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Balancing early detection and over-screening:Evaluating colonoscopy's role in shaping colorectal cancer trends in Korea

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World Journal of Gastrointestinal Oncology 2025年第3期17卷 474-478页

作者： Di-Ping Luo Bo-tao Xu Hui zhang Tie-Fei He Department of Vascular Surgery Zhuji People's HospitalZhuji 311800Zhejiang ProvinceChina Department of Cardiothoracic Surgery Zhuji People's HospitalZhuji 311800Zhejiang ProvinceChina Department of Emergency Surgery Zhuji People's HospitalZhuji 311800Zhejiang ProvinceChina

This study discusses the impact of the increasing use of colonoscopy on the trends of colorectal cancer(CRC)in *** views are raised on the research methods and conclusions of Kim et *** emphasizes the need to carefully consider the balance between the benefits of early detection and the risks of *** letter also suggests directions for future research and policy considerations in the field of CRC screening and prevention in Korea.

关键词： Colorectal cancer Colonoscopy Screening policies Early detection Overscreening Artificial intelligence Molecular biomarkers Oncology research

Benchmark Datasets for Fluid Flow Analysis

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CSEE Journal of Power and Energy Systems 2025年第1期11卷 365-379页

作者： Wenhao Jia tao Ding Ouzhu Han Chenggang Mu Hongji zhang Department of Electrical Engineering Xi'an Jiaotong UniversityXi'anShaanxi710049China

Fluid flow analysis, such as gas flow analysis, water flow analysis, etc., is a fundamental problem in integrated energy systems (IES). Datasets are significant for researchers to test their proposed models and algorithms for fluid flow analysis. In this paper, we provide multiple benchmark datasets of fluid systems with detailed topology and operation information, such as data of fluid supply, fluid demand, pipes, valves, compressors/pumps, physical operation limits, etc. The provided benchmark datasets have synthetic and practical fluid systems of different scales, including gas systems with numbers of nodes ranging from 11 to 4197 and water systems with numbers of nodes ranging from 7 to 1894. Then, the data format of the datasets is described. Finally, fluid flow results on different benchmark systems under several typical scenarios are analyzed.

关键词： Benchmark systems dataset fluid flow analysis gas systems water systems

Thermal Contact Resistance and Heat Transfer Enhancement Mechanisms at Non-Smooth Contact Interfaces

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Journal of Thermal Science 2025年第02期 465-497页

作者： WANG Yifan SUN Xiaoxia KANG Huifang MA Xinglong zhang tao School of Mechanical Engineering Beijing Institute of Technology China North Vehicle Research Institute

As an important and effective indicator of contact heat transfer,thermal contact resistance is a widespread phenomenon in *** can directly affect product reliability,full-load performance,power consumption and even life cycle in energy,aerospace,electronic packaging,cryogenic refrigeration,***,enhancing the interface heat transfer and suppressing thermal contact resistance have become increasingly *** this background,this paper seeks to elaborate on conceptions of thermal contact resistance and the ways to reduce *** reviewing the existing methods of measuring thermal contact resistance and characterizing the interface morphology,we highlight the theoretical underpinnings of thermal contact resistance,including the two-dimensional mathematic characteristics of the contact interface and the theoretical and empirical models for quantifying *** categories of influencing factors,i.e.,thermal,geometrical and mechanical states,are then *** on the macroscopic formation mechanism,the paper summarizes the existing methods for suppressing thermal contact resistance,with close attention paid to polymer composite thermal interfacial materials and metal interfacial materials filled with high thermal conductivity *** light of the findings,this review provides five promising directions for future research on thermal contact *** suggests that the failure modes and service life of interface materials are essential to apply such technologies to suppress thermal contact resistance in *** review will be a guide for future research in thermal contact resistance and for the widespread use of composite interface materials.

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Wideband high gain millimeter wave antenna based on wavy power divider for millimeter wave radar sensor

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The Journal of China Universities of Posts and Telecommunications 2025年

作者： zhang Shuanggen Yu tao Wang Yulan Zhou Ran Cheng Zhihua School of Integrated Circuit Science and Engineering， Tianjin University of Technology

In this paper， a broadband high gain millimeter wave radar array antenna based on a wavy power divider is proposed. The radar antenna comprises a wavy power divider and a 10-element array antenna. By adjusting the wavy radius of the power divider， the surface current of the power divider is altered， resulting in better impedance matching with the antenna. This ultimately leads to a significant improvement in bandwidth performance. The 410 millimeter wave radar antenna loaded with wavy power divider exhibits an approximate enhancement of 3 GHz compared to traditional microstrip power divider antennas， and an average gain increase of 2.42 dB within the vehicle millimeter wave radar frequency band relative to the improved gradient power divider structure. The 410 millimeter wave radar antenna loaded with wavy power divider possesses the characteristics of high gain and broad bandwidth.

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Establishment of goat mammary organoid cultures modeling the mammary gland development and lactation

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Journal of Animal Science and Biotechnology 2025年第1期16卷 193-205页

作者： Lei Jia Wenying zhang tao Luo Yongtao Li Jianhong Shu Julie Strand Yuan Yue Stig Purup Jianxin Liu Hengbo Shi Zhejiang Key Laboratory of Cow Genetic Improvement&Milk Quality Research Institute of Dairy ScienceCollege of Animal SciencesZhejiang UniversityHangzhou 310058China College of Life Sciences and Medicine Zhejiang Sci-Tech UniversityHangzhou 310018China Department of Animal and Veterinary Sciences Aarhus UniversityTjele DK‑8830Denmark Ministry of Education Key Laboratory of Molecular Animal Nutrition Zhejiang UniversityHangzhou 310058China

Background Although several cell culture systems have been developed to investigate the function of the mam-mary gland in dairy livestock,they have potential limitations,such as the loss of alveolar structure or genetic and phe-notypic differences from their native *** these challenges is crucial for lactation *** of protocols to establish lactating organoid of livestock represents a promising goal for the *** this study,we developed a protocol to establish a culture system for mammary organoids in dairy goats to model the mammary gland development and lactation *** The organoids cultured within an extracellular matrix gel maintained a bilayer structure that closely resem-bled the native architecture of mammary *** expansion of mammary organoids was significantly promoted by growth factors containing epidermal growth factor and fibroblast growth factor 2 whereas the proliferative index of the organoids was significantly inhibited by the treatment with WNT *** stimulation with a lactogenic medium containing prolactin,the mammary organoids exhibited efficient lactation,characterized by the accumu-lation of lipid droplets in the lumen *** lactation could be sustained for more than 3 ***,the expression patterns of genes related to fatty acid synthesis and milk proteins in lactating organoids closely mirrored those observed in mammary *** observations were confirmed by data from proteomic analysis that the bulk of milk proteins was produced in the lactating *** This study is the first to establish a mammary organoid culture system modeling the mammary gland development and lactation process in *** efficient induction of lactation in ruminant mammary organoids holds promises for advancing the field of cell-based milk bio-manufacture in the food industry.

关键词： Cell-based milk production Lactation Mammary gland Organoid

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Enhanced rate capability and cycle stability of Ti2C MXene for sodium storage through an aniline molecules welding strategy

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Tungsten 2025年第1期7卷 161-171页

作者： Hao Chen ya-Qin Wang Dong-Ting zhang Bei Zhao Min-Peng Li Chen-yang Li Tian-Peng Xu Mao-Cheng Liu State Key Laboratory of Advanced Processing and Recycling of Non-Ferrous Metals Lanzhou University of Technology School of Materials Science and Engineering Lanzhou University of Technology School of Computer and Communication Technology Lanzhou University of Technology

MXenes obtained significant attention in the field of energy storage devices due to their characteristic layered structure,modifiable surface functional groups,large electrochemically active surface,and regulable interlayer ***,the self-restacking and sluggish ions diffusion kinetics performance of MXenes during the alkali metal ions insertion/extraction process severely impedes their cycle stability and rate *** paper proposes an aniline molecule welding strategy for welding p-phenylenediamine（PPDA） into the interlayers of Ti2C through a dehydration condensation *** welded PPDA molecules can contribute pillar effect to the layered structure of *** pillar effect effectively maintains the structural stability during the sodium ions insertion/extraction process and effectively expands the interlayer spacing of Ti2C from 1.16 to 1.38 nm,thereby enhancing ions diffusion kinetics performance and improving the long-term cycle *** Ti2C-PPDA demonstrates outstanding Na+storage capability,exhibiting a specific capacity of 100.2 mAh·g-1at a current density of 0.1 A·g-1over 960 cycles and delivering a remarkable rate capability 81.2 mAh·g-1at a current density of 5 A·*** study demonstrates that expanding interlayer spacing is a promising strategy to enhance the Na+storage capacity and improve long-term cycling stability,which provides significant guidance for the design of two-dimensional Na+storage materials with high-rate capability and cycle stability.

关键词： Diffusion kinetics Expanding interlayer spacing Rate capability Sodium ions storage Ti2C

Prompt fission neutron uranium logging(Ⅱ):dead-time effect of the neutron time spectrum

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Nuclear Science and Techniques 2025年第2期36卷 82-94页

作者： yan zhang Chi Liu Shi-Liang Liu Hao-Ran zhang Hai-tao Wang Jin-Hui Qu Wen-Xing Hu Ren-Bo Wang Bin Tang National Key Laboratory of Uranium Resources Exploration-Mining and Nuclear Remote Sensing East China University of TechnologyNanchang 330013China Fundamental Science on Radioactive Geology and Exploration Technology Laboratory East China University of TechnologyNanchang 330013China

The acquisition of neutron time spectrum data plays a pivotal role in the precise quantification of uranium via prompt fission neutron uranium logging(PFNUL).However,the impact of the detector dead-time effect remains paramount in the accurate acquisition of the neutron time ***,it is imperative for neutron logging instruments to establish a dead-time correction method that is not only uncomplicated but also practical and caters to various logging *** study has formulated an innovative equation for determining dead time and introduced a dead-time correction method for the neutron time spectrum,called the“dual flux method.”Using this approach,a logging instrument captures two neutron time spectra under disparate neutron *** carefully selecting specific“windows”on the neutron time spectrum,the dead time can be accurately *** substantiate its efficacy and discern the influencing factors,experiments were conducted utilizing a deuterium-tritium(D-T)neutron source,a Helium-3(3He)detector,and polyethylene shielding to collate and analyze the neutron time spectrum under varying neutron fluxes(at high voltages).The findings underscore that the“height”and“spacing”of the two windows are the most pivotal influencing ***,the“height”(fd)should surpass 2,and the“spacing”twd should exceed 200μ*** dead time of the 3 He detector determined in the experiment was 7.35μ*** the dead-time correction,the deviation of the decay coefficients from the theoretical values for the neutron time spectrum under varying neutron fluxes decreased from 12.4%to within 5%.Similarly,for the PFNUL instrument,the deviation in the decay coefficients decreased from 22.94 to 0.49%after correcting for the dead-time *** results demonstrate the exceptional efficacy of the proposed method in ensuring precise uranium *** dual flux method was experimentally validated as a universal approach applicable to pulsed neutron logging instrumen

关键词： PFNUL Neutron time spectrum Dead time Pulsed source Correction method

Unintentional emissions of polychlorinated naphthalenes in China:Sources,composition,and historical trends

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Journal of Environmental Sciences 2025年第2期148卷 221-229页

作者： Ye Huang Lin Huang Ying Li Nazupar Sidikjan Yunshan zhang yan Chen yangmin Chen Ye Li Wei Du Long Chen yanWu Shanshan zhang Jing yang Wenjun Meng Guofeng Shen Min Liu Shu tao Key Laboratory of Geographic Information Science of the Ministry of Education School of Geographic SciencesEast China Normal UniversityShanghai 200241China Yunnan Provincial Key Laboratory of Soil Carbon Sequestration and Pollution Control Faculty of Environmental Science&EngineeringKunming University of Science&TechnologyKunming 650500China Laboratory of Earth Surface Processes College of Urban and Environmental SciencePeking UniversityBeijing 100871China

Polychlorinated naphthalenes(PCNs)are detrimental to human health and the *** the commercial production of PCNs banned,unintentional releases have emerged as a significant environmental ***,relevant information is still *** this study,provincial emissions for eight PCNs homologues from 37 sources in the Chinese mainland during the period of 1960-2019 were estimated based on a source-specific and time-varying emission factor *** results showed that the total PCNs emissions in 2019 reached 757.0 kg with Hebei ranked at the top among all the provinces and iron&steel industry as the biggest ***-chlorinated PCNs comprised 90%of emissions by mass,while highly chlorinated PCNs dominated in terms of toxicity,highlighting divergent priorities for mitigating emissions and safeguarding human *** emissions showed an overall upward trend from 1960 to 2019 driven by emission increase from iron&steel industry in terms of source,and from North China and East China in terms of geographic ***-capita emissions followed an inverted U-shaped environmental Kuznets curvewhile emission intensities decreased with increasing per-capita Gross Domestic Product(GDP)following a nearly linear pattern when log-transformed.

关键词： PCNs Emission inventory Emission factor Composition profile Emission intensity Chinese mainland

The CmCYC2 factors regulated the different biosynthesis and distribution of phenolic compounds in the capitulum of Chrysanthemum morifolium‘Hangju’

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Horticultural Plant Journal 2025年第1期11卷 336-350页

作者： Feng yang Qiaosheng Guo Qingjun Zou Man zhang Yong Su Shuyan Yu Jingzhe Pu tao Wang Institute of Chinese Medicinal Materials Nanjing Agricultural UniversityNanjingJiangsu 210095China NMPA Key Laboratory for Quality Research and Evaluation of Traditional Chinese Medicine Anhui Institute for Food and Drug ControlHefeiAnhui 230051China

Chrysanthemum morifolium *** an important industrial crop with a high medicinal value,whose capitulum consists of ray and disc florets containing numerous bioactive components,such as flavonoids and phenolic ***,the distribution and accumulations of the bioactive metabolites in florets of Chrysanthemum morifolium were ***,the ray and disc florets of Chrysanthemum morifolium were separated for comparing the bioactive *** contents of phenolic compounds and antioxidant activities were significantly different between the two *** metabolomic analysis identified 203 and 241 differential metabolites between ray and disc florets at two flowering *** derivatives of quercetin,isorhamnetin,tricin,and caffeoylquinic acid were enriched in the disc florets,while apigenin,kaempferol,acacetin,and their glycosides mainly accumulated in the ray ***,the results of transcriptome and qRT-PCR suggested that the F3H,F3'H,and FLS genes highly expressed in disc florets,while the FNS gene was well expressed in ray florets,which explained the different distribution of phenolic compounds between ray and disc ***,the expression of CmCYC2 genes was found to be significantly related to the distribution of flavones by correlation *** was proved by the luciferase reporter assay that CmCYC2a and CmCYC2d factors could bind and activate the CmFNS promoter to regulate the flavones biosynthesis in ray *** results revealed the significant difference of metabolite contents and gene expression profile between ray and disc floret in Chrysanthemum morifolium and demonstrated that the quality of Chrysanthemum morifolium‘Hangju'was closely relevant to its flower morphology.

关键词： Chrysanthemum morifolium Ramat. Ray florets Disc florets Multi-omics analysis Flavonoids Phenolic acids

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