefficient(SRC)is more accurate and always a complex value,which contains more reflection amplitude and phase *** near field,the imaginary part of complex SRC(phase)cannot be ignored,but it is rarely considered in seismic *** promote the practical application of spherical-wave seismic inversion,a novel spherical-wave inversion strategy is *** complex-valued spherical-wave synthetic seismograms can be obtained by using a simple harmonic superposition *** is assumed that geophone can only record the real part of complex-valued *** imaginary part can be further obtained by the Hilbert transform *** also propose the concept of complex spherical-wave elastic impedance(EI)and the complex spherical-wave EI ***,a novel complex spherical-wave EI inversion approach is proposed,which can fully use the reflection information of amplitude,phase,and *** the inverted complex spherical-wave EI,the velocities and density can be further *** data and field data examples show that the elastic parameters can be reasonably estimated,which illustrate the potential of our spherical-wave inversion approach in practical applications.

关键词： Complex seismic traces Spherical-wave theory Reflection amplitude and phase Elastic impedance Bayesian inversion

Correlation between single nucleotide polymorphism of rs3811047 in IL-1 F7 gene and rheumatoid arthritis susceptibility among Han population in central plains of China

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Asian Pacific Journal of Tropical Medicine 2013年第1期6卷 73-75页

作者： Li-Pu Shi ya He Zhi-Dui Liu Department of Rheumatology People's Hospital of Zhengzhou

Objective:To discuss the association between single nucleotide polymorphism(SNP) of rs3811047 in IL-1 F7 gene and rheumatoid arthritis(ra) susceptibility among the Han population in central plains of ***:A total of 276 ra patients admitted to our hospital from December 2009 to December 2011 together with 276 healthy physical examinees in the same period were chosen as the *** typing for rs3811047 SNP in IL-1 F7 gene was carried out by using ligase detection reaction and polymerase chain reaction *** the frequency of each allele and genotypes distribution was calculated so as to evaluate the association between genotype distribution and ra ***:The frequency of A allele of rs3811047 in IL-1 F7 gene in ra group and control group was 16.27%and 17.68%,respectively,and that of G allele in two groups was 83.73%and 82.32%,*** difference between two groups wasn’t statistical significant(P >0.05).The frequency of genotype AA,AG and GG in ra group was 2.19%,27.84%and 69.97%,respectively,while that in control group was 2.94%,29.78%and 67.28%, *** difference of distribution of three genotypes was not statistically significant (P >0.05).ra patients with A allele were better than those without A allele in joint swelling index, rest pain,HAQ scoring and blood *** was significant difference between two groups in above indexes(Pra susceptibility among the Han population in central plains of China and rs3811047 SNP iniL-1 F7 gene is ***,A allele of rs3811047 has certain influence on the condition of ra patients.

关键词： Rheumatoid arthritis IL-1 F7 gene Single nucleotide polymorphism Susceptibility

Effect of family caregiver nursing education on patients with rheumatoid arthritis and its impact factors:A randomized controlled trial

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World Journal of Clinical Cases 2021年第28期9卷 8413-8424页

作者： Jing Li Ying Zhang ya-Juan Kang Nan Ma Department of Immunology and Rheumatology The Third Hospital of Hebei Medical UniversityShijiazhuang 050051Hebei ProvinceChina

BACKGROUND Rheumatoid arthritis(ra)is a common autoimmune *** education for family caregivers is considered a workable and effective intervention,but the validity of this intervention in ra has not been *** To explore whether family caregiver nursing education(FCNE)works on patients with ra and the factors that influence *** In this randomized controlled study,a sample of 158 pairs was included in the study with 80 in the intervention group and 78 in the control *** data of patients and caregivers was *** FCNE intervention was admi-nistered to caregivers,and inflammation level indicators,disease activity indicators and mood disorder indicators of patients were followed up and *** Baseline characteristics of the intervention and the control groups had no significant *** were significantly reduced in the intervention group compared to the control *** intervention group showed significant differences in stratification of relationship,education duration and *** The effect of FCNE on ra is multifaceted,weakening inflammation level,alleviating disease activity and relieving mood *** between caregiver and patient,caregiver’s education level and patient’s age may act as impact factors of FCNE.

关键词： Nursing education Family nursing Rheumatoid arthritis Family caregivers Depression Anxiety

Hepatitis B virus reactivation in rheumatoid arthritis

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World Journal of Clinical Cases 2022年第1期10卷 12-22页

作者： ya-Li Wu Jing Ke Bao-Yu Zhang Dong Zhao Center for Endocrine Metabolism and Immune Diseases Beijing Luhe HospitalCapital Medical UniversityBeijing 101149China

Rheumatoid arthritis(ra)is an autoimmune disease characterized by proliferative synovitis,which can cause cartilage and bone damage as well as functional ***-modifying anti-rheumatic drugs have significantly improved the prognosis of ra ***,people with ra,when combined with hepatitis B virus(HBV)infection,may experience reactivation of HBV during treatment with anti-rheumatic *** outcome of HBV reactivation(HBVr)varies from liver inflammation to liver failure,while insufficient HBV screening in ra patients has been reported in various ***,it is necessary to identify patients at high risk before starting immunosuppressive *** immune response plays an important role in anti-HBV ***,most anti-rheumatic drugs exert an inhibitory effect on the body’s immune system,resulting in ***,it is necessary to conduct a comprehensive evaluation based on host factors,viral factors,and drug *** this paper,we summarize the mechanism of HBVr,the risk of HBVr caused by anti-rheumatic drugs,and the appropriate diagnosis and treatment process for ra patients so that clinicians can have a more comprehensive understanding of HBVr in ra patients.

关键词： Rheumatoid arthritis Hepatitis B virus reactivation Disease-modifying antirheumatic drugs Risk factors

Assessments on surface water resources and their vulnerability and adaptability in China

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Advances in Climate Change Research 2020年第4期11卷 381-391页

作者： QIN Jia DING Yong-Jian ZHAO Qiu-Dong WANG Shao-Ping CHANG ya-Ping State Key Laboratory of Cryospheric Sciences Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou730000China Key Laboratory of Eco-Hydrology Inland River Basin Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou730000China University of Chinese Academy of Sciences Beijing100049China

A clear understanding of the changes of water resources under the background of environmental changes is of great significance for scientific management and utilization of water resources in *** study systematically analyzed the spatialetemporal variations of surface water resources in China since *** vulnerability in current(2010s)and its trends from 2000 to late-2010s in different regions of China were also *** addition,the correspondingly adaptive measures to counter regional risks to water resources were *** concluded that the runoff of major rivers had been decreasing in eastern China and increasing in western China during *** the arid area of Northwest China,the alpine runoff has shown an overall upward trend since the late-1990s/early-2000s,with a 10%-25% increase caused by the increase of glacial meltwater and *** the runoff of each hydrological station in the 2000s-2010s was 34.7% lower than that in the 1950se2010s on *** increases in precipitation and glacial meltwater with global warming caused a rapid expansion of lakes in the Qinghai-Tibet Plateau and Xinjiang,thus leading to an increase in total area and water quantity of lakes in China from 1995 to *** mean contribution rates of climate change and human activity to runoff change in river basins of China were 53.5% and 46.5%,respectively,during the period of *** driving factor of runoff change in many river basins has gradually changed from climate change(1950s-2000)to human activity(2000-2018).During 2000-2018,the contributions of human activities to runoff change were 50%-80% in major rivers of eastern *** vulnerability in most areas of Northwest China and North China is generally high,with the vulnerability index greater than ***,in Northeast,East,South,and Central China,it is lower or not *** Southwest China,the vulnerability varies greatly with Yunnan and Sichuan relatively low while Chon

关键词： Runoff change Lake area Surface water vulnerability Adaptation measures China