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Comparison of feasibility,microstructure and performance of hybrid laser arc,activated flux tungsten inert gas and friction stir welding for thick plate of innovative ultra-pure ferritic stainless steel

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Journal of Iron and Steel Research International 2022年第4期29卷 665-676页

作者： Jian Han Lian-meng Liu xin-ya chen Min-fang chen Lei Cui yang-chuan Cai Yin-bao Tian School of Materials Science and Engineering Tianjin University of TechnologyTianjin 300384China School of Materials Science and Engineering Tianjin UniversityTianjin 300072China

An innovative grade of ferritic stainless steel,ultra-pure 18Cr–2Mo thick plate,was designed and produced for special industrial *** order to maintain its mechanical properties after joining,three advanced joining methods,hybrid laser arc welding,activated flux tungsten inert gas welding and friction stir welding,were selected and conducted to connect the thick *** feasibility of three joining methods,the microstructure and mechanical properties were compared,and the results have demonstrated that the sound joint was successfully produced using the selected parameters through friction stir *** obtained hardness and impact toughness of the weld zone were *** terms of activated flux tungsten inert gas welding,the crack will be created due to microstructural *** as for hybrid laser arc welding,the weld zone is narrow,and the addition of wire during welding for the top weld metal area leads to higher formation ratio of low-angle grain boundaries,which is beneficial to performance of the ***,there is still a weak area in the fusion line of the welded *** result has illustrated that the welding of innovative ultra-pure ferritic stainless steel thick plate by friction stir welding is feasible.

关键词： Ultra-pure ferritic stainless steel Hybrid welding Activated flux tungsten inert gas Friction stir welding Microstructural evolution Mechanical property

Theoretical and experimental study of phase optimization of tapping mode atomic force microscope

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Chinese Physics B 2022年第7期31卷 469-476页

作者： Zheng Wei An-Jie Peng Feng-Jiao Bin ya-xin chen Rui Guan College of Mechanical and Electrical Engineering Beijing University of Chemical TechnologyBeijing 100029China

Phase image in tapping-mode atomic force microscope(TM-AFM)results from various dissipations in a microcantilever *** phases mainly reflect the tip-sample contact dissipations which allow the nanoscale characteristics to be distinguished from each *** this work,two factors affecting the phase and phase contrast are *** is concluded from the theoretical and experimental results that the phases and phase contrasts in the TM-AFM are related to the excitation frequency and energy dissipation of the *** a two-component blend,it is theoretically and experimentally proven that there exists an optimal excitation frequency for maximizing the phase ***,selecting the optimal excitation frequency can potentially improve the phase contrast *** addition,only the key dissipation between the tip and sample is found to accurately reflect the sample ***,the background dissipation can potentially reduce the contrasts of the phase images and even mask or distort the effective information in the phase *** order to address the aforementioned issues,a self-excited method is adopted in this study in order to eliminate the effects of the background dissipation on the ***,the real phase information of the samples is successfully *** is shown in this study that the eliminating of the background dissipation can effectively improve the phase contrast results and the real phase information of the samples is accurately *** results are of great significance in optimizing the phases of two-component samples and multi-component samples in atomic force microscope.

关键词： TM-AFM phase image excitation frequency energy dissipation

Recent advances and perspectives on prelithiation strategies for lithium-ion capacitors

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Rare Metals 2022年第10期41卷 3322-3335页

作者： Jiang-Min Jiang Zhi-Wei Li Zhao-Ting Zhang Shi-Jing Wang Hai Xu xin-Ran Zheng ya-xin chen Zhi-cheng Ju Hui Dou Xiao-Gang Zhang Jiangsu Key Laboratory of Electrochemical Energy Storage Technology College of Material Science and EngineeringNanjing University of Aeronautics and AstronauticsNanjing210016China Jiangsu Key Laboratory of Coal-Based Greenhouse Gas Control and Utilization School of Materials Science and PhysicsChina University of Mining and TechnologyXuzhou221116China Department of Physics National University of SingaporeSingapore117574Singapore Tsinghua Shenzhen International Graduate School Tsinghua UniversityShenzhen518055China

Lithium-ion capacitors(LICs),consisting of a capacitor-type material and a battery-type material together with organic electrolytes,are the state-of-the-art electrochemical energy storage devices compared with supercapacitors and *** to their unique characteristics,LICs received a lot of attentions,and great progresses have been achieved,especially in the exploration of cathode and anode *** techniques are regarded as indispensable procedures for LICs systems,which can compensate for the initial irreversible capacity loss,increase the Li^(+)concentration in the electrolyte,raise the working voltage and resolve the safety and cycle stability issues;however,its research progress is slow,and there is not enough attention until *** this overview,we look into the ongoing processes on the recent development of prelithiation technologies,especially in organic electrolyte consumption-type *** particular,some prelithiation strategies for LICs are summarized and discussed in detail,including the ex situ electrochemical method,in situ electrochemical method,and cathode prelithiation additives ***,we propose some unresolved challenges and prospects for prelithiation technologies from the basic research ideas and future key research *** work aims to bring up new insights to reassess the significance of premetallation strategies for advanced hybrid-ion capacitors based on the currently proposed prelithiation strategies.

关键词： Lithium-ion capacitors(LICs) Prelithiation Initial irreversible capacity Stabilized lithium metal powder Self-sacrificial additives

Co-adsorption behavior of aggregated asphaltenes and silica nanoparticles at oil/water interface and its effect on emulsion stability

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Petroleum Science 2022年第4期19卷 1793-1802页

作者： Guang-Yu Sun Hao Zhang Dai-Wei Liu Chuan-Xian Li Fei yang Bo yao Ze Duan xin-ya chen Fu-Jun Sheng College of Pipeline and Civil Engineering China University of Petroleum(East China)Qingdao266580ShandongPeople's Republic of China Shandong Key Laboratory of Oil&Gas Storage and Transportation Safety Qingdao266580ShandongPeople's Republic of China

In petroleum industry, crude oil emulsions are commonly formed in oilfields. The asphaltenes and fine particles in crude oil may affect the stability of the emulsions by adsorbing at the water/oil interface. In this research, the effect of silica nanoparticles and asphaltenes on emulsion stability is explored first. The asphaltenes are proved to benefit emulsion stability. Unlike the asphaltenes, however, the modified silica nanoparticles may have positive or negative effect on emulsion stability, depending on the asphaltene concentration and aggregation degree in the emulsions. Further, it is confirmed by conducting interfacial experiment that the asphaltenes and particles can adsorb at the interface simultaneously and determine the properties of the interfacial layer. More in-depth experiments concerning contact angle and asphaltene adsorption amount on the particles indicate that the asphaltenes can modify the wettability of the particles. Higher concentration and lower aggregation degree of the asphaltenes can increase their adsorption amount on the surface of particles and then improve the modification effectiveness of the particles. Resultantly, the particles with good modification effectiveness can enhance the emulsion stability while the particles with poor modification effectiveness will weaken the emulsion stability.

关键词： Asphaltene Silica nanoparticle Co-adsorption behavior Modification effectiveness Emulsion stability

Quantitative prediction model for the depth limit of oil accumulation in the deep carbonate rocks:A case study of Lower Ordovician in Tazhong area of Tarim Basin

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Petroleum Science 2024年第1期21卷 115-124页

作者： Wen-yang Wang Xiong-Qi Pang ya-Ping Wang Zhang-xin chen Fu-Jie Jiang Ying chen State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing100029China State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing102249China College of Geosciences China University of Petroleum(Beijing)Beijing102249China Research Institute of Exploration and Development PetroChina Southwest Oil&Gas Field CompanyChengdu610041SichuanChina Chemical and Petroleum Engineering Schulich School of EngineeringUniversity of CalgaryCalgaryT2N 1N4Canada

With continuous hydrocarbon exploration extending to deeper basins,the deepest industrial oil accumulation was discovered below 8,200 m,revealing a new exploration ***,the extent to which oil exploration can be extended,and the prediction of the depth limit of oil accumulation(DLOA),are issues that have attracted significant attention in petroleum *** it is difficult to characterize the evolution of the physical properties of the marine carbonate reservoir with burial depth,and the deepest drilling still cannot reach the ***,the DLOA cannot be predicted by directly establishing the relationship between the ratio of drilling to the dry layer and the *** this study,by establishing the relationships between the porosity and the depth and dry layer ratio of the carbonate reservoir,the relationships between the depth and dry layer ratio were obtained *** depth corresponding to a dry layer ratio of 100%is the *** on this,a quantitative prediction model for the DLOA was finally *** results indicate that the porosity of the carbonate reservoir,Lower Ordovician in Tazhong area of Tarim Basin,tends to decrease with burial depth,and manifests as an overall low porosity reservoir in deep *** critical porosity of the DLOA was 1.8%,which is the critical geological condition corresponding to a 100%dry layer ratio encountered in the *** depth of the DLOA was 9,000 *** study provides a new method for DLOA prediction that is beneficial for a deeper understanding of oil accumulation,and is of great importance for scientific guidance on deep oil drilling.

关键词： Deep layer Tarim Basin Hydrocarbon accumulation Depth limit of oil accumulation Prediction model

Application of Fusobacterium nucleatum as a biomarker in gastrointestinal malignancies

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2271-2283页

作者： Long-chen Yu ya-Ping Li Yue-Ming xin Mai Mao ya-xin Pan Yi-Xuan Qu Zheng-Dong Luo Yi Zhang xin Zhang Department of Clinical Laboratory Qilu Hospital of Shandong UniversityShandong Engineering Research Center of Biomarker and Artificial Intelligence ApplicationJinan 250012Shandong ProvinceChina

The morbidity and mortality of gastrointestinal(GI)malignancies are among the highest in the world,posing a serious threat to human *** of the insidious onset of the cancer,it is difficult for patients to be diagnosed at an early stage,and it rapidly progresses to an advanced stage,resulting in poor treatment and *** nucleatum(***)is a gram-negative,sporefree anaerobic bacterium that primarily colonizes the oral cavity and is implicated in the development of colorectal,esophageal,gastric,and pancreatic cancers via various intricate *** development in novel research suggests that *** may function as a biomarker in GI *** the abundance of *** in stool,saliva,and serum samples of patients may aid in the diagnosis,risk assessment,and prognosis monitoring of GI *** editorial systematically describes the biological roles and mechanisms of *** in GI malignancies focusing on the application of *** as a biomarker in the diagnosis and prognosis of GI malignancies to promote the clinical translation of *** and GI tumors-related research.

关键词： Gastrointestinal malignancies Fusobacterium nucleatum Biomarker Diagnosis Prognosis

Retinitis pigmentosa and stem cell therapy

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International Journal of Ophthalmology(English edition) 2024年第7期17卷 1363-1369页

作者： xin-ya Qi chen-Hui Mi De-Rui Cao Xie-Qun chen Peng Zhang School of Medicine Department of Life Sciences and MedicineNorthwest UniversityXi’an 710069Shaanxi ProvinceChina The Third Hospital of Xi’an Affiliated Hospital of Northwest UniversityXi’an 710021Shaanxi ProvinceChina

Retinitis pigmentosa(RP)is a group of genetic disorders characterized by progressive degeneration of photoreceptors and retinal pigment epithelium(RPE)*** main clinical manifestations include night blindness and progressive loss of peripheral vision,making it a prevalent debilitating eye disease that significantly impacts patients’quality of *** exhibits significant phenotypic and genetic *** instance,numerous abnormal genes are implicated in RP,resulting in varying clinical presentations,disease progression rates,and pathological characteristics among different ***,gene therapy for RP poses challenges due to these ***,stem cells have garnered considerable attention in the field of RPE therapy since both RPE cells and photoreceptors can be derived from stem *** recent years,a large number of animal experiments and clinical trials based on stem cell transplantation attempts,especially cord blood mesenchymal stem cell(MSC)transplantation and bone marrow-derived MSC transplantation,have confirmed that stem cell therapy can effectively and safely improve the outer retinal function of the RP-affected ***,stem cell therapy also has certain limitations,such as the fact that RP patients may involve multiple types of retinal cytopathia,which brings great challenges to stem cell transplantation therapy,and further research is needed to solve various problems faced by this approach in the *** comprehensive analysis of the etiology and histopathological changes associated with RP,this study substantiates the efficacy and safety of stem cell therapy based on rigorous animal experimentation and clinical trials,while also highlighting the existing limitations that warrant further investigation.

关键词： retinitis pigmentosa photoreceptor stem cell therapy

11-Aza-artemisinin Derivatives Exhibit Anticancer Activities by Targeting the Fatty Acid Binding Protein 6(FABP6)

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Chinese Journal of Chemistry 2018年第12期36卷 1197-1201页

作者： xin-ya chen Yue Yin Jie Xi Yi Yuan yan Li Qing Li Ren-Xiao Wang Zhu-Jun yao Gong-Li Tang State Key Laboratory of Bio-organic and Natural Products Chemistry Shanghai Institute of Organic ChemistryChinese Academy of Sciences345 Lingling RoadShanghai 200032China State Key Laboratory of Coordination Chemistry Jiangsu Key Laboratory of Advanced Organic MaterialsSchool of Chemistry and Chemical EngineeringNanjing University163 Xianlin AvenueNanjingJiangsu 210023China

Artemisinin (Qinghaosu), a sesquiterpene lactone isolated from the Chinese medicinal herb Artemisia annua , is famous as the first‐line antimalarial drug, and reported to also possess anticancer properties. Though many studies have proceeded focusing on artemisinin and bioactive derivatives in clinic or laboratory, their cellular targets and mechanism of actions have still remained obscure. Here, two new 11‐aza‐artemisinin derivatives AAD1 and AAD2, which displayed cytotoxity against multiple cancer cell lines, were synthesized and applied as the probes for target identification and anticancer mechanism research. Using T7 phage display screen method, fatty acid binding protein 6 (FABP6) was identified and verified as one of the potential targets. Further studies showed FABP6 is a direct binding protein of AAD1 and AAD2, and mediated the corresponding anticancer activities of these artemisinin derivatives.

关键词： artemisinin derivatives biological activity apoptosis phage display target FABP6 molecule‐protein interaction

Dominant woody plant species recognition with a hierarchical model based on multimodal geospatial data for subtropical forests

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Journal of Forestry Research 2024年第3期35卷 111-130页

作者： xin chen Yujun Sun State Forestry&Grassland Administration Key Laboratory of Forest Resources&Environmental Management Beijing Forestry UniversityBeijing 100083People's Republic of China

Since the launch of the Google Earth Engine(GEE)cloud platform in 2010,it has been widely used,leading to a wealth of valuable ***,the potential of GEE for forest resource management has not been fully *** extract dominant woody plant species,GEE combined Sen-tinel-1(S1)and Sentinel-2(S2)data with the addition of the National Forest Resources Inventory(NFRI)and topographic data,resulting in a 10 m resolution multimodal geospatial dataset for subtropical forests in southeast *** and texture features,red-edge bands,and vegetation indices of S1 and S2 data were computed.A hierarchical model obtained information on forest distribution and area and the dominant woody plant *** results suggest that combining data sources from the S1 winter and S2 yearly ranges enhances accuracy in forest distribution and area extraction compared to using either data source ***,for dominant woody species recognition,using S1 winter and S2 data across all four seasons was *** terrain factors and removing spatial correlation from NFRI sample points further improved the recognition *** optimal forest extraction achieved an overall accuracy(OA)of 97.4%and a maplevel image classification efficacy(MICE)of 96.7%.OA and MICE were 83.6%and 80.7%for dominant species extraction,*** high accuracy and efficacy values indicate that the hierarchical recognition model based on multimodal remote sensing data performed extremely well for extracting information about dominant woody plant *** the results using the GEE application allows for an intuitive display of forest and species distribution,offering significant convenience for forest resource monitoring.

关键词： Google Earth Engine Sentinel Forest resource inventory data Dominant woody plant species Subtropics Model performance