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Molecular Plant 2016年第3期9卷 461-470页

作者： Shuan Meng Jia-Shi Peng ya-ni he Guo-Bin Zhang Hong-Ying Yi yan-Lei Fu Ji-Ming Gong National Key Laboratory of Plant Molecular Genetics National Center for Plant Gene Research (Shanghai) CAS Center for Excellence in Molecular Plant Sciences Institute of Plant Physiology and Ecology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai 200032 People's Republic of China

nitrogen deficiency induces leaf senescence. However, whether or how nitrate might affect this process remains to be investigated. here, we report an interesting finding that nitrate-- instead of nitrogen--starvation induced early leaf senescence in nrtf.5 mutant, and present genetic and physiological data demon-strating that nitrate starvation-induced leaf senescence is suppressed by NRTI.5. NRT1.5 suppresses the senescence process dependent on its function from roots, but not the nitrate transport function. Further analyses using nrt1.5 single and nial nia2 nrt1.5-4 triple mutant showed a negative correlation between nitrate concentration and senescence rate in leaves. Moreover, when exposed to nitrate starvation, foliar potassium level decreased in nrt1.5, but adding potassium could essentially restore the early leaf senescence phenotype of nrt1.5 plants. nitrate starvation also downregulated the expression of HAK5, RAP2.11, and ANN1 in nrt1.5 roots, and appeared to alter potassium level in xylem sap from nrt1.5. These data suggest that NRT1.5 likely perceives nitrate starvation-derived signals to prevent leaf senescence by facilitating foliar potassium accumulation.

关键词： Leaf Senescence NRT1.5 nitrate Starvation Potassium

Transjugular intrahepatic portosystemic shunt:A promising therapy for recompensation in cirrhotic patients

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World Journal of Gastroenterology 2024年第16期30卷 2285-2286页

作者： ya-ni Jin Wei Zhang Department of Gastroenterology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjing 210000Jiangsu ProvinceChina

This is a retrospective study focused on recompensation after transjugular intrahepatic portosystemic shunt(TIPS)*** authors confirmed TIPS could be a treatment for recompensation of patients with cirrhosis according to Baveno *** paper identified age and post-TIPS portal pressure gradient as independent predictors of recompensation in patients with decompensated cirrhosis after *** results need to be validated in a larger prospective cohort.

关键词： Cirrhosis recompensation Transjugular intrahepatic portosystemic shunt Portal pressure gradient Predictor factor Baveno VII

Ecological Network Resilience of Shiyang River Basin: An Arid Inland Watershed of Northwest China

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Chinese Geographical Science 2024年第5期34卷 951-966页

作者： he yangxi LIU Chunfang ni Bowen LIAN Hugang School of Management Northwest Normal UniversityLanzhou 730070China Research Center of Land Use and Comprehensive Improvement Engineering of Gansu Province Lanzhou 730070China

Due to the uncertainties posed by climate change,resilience has become an increasingly important variable for evaluating regional ecosystem *** assessment of Ecological Network Resilience(ENR)is crucial for establishing mitigation strategies and sustainable socioeconomic development in arid *** River Basin is an arid watershed in Northwest China with complex characteristics,its ENR and spatial differentiation characteristics in 2020 were investigated in this work based on the Complex Adaptive System(CAS)*** results indicated that the mean Ecological Network Resilience Index(ENRI)value for the Shiyang River Basin was 0.390 in 2020,and the mean values in the southern mountainous,middle oasis,and northern desert regions of the basin were 0.598,0.461,and 0.237,respectively,demonstrating evident spatial ***,the ENR of the basin exhibited distinct distribution characteristics across different dimension,whereas the trend of the integrated ENR of the basin was consistent with that of elemental,structural,and functional resilience,indicating the constructed three-region ENR model based on the logical relationship of element-structure-function was suitable for evaluation of the ENR in arid inland river ***,strategies for enhancing regional ENR were proposed from the perspective of adapting to climate change.

关键词： Ecological Network Resilience(ENR) Complex Adaptive System(CAS) element-structure-function Shiyang River Basin Northwest China

pH Induced Self-assembly of AIE Fluorescent Probe for Tumor Imaging

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Chinese Journal of Polymer Science 2024年第1期42卷 7-13,I0005页

作者： Jing-Yuan Xiang Wen-Long Zhang he-Ting Li ya-ning he Department of Chemical Engineering Key Laboratory of Advanced Materials(MOE)Tsinghua UniversityBejing 100084China

This work reported an AIE fluorescent probe for tumor imaging based on the p H induced self-assembly strategy. The fluorescent probe was composed of an acid-responsive soluble copolymer PEG-b-PAMA-DMMA with a maleic acid amide group and an anionic soluble aggregation-induced emission fluorogen(AIEgen) TPE-2SO_(3)^(-). The polymer could be transformed into a protonated amine-containing polymer after the hydrolysis of maleic acid amide in acidic tumor microenvironment, which would be further self-assembled with TPE-2SO_(3)^(-)to form aggregated nanoparticles. The transition of TPE-2SO_(3)^(-)from dispersed state to aggregated state led to an obvious increase in fluorescence intensity due to its AIE characteristics.

关键词： p H-responsive Self-assembly Fluorescent probe AIE Tumor imaging

Fabricating functionally graded Fe-Cr-Co permanent magnetic alloys via laser powder bed fusion

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Journal of Iron and Steel Research International 2024年第3期31卷 729-737页

作者： ya-zhou he ya-qing Hou Peng Shen Hao Zhang Dong Zhou Hang Su Central Iron and Steel Research Institute Co. Ltd.Beijing 100081China Material Digital R&D Center China Iron and Steel Research Institute Group Co.Ltd.Beijing 100081China

Laser powder bed fusion(LPBF)in-situ alloying technology offers the possibility to construct gradient materials with varied structures and *** graded Fe-Cr-Co permanent magnetic alloys were fabricated by LPBF and in-situ alloying mixed powders of Fe,Cr,and Co *** effects of different Fe,Cr and Co contents on the microstructure,magnetic properties and hardness of Fe-Cr-Co alloys prepared by LPBF were *** as-built Fe-Cr-Co alloys present a single body-centered-cubic phase and have a homogeneous distribution of *** mechanical properties and magnetic properties of the compositionally graded sample show a gradient *** the increase in Cr content,the Vickers hardness of the sample increases,and the saturation magnetization of the sample *** optimal magnetic properties in an isotropic state are given as coercivity HcB=21.65 kA/m,remanence Br=0.70 T and energy product(BH)_(max)=5.35 kJ/m^(3),which are comparable to or higher than the reported magnetic properties in an isotropic state prepared by traditional powder *** in-situ alloying technology has the potential to further explore Fe-Cr-Co magnetic materials,such as those consisting of multiple or more constituent elements,and to maximize the compositional flexibility of magnetic materials.

关键词： Fe-Cr-Co alloy Laser powder bed fusion In-situ alloying Functional material Magnetic property

Numerical study on the effective thermal conductivity and thermal tortuosity of porous media with different morphologies

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Science China(Technological Sciences) 2024年第6期67卷 1685-1694页

作者： DU Shen LI Dong LI Meng-Jie he ya-Ling Key Laboratory of Thermo-Fluid Science and Engineering of Ministry of Education School of Energy and Power EngineeringXi’an Jiaotong UniversityXi’an710049China

Effective thermal conductivity and thermal tortuosity are crucial parameters for evaluating the effectiveness of heat conduction within porous *** direct pore-scale numerical simulation method is applied to investigate the heat conduction processes inside porous structures with different *** thermal conduction performances of idealized porous structures are directly compared with real foams across a wide range of *** foam structures are reconstructed using X-ray computed tomography and image processing techniques,while Kelvin and Weaire-Phelan structures are generated through periodic unit cell *** detailed temperature fields inside the porous structures are determined by solving the heat conduction equation at the pore *** results present that the equivalent thermal conductivity of Kelvin and Weaire-Phelan structures is similar to and greater than that of the real foam structure with the same strut *** thermal tortuosity of real foam structure is relatively larger and the heat conduction path becomes straighter by adopting the anisotropic *** thermal tortuosity of the fluid channels for Kelvin,Weaire-Phelan,and real foam structures is close to *** thermal conductivity of porous structures with heat transfer fluid increases as the thermal conductivity ratio of fluid to solid becomes larger.A small porosity of porous media leads to a larger equivalent thermal conductivity due to the dominant contribution of porous skeleton in the heat conduction *** derived from parallel and series models,as well as the Maxwell-Eucken models,provide decent predictions of effective thermal conductivity,with an average error of less than 8%in the entire range of thermal conductivity ratio.

关键词： volumetric solar receiver porous morphology direct pore-scale simulation equivalent thermal conductivity thermal tortuosity empirical correlation

Influence of secondary lining thickness on mechanical behaviours of double-layer lining in large-diameter shield tunnels

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Underground Space 2024年第5期18卷 130-150页

作者： Shimin Wang Xuhu he Xiaoyu Peng ya Wang Zhengxin Li Zihan Song Key Laboratory of Transportation Tunnel Engineering Ministry of EducationSouthwest Jiaotong UniversityChengdu 610031China School of Civil Engineering Southwest Jiaotong UniversityChengdu 610031China

In large-diameter shield tunnels,applying the double-layer lining structure can improve the load-bearing properties and maintain the stability of segmental *** secondary lining thickness is a key parameter in the design of a double lining structure,which is worth being *** on an actual large-diameter shield tunnel,loading model tests are carried out to investigate the effect of the secondary lining thickness on the mechanical behaviours of the double lining *** test results show that within the range of secondary lining thicknesses discussed,the load-bearing limit of the double-layer lining increases with growing secondary lining *** a passive support,the secondary lining acts as an auxiliary load-bearing structure by contacting the *** changes in secondary lining thickness have a significant effect on the contact state between the segment and secondary lining,with both the contact pressure level and the contact area between the two *** double-layer lining structures in large-diameter shield tunnels,it is proposed that the stiffness of the secondary lining needs to be matched to the stiffness of the segment,as this allows them to have a coordinated deformation and a good joint load-bearing effect.

关键词： Large-diameter shield tunnels Double-layer lining structure Secondary lining thickness Stiffness matching Similar model test

Structural transformation from Waugh-type to Keggin-type polyoxomolybdate-based crystalline material for photo/electrocatalysis

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Rare Metals 2024年第5期43卷 2241-2250页

作者： Pei-Sen Wang Zi-Tong Wang ya-ya Tan Peng Chen Xue-Cheng Zhang Lu-Nan Zhang Yong-Ge Wei Lu-Bin ni School of Chemistry and Chemical Engineering Yangzhou UniversityYangzhou 225002China Key Lab of Organic Optoelectronics and Molecular Engineering of Ministry of Education Department of ChemistryTsinghua UniversityBeijing 100084China State Key Laboratory of Natural and Biomimetic Drugs Peking UniversityBeijing100191China

An inorganicDorganic hybrid crystalline material(SiMo_(12)O_(40))[Cu(2,2'-bipy)_(2)]_(2)·2H_(2)O(Complex 1,2,2'-bipy=2,2'-bipyridine)was synthesized for the first time by using 2,2'-bipy and transition metal copper to convert Waugh-type polyoxometalate[MnMo_(9)O_(3)_(2)]_(6-)into a Keggin polyoxometalate structure[SiMo_(12)O_(40)]^(4-)under hydrothermal conditions in glass *** crystal tests and a series of characterizations were carried out on Complex *** structure of Complex 1 is composed of[SiMo_(12)O_(40)]^(4-)and[Cu^(Ⅱ)(2,2'-bipy)_(2)]^(2+).The five-coordinated Cu is connected to two 2,2'-bipy through CuDN bonds,forming an approximately square ***,Complex 1 exhibited good photocatalytic performance for methylene blue degradation and electrocatalytic nitrite reduction properties simultaneously.

关键词： Polyoxometalates Inorganic-organic hybrid materials Photocatalytic Electrocatalytic

Therapeutic Role of Chinese Medicine Targeting Nrf2/HO-1 Signaling Pathway in Myocardial Ischemia/Reperfusion Injury

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Chinese Journal of Integrative Medicine 2024年第10期30卷 949-960页

作者： LIU Chang-xing GUO Xin-yi ZHOU ya-bin WANG he First Clinical Medical School Heilongjiang University of Chinese MedicineHarbin150040China Clinical Medical School Chengdu University of Traditional Chinese MedicineChengdu610036China Department of Cardiology the First Affiliated Hospital of Heilongjiang University of Chinese MedicineHarbin150040China

Acute myocardial infarction(AMI),characterized by high incidence and mortality rates,poses a significant public health *** therapy,though the preferred treatment for AMI,often exacerbates cardiac damage,leading to myocardial ischemia/reperfusion injury(MI/RI).Consequently,the development of strategies to reduce MI/RI is an urgent priority in cardiovascular *** medicine,recognized for its multi-component,multi-pathway,and multi-target capabilities,provides a novel approach for alleviating MI/RI.A key area of interest is the nuclear factor E2-related factor 2(Nrf2)/heme oxygenase-1(HO-1)*** pathway is instrumental in regulating inflammatory responses,oxidative stress,apoptosis,endoplasmic reticulum stress,and ferroptosis in MI/*** paper presents a comprehensive overview of the Nrf2/HO-1 signaling pathway's structure and its influence on MI/***,it reviews the latest research on leveraging Chinese medicine to modulate the Nrf2/HO-1 pathway in MI/RI treatment.

关键词： nuclear factor E2-related factor 2/heme oxygenase-1 signaling pathway myocardial ischemia/reperfusion injury Chinese medicine mechanisms

Survival Analysis of Patients Undergoing Intraoperative Contrast-enhanced Ultrasound in the Surgical Treatment of Malignant Glioma

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Current Medical Science 2024年第2期44卷 399-405页

作者： Xu CheN ya-ni PENG Fang-ling CheNG Dan CAO An-yu TAO Jian CheN Department of Neurosurgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Urology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Medical Ultrasound Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Objective:Complete resection of malignant gliomas is often *** previous study indicated that intraoperative contrast-enhanced ultrasound(ICEUS)could aid in the detection of residual tumor remnants and the total removal of brain *** study aimed to investigate the survival rates of patients undergoing resection with or without the use of ICEUS and to assess the impact of ICEUS on the prognosis of patients with malignant ***:A total of 64 patients diagnosed with malignant glioma(WHO grade HI and IV)who underwent surgery between 2012 and 2018 were *** them,29 patients received *** effects of ICEUS on overall survival(OS)and progression-free survival(PFS)of patients were evaluated.A quantitative analysis was performed to compare ICEUS parameters between gliomas and the surrounding ***:The ICEUS group showed better survival rates both in OS and PFS than the control *** univariate analysis revealed that age,pathology and ICEUS were significant prognostic factors for PFS,with only age being a significant prognostic factor for *** multivariate analysis,age and ICEUS were significant prognostic factors for both OS and *** quantitative analysis showed that the intensity and transit time of microbubbles reaching the tumors were significantly different from those of microbubbles reaching the surrounding ***:ICEUS facilitates the identification of residual *** and ICEUS are prognostic factors for malignant glioma surgery,and use of ICEUS offers a better prognosis for patients with malignant glioma.

关键词： intraoperative contrast-enhanced ultrasound malignant glioma extent of resection survival prognosis