检索结果-南通市图书馆

Carbon cathode with heteroatom doping and ultrahigh surface area enabling enhanced capacitive behavior for potassium-ion hybrid capacitors

引用

Rare Metals 2024年第5期43卷 2136-2149页

作者： yan Xiong ya-fei zhang Chun-Liu Zhu Lei yang Huan-Yu Liang Jing Shi Jing-Wei Chen Wei-QianTian Shuai Liu Zhi Li Jing-Yi Wu Huan-Lei Wang School of Materials Science and Engineering Ocean University of ChinaQingdao 266100China Department of Chemical and Materials Engineering University of AlbertaEdmontonAB T6G 2V4Canada

Potassium-ion hybrid capacitors(PIHCs)are widely regarded as highly promising energy storage devices,due to their exceptional energy density,impressive power density,and abundant potassium ***,restricted by the inherent capacitive storage mechanism,the carbon cathodes possess a much lower specific capacity than battery-type ***,designing high-performance carbon cathodes is extremely urgent for the development of ***,N,O codoped porous carbon(NOPC)was fabricated through the NaCl hard template method and combined KOH/melamine chemical activation technique,displaying the characteristics of abundant N/O content(4.7 at%/16.9 at%),ultrahigh specific surface area(3092 m^(2)g^(-1))and hierarchical pore *** designed NOPC cathode delivers a high specific capacity(164.4 mAh.g^(-1)at 0.05 A.g^(-1))and superior cyclability(95.1%retention ratio at 2 A·g^(-1)over 2500 cycles).Notably,the adjustable ratio of micropores to mesopores facilitates the achievement of the optimal bal-ance between capacity and rate ***,the pseudocapacitance can be further augmented through the incorporation of N/O functional *** expected,the graphite//NOPC based PIHC possesses a high energy density of 113 Wh·kg-at 747 W·kg^(-1)and excellent capacity retention of 84.4% fter 400 cycles at 1.0 A·g^(-1).This work introduces a novel strategy for designing carbon cathodes that enhances the electrochemical performance of PIHCs.

关键词： Template method N/O co-doping High specific surface area Carbon cathode Potassium-ion capacitors

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Prediction model for hepatitis B e antigen seroconversion in chronic hepatitis B with peginterferon-alfa treated based on a responseguided therapy strategy

引用

World Journal of Hepatology 2024年第3期16卷 405-417页

作者： Pei-Xin zhang Xiao-Wei Zheng ya-fei zhang Jun Ye Wei Li Qian-Qian Tang Jie Zhu Gui-Zhou Zou Zhen-Hua zhang Department of Infectious Diseases The Second Affiliated Hospital of Anhui Medical UniversityHefei 230601Anhui ProvinceChina Department of Infectious Diseases Anhui Provincial HospitalHefei 230000Anhui ProvinceChina Department of Hepatology The Second People’s Hospital of Fuyang CityFuyang 236000Anhui ProvinceChina

BACKGROUND Models for predicting hepatitis B e antigen(HBeAg)seroconversion in patients with HBeAg-positive chronic hepatitis B(CHB)after nucleos(t)ide analog treatment are *** To establish a simple scoring model based on a response-guided therapy(RGT)strategy for predicting HBeAg seroconversion and hepatitis B surface antigen(HBsAg)*** In this study,75 previously treated patients with HBeAg-positive CHB underwent a 52-week peginterferon-alfa(PEG-IFNα)treatment and a 24-wk *** regression analysis was used to assess parameters at baseline,week 12,and week 24 to predict HBeAg seroconversion at 24 wk *** two best predictors at each time point were used to establish a prediction model for PEG-IFNαtherapy *** at each time point that met the corresponding optimal cutoff thresholds were scored as 1 or *** The two most meaningful predictors were HBsAg≤1000 IU/mL and HBeAg≤3 S/CO at baseline,HBsAg≤600 IU/mL and HBeAg≤3 S/CO at week 12,and HBsAg≤300 IU/mL and HBeAg≤2 S/CO at week *** a total score of 0 vs 2 at baseline,week 12,and week 24,the response rates were 23.8%,15.2%,and 11.1%vs 81.8%,80.0%,and 82.4%,respectively,and the HBsAg clearance rates were 2.4%,3.0%,and 0.0%,vs 54.5%,40.0%,and 41.2%,*** We successfully established a predictive model and diagnosis-treatment process using the RGT strategy to predict HBeAg and HBsAg seroconversion in patients with HBeAg-positive CHB undergoing PEG-IFNαtherapy.

关键词： Chronic hepatitis B Hepatitis B e antigen-positive Peginterferon-alfa Prediction model Response-guided therapy strategy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Global trends and hotspots of treatment for nonalcoholic fatty liver disease:A bibliometric and visualization analysis(2010-2023)

引用

世界胃肠病学杂志:英文版 2023年第37期29卷 5339-5360页

作者： Jin-Jin Dai ya-fei zhang Zhen-Hua zhang Department of Infectious Diseases Suzhou Hospital of Anhui Medical UniversitySuzhou 234000Anhui ProvinceChina Department of Infectious Diseases The Second Affiliated Hospital of Anhui Medical UniversityHefei 230601Anhui ProvinceChina

BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is chronic,with its progression leading to liver fibrosis and end-stage *** NAFLD is increasingly common,no treatment guideline has been *** mechanistic studies and drug trials have been conducted for new drug development to treat *** up-to-date overview on the knowledge structure of NAFLD through bibliometrics,focusing on research hotspots,is necessary to reveal the rational and timely directions of development in this *** To research the latest literature and determine the current trends in treatment for *** Publications related to treatment for NAFLD were searched on the Web of Science Core Collection database,from 2010 to ***,CiteSpace,and R package“bibliometrix”were used to conduct this bibliometric *** key information was extracted,and the results of the cluster analysis were based on network data for generating and investigating maps for country,institution,journal,and *** analysis,bursts and cluster analysis,cooccurrence analysis,and trend topic revealed the knowledge structure and research hotspots in this *** Prism 9.***.1.733 and Microsoft Office Excel 2019 were used for data analysis and *** In total,10829 articles from 120 countries(led by China and the United States)and 8785 institutions were *** number of publications related to treatment for NAFLD increased *** China produced the most publications,the United States was the most cited country,and the United Kingdom collaborated the most from an international *** University of California-San Diego,Shanghai Jiao Tong University,and Shanghai University of Traditional Chinese Medicine produced the most publications of all the research *** International Journal of Molecular Sciences was the most frequent journal out of the 1523 total journals,and Hepatology was the most cited and co-cited ***

关键词： Bibliometrics Treatment Therapy Nonalcoholic fatty liver disease Metabolic dysfunction-associated fatty liver disease Historiography analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

MiR-21 Suppresses Anoikis through Targeting PDCD4 and PTEN in Human Esophageal Adenocarcinoma

引用

Current Medical Science 2018年第2期38卷 245-251页

作者： Meng-ya ZHAO La-mei WANG Jing LIU Xing HUANG Jing LIU ya-fei zhang Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China Department of Medical Ultrasound Hubei Provincial Hospital of Traditional Chinese Medicine Wuhan 430060 China Department of Emergency Medicine Zhongnan Hospital of Wuhan University Wuhan 430071 China Department of Gastroenterology Zhongnan Hospital of Wuhan University Wuhan 430071 China

Anoikis is a form of apoptosis induced upon cell detachment from extracellular matrix. It has been determined that acquisition of resistance to anoikis is a critical step for tumor cell metastasis. MiR-21, the most prominent oncomiR, plays an important role in tumor progression. In this study, we revealed that up-regulation of miR-21 in human esophageal adenocarcinoma （EA） is associated with lymph node metastasis and poor survival rate. Because of the established anti-apoptosis effect of miR-21, it is tempting to speculate that miR-21 might contribute to tumor metastasis by regulating anoikis, qRT-PCR analysis demonstrated that miR-21 expression in OE33/AR cells （subpopulation of human EA OE33 cells that acquired resistance to anoikis） was significantly increased. Also, transfection of miR-21 mimics provided OE33 cells resisting to anoikis. By luciferase assays, we verified that PDCD4 and PTEN were the functional targets of miR-21. In mouse model, via tail vein injection experiment, we showed that the metastasis formation of OE33 cells in vivo could be mediated by changing the miR-21 expression pattern. Taken together, our findings suggested that miR-21 was involved in the regulation of anoikis in human EA cells. Targeting miR-21 may provide a novel strategy to prevent metastasis.

关键词： miR-21 anoikis resistance PDCD4 PTEN esophageal adenocarcinoma

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Solution-processed rare-earth thulium oxide with high permittivity for low-voltage transistor and inverters applications

引用

Journal of Rare Earths 2024年第8期42卷 1604-1609,I0007页

作者： Daiming Liu fei Wang Yongtao zhang ya'nan Ding Shandong Engineering Laboratory for Preparation and Application of High-performance Carbon-Materials College of Electromechanical EngineeringQingdao University of Science&TechnologyQingdao266061China College of Electronic and Information Engineering Shandong University of Science and TechnologyQingdao266590China

The use of high-permittivity(high-k) thin films as gate dielectrics is essential in the development of lowpower electronics,In this work,rare-earth thulium oxide(Tm_(2)O_(3)) thin films were prepared by a facile solution process and annealed at various temperatures from 400 to 700℃.The evolution of the physical and dielectric properties of Tm_(2)O_(3) thin film with annealing temperature was *** is demonstrated that the Tm_(2)O_(3) thin film annealed at 600℃ exhibits the optimal performance,including a low leakage current of 3×10^(-10) A/cm^(2),a large areal capacitance of 250 nF/cm^(2) at 100 Hz,and a high permittivity value of *** Tm_(2)O_(3) thin film as a gate insulator was integrated into the thin film transistor(TFT) employing In_(2)O_(3)-based semiconducting *** In_(2)O_(3) TFT with 600℃-annealed Tm_(2)O_(3) dielectric exhibits the superior perfo rmance,with a high I_(on)/I_(off) of 1.65×10^(7),a small subthre shold swing(SS) value of 0.2 V/dec,a V_(TH) of+1.8 V,and a mobility of 1.68 cm^(2)/(V·s).Furthermore,an inverter constructed by connecting the TFT with a resistor exhibits full-swing *** work provides a facile and appealing method for preparing the high-k Tm_(2)O_(3) thin films as alternative gate dielectrics with the potential for use in low-power electronics and logic circuit applications.

关键词： Rare earths Tm_(2)O_(3) Dielectric Transistor Inverter

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dependence of interferogram phase on incident wavenumber and phase stability of Doppler asymmetric spatial heterodyne spectroscopy

引用

Chinese Physics B 2020年第10期29卷 255-260页

作者： ya-fei zhang Yu-Tao Feng Di Fu Peng-Chong Wang Jian Sun Qing-Lan Bai Xi'an Institute of Optics and Precision Mechanics Chinese Academy of SciencesXi'an 710119China University of Chinese Academy of Sciences Beijing 100049China

Instrument drifts introduce additional phase errors into atmospheric wind measurement of Doppler asymmetric spatial heterodyne spectroscopy (DASH). Aiming at the phase sensitivity of DASH to instrument drifts, in this paper we calculate the optical path difference (OPD) and present an accurate formula of DASH interferogram. By controlling variables in computational ray-tracing simulations and laboratory experiments, it is indicated that initial phase is directly determined by incident wavenumber, OPD offset and field of view (FOV). Accordingly, it is indicated that retrieved phase of DASH is sensitive to slight structural change caused by instrument drift, which provides the proof of necessary-to-track and -correct phase errors from instrument drifts.

关键词： atmospheric wind measurement Doppler asymmetric spatial heterodyne spectroscopy optical path difference interference phase

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of exogenous hydrogen sulfide in the nucleus tractus solitarius on gastric motility in rats

引用

World Journal of Gastroenterology 2023年第29期29卷 4557-4570页

作者： Hong-Zhao Sun Chen-Yu Li Yuan Shi Jin-Jin Li Yi-ya Wang Li-Na Han Lu-Jie Zhu ya-fei zhang College of Life Science Qi Lu Normal UniversityZhangqiu 250200Shandong ProvinceChina

BACKGROUND Hydrogen sulfide(H2S)is a recently discovered gaseous neurotransmitter in the nervous and gastrointestinal *** exerts its effects through multiple signaling pathways,impacting various physiological *** nucleus tractus solitarius(NTS),a vital nucleus involved in visceral sensation,was investigated in this study to understand the role of H2S in regulating gastric function in *** To examine whether H2S affects the nuclear factor kappa-B(NF-κB)and transient receptor potential vanilloid 1 pathways and the neurokinin 1(NK1)receptor in the *** Immunohistochemical and fluorescent double-labeling techniques were employed to identify cystathionine beta-synthase(CBS)and c-Fos co-expressed positive neurons in the NTS during rat *** motility curves were recorded by inserting a pressure-sensing balloon into the pylorus through the stomach *** in gastric motility were observed before and after injecting different doses of NaHS(4 nmol and 8 nmol),physiological saline,Capsazepine(4 nmol)+NaHS(4 nmol),pyrrolidine dithiocarbamate(PDTC,4 nmol)+NaHS(4 nmol),and L703606(4 nmol)+NaHS(4 nmol).RESULTS We identified a significant increase in the co-expression of c-Fos and CBS positive neurons in the NTS after 1 h and 3 h of restraint water-immersion stress compared to the expressions observed in the control ***-NTS injection of NaHS at different doses significantly inhibited gastric motility in rats(P0.05).CONCLUSION NTS contains neurons co-expressing CBS and c-Fos,and the injection of NaHS into the NTS can suppress gastric motility in *** effect may be mediated by activating TRPV1 and NK1 receptors via the NF-κB channel.

关键词： Nucleus tractus solitarius Hydrogen sulfide Gastric motility Nuclear factor kappa-B Transient receptor potential vanilloid 1

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Postoperative survival analysis and prognostic nomogram model for patients with portal hypertension

引用

World Journal of Gastroenterology 2018年第39期24卷 4499-4509页

作者： ya-fei zhang Hong Ji Hong-Wei Lu Le Lu Lei Wang Jin-Long Wang Yi-Ming Li Department of General Surgery the Second Affiliated Hospital of Xi’an Jiaotong University

AIM To analyse the postoperative survival of patients with portal hypertension and determine the factors that influence survival and construct *** We retrospectively followed 1045 patients who underwent splenectomy plus pericardial devascularisation(SPD) between January 2002 and December 2017. Two SPD types are used in our department: splenectomy plus simplified pericardial devascularisation(SSPD) and splenectomy plus traditional pericardial devascularisation(STPD). The Kaplan-Meier method and Cox regression analysis were used to evaluate the prognostic effects of multiple parameters on overall survival(OS), diseasespecific survival(DSS) and bleeding-free survival(BFS). Significant prognostic factors were combined to build nomograms to predict the survival rate of individual *** Five hundred and fifty-seven(53.30%) patients weresuccessfully followed with 192 in the SSPD group and 365 in the STPD group; 93(16.70%) patients died, of whom 42(7.54%) died due to bleeding. Postoperative bleeding was observed in 84(15.10%) patients. The 5-and 10-year OS, DSS and BFS rates in the group of patients who underwent SSPD were not significantly different from those in patients who underwent STPD. Independent prognostic factors for OS were age, operative time, alanine transaminase level and albumin-bilirubin score. Independent prognostic factors for BFS were male sex, age, intraoperative blood loss and time to first flatus. Independent prognostic factors for DSS were the Comprehensive Complication Index and age. These characteristics were used to establish nomograms, which showed good accuracy in predicting 1-, 3-and 5-year OS and *** SSPD achieves or surpasses the long-term survival effect of traditional pericardial devascularisation and is worthy of clinical promotion and application. Nomograms are effective at predicting prognosis.

关键词： Nomogram Portal hypertension Pericardial devascularisation Survival analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comparison of simplified and traditional pericardial devascularisation combined with splenectomy for the treatment of portal hypertension

引用

World Journal of Clinical Cases 2018年第6期6卷 99-109页

作者： ya-fei zhang Hong Ji Hong-Wei Lu Le Lu Lei Wang Jin-Long Wang Yi-Ming Li Department of General Surgery the Second Affiliated Hospital of Xi’an Jiaotong University

AIM To compare the clinical outcomes of patients with portal hypertension(PH) who underwent treatment with splenectomy plus simplified pericardial devascularisation(SSPD) or splenectomy plus traditional pericardial devascularisation(STPD).METHODS We conducted a single-centre retrospective study of 1045 PH patients treated with either SSPD(S Group, 357 patients) or STPD(T Group, 688 patients) between January 2002 and February 2017. In all, 37 clinical indicators were compared to evaluate the efficacy of *** Perioperative indicators in the S Group were significantly better than those in the T Group(P < 0.05). In both groups, the postoperative long-term portal vein diameter and Model for End-Stage Liver Disease score were significantly lower than those in the preoperative and postoperative short-term groups(P< 0.05). The incidence of complications in the S Group was significantly lower than that in the T Group(P < 0.05). Compared to the T Group, postoperative shortterm WBC(white blood cell) and platelet counts were significantly lower and the short-term Hb(haemoglobin) level was significantly higher in the S Group(P < 0.05). In the S Group, postoperative long-term total bilirubin, direct bilirubin, alanine transaminase, and aspartate transaminase and postoperative serum creatinine and cystatin C levels were significantly lower than those in the T Group(P < 0.05), and postoperative albumin was significantly higher than that in the T Group(P < 0.05).CONCLUSION Compared to STPD, SSPD is a simple and easy procedure resulting in less tissue damage. Patients recovered smoothly and steadily with fewer complications. Short-term liver and kidney function damage was less severe, and long-term liver function recovery was better. Therefore, SSPD is worthy of clinical promotion and application for the treatment of PH.

关键词： Simplified pericardial devascularisation Clinical outcome Splenectomy Portal hypertension

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatic artery bridging lessens temporary ischemic injury to bile canaliculi

引用

World Journal of Gastroenterology 2015年第35期21卷 10113-10125页

作者： Jia-Zhong Wang yang Liu Jin-Long Wang Le Lu ya-fei zhang Hong-Wei Lu Yi-Ming Li Department of General Surgery the Second Affiliated HospitalXi'an Jiaotong University School of Medicine

AIM: To study whether transfer of blood between the right gastroepiploic artery and gastroduodenal artery could lessens the damage to bile ***: Forty male Bama miniature pigs were divided into four groups as follows: a control group, two hepatic artery ischemia groups(1 h and 2 h), and a hepatic artery bridging group. The hemodynamics of the hepatic artery in the hepatic artery bridging group was measured using color Doppler ultrasound. Morphological changes in the bile canaliculus were observed by transmission electron microscopy. Cofilin, heat shock protein 27 and F-actin expression was detected by immunohistochemistry, Western blot, and real-time polymerase chain reaction. Terminal deoxynucleotidyl transferase-mediated nick end-labeling method was used to evaluate liver injury. RESULTS: The hemodynamics was not changed in the hepatic artery bridging group. The microvilli in the bile canaliculus were impaired in the two hepatic artery ischemia groups. The down-regulation of cofilin and F-actin and up-regulation of heat shock protein 27 were observed in the two hepatic artery ischemia groups, while there were no significant differences between thecontrol group and hepatic artery bridging ***: Hepatic artery ischemia aggravates damage to bile canaliculi, and this damage can be diminished by a hepatic artery bridging duct.

关键词： Nonanastomotic biliary strictures Hepatic artery i

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：