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Numerical Prediction of Compound Layer Growth of Steel En40B during Plasma Nitriding

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材料热处理学报 2004年第5B期25卷 776-778页

作者： DAIya-nan yaNMu-fu LEITing-quan WUKun SchoolofMaterialsScienceandEngineering HarbinInstituteofTechnologyHarbinChina

This paper deals with the kinetics of compound layer growth of steel En40B plasmas nitrided at 520°C for different time and establishes the corresponding mathematical model based on the thermodynamics and kinetics of nitrogen diffusion process. The results show that the compound layer consists of dual phases e (Fe2-3N) and / (Fe4N) and its thickness increases with increasing nitriding time. The calculated data indicate that the critical concentration between compound layer and diffusion one is about 0.82wt%. The computer simulation results demonstrate that predicted compound layer thickness agrees with the measured data.

关键词：等离子渗氮 En40B钢化合层计算机模拟

3D Fe-Rich Phases Evolution and Its Effects on the Fracture Behavior of Al-7.0Si-1.2Fe Alloys by Mn Neutralization

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Acta Metallurgica Sinica(English Letters) 2022年第1期35卷 163-175页

作者： Dong-fu Song Yu-Liang Zhao Zhi Wang Yi-Wang Jia Dao-Xi Li ya-nan fu Da-Tong Zhang Wei-Wen Zhang National Engineering Research Center of Near-Net-Shape Forming for Metallic Materials South China University of TechnologyGuangzhou510641China Guangdong Provincial Key Laboratory of Metal Toughening Technology and Application Institute of New MaterialsGuangdong Academy of SciencesGuangzhou510650China School of Mechanical Engineering Dongguan University of TechnologyDongguan523808China Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai201204China

The evolution of the 3D Fe-rich phases of Al-7.0Si-1.2Fe alloys with different Mn contents was visualized and characterized using synchrotron X-ray computed tomography,and the effect of Fe-rich phases with typical morphologies on the fracture behavior during tensile testing was *** results showed that the Fe-rich phase changed from platelet-likeβ-Al_(5) Fe Si intoα-Al_(15)(Fe Mn)_(3)Si_(2)with various morphologies after the addition of *** Mn addition not only significantly reduced the volume fraction,equivalent diameter and interconnectivity of the Fe-rich phase but also greatly increased the sphericity,surface thickness,and distribution of the mean curvature and surface ***,the equivalent diameter ofα-Al_(15)(FeMn)_(3)Si_(2)had an inverse exponential function relationship with its *** 3D morphology ofα-Al_(15)(FeMn)_(3)Si_(2)can be summarized as massive and regular polyhedrons,hollow and regular polyhedrons,and multibranched *** fraction of the different 3D morphologies in each alloy is related to the Mn content,where excess Mn increased the number and volume fraction of the large Fe-rich particles with a low *** ductility of each alloy was significantly improved by the addition of Mn but gradually decreased when the Mn/Fe ratio exceeded *** increase in largeα-Al_(15)(Mn Fe)_(3)Si_(2)with a low sphericity was the main reason for the decreased ductility of alloys with a high Mn content.

关键词： Synchrotron X-ray tomography Fe-rich phase 3D morphology Fracture behavior

Real-time Observation on Coarsening of Second-Phase Droplets in Al–Bi Immiscible Alloy Using Synchrotron Radiation X-ray Imaging Technology

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Acta Metallurgica Sinica(English Letters) 2015年第7期28卷 940-945页

作者： Hui-Jun Kang Peng Zhou Fei Cao Jing Zhu ya-nan fu Wan-Xia Huang Ti-Qiao Xiao Tong-Min Wang Key Laboratory of Materials Modification By Laser Ion and Electron Beams (Ministry of Education)School of Materials Science and EngineeringDalian University of Technology Dalian Marine Propeller Co.Ltd Shanghai Institute of Applied Physics Chinese Academy of Sciences Institute of High Energy Physics Chinese Academy of Sciences

The coarsening process of second-phase droplet in solidifying Al-20 wt% Bi immiscible alloy is in situ studied using synchrotron radiation imaging *** collision-induced coarsening and Ostwald coarsening phenomena are directly observed and *** is found that through observation,collision-induced coarsening phenomenon occurs between droplets with little difference in radius,while Ostwald coarsening phenomenon occurs among droplets with much difference in ***,the coarsening rate of Ostwald coarsening is much higher than that of collision-induced coarsening.

关键词： Al alloys Coarsening Secondary phase Droplet particles

The new X-ray imaging and biomedical application beamline BL13HB at SSRF

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Nuclear Science and Techniques 2023年第12期34卷 190-205页

作者： Jian‑Feng Ji Han Guo yan‑Ling Xue Rong‑Chang Chen ya‑nan fu Guo‑Hao Du Biao Deng Hong‑Lan Xie Ti‑Qiao Xiao Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China Shanghai Institute of Applied Physics China Academy of ScienceShanghai 201800China

A new X-ray imaging and biomedical application beamline(BL13HB)has been implemented at the Shanghai Radiation Synchrotron Facility(SSRF)as an upgrade to the old X-ray imaging and biomedical application beamline(BL13W1).This is part of the Phase II construction project of the *** BL13HB is dedicated to 2D and 3D static and dynamic X-ray imaging,with a field of view of up to 48.5 mm×5.2 mm and spatial resolution as high as 0.8μm.A super-bending magnet is used as the X-ray source in BL13HB,which has a maximum magnetic field of 2.293 *** energy range of monochromatic X-ray photons from a double-multiplayer monochromator was 8–40 keV,and the white beam mode was provided on the beamline for dynamic X-ray imaging and dynamic X-ray *** maintaining the previous experimental setup of BL13W1,new equipment was added to the beamline experimental *** beamline is equipped with different sets of X-ray imaging detectors for several experimental methods such as micro-CT,dynamic micro-CT,and pair distribution *** experimental station of BL13HB is designed specifically for various in situ dynamic experiments,and BL13HB has been open to users since June 2021.

关键词： X-ray imaging Dynamic micro-CT Shanghai Synchrotron Radiation Facility

Spatiotemporally dynamic therapy with shape-adaptive drug-gel for the improvement of tissue regeneration with ordered structure

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Bioactive Materials 2022年第2期7卷 165-176页

作者： ya-nan fu Yongsan Li Bo Deng Yingjie Yu Fang Liu Lei Wang Guang Chen Lei Tao Yen Wei Xing Wang Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing Laboratory of Biomedical MaterialsBeijing University of Chemical TechnologyBeijing100029China Department of Oncology of Integrative Chinese and Western Medicine China-Japan Friendship HospitalBeijing100029China Institute of Translational Medicine Shenzhen Second People’s HospitalThe First Affiliated Hospital of Shenzhen UniversityHealth Science CenterShenzhen518035China The Key Laboratory of Bioorganic Phosphorus Chemistry&Chemical Biology(Ministry of Education) Department of ChemistryTsinghua UniversityBeijing100084China

A spatiotemporally dynamic therapy(SDT)is proposed as a powerful therapeutic modality that provides spatially dynamic responses of drug-carriers for adapting to the wound ***,dynamic chitosan-poly(ethylene glycol)(CP)Schiff-base linkages are employed to perform SDT by directly converting a liquid drug Kangfuxin(KFX)into a gel *** obtained KFX-CP drug-gel with shape-adaptive property is used to treat a representative oral mucositis(OM)model in a spatiotemporally dynamic *** KFX-CP drug-gel creates an instructive microenvironment to regulate signaling biomolecules and endogenous cells behavior,thereby promoting OM healing by the rule of dynamically adjusting shape to fit the irregular OM regions first,and then provides space for tissue regeneration,over KFX potion control and the general hydrogel group of CP hydrogel and *** interestingly,the regenerated tissue has ordered structure like healthy ***,the SDT provides a new approach for the design of next generation of wound dressing and tissue engineering materials.

关键词： Spatiotemporally dynamic therapy Drug-gel Shape-adaptive Tissue regeneration Ordered structure

Methodology development and application of X-ray imaging beamline at SSRF

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Nuclear Science and Techniques 2020年第10期31卷 74-94页

作者： Hong-Lan Xie Biao Deng Guo-Hao Du ya-nan fu Han Guo yan-Ling Xue Guan-Yun Peng Fen Tao Ling Zhang Ti-Qiao Xiao Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China Shanghai Synchrotron Radiation Facility(SSRF) Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China

This paper introduces some latest developments regarding the X-ray imaging methodology and applications of the X-ray imaging and biomedical application beamline(BL13W1)at Shanghai Synchrotron Radiation Facility in the past 5 *** photon energy range of the beamline is 8–72.5 *** sets of X-ray imaging detectors with different pixel sizes(0.19–24 lm)are used to realize X-ray microcomputed tomography(X-ray micro-CT)and X-ray in-line phase-contrast *** satisfy the requirements of user experiments,new X-ray imaging methods and image processing techniques are *** vivo dynamic micro-CT experiments with living insects are performed in 0.5 s(sampling rate of 2 Hz,2 tomograms/s)with a monochromatic beam from a wiggler source and in 40 ms(sampling rate of 25 Hz,25 tomograms/s)with a white beam from a bending magnet source.A new X-ray imaging method known as move contrast X-ray imaging is proposed,with which blood flow and moving tissues in raw images can be distinguished according to their moving frequencies in the time ***,X-ray speckle-tracking imaging with twice exposures to eliminate the edge enhancement effect is developed.A high-precision quantification method is realized to measure complex three-dimensional blood vessels obtained via X-ray micro-CT.X-ray imaging methods such as three-dimensional X-ray diffraction microscopy,small-angle X-ray scattering CT,and X-ray fluorescence CT are developed,in which the X-ray micro-CT imaging method is combined with other contrast mechanisms such as diffraction,scattering,and fluorescence contrasts ***,an X-ray nano-CT experiment is performed with a 100 nm spatial *** user experimental results from the fields of material science,biomedicine,paleontology,physics,chemistry,and environmental science obtained on the beamline are provided.

关键词： X-ray imaging X-ray in-line phase-contrast imaging X-ray micro-CT Dynamic micro-CT X-ray speckle-tracking imaging 3DXRD SAXS-CT X-ray fluorescence CT X-ray nano-CT Move contrast X-ray imaging

Acupuncture and/or moxibustion for the treatment of lumbar disc herniation:quality assessment of systematic reviews

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Traditional Medicine Research 2020年第4期5卷 282-294页

作者： Zi-Han Yin Chao-Xi Zhu Gui-Xing Xu Cheng Ying Ai-Ling Huang ya-nan fu Jiao Chen Ling Zhao Fan-Rong Liang Chengdu University of Traditional Chinese Medicine Chengdu 610075China

Objective:In the current systematic review on acupuncture and/or moxibustion for lumbar disc herniation(LDH),we evaluated the methodology and quality of evidence and reports to provide necessary information for accurate clinical decision-making regarding acupuncture and/or moxibustion for ***:From databases such as CBM(Chinese biomedical literature database),VIP(China science and technology journal database),CNKI(China national knowledge infrastructure),WF(Wanfang database),Web of Science,Embase,Medline,and Cochrane Library,systematic reviews on acupuncture and/or moxibustion for LDH were retrieved,and the methodological quality of the literature was evaluated according to the assessment of multiple systematic reviews(AMSTAR)***,the grading of recommendations assessment,development and evaluation(GRADE)system was used to grade the quality of evidence and the preferred reporting items for systematic reviews and meta-analyses(PRISMA)statement to evaluate the quality of the ***:A total of 18 systematic reviews were included,and the conclusion is that acupuncture and/or moxibustion have some advantages in terms of efficacy and safety with regard to LDH *** to the AMSTAR score,there were 4 high-quality studies,13 moderate-quality studies,and 1 low-quality *** showed that quality of evidence such as total effective rate of LDH and VAS was low and that of other forms of evidence was *** PRISMA statement showed that 8 articles were in line with 20 or more of the 27 items,and 10 articles were in line with 10-19 of the 27 ***:At present,acupuncture and/or moxibustion for LDH has a good curative *** importantly,its methodological quality was of moderate level and the report quality was generally good and relatively ***,the poor quality of the original research results was reflected in the quality of *** studies are needed to make sure whether acupuncture is more effective

关键词： Lumbar disc herniation Acupuncture therapy Overview of systematic reviews AMSTAR GRADE PRISMA.

Artificial intelligence is transforming the research paradigm of environmental science and engineering

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Environmental Science and Ecotechnology 2024年第3期19卷 1-3页

作者： Xu Wang Guangtao fu nan-Qi Ren State Key Laboratory of Urban Water Resource and Environment School of Civil and Environmental EngineeringHarbin Institute of TechnologyShenzhenShenzhen518055China Centre for Water Systems College of EngineeringMathematics and Physical SciencesUniversity of ExeterExeterEX44QFUnited Kingdom

Artificial intelligence(AI),particularly through its datacrunching powerhouse,machine learning(ML),is revolutionizing the way we approach high-throughput data to obtain underlying mechanisms,characterizing,forecasting,and making evidencebased decisions in many fundamental science ***,a pressing question has emerged in the scientific community in recent years:How can we effectively interpret AI algorithms and gauge their contributions to fundamental research?

关键词： has gauge forecasting

Development and validation of a novel non-invasive test for diagnosing nonalcoholic fatty liver disease in Chinese children

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World Journal of Pediatrics 2024年第4期20卷 413-421页

作者： Zhe-Wen Qin Qian-nan Ren Hong-Xi Zhang ya-Ru Liu Ke Huang Wei Wu Guan-Ping Dong yan Ni Jun-Fen fu Division of Endocrinology National Clinical Research Center for Child HealthNational Children’s Regional Medical CenterThe Children’s HospitalDepartment of EndocrinologyNational Clinical Research Center for Child HealthNational Children’s Regional Medical CenterThe Children’s HospitalZhejiang University School of MedicineHangzhou310052China

With the exploding prevalence of obesity,many children are at risk of developing nonalcoholic fatty liver *** anthropometric and laboratory parameters,our study aimed to develop a model to quantitatively evaluate liver fat content(LFC)in children with *** A well-characterized cohort of 181 children between 5 and 16 years of age were recruited to the study in the Endocrinology Department as the derivation *** external validation cohort comprised 77 *** assessment of liver fat content was performed using proton magnetic resonance *** and laboratory metrics were measured in all subjects.B-ultrasound examination was carried out in the external validation *** Kruskal-Wallis test,Spearman bivariate correlation analyses,univariable linear regressions and multivariable linear regression were used to build the optimal predictive *** The model was based on indicators including alanine aminotransferase,homeostasis model assessment of insulin resistance,triglycerides,waist circumference and Tanner *** adjusted R^(2)of the model was 0.589,which presented high sensitivity and specificity both in internal[sensitivity of 0.824,specificity of 0.900,area under curve(AUC)of 0.900 with a 95%confidence interval:0.783–1.000]and external validation(sensitivity of 0.918 and specificity of 0.821,AUC of 0.901 with a 95%confidence interval:0.818–0.984).Conclusions Our model based on five clinical indicators was simple,non-invasive,and inexpensive;it had high sensitivity and specificity in predicting LFC in ***,it may be useful for identifying children with obesity who are at risk for developing nonalcoholic fatty liver disease.

关键词： Biochemical markers Children Magnetic resonance spectroscopy Nonalcoholic fatty liver disease Pediatric obesity