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A novel flavonoid from the root of Macrothelypteris torresiana(Gaud.) Ching

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Chinese Chemical Letters 2009年第7期20卷 815-816页

作者： Ying Tang Wei Fang Yun Tao Ma ya Ling Cai Jin Lan Ruan College of Pharmacy Tongji Medical Center Huazhong University of Science and Technology Wuhan 430030 China

A novel flavonoid was isolated from the root of Macrothelypteris torresiana （Gaud.） Ching. The structure of the product was identified as 5, 7-dihydroxy-2-（1, 2-isopropyldioxy-4-oxocyclohex-5-enyl）-chromen-4-one on the ground of chemical and spectro-scopic methods.2009 Jin Lan Ruan. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： Macrothelypteris torresiana (Gaud.) Ching Flavonoid Root

Detection of K-ras gene mutation in fecal samples from elderly large intestinal cancer patients and its diagnostic significance

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World Journal of Gastroenterology 2004年第5期10卷 743-746页

作者： JunWan Zi-QiZhang Wei-diYou Hua-KuiSun Jian-PingZhang ya-Hongwang Yong-HeFu DepartmentofGeriatricGastroenterology GeneralHospitaloftheChinesePLABeijing100853China

AIM:To study the diagnostic significance of K-ras gene mutations in fecal samples from elderly patients with large intestinal ***: DNA was extracted in the fecal and tissue samples from 23 large intestinal cancer patients, 20 colonic adenomatoid polypus patients and 20 healthy subjects. The K-ras gene mutations at the first and second bases of codon 12 were detected by the allele specific mismatch ***: The K-ras gene mutation was 56.52%(13/23) in the large intestinal cancer patients, which was notably higher than that in the normal subjects whose K-ras gene mutation was 5%(1/20) (x^2=12.93, Pdifference in comparison with that of colonic adenomatoid polypus patients whose K-ras gene mutation was 30%(6/12)(x^2=3.05, P>0.05). The K-ras gene mutation at the second base of codon 12 was 92.13%(12/13) in the large intestinal cancer patients. There was no significant difference between the detection rate of K-ras gene mutation in the fecal and tissue samples (X^2=9.35, Pdicate that detection of the K-ras gene mutations in fecal samples provides a non-invasive diagnostic method for the elderly large intestinal cancer patients. Its significance in the early diagnosis of large intestinal cancer awaits further studies.

关键词： K-ras基因肠道癌肿瘤诊断学粪便标本基因错配聚合酶链反应

Effects of early rehabilitation in improvement of paediatric burnt hands function

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World Journal of Clinical Cases 2021年第32期9卷 9741-9751页

作者： ya-Qin Zhou Jun-Yi Zhou Gao-Xing Luo Jiang-Lin Tan Institute of Burn Research State Key Laboratory of TraumaBurns and Combined InjuriesChongqing Key Laboratory for Disease ProteomicsSouthwest HospitalThe Third Military Medical University(Army Medical University)Chongqing 400038China

BACKGROUND Hands are one of the most common burn sites in *** scar contractures in hands after wound healing result in further reductions in their range of motion(ROM),motility,and fine motor *** can improve the function of *** the optimal time of rehabilitation intervention is still ***,this study was designed to investigate the effects of early rehabilitation management of paediatric burnt hands and to compare the efficacy between early and later rehabilitation *** To investigate the effects of early rehabilitation management of paediatric burnt *** A total of 52 children with burnt hands were allocated into the early intervention group(≤1 mo from onset)and a late intervention group(>1 mo from onset)between January 2016 and December *** children received the same rehabilitation programme including skin care,scar massage,passive ROM exercises,active ROM exercises,compression therapy,orthotic devices wearing and game or music *** assessments were performed before and after the rehabilitation *** In the early intervention group,the ROM of the hands was significantly improved after rehabilitation(P=0.001).But in the late group the effect was not significant statistically(P=0.142).In the early group,38.5%of the patients showed significant improvement,while in the late group,69.2%of the patients showed no significant *** time from onset to posttraumatic rehabilitation(P=0.0007)and length of hospital stay(P=0.003)were negatively correlated with the hand function *** length of rehabilitation stay was positively correlated with the hand function improvement(P=0.005).CONCLUSION These findings suggest that early rehabilitation might show better results in terms of ROM.

关键词： Burns Children Rehabilitation Range of motion Hand flexion Hand extension

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长江中下游鹅头型汊道航道整治目标河型研究

水利学报 2015年第4期46卷 443-451页

作者：刘亚汪飞李义天武汉大学水资源与水电工程科学国家重点实验室湖北武汉430072 长江科学院水利部江湖治理与防洪重点实验室湖北武汉430010 长江水利委员会水文局湖北武汉430010

鹅头分汊河型由于其汊道大幅平移及主支汊频繁交替,历来是碍航问题最为突出的河段,目前关于鹅头分汊河型的治理目标存在微弯分汊和微弯单一河型的争议。本文在总结鹅头分汊河型碍航特性的基础上,结合其滩槽格局成因,从分汊河道水流能量... 详细信息

鹅头分汊河型由于其汊道大幅平移及主支汊频繁交替,历来是碍航问题最为突出的河段,目前关于鹅头分汊河型的治理目标存在微弯分汊和微弯单一河型的争议。本文在总结鹅头分汊河型碍航特性的基础上,结合其滩槽格局成因,从分汊河道水流能量守恒原理出发,提出了鹅头分汊河道航道整治的目标河型:认为进口节点的挑流作用放大了水流的年内横向摆幅,使得边滩难以长期稳定;进出口节点的存在限制了汊道的延伸平移,因此保留分汊河型是适应这一特征的必然选择。同时保持两汊较大的阻力差异,削弱主支汊格局对进口水流条件的敏感性,将更有利于主航槽的稳定,即存在一定曲率差的分汊河型是鹅头型汊道航道整治的目标河型;具体河段的汊道曲率可根据进口水力特征及进出口河床高程差计算而得。

关键词：鹅头分汊河型河床演变航道整治

Effect of body mass index on adenocarcinoma of gastric cardia

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World Journal of Gastroenterology 2003年第12期9卷 2658-2661页

作者： JiZhang Xiang-QianSu Xiao-JiangWu ya-HangLiu Huawang Xiang-NongZong Yiwang Jia-FuJi DepartmentofSurgery BeijingCancerHospitalBeijingInstituteofCancerResearchSchoolofOncologyPekingUniversityBeijing100036China DepartmentofSurgery 1stTeachingHospitalInnerMongolianMedicalSchoolHohhot010005InnerMongoliaAutonomousRegionChina

AIM: Obesity has been proved as one of the main risk factors for gastric cardia adenocarcinoma (GCA) in the *** objective of our research was to evaluate the relationship between obesity and the risk of GCA in people from North ***: A total of 300 patients who had been diagnosed as GCA and had accepted surgical operation at Beijing Cancer Hospital from 1995 to 2002 were enrolled. Data were collected from pathology materials and hospital records. Two hundred and fifty-eight healthy people who had accepted health examination at the same hospital during the same period were enrolled as controls. Height, weight and gender of them at the time of examination were also *** was estimated by body mass index (BMI), computed as weight in kilograms per square surface area (Kg/m2).The degree of obesity was determined by using BMI≤ 18.5,24-27.9 and ≥28 (Kg/m2) as the cut-off points for underweight/normal, overweight and obesity, *** with obesity were estimated by odds ratios (ORs) and 95 % confidence intervals (CIs). All ORs were adjusted for age and ***: The mean level of BMI was significantly lower in the patient group than that in the control group. The ORs for obesity in age groups 30-59 and 60-79 were 1.15 (95 %CI=0.37-3.65) and 0.16 (95 % CI=0.05-0.44) for males and 0.78 (95 % CI=0.26-2.36) and 0.28 (95 % CI=0.04-2.05)for females, respectively. The ORs for underweight were 2.42 (95 % CI=0.56-10.53) and 4.68 (95 % CI=1.13-19.40)for males in age subgroups 30-59 and 60-79 and 40.7 (95 %CI=9.32-177.92) for females older than 60 yrs. BMI was significantly associated with GCA (P＜0.01). Underweight people were at high risk for ***: BMI is an independent risk factor for *** is positively associated with GCA.

关键词：体重指数胃癌腺癌危险因子肥胖

Synthesis and Characterization of Titanosilicate with the Structure of Umbite

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Chemical Research in Chinese Universities 2002年第4期18卷 380-384页

作者： ZHAO Yong-nan LI ya-feng ZOU Yong-chun MAI Zhen-hong PANG Wen-qin Institute of Physics&Center for Condensed Matter Physics Chinese Academy of SciencesBeijing 100080P.R.China Key Laboratory of Inorganic Synthesis and Preparative Chemistry Jinlin UniversityChangchun 130023P.R.China

A zeolitic titanosilicate with the composition of K_2TiSi_3O_9·H_2O, a structural analogue of natural mineral umbite K_2ZrSi_3O_9·H_2O, was hydrothermally synthesized in the SiO_2-TiO_2-K_2O-H_2O system and characterized by means of powder X-ray diffraction, SEM, IR and thermal analysis. The effects of TiO_2/SiO_2 and OH -/SiO_2 ratios on the crystallization of the umbite were discussed. The influence of the organic additives on the morphology of the crystal was also investigated and the crystals with different shapes were obtained.

关键词： Synthesis Titanosilicate Umbite

Influence of Helicobacter pylori infection on ghrelin levels in children

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World Journal of Gastroenterology 2012年第36期18卷 5096-5100页

作者： Zhao-Hui Deng Bo Chu ya-Zhen Xu Bin Zhang Li-Rong Jiang Department of Pediatrics Shanghai Children's Medi-cal CenterShanghai Jiaotong University School of MedicineShanghai 200127China

AIM:To compare ghrelin levels in plasma and gastric mucosa before and after Helicobacter pylori(***) treatment in children with ***-associated functional ***:Children with ***-associated functional dyspepsia were enrolled in this *** infection was confirmed by positive bacterial culture *** of the children received triple *** eradication therapy(a 2 wk course of omeprazole,amoxicillin,and clarithromycin).The children were divided into two groups based on the success of the *** treatment:group 1(eradicated)-patients who had a negative 13C-urea breath test 2 mo after the end of therapy;and group 2(non-eradicated)-patients who had a positive 13C-urea breath *** ghrelin,gastric ghrelin mRNA,and the body mass index were evaluated in both groups before and after the *** *** plasma ghrelin levels were measured by a *** expression of gastric ghrelin mRNA was determined by real-time reverse transcription polymerase chain ***:A total of 50 children with ***-associated functional dyspepsia were treated with triple *** eradication *** mean age of the children was 5.52 ± 0.83 years,and there were 28 males and 22 *** the 50 ***-positive children,30 successfully achieved eradication,and 20 did *** mean plasma ghrelin levels of group 1 were 22.17 ± 1.73 ng/L and 26.59 ± 2.05 ng/L before and after the treatment,respectively,which was a significant increase(P = 0.001).However,the mean plasma ghrelin level of group 2 before and after the *** treatment was 21.34 ± 2.40 ng/L and 22.24 ± 2.10 ng/L(P = 0.785).The plasma ghrelin levels increased substantially after treatment in group 1 but showed only minor changes in group ***,the gastric ghrelin mRNA expression in group 1 before treatment was 2.84 ± *** treatment,the level was 3.11 ± 0.65,which was significantly different(P = 0.023).The gastric ghrelin mRNA expression in g

关键词： Helicobacter pylori Functional dyspepsia Ghrelin Eradication Children

An Effective differential Fault Analysis on the Serpent Cryptosystem in the Internet of Things

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China Communications 2014年第6期11卷 129-139页

作者： LI Wei TAO Zhi GU Dawu SUN Li QU Bo LIU Zhiqiang LIU ya School of Computer Science and Technology Donghua University Department of Computer Science and Engineering Shanghai Jiao Tong University State Key Laboratory of Information Security Institute of Information Engineering Chinese Academy of Sciences Shanghai Key Laboratory of Integrate Administration Technologies for Information Security Network Architectures and Services Delft University of Technology Mekelweg 4 2628 CD Delft The Netherlands ESAT/COSIC and IBBT Katholieke Universiteit Leuven Department of Computer Science and Engineering University of Shanghai for Science and Technology

Due to the strong attacking ability, fast speed, simple implementation and other characteristics, differential fault analysis has become an important method to evaluate the security of cryptosystem in the Internet of Things. As one of the AES finalists, the Serpent is a 128-bit Substitution-Permutation Network(SPN) cryptosystem. It has 32 rounds with the variable key length between 0 and 256 bits, which is flexible to provide security in the Internet of Things. On the basis of the byte-oriented model and the differential analysis, we propose an effective differential fault attack on the Serpent cryptosystem. Mathematical analysis and simulating experiment show that the attack could recover its secret key by introducing 48 faulty ciphertexts. The result in this study describes that the Serpent is vulnerable to differential fault analysis in detail. It will be beneficial to the analysis of the same type of other iterated cryptosystems.

关键词： internet of things cryptanalysis differential fault analysis serpent.

Crossover from normal to diffused and relaxor ferroelectric in BaZrO_(3)- modified (Ba_(0.85)Ca_(0.15))TiO_(3) ceramics

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Journal of Materiomics 2021年第5期7卷 1094-1102页

作者： Shao Bo Chen Jia Yi yang Shu ya Wu Xiang Ming Chen Laboratory of dielectric Materials School of Materials Science and EngineeringZhejiang University38 Zheda RoadHangzhou310027China

The variation of dielectric,ferroelectric and piezoelectric characteristics of BaZrO_(3)emodified(Ba_(0.85)Ca_(0.15))TiO_(3) ceramics,(1-x)(Ba_(0.85)Ca_(0.15))TiO_(3)-xBaZrO_(3),have been investigated together with the structure *** crystal structure at room-temperature varies from tetragonal to metrically cubic through orthorhombic and rhombohedral,and the morphotropic phase boundary(MPB)is determined around x=0.12 where the significantly enhanced dielectric,ferroelectric and piezoelectric characteristics are *** increasing x,the present ceramics indicate the crossover from normal to diffused and relaxor ferroelectric,and the evolution process is explored systematically.

关键词： Morphotropic phase boundary diffused ferroelectric Relaxor ferroelectric